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SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732
Akhouri et al., 2020
DOI: 10.21276/SSR-IIJLS.2020.6.5.2
Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2652
Impact of Acceptance and Mindfulness-Based Intervention as an
Add-on Treatment for Skin Diseases-Acne, Eczema and Psoriasis
Deoshree Akhouri1*
, Maria Madiha2
, Mohammad Akram3
1
Sr. Assistant Professor, Department of Psychiatry, Jawaharlal Nehru Medical College & Hospital, Aligarh Muslim
University, Aligarh, Uttar Pradesh, India
2
PhD Scholar, Department of Psychiatry, Jawaharlal Nehru Medical College & Hospital, Aligarh Muslim University,
Aligarh, Uttar Pradesh, India
3
Associate Professor, Department of Radiotherapy, Jawaharlal Nehru Medical College & Hospital, Aligarh Muslim
University, Aligarh, Uttar Pradesh, India
*Address for Correspondence: Dr. Deoshree Akhouri, Sr. Assistant Professor, Department of Psychiatry, Jawaharlal
Nehru Medical College & Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India
E-mail: drdeoshreeakhouri@gmail.com
Received: 15 Mar 2020/ Revised: 30 May 2020/ Accepted: 24 Aug 2020
ABSTRACT
Background: According to the Global Burden of diseases, there are approximately 15 different types of skin diseases, such as acne,
eczema, psoriasis, impetigo, abscess, etc. It was also noticed that acne, eczema and psoriasis are the topmost skin diseases
prevalent worldwide. Although it is just the physical aspect mostly affected by skin conditions, the sufferer's psychological well-
being is also affected. Various psychotherapies have been adopted to tackle the psychological aspects related to skin diseases.
Acceptance and Mindfulness-Based interventions have proven to be effective for various conditions. The present study was
planned to see the effect of Acceptance and Mindfulness on the treatment of psychological aspects related to the skin condition
of adolescence.
Methods: According to inclusion and exclusion criteria, 45 patients referred from Dermatology and Radiotherapy OPD was
selected for psychosocial management. Different psychological tools were used for assessment purpose. Patients were divided
into 2 groups: experimental and waitlist group. The experimental group was given therapy for 1 ½ month (6 sessions; weekly) and
waitlist group was only on the prescribed medication by Dermatology OPD. Waitlist group was given therapy after the
experimental group's therapy was terminated. Pre and post assessment was done to see the effect of acceptance and mindfulness
intervention.
Results: After 6 sessions of mindfulness, the experiment group improved significantly in all psychosocial dimensions in comparison
to the waitlist group. The significant difference in the level of mindfulness was also found among both experimental and waitlist
group.
Conclusion: Acceptance and mindfulness-based therapy is an effective, non-pharmacological approach towards treatment of
psychosocial aspects related to skin conditions.
Key-words: Acne, Eczema, Acceptance and mindfulness, Adolescents, Skin condition
INTRODUCTION
According to the Global Burden of Diseases (GBD), there
are approximately 15 different types of skin diseases,
such as acne, eczema, psoriasis, impetigo, abscess, etc.
How to cite this article
Akhouri D, Madiha M, Akram M. Impact of Acceptance and
Mindfulness-Based Intervention as an Add-on Treatment for Skin
Diseases-Acne, Eczema and Psoriasis. SSR Inst. Int. J. Life Sci., 2020;
6(5): 2652-2659.
Access this article online
https://iijls.com/
It was also noticed that acne, eczema and psoriasis are
the topmost skin diseases prevalent worldwide [1]
. About
30-70% of individuals at present are suffering from skin
diseases [2-4]
.
According to Frost and Sullivan's report of 2015, about
10-12% of the Indian population suffers from skin
diseases like eczema and psoriasis, are majorly caused by
pollution, global warming, ultraviolet rays, etc [5]
.
Although it is just the physical aspect mostly affected by
skin conditions, the sufferer’s psychological well-being is
also affected. Psychodermatology is an emerging
discipline that addresses the importance of psychological
Research Article
SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732
Akhouri et al., 2020
DOI: 10.21276/SSR-IIJLS.2020.6.5.2
Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2653
intervention in the treatment of dermatological
conditions. The non-pharmacological treatment along
with medication has proven to be quite effective [6,7]
.
Various psychotherapies have been adopted to tackle
the psychological aspects related to skin diseases.
Skin diseases cause a great amount of stress, anxiety,
depression, etc. reducing the quality of life [8]
. Along with
hormonal changes encountered during puberty, skin
conditions are also a part of that phase. The reduced
level of confidence, increased negative self-image,
anxiety, etc. could hinder in their proper psychological
well-being. To address the impact of skin diseases on an
individual's psychology, Acceptance and Mindfulness-
Based Interventions (AMBI) has been adopted.
Various studies have been conducted on acceptance and
mindfulness-based intervention, which was later termed
as “third wave” or generation of cognitive behaviour
therapy (CBT) [9-11]
. Therefore, to overcome the
challenges faced by adolescents, this study focuses its
attention on the impact of acceptance and mindfulness-
based intervention for the treatment of skin conditions
of adolescents.
MATERIALS AND METHODS
Sample Collection- The study was undertaken from
September 2018 to November 2018 in the Department
of Psychiatry, Dermatology and Radiotherapy, Jawaharlal
Nehru Medical College & Hospital, Aligarh Muslim
University, Aligarh, UP, India.
Referred patients diagnosed with acne, eczema and
psoriasis were taken for the study. Total of 45 patients
meeting the inclusion and exclusion criteria of the study
were retained.
