Biomarkers omics 1

1. OmicsOmics TechnologyTechnology
By
Mohammed Z. Naji

2. Contents
 Introduction –Introduction –
What is OMICS technology?What is OMICS technology?
 History of OmicsHistory of Omics
 Omes and OmicsOmes and Omics
 Types of OmicsTypes of Omics

3. Introduction
The complete sequencing of theThe complete sequencing of the
human genome has ushered in ahuman genome has ushered in a
new era of systems biologynew era of systems biology
referred to asreferred to as Omics technologyOmics technology..

4. Introduction
The term ‘‘omic’’ is derived from the
Latin suffix ‘‘ome’’ meaning mass or
many. Thus, OMICS involve a mass
(large number) of measurements per
endpoint.
In biological context , suffix –omics is
used to refer to the study of large sets
of biological molecules

5. The term omics refers to theThe term omics refers to the
comprehensive analysis ofcomprehensive analysis of
biological systemsbiological systems that focusesthat focuses
on complex systems of life.on complex systems of life.
Omics technology mostly done by
softwares

6. History of OmicsHistory of Omics
The first genome was completely
sequenced by Sanger in Cambridge,
UK, in the 1970s. Genome is the
most fundamental part of many
omics.
The word genomics is said to be
appeared in the 1980s and became
widely used in the 1990s.

7. Omes & Omics
The wordThe word ’omics’’omics’ refers to arefers to a
field of studyfield of study in biology endingin biology ending
in the suffixin the suffix -omics-omics such assuch as
genomics, metabolomics, orgenomics, metabolomics, or
proteomics.proteomics.

8. The relatedThe related omeome addressesaddresses
the objects of studythe objects of study of suchof such
fields, such as the genome,fields, such as the genome,
metabolome, or proteomemetabolome, or proteome
respectively.respectively.

9. Main Types of OMICS
OMICS technologies :
 Genomics
 Transcriptomics
 Proteomics
 Metabolomics

11.  Glycome & Glycomics
 Immunolome & Immunolomics
 Lipidome & Lipidomics
 Lipoproteome & Lipoproteomics
 Cellome & Cellomics
 Antibodyome & Antibodyomics
 Diseaseome & Diseaseomics
 Epigenome & Epigenomics
 Foodome &Foodomics
Other Types of OMICS ….

17. Software of DatabaseSoftware of Database

19. 19
(http://www.ebi.ac.uk/fasta33/)(http://www.ebi.ac.uk/fasta33/)
(http://pir.georgetown.edu/pirwww/search/fasta.html)(http://pir.georgetown.edu/pirwww/search/fasta.html)

20. A BLASTA BLAST
ResultResult

21. 21
(Radial Tree)(Radial Tree)
(Phylogram)(Phylogram)

22. 22
(http://www.sanger.ac.uk/Software/Pfam/search.shtml(http://www.sanger.ac.uk/Software/Pfam/search.shtml
))
(http://smart.em(http://smart.em
bl-bl-
heidelberg.de)heidelberg.de)

23. 23
Human and Mouse TranscriptomeHuman and Mouse Transcriptome
http://expression.gnf.org/cgi-bin/index.cgi)http://expression.gnf.org/cgi-bin/index.cgi)
(http://genome-www. stanford.edu/serum/)(http://genome-www. stanford.edu/serum/)

24. Do you think the OMICSDo you think the OMICS
Techniques reach to the space?Techniques reach to the space?