AMOXICILLIN AND METHOTREXATE DRUGS For nursing students

1. AMOXICILLIN
BY DIVYANG DAMOR
S.Y.BSC (N)

3.  Class of drug:- Beta-lactum Antibiotic
 Route :- Orally
 Dose :- CHILD- 400 mg/day(tab)
ADULT-1600 mg/day(tab)

4. MECHANISM OF ACTION
Amoxicillin is similar to penicillin in it’s
bacterial action against susceptible bacteria
during the stage of active multiplication.
It acts through the inhibition of cell wall
biosynthesis that leads to the death of
bacteria.

5. INDICATION
 To treat bacterial infection,such as chest infection and dental
abscesses.
 Ear infection
 Stomach ulcer (together with clarithromycin)
 Intestinal infection
 Urinary tract infection
 Bone & joint infection

6. CONTRAINDICATIONS
Patient with a known serious
hypersensitivity reaction to other beta
lactens.
Patient with allergies,asthma,hay fever.

7. SIDE EFFECTS
Stomach pain
Black,tarry stool
Loosening of skin
Blood in urine(hematuria)
Chest pain

8. NURSING RESPONSIBILITY
Monitor signs of allergic reactions and
anaphylaxis, including pulmonary
symptoms (tightness in the throat and
chest, wheezing, cough dyspnea) or skin
reactions (rash, pruritus, urticaria).
Notify physician or nursing staff
immediately if these reactions occur.

9. METHOTREXATE

12. INDICATION
Chori carcinoma
Autoimmune disease
Crohn’s disease
Rheumatoid arthritis

13. CONTRAINDICATIONS
Liver disease
Pregnant women
Recent vaccination, especially live vaccine
Hypersensitivity

14. SIDE EFFECTS
Bone marrow suppression
Alopecia
Diarrhoea
Hyperuricemia
Secondary cancer

15. NURSING RESPONSIBILITY
Explain adverse side effects, such as nausea
and vomitin.
Effects of therapy, such as increased
abdominal pain.
The importance of communicating any
physical changes to the health care team.