Inclusion Criteria
 Adolescents of 13-19 years of age
 Both literate and illiterates were taken
 Both genders were considered
 Diagnosed skin disease-acne, eczema and psoriasis
 Adolescents having reduced level of hopelessness,
optimism, self-esteem, self-efficacy
 Adolescents having a reduced level of mindfulness
 Only the referred cases were taken
 Guardians of adolescents, who gave written
informed consent for the study
Exclusion Criteria
 Adolescents not falling under the age range
 Adolescents having severe forms of psychiatric and
medical conditions
 Adolescents with high hopefulness, optimism, self-
esteem, self-efficacy
 Adolescents having an increased level of mindfulness
 Those, who was not referred
 Who, did not give written informed consent
Tools used
1) Socio-Demographic and Clinical Data Sheet-
Participant's details concerning their clinical and
personal information was collected using semi-
structured clinical and personal datasheet.
2) General Health Questionnaire-12- It was used to
assess the general mental health of individuals [12]
.
3) Beck Hopelessness Scale: It was developed by Aaron
Beck and was a 20 items scale. Scores 0-3 was none
or minimal hopelessness, 4-8 was Mild, 9-14 was
Moderate and 15+ was severe [13]
.
4) Life Orientation Test-Revised (LOT-R)- A 10-item
measure of optimism versus pessimism. Of the 10
items, 3 items measure optimism, 3 items measure
pessimism, and 4 items serve as fillers. Respondents
rate each item on a 4-point scale: 0= strongly
disagree, 1 = disagree, 2 = neutral, 3 = agree, and 4 =
strongly agree. LOT-R is a revised version of the
original LOT. The original LOT had 12 items: 4
worded positively, 4 worded negatively, and 4 fillers
[14]
.
5) General Self-Efficacy (GSE)- This scale was
developed by Jerusalem and Schwarzer. He first
developed originally the German version of this scale
as 20-items and later he translated this scale into
German to English and reduced 10-items. After a
short period, Sud (2002) also translated this scale
from English to Hindi version. Therefore, general
self-efficacy scale (Hindi version) consists of 10-items
rated on a four-point rating scale with the response
categories i.e. (1) Not at all true, (2) Hardly true, (3)
Moderately true, and (4) Exactly true. For scoring, all
the ten items are added to yield the final composite
score with a range from 10-40. The reliability
coefficient of the scale was found to be ranging from
0.76 to 0.90 [15]
.
6) Rosenberg Self-Esteem Scale- It was a 10-item scale
that measures global self-worth by measuring both
positive and negative feelings about the self. The
scale is believed to be uni-dimensional.
SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732
Akhouri et al., 2020
DOI: 10.21276/SSR-IIJLS.2020.6.5.2
Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2654
All items are answered using a 4-point Likert scale
format ranging from strongly agree to strongly
disagree [16]
.
7) Adolescent Psychological Resilience Scale- This scale
consists of 29 items, to be rated on 4 point rating. It
assesses 6-factors, i.e. family support, confidant-
friend support, school support, adjustment, sense of
struggle and empathy [17]
.
8) Five Facet Mindfulness Questionnaire (FFMQ)- It
was a 15 items scale, with the 5-point rating. The
higher the score, the higher is the mindfulness [18]
.
Procedure- Total of 45 patients suffering from acne,
eczema and psoriasis were referred from Dermatology
OPD for psychological management (therefore, no ethics
committee was held for this specifically). Patients with
severe eczema and psoriasis were also referred from the
Department of the Radiotherapy after ruling out cancer.
Since the participants were minors, their written
informed consent was obtained from their parents or
guardians. After obtaining permission, detailed
assessment was done using above mentioned tools; they
were also explained about the purpose of the study and
the amount of time it will require, i.e. 6 weeks (weekly
session). These 45 participants were then randomly
divided into an experimental group and waitlist group.
The experimental group consisted of 23 participants and
waitlist group consisted of 22 participants. The
experimental group was given acceptance and
mindfulness-based intervention along with medication,
whereas the waitlist group was the one who did not
receive any kind of psychological intervention; they were
only on medication prescribed by the Dermatology OPD.
The waitlist group was informed that they will be given
psychological intervention after 1½ months.
The intervention was given in Psychological research lab
of the psychiatry department, JNMC&H, AMU, up to 6
sessions for the next 11/2
months, asking them to visit
weekly.
For patients in the waitlist group, only pre and post-
assessment were done for the next 11/2
months. They
were given TAU. After completion of therapy, the above-
mentioned scales were reassessed to see the effect of
acceptance and mindfulness-based intervention
(Experimental and Waitlist). The level of mindfulness was
assessed immediately after every session (only the
experimental group). Patients in the waitlist group were
given psychological intervention after the termination of
the experimental group’s therapy.
Statistical Analysis- The statistical analysis was done
using the Jeffreys's Amazing Statistics Program (JASP) [19]
.
Percentage (%) is used to see the proportionate part of
the total sample (socio-demographic and clinical data).
the t-test is used to compare between both the groups
to see the effect of acceptance and mindfulness
intervention on psychosocial factors after pre and post-
intervention.
Ethical approval details- The patients were referred
from the Department of Dermatology and Radiotherapy
for Psychosocial Management to Psychiatry OPD. The
intervention was carried out in the Departmental of the
research lab.
RESULTS
Fig. 1 shows the socio-demographic as well as clinical
details of experimental and waitlist group. Most of the
adolescents in both groups were females (Experimental=
69%; Waitlist= 72%), falling under the age range of 13-
17. Maximum adolescents were high-school students
(Experimental= 56%; Waitlist= 54%). Maximum patients
were from middle class (Experimental= 52%; Waitlist=
50%), residing in urban area (Experimental= 69%;
Waitlist= 64%). Most of the patients were receiving
treatment for the past for more than 6 months
(Experimental= 56%; Waitlist= 54%).
SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732
Akhouri et al., 2020
DOI: 10.21276/SSR-IIJLS.2020.6.5.2
Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2655
Fig. 1: shows socio-demographic and clinical details of all the participants
Table 1 shows the difference between scores of
experimental group post-intervention on hopelessness,
optimism, self-efficacy, self-esteem and resilience.
Transformation of hopelessness scores from pre-
intervention (M=10.82) to post-intervention (M=2.91)
was indicative of how AMBI has increased patients hope.
Similarly, changed scores of optimism pre-intervention
(M=4.04) to post-intervention (M=18.73) was also
indicative of the result of AMBI as a treatment was
effective enough for changing patients pessimism into
optimism. Significant t-values of self-efficacy (t=13.87)
and self-esteem (t=24.61) also indicated a similar effect
i.e. uplifting patients self-efficacy and self-esteem. Pre-
intervention scores (M=30.13) and post-intervention
score (M=90.21) of resilience also indicates that AMBI
not only improves hampered psychosocial factors of
patients with skin conditions but also helps in restoring
their fighting spirit (resilience).
Table 1: The M, SD and t-values of the experimental group
Variables Intervention M SD t-value p-value
Hopelessness
Pre 10.82 1.61
35.02
<0.001*
Post 2.91 0.9
Optimism
Pre 4.04 1.75
24.71
<0.001*
Post 18.73 2.32
Self-Efficacy
Pre 13.52 1.99
13.87
<0.001*
Post 29.95 5.21
Self-Esteem
Pre 14.43 5.21
24.61
<0.001*
Post 38.78 2.39
Resilience
Pre 30.13 2.68
21.63
<0.001*
Post 90.21 13.6
*sig. at 0.05 level
Table 2 shows that there was no significant difference
was found between pre-intervention and post-
intervention scores of waitlist group on hopelessness,
optimism, self-efficacy, self-esteem and resilience.
SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732
Akhouri et al., 2020
DOI: 10.21276/SSR-IIJLS.2020.6.5.2
Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2656
Table 2: The M, SD and t-values of waitlist group
Variables Intervention M SD t-value p-value
Hopelessness
Pre 10.86 1.32
2.66 0.01
Post 10.4 1.29
Optimism
Pre 4.04 2.05
0 1
Post 4.04 1.73
Self-Efficacy
Pre 13.36 2.15
0.43 0.66
Post 13.59 1.81
Self-Esteem
Pre 13.22 2.7
2.18 0.04
Post 12.09 1.63
Resilience
Pre 30.59 2.88
2.97 0.007
Post 29.95 2.68
*sig. at 0.05 level
Table 3 and Fig. 2 show a significant difference between
groups (Experimental and Waitlist) post-intervention.
Difference between experimental and waitlist group on
hopelessness was M=2.91 and M=10.4 respectively,
indicating that AMBI was effective enough to improve
patients hopelessness level and converting it into
hopefulness. A similar result was found on optimism
variable, i.e. M=18.73 (experimental) and M=4.04
(waitlist). Significant t-values of self-efficacy (14.43) and
self-esteem (26.43) variables of the experimental group
also indicate a similar result of the effectiveness of AMBI.
The difference in resilience of the experimental group
(M=90.21) and waitlist group (M=29.95) is also indicative
of the efficacy of AMBI. The overall improvement is
suggestive of how AMBI helps in the improvement of
various psychological factors affected by different skin
conditions when the comparison is made between
waitlist and experimental groups.
Table 3: Post-intervention difference between the experimental group and waitlist group on various psychosocial
domains
Variables Group M SD t-value p-value
Hopelessness
Experimental 2.91 0.9
35.01
<0.001*
Waitlist 10.4 1.29
Optimism
Experimental 18.73 2.32
24.43
<0.001*
Waitlist 4.04 1.73
Self-Efficacy
Experimental 29.95 5.21
14.43
<0.001*
Waitlist 13.59 1.81
Self-Esteem
Experimental 38.78 2.39
26.43
<0.001*
Waitlist 12.09 1.63
Resilience
Experimental 90.21 13.6
20.29
<0.001*
Waitlist 29.95 2.68
*sig. at 0.05 level
SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732
Akhouri et al., 2020
DOI: 10.21276/SSR-IIJLS.2020.6.5.2
Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2657
Fig. 2: The comparison and effect of acceptance and mindfulness-based intervention on experimental and waitlist
group
Table 4 and Fig. 3 shows the level of mindfulness has
increased for both the groups from pre-intervention to
post-intervention. Pre-intervention of AMBI, mindfulness
level of the experimental group was M=30.34 and
waitlist group was M=30.31. But after mindfulness
intervention (only to the experimental group), it was
found that for the experimental group it increased
(M=92.17) while for waitlist group mindfulness level
remain static (M=30.13). The statistical analysis indicates
mindfulness is an effective technique that improves
psychosocial factors associated with skin conditions as
well as increases the patient's mindfulness level.
Table 4: shows the level of mindfulness (mean values) of the experimental and waitlist group (pre and post-
intervention)
Intervention Experimental Group Waitlist Group t-value p-value
Pre-Intervention 30.34 30.31 0.38 0.7
Post-Intervention 92.17 30.13 20.27 <0.001*
*sig. at 0.05
Fig. 3: The level of mindfulness of experimental and waitlist group
DISCUSSION
Psychosocial factors significantly affect the skin of the
human being. Adolescents are more prone to skin
problems as there have been changes in their hormones
resulted in acne. High levels of psychological problems
were documented in studies.
