This is a presentation file on Inductive Effect, Bond Length, Bond Energy, Bond Angle for the course Organic Pharmacy I, course code is PHAR-1105 specially for the pharmacy students. Also it can be used for the Biochemistry students and other like as HSC level in Bangladesh or another country. We are the students of Mawlana Bhashani Science and Technology University, department of pharmacy which is located in Tangail. Thank you for your patient.

1. WELCOME TO OUR
PRESENTATION
PRESENTED TO
OUR RESPECTABLE TEACHER
DR MD ASHRAF ALI SIR
CHAIRMAN
DEPARTMENT OF PHARMACY
MAWLANA BHASHANI SCIENCE AND TECHNOLOGY UNIVERSITY
TANGAIL 1902, BANGLADESH

2. • Sabbir Ahmed (PHA-19021)
• Belayet Hossain (PHA-19028)
• Taherul Islam (PHA-19032)
Presented by Group (2)
PRESENTATION

3. TOPICS:
1.Inductive Effect
2.Bond Length
3.Bond Energy
4.Bond Angle
Course Name: Organic Pharmacy
Course Code: PHAR-1105

4. INDUCTIVE EFFECT
Inductive effect is defined as permanent displacement of shared election pair in carbon chain
towards more electronegative atom or group.
The inductive effect (I Effect) reffers to the polarity produced in a molecule as a result of higher
electronegativity of one atom compared to another.
Simply we can say,,

5. TYPES OF INDUCTIVE EFFECT
1. Negative Inductive Effect
2. Positive Inductive Effect
Here, we‘ll describe about this classification.
* Negative Inductive Effect (-I) :-
The elections withdrawing nature of groups or atoms is called negative inductive effect.
It is indicated by –I, following are the examples of groups in the decreasing order of their –I
effect:

6. Electronegativeity and inductive effects:
Two principles – electron-withdrawing substituents can increase acidity of a nearby atom, which increases
with electronegativity and decreases with increasing distance to the atom.

7. * Positive Inductive Effect (+I) :-
It reffers to the electron increasing nature of the groups of atoms and is denoted by +I.
The following are the examples of groups in the decreasing order of their +I effect.

8. Graphical charts -

9. +I and –I effect groups:-

10. APPLICATION OF
INDUCTIVE EFFECT
Inductive effect is useful in explaining the strength of some organic acids and bases.
a) Effect is substitute on the acid strength of aliphatic acids.
HCOOH > CH3 COOH > (CH3)2CHCOOH
Reason : acidic strength decreases as +I effect of tge alkyle group increases.
b) O2NCH2COOH > FCH2COOH > ClCH2COOH > BrCH2COOH >ICH2COOH > CH3COOH
Reason : acidic strength decreases as –I effect of the group or halogen decreases.

11. BOND LENGTH
Distances between center of bonded ions are called bond length or bond distance.
Or, when two atoms are bonded by a covalent bond, the distance between the centres of the two nuclei
is called bond length.
Bond length is related to Bond order when more electrons participatesin bond formation the bond will get
shorter.
Bond length are measured by X-ray crystallography and by microwave spectroscopy. The unit of bond
length is Angstrom (1Å = 10-8 cm). For most bonds the values are 1Å to 2Å. Some typical bond length are
given bellow:-

12. Bond length measurement :- Na & Cl atom

13. BOND ENERGY
Bond energy or bond strength is defined as the amount of energy required to break a bond in a molecule.
Bond energyies depend upon the type of bond as well as the structural environment in which the bond is situated. They are determined
by quantitive measurments of heats of chemical reactions and by spectroscopic methods. The unit of bond energy is kcal/mole.

14. Some bond energy list:-

15. BOND ANGLE
• A bond angle is the angle formed between three atoms across at least two bonds
Or,, A bond angle is the angle between two bonds
originating from the same atom in a covalent
species.

16. • Different bond angles →

17. VSEPR table →

18. • Sources
-Organic Chemistry by Bhal & Bhal
-Wikipedia.org
-Sldshare.net

19. THANK
YOU