BASICS OF BIOINFORMATICS Bioinformatics is an interdisciplinary field which collects, classify, stores and analyse biological problems using computational technology. Different kinds of databases are developed to store biological information. Several sorts of omics technologies are developed to measure the macromolecules like DNA, RNA, protein and metabolites etc.

1. BASICS OF
BIOINFORMATICS

3. Bioinformatics is the application of computational technology to
handle the rapidly growing repository of information related to
molecular biology.

4. Margaret Dayhoff
The women behind the
origin of Bioinformatics.
In 1965, Dayhoff first
published her collection
of the 65 known
proteins in the Atlas of
Protein Sequence and
Structure.

5. OMICS

6. OMICS - GENOMICS
Genomics, study of the
structure, function, and
inheritance of the genome
(entire set of genetic
material) of an organism.

7. TRANSCRIPTOMICS
The study of transcriptome encoded by the genome of a specific cell or
organism at a specific time.

8. PROTEOMICS
Proteomics is the large-scale
study of proteomes. A proteome
is a set of proteins produced in
an organism, system, or
biological context.

9. METABOLOMICS
Metabolomics, which
is defined as the
comprehensive
analysis of metabolites
in a biological
specimen, is an
emerging technology
that holds promise to
inform the practice of
precision medicine.

10. LIPIDOMICS
Lipidomics is the study of the
structure and function of the
complete set of lipids (the
lipidome) produced in a given
cell or organism as well as their
interactions with other lipids,
proteins and metabolites.

11. GLYCOMICS
Glycomics is a broad and emerging scientific discipline focused on defining the structures and
functional roles of glycans in biological systems.

12. PRIMARY DATABASES

13. NCBI

14. GenBank

15. ENSEMBL

16. ARRAY EXPRESS

17. TCGA

18. GENE PREDICTION TOOL – ORF FINDER

19. EMBL

20. DDBJ

21. UNIPROT

22. PIR

23. SECONDARY DATABASES

24. PROSITE

25. PRINTS DATABASE

26. WHOLE GENOME SHOT GUN SQUENCING

27. DNA MICROARRAY

28. BLAST

29. FASTA

30. CLUSTAL W

31. CONCLUSION
The session was described about the fundamentals of bioinformatics
which include the history, various kinds of databases like primary and
secondary, database searching – BLAST & FASTA, sequencing technique,
gene expression analysis, gene prediction tool and omics in
bioinformatics.