Studies have indicated that 30-70% of people suffer from
skin conditions [2-4]
. Over the years, various researches
have been done to see the effect of mindfulness-based
interventions on physical conditions [20]
. P D’Alton et al.
[21]
have explored the association between the
mindfulness-based intervention and skin diseases and
SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732
Akhouri et al., 2020
DOI: 10.21276/SSR-IIJLS.2020.6.5.2
Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2658
has found significant improvement among the patients.
Our present study supported the previously done study.
In our study, it was seen that patients with different skin
disorders gradually showed improvement in all aspects
of psychological factors.
The present study assesses the level of hopelessness,
optimism, self-efficacy, self-esteem and resilience among
adolescents suffering from dermatological problems
(acne, eczema and psoriasis). Having skin problems
increase distress in adolescents. Our pre-intervention
assessment data indicates that before giving
intervention, psychosocial problems were high.
Fordham et al. [22]
found in their study that eight–week
mindfulness was an effective treatment for people with
psoriasis. The present study supports the previous study
and found acceptance and mindfulness therapy
significantly improve self-efficacy and self-esteem and
also improved quality of life. Our study further explores
the effect of acceptance and mindfulness-based
intervention (AMBI) on the level of mindfulness. After
every session mindfulness was assessed and found
gradually improvement (mindfulness) in experimental
group patients.
There’s a lack of studies that assess the level of
hopelessness, optimism, self-efficacy, self-esteem and
resilience among people suffering from skin conditions.
In the present study, it was found that the level of
hopelessness was more before the intervention but as
the AMBI took place their hopelessness changed into
hopefulness. Likewise, pessimism changed into optimism
when the intervention was given. Self-efficacy, self-
esteem and resilience have been reported to be restored
after the successful intervention, which was on the
lowest side [23,24]
. Various studies addressed that AMBI
provides relief from various psychological distresses. One
other study was done by Montgomery et al. [25]
it was
found that mindfulness helps reduce psychological
distress. This study was conducted on adult dermatology
patients. The present study shows significant
improvement in making patients self-efficient, increase
their self-esteem and improve mindfulness and quality of
life, help them maintain their mental hygiene with skin
conditions.
The result explains how mindfulness level increased as
the intervention took place, hence supporting previously
conducted study by where they conducted a meta-
analysis to prove how mindfulness-based therapies are
effective in the treatment of various conditions and
psychosocial factors associated with it [26]
.
CONCLUSIONS
Acceptance and mindfulness-based therapy is an
effective, non-pharmacological approach towards
treatment of psychosocial aspects related to skin
conditions in adolescents and this therapy has also been
very helpful in increasing the level of mindfulness in
them. The present therapy is proved itself that it
increased positive behaviours while feeling low due to
negative thoughts. This therapy is easy to understand,
can be regularly practised at home without the constant
guidance of the therapist and as the patient learns the
therapy during the session it can also help to reduce
future relapse. The present therapy is cost-effective and
the therapy itself has no side-effects.
In psycho-education, detail explanation was given that
this therapy is not only limited to negative psychosocial
aspects to skin diseases but would also prove to be
beneficial in future to all aspects related to mental
health.
CONTRIBUTION OF AUTHORS
Research concept- Dr. Deoshree Akhouri
Research design- Dr. Deoshree Akhouri
Supervision- Dr. Deoshree Akhouri
Materials- Dr. Mohammad Akram, Dr. Deoshree Akhouri
Data collection- Dr. Deoshree Akhouri, Maria Madiha
Data analysis and Interpretation- Dr. Deoshree Akhouri,
Maria Madiha, Dr. Mohammad Akram
Literature search- Dr. Deoshree Akhouri, Maria Madiha
Writing article- Dr. Deoshree Akhouri, Maria Madiha
Critical review- Dr. Mohammad Akram, Dr. Deoshree
Akhouri
Article editing- Dr. Deoshree Akhouri, Dr. Mohammad
Akram
Final approval- Dr. Deoshree Akhouri, Maria Madiha, Dr.
