What is Tranquillizer? Classification of Tranquilizer.

1. TRANQUILLIZERS
NIDHI SHARMA

2. INTRODUCTION-
• It act on CNS.
• Sometimes they make people and animal sleepy.
• These drugs are depressants because they suppress the CNS & slow
the body down.
• They are used to treat mental illness that are characteristic of the
psychosis which is a behavioural disorder.
• These are the drug that reduce- Anxiety, Fear, Tension, Agitation,
Related state of Mental Disturbances

3. Contt….
• Tranquilizer term, was brought into existence by F.F. Yonkman
(1953), from the conclusions of investigative studies using the
drug Reserpine, showed the drug had a calming effect on all animals it
was administered to.
• Reserpine, is a Centrally Acting Rauwolfia Alkaloid.The word directly
refers to the state of tranquility in a person and other animals.
• The term is thought to belong to a lexicon of words thought popular or
so-called common, and so is therefore accordingly thought as not
generally in use within the field of medicine, specifically in reference
to the group of medications known as anti-psychotic or neuroleptics.
They are of Two types-
1. Minor Tranquillizers- usually refer to Anxiolytics.
2. Major Tranquillizers- refers to as Antipsychotics

4. CLASSIFICATION-
• FIRST GENERATION-
1. Phenothiazine derivatives-
a) Triflupromazine
b) Thioridazine
c) Mesoridazine
d) Chlorpromazine HCl
Chlorpromazine Triflupromazine

5. Thioridazine a) Mesoridazine
2. Butyrophenones-
a) Haloperidol
b) Droperidol
c) Resoperidone
Haloperidol Droperidol

6. Resoperidone
3. Thioxanthenes-
a) Flupenthixol
b) Clopenthixol
c) Zuclopenthixol
Clopenthixol
Zuclopenthixol

7. SECOND GENERATION-
a) Zotepine
b) Risperidone
c) Clozapine
d) Olanzapine
Zotepine Risperidone
Clozapine
Olanzapine

8. THANK YOU