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TOPIC	
  5:	
  	
  
MUSCULO-­‐SKELETAL	
  SYSTEM	
  
Learning	
  outcomes	
  
1.  IdenAfy	
  types	
  of	
  muscle	
  Assues	
  
2.  Describe	
  types	
  of	
  skeletal	
  system	
  
3.  IdenAfy	
  human	
  skeletal	
  system	
  
4.  IdenAfy	
  the	
  component	
  of	
  	
  human	
  musculo-­‐skeletal	
  system	
  
5.  Explain	
  how	
  muscle	
  contracts	
  
6.  Describe	
  muscle	
  and	
  bone	
  relaAonships	
  
topic	
  
1.  Muscle	
  bone	
  partnership	
  
2.  Types	
  of	
  muscle	
  Assue	
  
3.  Muscle	
  contracAon	
  
4.  Skeletal	
  system	
  
5.  Musculo-­‐skeletal	
  system	
  
THE	
  MUSCLE–BONE	
  PARTNERSHIP	
  
The	
  muscle–bone	
  partnership	
  
•  Skeletal	
  muscles	
  are	
  bundles	
  of	
  muscle	
  fibers	
  that	
  interact	
  
with	
  bones	
  and	
  with	
  one	
  another	
  	
  
•  Tendons	
  aQach	
  skeletal	
  muscles	
  to	
  bones	
  
AcAon	
  of	
  muscle:	
  
Example:	
  Movement	
  of	
  the	
  forearm	
  at	
  the	
  elbow	
  joint	
  
1.  When	
  muscle	
  contract	
  they	
  shorter	
  
2.  When	
  muscle	
  relaxed,	
  they	
  longer	
  
3.  Muscle	
  only	
  pull;	
  they	
  cannot	
  push.	
  
4.  Both	
  muscle	
  work	
  in	
  antagonisAc	
  pairs	
  
Synergy	
  Muscle	
  
• Some cause movements by working as pairs or groups (synergy)
• Synergy muscle assist prime mover
Antagonist	
  Muscle	
  
Others oppose or reverse the action of a partner muscle (antagonist)
TYPES	
  OF	
  MUSCLE	
  TISSUE	
  
Muscle	
  Tissues:	
  Move	
  the	
  Body	
  
•	
  	
  Muscle	
  Assues	
  are	
  frequently	
  called	
  
contracAle	
  Assues	
  because	
  they	
  contain	
  
contracAle	
  protein	
  filaments	
  such	
  as	
  acAn	
  and	
  
myosin.	
  
•  There	
  are	
  three	
  types	
  of	
  muscle	
  Assues.	
  
1.  Skeletal	
  
2.  Cardiac	
  
3.  Smooth	
  
1.	
  Skeletal	
  Muscle	
  
•  There	
  are	
  3	
  types	
  of	
  muscle	
  in	
  the	
  
human	
  body,	
  each	
  with	
  a	
  different	
  
structure.	
  
1.  Cardiac	
  muscle,	
  found	
  in	
  
the	
  heart,	
  consists	
  of	
  
striated,	
  branched	
  cells	
  
forming	
  a	
  la[ce.	
  
2.  	
  Smooth	
  muscle	
  are	
  long,	
  
spindle-­‐shaped	
  cells	
  that	
  
are	
  formed	
  in	
  sheets.	
  
3.  Skeletal	
  muscle	
  cells	
  are	
  
elongated	
  fibers	
  running	
  
the	
  length	
  of	
  the	
  muscle.	
  
1.	
  Cardiac	
  muscle:	
  
•	
  	
  Cardiac	
  muscle	
  is	
  involuntary	
  
muscle.	
  
•  Cardiac	
  muscle	
  is	
  found	
  in	
  the	
  
walls	
  of	
  the	
  heart.	
  
•  Cardiac	
  muscle	
  cells	
  are	
  
highly	
  branched,	
  
interconnected,	
  and	
  bounded	
  
on	
  each	
  end	
  by	
  intercalated	
  
disks.	
  
2.	
  Smooth	
  muscle:	
  
•	
  	
  Smooth	
  muscle	
  is	
  
involuntary	
  muscle	
  without	
  
striaAons.	
  
•  Smooth	
  muscle	
  is	
  also	
  
called	
  visceral	
  muscle	
  
because	
  it	
  lines	
  the	
  walls	
  of	
  
the	
  organs	
  and	
  blood	
  
vessels.	
  	
  	
  
•  Skeletal	
  muscle	
  is	
  
voluntary	
  muscle.	
  
•  Skeletal	
  muscle	
  is	
  
aQached	
  to	
  bones	
  to	
  
facilitate	
  movement.	
  
•  Skeletal	
  muscle	
  cells	
  are	
  
called	
  fibers	
  and	
  are	
  
striated	
  because	
  of	
  the	
  
acAn	
  and	
  myosin	
  bands.	
  	
