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! 
! 
Something about the Lake Arrowhead Microbial 
Genomes Meeting 
! 
September 14, 2014 
Lake Arrowhead Microbial Genom...
Lake Arrowhead Microbial Genomes 
Also knows as 
! 
“The Microbial World According to 
Jeffrey Miller”
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
Who is Jeffrey Miller?
History of Lake Arrowhead Microbial Genomes
History of Lake Arrowhead Microbial Genomes
History of Lake Arrowhead Microbial Genomes
History of Lake Arrowhead Microbial Genomes
History of Lake Arrowhead Microbial Genomes
History of Lake Arrowhead Microbial Genomes
History of Lake Arrowhead Microbial Genomes
History of Lake Arrowhead Microbial Genomes
History of Lake Arrowhead Microbial Genomes 
See tinyurl.com/TheRealJeffMiller
Meeting Notes Insightful
1998
1998
1998
1998
1998
1998
1998
1998
1998
1998
1998
1998
1998
1998
1998
1998
2002
2002
2002
2002
2002
2002
2002
2002
2002
2002
2002
2002
2002
2002
2002
Real History of Arrowhead 
QUOTES, QUOTES, QUOTES
Quotes 
• Space-time continuum of genes and 
genomes
Quotes 
• Space-time continuum of genes and 
genomes 
• Microbes not only have a lot of sex, they 
have a lot of weird sex
Quotes 
• Space-time continuum of genes and 
genomes 
• Microbes not only have a lot of sex, they 
have a lot of weird sex...
Quotes 
• Space-time continuum of genes and 
genomes 
• Microbes not only have a lot of sex, they 
have a lot of weird sex...
Quotes 
• Space-time continuum of genes and 
genomes 
• Microbes not only have a lot of sex, they 
have a lot of weird sex...
Quotes 
• Space-time continuum of genes and 
genomes 
• Microbes not only have a lot of sex, they 
have a lot of weird sex...
Quotes 
• There comes a point in life when you have 
to bring chemists into the picture
Quotes 
• There comes a point in life when you have 
to bring chemists into the picture 
• The rectal swabs are here in ta...
Quotes 
• There comes a point in life when you have 
to bring chemists into the picture 
• The rectal swabs are here in ta...
Quotes 
• There comes a point in life when you have 
to bring chemists into the picture 
• The rectal swabs are here in ta...
Quotes 
• There comes a point in life when you have 
to bring chemists into the picture 
• The rectal swabs are here in ta...
Quotes 
• There comes a point in life when you have 
to bring chemists into the picture 
• The rectal swabs are here in ta...
Quotes 
• And we will bring out the unused cheese 
from yesterday
Quotes 
• And we will bring out the unused cheese 
from yesterday 
• A paper came out next year
Quotes 
• And we will bring out the unused cheese 
from yesterday 
• A paper came out next year 
• It takes 1000 nanobiolo...
Quotes 
• And we will bring out the unused cheese 
from yesterday 
• A paper came out next year 
• It takes 1000 nanobiolo...
Quotes 
• And we will bring out the unused cheese 
from yesterday 
• A paper came out next year 
• It takes 1000 nanobiolo...
Quotes 
• And we will bring out the unused cheese 
from yesterday 
• A paper came out next year 
• It takes 1000 nanobiolo...
Quotes 
• We are the environment. We live the 
phenotype.
Quotes 
• We are the environment. We live the 
phenotype. 
• We have been using this word for many 
years without actually...
Quotes 
• We are the environment. We live the 
phenotype. 
• We have been using this word for many 
years without actually...
Quotes 
• We are the environment. We live the 
phenotype. 
• We have been using this word for many 
years without actually...
Evolution of Lake Arrowhead
Blast Peptide
Homework 
• Do blastp search with other famous people 
associated with Lake Arrowhead Meeting 
• JEFFREYHMILLER 
• JEFFREY...
Trends in Topics
History of Lake Arrowhead Microbial Genomes 
See tinyurl.com/TheRealJeffMiller
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Topics Over Time 
100 
75 
50 
25 
0 
Genomes Communities 
Metagenomes Microbiomes 
1998 2000 2002 2004 2006 2008 2010 201...
Possible Talks for 2016?
Microbiomes and Religion
Al Gore Invented the Microbiome
Microbiome as Excuse
Probiotics for Toilets
Microbiome and Doping
Microbiome and Doping
Microbiome and Doping
Microbiome Diet
Microbiome and Monogamy
Microbiome and Monogamy
Microbiome and Monogamy
Microbiome and Monogamy
Microbiome and Fart Alarms
Microbiome and Fart Alarms
Microbiome and Fart Alarms
Microbiome Intelligent Design
Microbiome and .. well …
Microbiome and .. well …
Microbiome and .. well …
Possible Talks for 2018?
