Histology of Epithelium - Dr Muhammad Ali Rabbani - Medicose Academics
Diseases caused by yeast.pdf
1. Diseases caused by yeast
Yeast are round oval unicellular fungi
which reproduced by budding
Candida albicans is responsible for 90% of
infection in human
6. Culture
aerobic easy cultivate need antibiotic
chloramphenicol for primary cultivation
incubation at 37 c for 48 hours
ordinary agar or blood agar
colonies appears around antibiotic discs
which inhibit bacteria growth
7. Creamy to white in color
the yeast are predonately Y
forms but M forms develop in
older cultures
8. Identification
Germ tubes grow in serum for 3hours at
37cmake wet film examine for formation of
filamentous outgrowth germ tube
12. Choronic mucocutaneous candidiasis
Chronic mucocutaneous
candidiasis is persistent or
recurrent candida infection due to
inherited T-cell defects.
Autoimmune and endocrine
disorders may develop in its
recessive form. Diagnosis is based
on recurrent, unexplained
candida infections. Treatment
includes antifungal drugs and
treatment of any endocrine and
autoimmune disorders.
13. Deep infection
involve lower respiratory tract
urinary tract septicemia
localized in eye
endocardium meningitis
kidney bone
18. Systemic infection
require intravenous amphotericin B combined
with flouorocytosin
oral administration of new imidazole
fluconazole may be effective in superficial and
systemic infection