  	
  	
  
3.	
  Skeletal	
  muscle:	
  
MUSCLE	
  CONTRACTION	
  
Pathway	
  of	
  Muscle	
  Control	
  
Skeletal	
  muscle:	
  AcAn	
  Filaments	
  
•  Skeletal	
  muscle	
  cells	
  called	
  fibers	
  &	
  striated	
  because	
  of	
  acAn	
  and	
  
myosin	
  bands.	
  
•  AcAn	
  filaments	
  consist	
  of	
  two	
  chains	
  of	
  globular	
  acAn	
  monomers	
  
intertwined	
  in	
  a	
  helix.	
  
•  AcAn	
  filaments	
  support	
  the	
  cell	
  and	
  any	
  projecAons,	
  such	
  as	
  
microvilli.	
  
•  AcAn,	
  and	
  another	
  molecule	
  called	
  myosin,	
  are	
  also	
  involved	
  in	
  
muscle	
  contracAon	
  and	
  cell	
  division.	
  
2	
  chains	
  	
  of	
  
globular	
  acAn	
  
monomer	
  
Skeletal	
  Muscle	
  and	
  Physiology	
  
Skeletal	
  Muscle	
  ContracAon	
  
•  In	
  the	
  presence	
  of	
  calcium,	
  myosin	
  
binds	
  to	
  the	
  acAn	
  filaments.	
  
•  The	
  myosin	
  head	
  flexes	
  inward	
  and	
  
backward,	
  causing	
  the	
  acAn	
  filament	
  to	
  
shorten.	
  
•  In	
  the	
  presence	
  of	
  ATP,	
  the	
  myosin	
  
head	
  detaches	
  and	
  then	
  reaQaches	
  at	
  
a	
  new	
  posiAon	
  on	
  the	
  acAn	
  filament.	
  
•  This	
  cycle	
  repeats	
  to	
  conAnue	
  the	
  
shortening	
  of	
  the	
  muscle	
  (contracAon).	
  
Cross-­‐bridge	
  cycle	
  
1.  Acetylcholine	
  (Ach)	
  from	
  a	
  
motor	
  neuron	
  axon	
  terminal	
  
diffuse	
  to	
  the	
  muscle	
  fiber.	
  
2.  Calcium	
  is	
  transported	
  into	
  
the	
  sarcoplasmic	
  reticulum	
  
3.  Presence	
  of	
  calcium	
  triggers	
  
the	
  exposure	
  of	
  myosin	
  
binding	
  sites.	
  
4.  Myosin	
  head	
  binds	
  to	
  actin	
  
filaments	
  
Cross-­‐bridge	
  cycle	
  
5.	
  The	
  power	
  stroke	
  occurs	
  
6.	
  ATP	
  binds	
  to	
  the	
  myosin	
  head	
  
7.	
  ATP	
  is	
  hydrolyzed	
  to	
  ADP	
  +P,	
  
leading	
  to	
  the	
  reenergizing	
  and	
  
repositioning	
  of	
  the	
  head	
  
SKELETAL	
  SYSTEM	
  
Skeletal	
  systems	
  
•  ContracAle	
  force	
  exerted	
  against	
  
some	
  type	
  of	
  skeleton	
  moves	
  the	
  
animal	
  body	
  	
  
•  Many	
  invertebrates	
  have	
  a	
  
hydrostaAc	
  skeleton,	
  which	
  is	
  a	
  
fluid-­‐filled	
  body	
  cavity	
  	
  
•  Others	
  have	
  an	
  exoskeleton	
  of	
  
hardened	
  structures	
  at	
  the	
  body	
  
surface	
  	
  
•  Vertebrates	
  have	
  an	
  endoskeleton,	
  
an	
  internal	
  skeleton	
  of	
  carAlage,	
  
bone,	
  or	
  both	
  
1.  HydrostaAc	
  skeleton	
  
– A	
  confined	
  fluid	
  accepts	
  the	
  force	
  of	
  muscle	
  
contracAon	
  	
  
2.  Exoskeleton	
  	
  
– Consists	
  of	
  hardened	
  parts	
  at	
  the	
  body	
  surface	
  	
  
3.  Endoskeleton	
  
– Consists	
  of	
  hardened	
  parts	
  inside	
  the	
  body	
  
Human	
  skeletal	
  
system	
  
SKULL
cranial bones
facial bones
sternum
RIB CAGE
ribs
VERTEBRAL COLUMN
vertebrae
intervertebral disks
PECTORAL GIRDLES
AND UPPER EXTREMITIES
clavicle
scapula
humerus
radius
ulna
carpals
metacarpals
phalanges
pelvic girdle
femur
patella
tibia
fibula
tarsals
metatarsals
phalanges
PELVIC GIRDLE AND
LOWER EXTREMITIES
MUSCULO-­‐SKELETAL	
  SYSTEM	
  
