Antibiotics aminoglycoside and tetracycline

1. AMINOGLYCOSIDE
ANTIBIOTICS
&
TETRACYCLINE
Dr.S.S.RAJENDRAN.,M.Pharm.,Ph.D
N.SANTHI.,M.Pharm.,
RVS COLLEGE OF PHARMACEUTICAL SCIENCES
SULUR, COIMBATORE, TAMILNADU
INDIA-641402

2. ANTIBIOTICS MECHANISM

3. Aminoglycosides

4. Aminoglycosides

5. Aminoglycosides

6. Aminoglycosides

7. TETRACYCLINES

8. Tetracyclines
Tetracycline is an antibiotic which is used in the treatment of infections in the
lungs, reproductive organs, and cholera.

10. Tetracyclines- mechanism action
Tetracycline binds to the 30S
subunit of microbial ribosomes.
it prevents introduction of new
amino acids to the nascent peptide
chain

19. These two unfaourable reactions stimulated the
research that led to the development of the more
stable(not affected by acidic or basic PH) and longer
acting compounds.
6-deoxytetracycline
Methacycline
Doxycycline
Minocycline

22. THANK YOU