Mohammad Akram
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DOI: 10.21276/SSR-IIJLS.2020.6.5.2
Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2659
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  • 1. SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732 Akhouri et al., 2020 DOI: 10.21276/SSR-IIJLS.2020.6.5.2 Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2652 Impact of Acceptance and Mindfulness-Based Intervention as an Add-on Treatment for Skin Diseases-Acne, Eczema and Psoriasis Deoshree Akhouri1* , Maria Madiha2 , Mohammad Akram3 1 Sr. Assistant Professor, Department of Psychiatry, Jawaharlal Nehru Medical College & Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India 2 PhD Scholar, Department of Psychiatry, Jawaharlal Nehru Medical College & Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India 3 Associate Professor, Department of Radiotherapy, Jawaharlal Nehru Medical College & Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India *Address for Correspondence: Dr. Deoshree Akhouri, Sr. Assistant Professor, Department of Psychiatry, Jawaharlal Nehru Medical College & Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India E-mail: drdeoshreeakhouri@gmail.com Received: 15 Mar 2020/ Revised: 30 May 2020/ Accepted: 24 Aug 2020 ABSTRACT Background: According to the Global Burden of diseases, there are approximately 15 different types of skin diseases, such as acne, eczema, psoriasis, impetigo, abscess, etc. It was also noticed that acne, eczema and psoriasis are the topmost skin diseases prevalent worldwide. Although it is just the physical aspect mostly affected by skin conditions, the sufferer's psychological well- being is also affected. Various psychotherapies have been adopted to tackle the psychological aspects related to skin diseases. Acceptance and Mindfulness-Based interventions have proven to be effective for various conditions. The present study was planned to see the effect of Acceptance and Mindfulness on the treatment of psychological aspects related to the skin condition of adolescence. Methods: According to inclusion and exclusion criteria, 45 patients referred from Dermatology and Radiotherapy OPD was selected for psychosocial management. Different psychological tools were used for assessment purpose. Patients were divided into 2 groups: experimental and waitlist group. The experimental group was given therapy for 1 ½ month (6 sessions; weekly) and waitlist group was only on the prescribed medication by Dermatology OPD. Waitlist group was given therapy after the experimental group's therapy was terminated. Pre and post assessment was done to see the effect of acceptance and mindfulness intervention. Results: After 6 sessions of mindfulness, the experiment group improved significantly in all psychosocial dimensions in comparison to the waitlist group. The significant difference in the level of mindfulness was also found among both experimental and waitlist group. Conclusion: Acceptance and mindfulness-based therapy is an effective, non-pharmacological approach towards treatment of psychosocial aspects related to skin conditions. Key-words: Acne, Eczema, Acceptance and mindfulness, Adolescents, Skin condition INTRODUCTION According to the Global Burden of Diseases (GBD), there are approximately 15 different types of skin diseases, such as acne, eczema, psoriasis, impetigo, abscess, etc. How to cite this article Akhouri D, Madiha M, Akram M. Impact of Acceptance and Mindfulness-Based Intervention as an Add-on Treatment for Skin Diseases-Acne, Eczema and Psoriasis. SSR Inst. Int. J. Life Sci., 2020; 6(5): 2652-2659. Access this article online https://iijls.com/ It was also noticed that acne, eczema and psoriasis are the topmost skin diseases prevalent worldwide [1] . About 30-70% of individuals at present are suffering from skin diseases [2-4] . According to Frost and Sullivan's report of 2015, about 10-12% of the Indian population suffers from skin diseases like eczema and psoriasis, are majorly caused by pollution, global warming, ultraviolet rays, etc [5] . Although it is just the physical aspect mostly affected by skin conditions, the sufferer’s psychological well-being is also affected. Psychodermatology is an emerging discipline that addresses the importance of psychological Research Article
  • 2. SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732 Akhouri et al., 2020 DOI: 10.21276/SSR-IIJLS.2020.6.5.2 Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2653 intervention in the treatment of dermatological conditions. The non-pharmacological treatment along with medication has proven to be quite effective [6,7] . Various psychotherapies have been adopted to tackle the psychological aspects related to skin diseases. Skin diseases cause a great amount of stress, anxiety, depression, etc. reducing the quality of life [8] . Along with hormonal changes encountered during puberty, skin conditions are also a part of that phase. The reduced level of confidence, increased negative self-image, anxiety, etc. could hinder in their proper psychological well-being. To address the impact of skin diseases on an individual's psychology, Acceptance and Mindfulness- Based Interventions (AMBI) has been adopted. Various studies have been conducted on acceptance and mindfulness-based intervention, which was later termed as “third wave” or generation of cognitive behaviour therapy (CBT) [9-11] . Therefore, to overcome the challenges faced by adolescents, this study focuses its attention on the impact of acceptance and mindfulness- based intervention for the treatment of skin conditions of adolescents. MATERIALS AND METHODS Sample Collection- The study was undertaken from September 2018 to November 2018 in the Department of Psychiatry, Dermatology and Radiotherapy, Jawaharlal Nehru Medical College & Hospital, Aligarh Muslim University, Aligarh, UP, India. Referred patients diagnosed with acne, eczema and psoriasis were taken for the study. Total of 45 patients meeting the inclusion and exclusion criteria of the study were retained. Inclusion Criteria  Adolescents of 13-19 years of age  Both literate and illiterates were taken  Both genders were considered  Diagnosed skin disease-acne, eczema and psoriasis  Adolescents having reduced level of hopelessness, optimism, self-esteem, self-efficacy  Adolescents having a reduced level of mindfulness  Only the referred cases were taken  Guardians of adolescents, who gave written informed consent for the study Exclusion Criteria  Adolescents not falling under the age range  Adolescents having severe forms of psychiatric and medical conditions  Adolescents with high hopefulness, optimism, self- esteem, self-efficacy  Adolescents having an increased level of mindfulness  Those, who was not referred  Who, did not give written informed consent Tools used 1) Socio-Demographic and Clinical Data Sheet- Participant's details concerning their clinical and personal information was collected using semi- structured clinical and personal datasheet. 2) General Health Questionnaire-12- It was used to assess the general mental health of individuals [12] . 3) Beck Hopelessness Scale: It was developed by Aaron Beck and was a 20 items scale. Scores 0-3 was none or minimal hopelessness, 4-8 was Mild, 9-14 was Moderate and 15+ was severe [13] . 4) Life Orientation Test-Revised (LOT-R)- A 10-item measure of optimism versus pessimism. Of the 10 items, 3 items measure optimism, 3 items measure pessimism, and 4 items serve as fillers. Respondents rate each item on a 4-point scale: 0= strongly disagree, 1 = disagree, 2 = neutral, 3 = agree, and 4 = strongly agree. LOT-R is a revised version of the original LOT. The original LOT had 12 items: 4 worded positively, 4 worded negatively, and 4 fillers [14] . 5) General Self-Efficacy (GSE)- This scale was developed by Jerusalem and Schwarzer. He first developed originally the German version of this scale as 20-items and later he translated this scale into German to English and reduced 10-items. After a short period, Sud (2002) also translated this scale from English to Hindi version. Therefore, general self-efficacy scale (Hindi version) consists of 10-items rated on a four-point rating scale with the response categories i.e. (1) Not at all true, (2) Hardly true, (3) Moderately true, and (4) Exactly true. For scoring, all the ten items are added to yield the final composite score with a range from 10-40. The reliability coefficient of the scale was found to be ranging from 0.76 to 0.90 [15] . 6) Rosenberg Self-Esteem Scale- It was a 10-item scale that measures global self-worth by measuring both positive and negative feelings about the self. The scale is believed to be uni-dimensional.