Muscle-­‐	
  tendon-­‐bones	
  ligaments	
  
1.	
  Muscle	
  	
  
o  Long,	
  cylindrical	
  
cells	
  with	
  mulAple	
  
nuclei	
  
o  Form	
  from	
  groups	
  
of	
  embryonic	
  cells	
  
that	
  fuse	
  before	
  
they	
  differenAate	
  
and	
  mature	
  
o  Bundled	
  inside	
  a	
  
dense	
  connecAve	
  
Assue	
  sheath	
  
2.	
  Tendons	
  	
  
o Extensions	
  of	
  
connecAve	
  Assue	
  
sheath	
  
o AQach	
  skeletal	
  
muscles	
  to	
  bones	
  
3.	
  Joints	
  
•  Joints	
  
– Regions	
  where	
  bones	
  meet	
  
– Most	
  allow	
  bones	
  to	
  move	
  
– Held	
  together	
  by	
  ligaments	
  
•  Types	
  of	
  joints	
  
I.  Fibrous	
  joint	
  
II.  CarAlaginous	
  joint	
  
III.  Synovial	
  joint	
  
•  Muscles	
  generally	
  work	
  in	
  antagonisAc	
  
pairs	
  to	
  provide	
  movement.	
  
•  Muscles	
  arAculate	
  movement	
  at	
  joints.	
  
1.  Synovial	
  joints	
  have	
  a	
  fluid	
  filled	
  
cavity	
  that	
  ease	
  fricAon	
  as	
  the	
  
bones	
  move.	
  
2.  Hinged	
  joints	
  move	
  only	
  in	
  one	
  
direcAon.	
  
3.  Ball-­‐and-­‐socket	
  joints	
  allow	
  for	
  
rotaAonal	
  movement.	
  
