Talk about the history (real and imagined) of the Lake Arrowhead Microbial Genomes meeting

1. Arrowhead and Microbial Genomics
Update on the Tree of Life
September 11, 2022
Lake Arrowhead Microbial Genomes
#LAMG2022
Jonathan A. Eisen
University of California, Davis
@phylogenomics
LAMG

2. phylogenomics.blogspot.com

3. LAMG History

4. Organizers

5. LAMG History

6. My Other Life

7. My Other Life
LAMG HISTORY

8. Question for Today
LAMG HISTORY
What Really
Happened to
LAMG2020?
Why was it cancelled?
Was it really
cancelled?
If not, what happened
there?

9. Secret Messages In My Slides
• Been trying for years to warn everyone
about a secret society associated with
LAMG
• Been doing this via slides in my talks
• But seem to be ignored
• So here is a reminder

10. TIGR

11. TIGR
Ambiguous Origin

12. TIGR

13. TIGR

14. TIGR

15. TIGR

16. TIGR

17. TIGR

18. ???????

19. The Tree of Life is Still Angry

20. Blast Peptide
LAKEARROWHEAD

22. Microbiomes and Religion

23. Al Gore Invented the Microbiome

24. Microbiome as Excuse

25. Microbiome and Monogamy

26. Microbiome and Fart Alarms

27. Using the Google

28. Possible Source of Confusion
Jeffrey van Leeuwenhoek Miller

31. Started with a Motorcycle Group

32. One of their members Luis Gort

33. Got in Trouble with the Law

34. Left to Start a Gaming Club

35. LAMG Meeting Try #1
• Leeuwenhoek’s
Animacules Many
Genes meeting
• Nobody came
• Discovered
similarity between
Jeffrey Miller &
Leewenhoek

36. • Many others have been in on the LAMG
conspiracy
• You can tell this from their quotes from
past meetings
Too Many Secrets

37. Too Many Secrets
Leave it to Jeff Miller to take a shot at the
Gordon Conferences in his intro

38. It looks like someone with a bad cold sneezed
against the wall
Too Many Secrets

39. He lied about the size of anthrax
Too Many Secrets

40. If it grows you win, if it doesn’t you have to
give me your soul for all eternity
Too Many Secrets

41. That’s because she has the arrogance of the
aristocrats
Too Many Secrets

42. Space-time continuum of genes and genomes
Too Many Secrets

43. The human mind can conceive of things with
no basis in physical reality
Too Many Secrets

44. Thoughts can go faster than the speed of
light
Too Many Secrets

45. Gene sequences are the wormhole that allows
one to tunnel into the past
Too Many Secrets

46. The human guts are a real milieu
Too Many Secrets

47. Microbes not only have a lot of sex, they have
a lot of weird sex
Too Many Secrets

48. There comes a point in life when you have to
bring chemists into the picture
Too Many Secrets

49. And there's Jeffrey Dahmer
Too Many Secrets

50. There comes a point in life when you have to
bring chemists into the picture
Too Many Secrets

51. The rectal swabs are here in tan color
Too Many Secrets

52. Antibiotics do not kill things, they corrupt
them
Too Many Secrets

53. If I have time I will tell you about a dream
Too Many Secrets

54. I have been influenced by Fisher Price
throughout my life
Too Many Secrets

55. And we will bring out the unused cheese from
yesterday
Too Many Secrets

56. A little bit about time, but I am going to spend
a lot less time on time than on space
Too Many Secrets

57. This is going to be ironic coming from
someone who studies circumcision
Too Many Secrets

58. In an engineering sense, the vagina is a
simple plug flow reactor
Too Many Secrets

59. He wanted to keep his finger in the Chlamydia
stuff
Too Many Secrets

60. It may be sh*t to you but it's my bread and
butter
Too Many Secrets

61. Epigenetics is the ancient aliens of science
Too Many Secrets

62. We were relying on them to poop
Too Many Secrets

63. Here it is again drawn out in an almost
unreadable way
Too Many Secrets

64. This doesn't actually mean anything it is just
cool
Too Many Secrets

65. You are usually not sitting in a room by
yourself — pauses — but maybe you are
Too Many Secrets

66. I am going to show you this dense and
incomprehensible heat map
Too Many Secrets

67. I didn't mean to say that, I really didn’t
Too Many Secrets

68. It is a question for you but a pet peeve of
mine
Too Many Secrets

69. I would like to say gonorrheae kills a ton of
people (but it doesn’t)
Too Many Secrets

70. What we want to do is go snorkeling in the
microbiome
Too Many Secrets

71. Putting this all together what have we
learned? - I like colorful images
Too Many Secrets

72. A paper came out next year
Too Many Secrets

73. So Many Secrets
• Why was the partner meeting to LAMG -
the “ASM Small Genomes Meeting”
cancelled?
• Why is LAMG not written out in full?
• Which Jeffrey Miller really runs the
meeting?
• Why is this meeting near the town of Twin
Peaks?

74. Question for Today
LAMG HISTORY
What Really
Happened to
LAMG2020?
Why was it cancelled?
Was it really
cancelled?
If not, what happened
there?

75. Secret Story of LAMG202
• Early 2019 the organizers started
planning LAMG2020
• I ask you - what could a bunch of experts
in microbial genomics, evolution,
bioinformatics, pathogens, drug
treatments, and animal-microbe
interactions have been up to in 2019 and
early 2020

76. What Do The Have in Common?

77. What Do The Have in Common?
The All Hate Eukaryotes

78. LAMG 2020
• It was going to be a new meeting with a
new name
• To recognize a new group they created -
the “anti karyote society”
• They even refused to use the “eu” in
eukaryote

79. LAMG 2020
• And they planned to meet at Lake
Arrowhead
• And they wanted the meeting to be much
bigger
• So they called it the “Big, Large,
Enormous” meeting

80. LAMG 2020
• Also known as the meeting of the
• Lake Arrowhead Big Large Enormous Anti
Karyote Society

81. LAMG 2020
• Also known as the meeting of the
• Lake Arrowhead Big Large Enormous Anti
Karyote Society

82. Next Meeting?