  • 3. SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732 Akhouri et al., 2020 DOI: 10.21276/SSR-IIJLS.2020.6.5.2 Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2654 All items are answered using a 4-point Likert scale format ranging from strongly agree to strongly disagree [16] . 7) Adolescent Psychological Resilience Scale- This scale consists of 29 items, to be rated on 4 point rating. It assesses 6-factors, i.e. family support, confidant- friend support, school support, adjustment, sense of struggle and empathy [17] . 8) Five Facet Mindfulness Questionnaire (FFMQ)- It was a 15 items scale, with the 5-point rating. The higher the score, the higher is the mindfulness [18] . Procedure- Total of 45 patients suffering from acne, eczema and psoriasis were referred from Dermatology OPD for psychological management (therefore, no ethics committee was held for this specifically). Patients with severe eczema and psoriasis were also referred from the Department of the Radiotherapy after ruling out cancer. Since the participants were minors, their written informed consent was obtained from their parents or guardians. After obtaining permission, detailed assessment was done using above mentioned tools; they were also explained about the purpose of the study and the amount of time it will require, i.e. 6 weeks (weekly session). These 45 participants were then randomly divided into an experimental group and waitlist group. The experimental group consisted of 23 participants and waitlist group consisted of 22 participants. The experimental group was given acceptance and mindfulness-based intervention along with medication, whereas the waitlist group was the one who did not receive any kind of psychological intervention; they were only on medication prescribed by the Dermatology OPD. The waitlist group was informed that they will be given psychological intervention after 1½ months. The intervention was given in Psychological research lab of the psychiatry department, JNMC&H, AMU, up to 6 sessions for the next 11/2 months, asking them to visit weekly. For patients in the waitlist group, only pre and post- assessment were done for the next 11/2 months. They were given TAU. After completion of therapy, the above- mentioned scales were reassessed to see the effect of acceptance and mindfulness-based intervention (Experimental and Waitlist). The level of mindfulness was assessed immediately after every session (only the experimental group). Patients in the waitlist group were given psychological intervention after the termination of the experimental group’s therapy. Statistical Analysis- The statistical analysis was done using the Jeffreys's Amazing Statistics Program (JASP) [19] . Percentage (%) is used to see the proportionate part of the total sample (socio-demographic and clinical data). the t-test is used to compare between both the groups to see the effect of acceptance and mindfulness intervention on psychosocial factors after pre and post- intervention. Ethical approval details- The patients were referred from the Department of Dermatology and Radiotherapy for Psychosocial Management to Psychiatry OPD. The intervention was carried out in the Departmental of the research lab. RESULTS Fig. 1 shows the socio-demographic as well as clinical details of experimental and waitlist group. Most of the adolescents in both groups were females (Experimental= 69%; Waitlist= 72%), falling under the age range of 13- 17. Maximum adolescents were high-school students (Experimental= 56%; Waitlist= 54%). Maximum patients were from middle class (Experimental= 52%; Waitlist= 50%), residing in urban area (Experimental= 69%; Waitlist= 64%). Most of the patients were receiving treatment for the past for more than 6 months (Experimental= 56%; Waitlist= 54%).
  • 4. SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732 Akhouri et al., 2020 DOI: 10.21276/SSR-IIJLS.2020.6.5.2 Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2655 Fig. 1: shows socio-demographic and clinical details of all the participants Table 1 shows the difference between scores of experimental group post-intervention on hopelessness, optimism, self-efficacy, self-esteem and resilience. Transformation of hopelessness scores from pre- intervention (M=10.82) to post-intervention (M=2.91) was indicative of how AMBI has increased patients hope. Similarly, changed scores of optimism pre-intervention (M=4.04) to post-intervention (M=18.73) was also indicative of the result of AMBI as a treatment was effective enough for changing patients pessimism into optimism. Significant t-values of self-efficacy (t=13.87) and self-esteem (t=24.61) also indicated a similar effect i.e. uplifting patients self-efficacy and self-esteem. Pre- intervention scores (M=30.13) and post-intervention score (M=90.21) of resilience also indicates that AMBI not only improves hampered psychosocial factors of patients with skin conditions but also helps in restoring their fighting spirit (resilience). Table 1: The M, SD and t-values of the experimental group Variables Intervention M SD t-value p-value Hopelessness Pre 10.82 1.61 35.02 <0.001* Post 2.91 0.9 Optimism Pre 4.04 1.75 24.71 <0.001* Post 18.73 2.32 Self-Efficacy Pre 13.52 1.99 13.87 <0.001* Post 29.95 5.21 Self-Esteem Pre 14.43 5.21 24.61 <0.001* Post 38.78 2.39 Resilience Pre 30.13 2.68 21.63 <0.001* Post 90.21 13.6 *sig. at 0.05 level Table 2 shows that there was no significant difference was found between pre-intervention and post- intervention scores of waitlist group on hopelessness, optimism, self-efficacy, self-esteem and resilience.