Microbiome Will GIVE The Talks
Jonathan Eisen - History of Lake Arrowhead Microbial Genomes meeting #LAMG14
Jonathan Eisen - History of Lake Arrowhead Microbial Genomes meeting #LAMG14
Jonathan Eisen - History of Lake Arrowhead Microbial Genomes meeting #LAMG14
Jonathan Eisen - History of Lake Arrowhead Microbial Genomes meeting #LAMG14
Jonathan Eisen - History of Lake Arrowhead Microbial Genomes meeting #LAMG14
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Jonathan Eisen - History of Lake Arrowhead Microbial Genomes meeting #LAMG14

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Jonathan Eisen - History of Lake Arrowhead Microbial Genomes meeting #LAMG14

  1. 1. ! ! Something about the Lake Arrowhead Microbial Genomes Meeting ! September 14, 2014 Lake Arrowhead Microbial Genomes #LAMG14 ! Jonathan A. Eisen University of California, Davis @phylogenomics
  2. 2. Lake Arrowhead Microbial Genomes Also knows as ! “The Microbial World According to Jeffrey Miller”
  3. 3. Who is Jeffrey Miller?
  4. 4. Who is Jeffrey Miller?
  5. 5. Who is Jeffrey Miller?
  6. 6. Who is Jeffrey Miller?
  7. 7. Who is Jeffrey Miller?
  8. 8. Who is Jeffrey Miller?
  9. 9. Who is Jeffrey Miller?
  10. 10. Who is Jeffrey Miller?
  11. 11. Who is Jeffrey Miller?
  12. 12. Who is Jeffrey Miller?
  13. 13. Who is Jeffrey Miller?
  14. 14. Who is Jeffrey Miller?
  15. 15. History of Lake Arrowhead Microbial Genomes
  16. 16. History of Lake Arrowhead Microbial Genomes
  17. 17. History of Lake Arrowhead Microbial Genomes
  18. 18. History of Lake Arrowhead Microbial Genomes
  19. 19. History of Lake Arrowhead Microbial Genomes
  20. 20. History of Lake Arrowhead Microbial Genomes
  21. 21. History of Lake Arrowhead Microbial Genomes
  22. 22. History of Lake Arrowhead Microbial Genomes
  23. 23. History of Lake Arrowhead Microbial Genomes See tinyurl.com/TheRealJeffMiller
  24. 24. Meeting Notes Insightful
  25. 25. 1998
  26. 26. 1998
  27. 27. 1998
  28. 28. 1998
  29. 29. 1998
  30. 30. 1998
  31. 31. 1998
  32. 32. 1998
  33. 33. 1998
  34. 34. 1998
  35. 35. 1998
  36. 36. 1998
  37. 37. 1998
  38. 38. 1998
  39. 39. 1998
  40. 40. 1998
  41. 41. 2002
  42. 42. 2002
  43. 43. 2002
  44. 44. 2002
  45. 45. 2002
  46. 46. 2002
  47. 47. 2002
  48. 48. 2002
  49. 49. 2002
  50. 50. 2002
  51. 51. 2002
  52. 52. 2002
  53. 53. 2002
  54. 54. 2002
  55. 55. 2002
  56. 56. Real History of Arrowhead QUOTES, QUOTES, QUOTES
  57. 57. Quotes • Space-time continuum of genes and genomes
  58. 58. Quotes • Space-time continuum of genes and genomes • Microbes not only have a lot of sex, they have a lot of weird sex
  59. 59. Quotes • Space-time continuum of genes and genomes • Microbes not only have a lot of sex, they have a lot of weird sex • Gene sequences are the wormhole that allows one to tunnel into the past
  60. 60. Quotes • Space-time continuum of genes and genomes • Microbes not only have a lot of sex, they have a lot of weird sex • Gene sequences are the wormhole that allows one to tunnel into the past • This is how you do metagenomics on 50 dollars, and that’s Canadian dollars
  61. 61. Quotes • Space-time continuum of genes and genomes • Microbes not only have a lot of sex, they have a lot of weird sex • Gene sequences are the wormhole that allows one to tunnel into the past • This is how you do metagenomics on 50 dollars, and that’s Canadian dollars • The human guts are a real milieu of stuff
  62. 62. Quotes • Space-time continuum of genes and genomes • Microbes not only have a lot of sex, they have a lot of weird sex • Gene sequences are the wormhole that allows one to tunnel into the past • This is how you do metagenomics on 50 dollars, and that’s Canadian dollars • The human guts are a real milieu of stuff • Antibiotics do not kill things, they corrupt them
  63. 63. Quotes • There comes a point in life when you have to bring chemists into the picture
  64. 64. Quotes • There comes a point in life when you have to bring chemists into the picture • The rectal swabs are here in tan color
  65. 65. Quotes • There comes a point in life when you have to bring chemists into the picture • The rectal swabs are here in tan color • If I have time I will tell you about a dream
  66. 66. Quotes • There comes a point in life when you have to bring chemists into the picture • The rectal swabs are here in tan color • If I have time I will tell you about a dream • Another thing you need to know" pause "Actually you don't NEED to know any of this
