The G_1, S, and G_2 phases of the cell cycle are collectively known as which part of the cell cycle? Considering mitosis, cytokinesis, and interphase, in which one is nuclear DNA duplicated? When in the cell cycle do chromosomes first split apart? The division of the cytoplasm occurs in what part of the cell cycle? Describe the four phases of nuclear (mitotic) division and what occurs during those phases. Solution 10) Interphase is the phase with G1 , S and G2 cycles. The cell spends most of its time in interphase. The phases are - 11) Nuclear DNA is duplicated in interphase S cycle. 12) Chromosomes split apart in mitosis in metaphase and anaphase. 13) The 4 phases of mitosis are Prophase, metaphase , anaphase and telophase. In prophase cells start break down some structures and build others. In metaphase, the chromosomes with the spindle apparatus line the chromosomes in the middle and form metaphase plate. In anaphase, the sister chromatids pull the chromatids towards opposite poles. In telophase, is the reversal of prophase..