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Advanced Organic Chemistry
- 4. The E1 Reaction The alkyl halide dissociate, forming a carbocation The base removes a proton The mechanism shows that an E1 reaction is a two-step reaction
- 7. Energy Diagram for E1
- 8. Transition States Rate = k [A] See SN1 and E1 Reaction Mechanisms And Radical Chain Reaction
- 10. Here are four characteristics that the E1 / SN1 mechanisms have in common.
- 11. Dehydration of Alcohols Acid assisted reactions are always E1
- 12. The E2 Mechanism
- 13. Energy Diagram for the E2 Mechanism
- 14. Transition States Rate = k [A][B] See SN2 and E2 Reaction Mechanisms
- 18. Here are four characteristics that the E2 / SN2 mechanisms have in common.
- 19. Effect of the Substrate on E2 Reactivity
- 20. Bulky leaving groups: Hofmann Elimination This give the anti-Saytzeff product (least substituted product is formed)!
- 26. The Saytzeff) Rule (Z-rule) According to the Z-rule , the major product in a dehydrohalgenation is the most stable product .