Types of joint
Types of synovial joint and location

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Topic 5 Muscular System

  • 1. TOPIC  5:     MUSCULO-­‐SKELETAL  SYSTEM  
  • 2. Learning  outcomes   1.  IdenAfy  types  of  muscle  Assues   2.  Describe  types  of  skeletal  system   3.  IdenAfy  human  skeletal  system   4.  IdenAfy  the  component  of    human  musculo-­‐skeletal  system   5.  Explain  how  muscle  contracts   6.  Describe  muscle  and  bone  relaAonships  
  • 3. topic   1.  Muscle  bone  partnership   2.  Types  of  muscle  Assue   3.  Muscle  contracAon   4.  Skeletal  system   5.  Musculo-­‐skeletal  system  
  • 5. The  muscle–bone  partnership   •  Skeletal  muscles  are  bundles  of  muscle  fibers  that  interact   with  bones  and  with  one  another     •  Tendons  aQach  skeletal  muscles  to  bones   AcAon  of  muscle:   Example:  Movement  of  the  forearm  at  the  elbow  joint   1.  When  muscle  contract  they  shorter   2.  When  muscle  relaxed,  they  longer   3.  Muscle  only  pull;  they  cannot  push.   4.  Both  muscle  work  in  antagonisAc  pairs  
  • 6. Synergy  Muscle   • Some cause movements by working as pairs or groups (synergy) • Synergy muscle assist prime mover
  • 7. Antagonist  Muscle   Others oppose or reverse the action of a partner muscle (antagonist)
  • 8.
  • 9. TYPES  OF  MUSCLE  TISSUE  
  • 10. Muscle  Tissues:  Move  the  Body   •    Muscle  Assues  are  frequently  called   contracAle  Assues  because  they  contain   contracAle  protein  filaments  such  as  acAn  and   myosin.   •  There  are  three  types  of  muscle  Assues.   1.  Skeletal   2.  Cardiac   3.  Smooth  
  • 11. 1.  Skeletal  Muscle   •  There  are  3  types  of  muscle  in  the   human  body,  each  with  a  different   structure.   1.  Cardiac  muscle,  found  in   the  heart,  consists  of   striated,  branched  cells   forming  a  la[ce.   2.   Smooth  muscle  are  long,   spindle-­‐shaped  cells  that   are  formed  in  sheets.   3.  Skeletal  muscle  cells  are   elongated  fibers  running   the  length  of  the  muscle.  
  • 12. 1.  Cardiac  muscle:   •    Cardiac  muscle  is  involuntary   muscle.   •  Cardiac  muscle  is  found  in  the   walls  of  the  heart.   •  Cardiac  muscle  cells  are   highly  branched,   interconnected,  and  bounded   on  each  end  by  intercalated   disks.  
  • 13. 2.  Smooth  muscle:   •    Smooth  muscle  is   involuntary  muscle  without   striaAons.   •  Smooth  muscle  is  also   called  visceral  muscle   because  it  lines  the  walls  of   the  organs  and  blood   vessels.      
  • 14. •  Skeletal  muscle  is   voluntary  muscle.   •  Skeletal  muscle  is   aQached  to  bones  to   facilitate  movement.   •  Skeletal  muscle  cells  are   called  fibers  and  are   striated  because  of  the   acAn  and  myosin  bands.         3.  Skeletal  muscle:  
  • 16. Pathway  of  Muscle  Control  
  • 17. Skeletal  muscle:  AcAn  Filaments   •  Skeletal  muscle  cells  called  fibers  &  striated  because  of  acAn  and   myosin  bands.   •  AcAn  filaments  consist  of  two  chains  of  globular  acAn  monomers   intertwined  in  a  helix.   •  AcAn  filaments  support  the  cell  and  any  projecAons,  such  as   microvilli.   •  AcAn,  and  another  molecule  called  myosin,  are  also  involved  in   muscle  contracAon  and  cell  division.   2  chains    of   globular  acAn   monomer  
  • 18.
  • 19. Skeletal  Muscle  and  Physiology  
  • 20.
  • 21.
  • 22. Skeletal  Muscle  ContracAon   •  In  the  presence  of  calcium,  myosin   binds  to  the  acAn  filaments.   •  The  myosin  head  flexes  inward  and   backward,  causing  the  acAn  filament  to   shorten.   •  In  the  presence  of  ATP,  the  myosin   head  detaches  and  then  reaQaches  at   a  new  posiAon  on  the  acAn  filament.   •  This  cycle  repeats  to  conAnue  the   shortening  of  the  muscle  (contracAon).  
  • 23. Cross-­‐bridge  cycle   1.  Acetylcholine  (Ach)  from  a   motor  neuron  axon  terminal   diffuse  to  the  muscle  fiber.   2.  Calcium  is  transported  into   the  sarcoplasmic  reticulum   3.  Presence  of  calcium  triggers   the  exposure  of  myosin   binding  sites.   4.  Myosin  head  binds  to  actin   filaments  
  • 24. Cross-­‐bridge  cycle   5.  The  power  stroke  occurs   6.  ATP  binds  to  the  myosin  head   7.  ATP  is  hydrolyzed  to  ADP  +P,   leading  to  the  reenergizing  and   repositioning  of  the  head  
  • 26. Skeletal  systems   •  ContracAle  force  exerted  against   some  type  of  skeleton  moves  the   animal  body     •  Many  invertebrates  have  a   hydrostaAc  skeleton,  which  is  a   fluid-­‐filled  body  cavity     •  Others  have  an  exoskeleton  of   hardened  structures  at  the  body   surface     •  Vertebrates  have  an  endoskeleton,   an  internal  skeleton  of  carAlage,   bone,  or  both  
  • 27. 1.  HydrostaAc  skeleton   – A  confined  fluid  accepts  the  force  of  muscle   contracAon     2.  Exoskeleton     – Consists  of  hardened  parts  at  the  body  surface     3.  Endoskeleton   – Consists  of  hardened  parts  inside  the  body  
  • 29. SKULL cranial bones facial bones sternum RIB CAGE ribs VERTEBRAL COLUMN vertebrae intervertebral disks PECTORAL GIRDLES AND UPPER EXTREMITIES clavicle scapula humerus radius ulna carpals metacarpals phalanges pelvic girdle femur patella tibia fibula tarsals metatarsals phalanges PELVIC GIRDLE AND LOWER EXTREMITIES
  • 30. MUSCULO-­‐SKELETAL  SYSTEM   Muscle-­‐  tendon-­‐bones  ligaments  
  • 31. 1.  Muscle     o  Long,  cylindrical   cells  with  mulAple   nuclei   o  Form  from  groups   of  embryonic  cells   that  fuse  before   they  differenAate   and  mature   o  Bundled  inside  a   dense  connecAve   Assue  sheath  
  • 32.
  • 33. 2.  Tendons     o Extensions  of   connecAve  Assue   sheath   o AQach  skeletal   muscles  to  bones  
  • 34. 3.  Joints   •  Joints   – Regions  where  bones  meet   – Most  allow  bones  to  move   – Held  together  by  ligaments   •  Types  of  joints   I.  Fibrous  joint   II.  CarAlaginous  joint   III.  Synovial  joint  
  • 35. •  Muscles  generally  work  in  antagonisAc   pairs  to  provide  movement.   •  Muscles  arAculate  movement  at  joints.   1.  Synovial  joints  have  a  fluid  filled   cavity  that  ease  fricAon  as  the   bones  move.   2.  Hinged  joints  move  only  in  one   direcAon.   3.  Ball-­‐and-­‐socket  joints  allow  for   rotaAonal  movement.  
  • 36.
  • 37.
  • 38.
  • 39.
  • 41. Types of synovial joint and location