  67. 67. Quotes • There comes a point in life when you have to bring chemists into the picture • The rectal swabs are here in tan color • If I have time I will tell you about a dream • Another thing you need to know" pause "Actually you don't NEED to know any of this • I have been influenced by Fisher Price throughout my life
  68. 68. Quotes • There comes a point in life when you have to bring chemists into the picture • The rectal swabs are here in tan color • If I have time I will tell you about a dream • Another thing you need to know" pause "Actually you don't NEED to know any of this • I have been influenced by Fisher Price throughout my life • This is going to be ironic coming from someone who studies circumcision
  69. 69. Quotes • And we will bring out the unused cheese from yesterday
  70. 70. Quotes • And we will bring out the unused cheese from yesterday • A paper came out next year
  71. 71. Quotes • And we will bring out the unused cheese from yesterday • A paper came out next year • It takes 1000 nanobiologists to make one microbiologist
  72. 72. Quotes • And we will bring out the unused cheese from yesterday • A paper came out next year • It takes 1000 nanobiologists to make one microbiologist • In an engineering sense, the vagina is a simple plug flow reactor
  73. 73. Quotes • And we will bring out the unused cheese from yesterday • A paper came out next year • It takes 1000 nanobiologists to make one microbiologist • In an engineering sense, the vagina is a simple plug flow reactor • The human mind can conceive of things with no basis in physical reality
  74. 74. Quotes • And we will bring out the unused cheese from yesterday • A paper came out next year • It takes 1000 nanobiologists to make one microbiologist • In an engineering sense, the vagina is a simple plug flow reactor • The human mind can conceive of things with no basis in physical reality • Thoughts can go faster than the speed of light
  75. 75. Quotes • We are the environment. We live the phenotype.
  76. 76. Quotes • We are the environment. We live the phenotype. • We have been using this word for many years without actually realizing it was correct
  77. 77. Quotes • We are the environment. We live the phenotype. • We have been using this word for many years without actually realizing it was correct • A little bit about time, but I am going to spend a lot less time on time than on space
  78. 78. Quotes • We are the environment. We live the phenotype. • We have been using this word for many years without actually realizing it was correct • A little bit about time, but I am going to spend a lot less time on time than on space • I am going to wrap up as I hear the crickets chirping
  79. 79. Evolution of Lake Arrowhead
  80. 80. Blast Peptide
  81. 81. Homework • Do blastp search with other famous people associated with Lake Arrowhead Meeting • JEFFREYHMILLER • JEFFREYFMILLER • see http://phylogenomics.blogspot.com/2008/09/ tracing-evolutionary-history-of-sarah.html
  82. 82. Trends in Topics
  83. 83. History of Lake Arrowhead Microbial Genomes See tinyurl.com/TheRealJeffMiller
  84. 84. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  85. 85. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  86. 86. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  87. 87. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  88. 88. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  89. 89. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  90. 90. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  91. 91. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  92. 92. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  93. 93. Topics Over Time 100 75 50 25 0 Genomes Communities Metagenomes Microbiomes 1998 2000 2002 2004 2006 2008 2010 2012 2014 2016
  94. 94. Possible Talks for 2016?
  95. 95. Microbiomes and Religion
  96. 96. Al Gore Invented the Microbiome
  97. 97. Microbiome as Excuse
  98. 98. Probiotics for Toilets
  99. 99. Microbiome and Doping
  100. 100. Microbiome and Doping
  101. 101. Microbiome and Doping
  102. 102. Microbiome Diet
  103. 103. Microbiome and Monogamy
  104. 104. Microbiome and Monogamy
  105. 105. Microbiome and Monogamy
  106. 106. Microbiome and Monogamy
  107. 107. Microbiome and Fart Alarms
  108. 108. Microbiome and Fart Alarms
  109. 109. Microbiome and Fart Alarms
  110. 110. Microbiome Intelligent Design
  111. 111. Microbiome and .. well …
  112. 112. Microbiome and .. well …
  113. 113. Microbiome and .. well …
  114. 114. Possible Talks for 2018?
  115. 115. Microbiome Will GIVE The Talks

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