  • 5. SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732 Akhouri et al., 2020 DOI: 10.21276/SSR-IIJLS.2020.6.5.2 Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2656 Table 2: The M, SD and t-values of waitlist group Variables Intervention M SD t-value p-value Hopelessness Pre 10.86 1.32 2.66 0.01 Post 10.4 1.29 Optimism Pre 4.04 2.05 0 1 Post 4.04 1.73 Self-Efficacy Pre 13.36 2.15 0.43 0.66 Post 13.59 1.81 Self-Esteem Pre 13.22 2.7 2.18 0.04 Post 12.09 1.63 Resilience Pre 30.59 2.88 2.97 0.007 Post 29.95 2.68 *sig. at 0.05 level Table 3 and Fig. 2 show a significant difference between groups (Experimental and Waitlist) post-intervention. Difference between experimental and waitlist group on hopelessness was M=2.91 and M=10.4 respectively, indicating that AMBI was effective enough to improve patients hopelessness level and converting it into hopefulness. A similar result was found on optimism variable, i.e. M=18.73 (experimental) and M=4.04 (waitlist). Significant t-values of self-efficacy (14.43) and self-esteem (26.43) variables of the experimental group also indicate a similar result of the effectiveness of AMBI. The difference in resilience of the experimental group (M=90.21) and waitlist group (M=29.95) is also indicative of the efficacy of AMBI. The overall improvement is suggestive of how AMBI helps in the improvement of various psychological factors affected by different skin conditions when the comparison is made between waitlist and experimental groups. Table 3: Post-intervention difference between the experimental group and waitlist group on various psychosocial domains Variables Group M SD t-value p-value Hopelessness Experimental 2.91 0.9 35.01 <0.001* Waitlist 10.4 1.29 Optimism Experimental 18.73 2.32 24.43 <0.001* Waitlist 4.04 1.73 Self-Efficacy Experimental 29.95 5.21 14.43 <0.001* Waitlist 13.59 1.81 Self-Esteem Experimental 38.78 2.39 26.43 <0.001* Waitlist 12.09 1.63 Resilience Experimental 90.21 13.6 20.29 <0.001* Waitlist 29.95 2.68 *sig. at 0.05 level
  • 6. SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732 Akhouri et al., 2020 DOI: 10.21276/SSR-IIJLS.2020.6.5.2 Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2657 Fig. 2: The comparison and effect of acceptance and mindfulness-based intervention on experimental and waitlist group Table 4 and Fig. 3 shows the level of mindfulness has increased for both the groups from pre-intervention to post-intervention. Pre-intervention of AMBI, mindfulness level of the experimental group was M=30.34 and waitlist group was M=30.31. But after mindfulness intervention (only to the experimental group), it was found that for the experimental group it increased (M=92.17) while for waitlist group mindfulness level remain static (M=30.13). The statistical analysis indicates mindfulness is an effective technique that improves psychosocial factors associated with skin conditions as well as increases the patient's mindfulness level. Table 4: shows the level of mindfulness (mean values) of the experimental and waitlist group (pre and post- intervention) Intervention Experimental Group Waitlist Group t-value p-value Pre-Intervention 30.34 30.31 0.38 0.7 Post-Intervention 92.17 30.13 20.27 <0.001* *sig. at 0.05 Fig. 3: The level of mindfulness of experimental and waitlist group DISCUSSION Psychosocial factors significantly affect the skin of the human being. Adolescents are more prone to skin problems as there have been changes in their hormones resulted in acne. High levels of psychological problems were documented in studies. Studies have indicated that 30-70% of people suffer from skin conditions [2-4] . Over the years, various researches have been done to see the effect of mindfulness-based interventions on physical conditions [20] . P D’Alton et al. [21] have explored the association between the mindfulness-based intervention and skin diseases and
  • 7. SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732 Akhouri et al., 2020 DOI: 10.21276/SSR-IIJLS.2020.6.5.2 Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2658 has found significant improvement among the patients. Our present study supported the previously done study. In our study, it was seen that patients with different skin disorders gradually showed improvement in all aspects of psychological factors. The present study assesses the level of hopelessness, optimism, self-efficacy, self-esteem and resilience among adolescents suffering from dermatological problems (acne, eczema and psoriasis). Having skin problems increase distress in adolescents. Our pre-intervention assessment data indicates that before giving intervention, psychosocial problems were high. Fordham et al. [22] found in their study that eight–week mindfulness was an effective treatment for people with psoriasis. The present study supports the previous study and found acceptance and mindfulness therapy significantly improve self-efficacy and self-esteem and also improved quality of life. Our study further explores the effect of acceptance and mindfulness-based intervention (AMBI) on the level of mindfulness. After every session mindfulness was assessed and found gradually improvement (mindfulness) in experimental group patients. There’s a lack of studies that assess the level of hopelessness, optimism, self-efficacy, self-esteem and resilience among people suffering from skin conditions. In the present study, it was found that the level of hopelessness was more before the intervention but as the AMBI took place their hopelessness changed into hopefulness. Likewise, pessimism changed into optimism when the intervention was given. Self-efficacy, self- esteem and resilience have been reported to be restored after the successful intervention, which was on the lowest side [23,24] . Various studies addressed that AMBI provides relief from various psychological distresses. One other study was done by Montgomery et al. [25] it was found that mindfulness helps reduce psychological distress. This study was conducted on adult dermatology patients. The present study shows significant improvement in making patients self-efficient, increase their self-esteem and improve mindfulness and quality of life, help them maintain their mental hygiene with skin conditions. The result explains how mindfulness level increased as the intervention took place, hence supporting previously conducted study by where they conducted a meta- analysis to prove how mindfulness-based therapies are effective in the treatment of various conditions and psychosocial factors associated with it [26] . CONCLUSIONS Acceptance and mindfulness-based therapy is an effective, non-pharmacological approach towards treatment of psychosocial aspects related to skin conditions in adolescents and this therapy has also been very helpful in increasing the level of mindfulness in them. The present therapy is proved itself that it increased positive behaviours while feeling low due to negative thoughts. This therapy is easy to understand, can be regularly practised at home without the constant guidance of the therapist and as the patient learns the therapy during the session it can also help to reduce future relapse. The present therapy is cost-effective and the therapy itself has no side-effects. In psycho-education, detail explanation was given that this therapy is not only limited to negative psychosocial aspects to skin diseases but would also prove to be beneficial in future to all aspects related to mental health. CONTRIBUTION OF AUTHORS Research concept- Dr. Deoshree Akhouri Research design- Dr. Deoshree Akhouri Supervision- Dr. Deoshree Akhouri Materials- Dr. Mohammad Akram, Dr. Deoshree Akhouri Data collection- Dr. Deoshree Akhouri, Maria Madiha Data analysis and Interpretation- Dr. Deoshree Akhouri, Maria Madiha, Dr. Mohammad Akram Literature search- Dr. Deoshree Akhouri, Maria Madiha Writing article- Dr. Deoshree Akhouri, Maria Madiha Critical review- Dr. Mohammad Akram, Dr. Deoshree Akhouri Article editing- Dr. Deoshree Akhouri, Dr. Mohammad Akram Final approval- Dr. Deoshree Akhouri, Maria Madiha, Dr. Mohammad Akram REFERENCES [1] Hay RJ, Johns NE, Williams HC, Bolliger IW, Dellavalle RP, et al. The global burden of skin disease in 2010: An analysis of the prevalence and impact of skin conditions. J Investig Dermatol., 2014; 134(6): 1527- 34. [2] Hay RJ, Fuller LC. The assessment of dermatological needs in resource-poor regions. International journal of dermatology. 2011; 50(5): 552-57.
  • 8. SSR Inst. Int. J. Life Sci. ISSN (O): 2581-8740 | ISSN (P): 2581-8732 Akhouri et al., 2020 DOI: 10.21276/SSR-IIJLS.2020.6.5.2 Copyright © 2015–2020| SSR-IIJLS by Society for Scientific Research under a CC BY-NC 4.0 International License Volume 06 | Issue 05 | Page 2659 [3] Bickers DR, Lim HW, Margolis D, Weinstock MA, Goodman C, et al. The burden of skin diseases: 2004: A joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. J Am Academy Dermatol., 2006; 55(3): 490-500. [4] Schofield JGD, Douglas G, Hywel W. Skin conditions in the UK: health care needs assessment, 2009. [5] Frost S. BioSpectrum Bureau [Internet] Skin diseases to grow in India by 2015: Report, 2014. https://www.biospectrumindia.com/news/73/8437/ skin-diseases-to-grow-in-india-by-2015-report.html. [6] Shenefelt PD. Psychological interventions in the management of common skin conditions. Psychol Res Behav Manag., 2010; 3: 51. [7] Lavda AC, Webb TL, Thompson AR. A meta‐analysis of the effectiveness of psychological interventions for adults with skin conditions. Br J Dermatol., 2012; 167(5): 970-79. [8] Basavaraj KH, Navya MA, Rashmi R. Relevance of psychiatry in dermatology: Present concepts. Indian J psychiatr., 2010; 52 (3): 270. [9] McKellar JD, Clark ME, Shriner J. The cognitive specificity of associative responses in patients with chronic pain. Br J Clin Psychol., 2003; 42(1): 27-39. [10]Schut C, Mollanazar NK, Kupfer J, Gieler U, Yosipovitch G. Psychological interventions in the treatment of chronic itch. Acta dermato- venereologica, 2016; 96(2): 157-63. [11]Hayes SC. Acceptance and commitment therapy, relational frame theory, and the third wave of behavioral and cognitive therapies–republished article. Behav Ther., 2016; 47(6): 869-85. [12]Goldberg D. General health questionnaire (GHQ-12) edn. NFER-Nelson: Windsor, UK, 1992. [13]Beck AT, Steer RA. Beck Hopelessness Scale manual. The Psychological Corporation. (LAST UPDATE), 2020. [14]Scheier MF, Carver CS, Bridges MW. Distinguishing optimism from neuroticism (and trait anxiety, self- mastery, and self-esteem): a reevaluation of the Life Orientation Test. J Personality Social Psychol., 1994; 67(6): 1063. [15]Zhang JX, Schwarzer R. Measuring optimistic self- beliefs: A Chinese adaptation of the General Self- Efficacy Scale. Psychologia: Int J Psychol Orient, 1995. [16]Rosenberg M. Society and the adolescent self-image. Princeton university press, 2015. [17]Bulut S, Doğan U, Altundağ Y. Adolescent psychological resilience scale: validity and reliability study. Contemp Psychol Suvremena Psihologija, 2013; 16(1): 21-32. [18]Baer RA, Smith GT, Hopkins J, Krietemeyer J, Toney L. Using self-report assessment methods to explore facets of mindfulness. Assess., 2006, 13(1): 27-45. [19]JASP. A fresh way to do Statistics. https://jasp- stats.org/. [20]Carlson L. Review Article: Mindfulness-Based Interventions for Physical Conditions: A Narrative Review Evaluating Levels of Evidence. Int Scholarly Res Notices, 2012. [21]D’Alton P, Kinsella L, Walsh O, Sweeney C, Timoney I, et al. Mindfulness-based interventions for psoriasis: A randomized controlled trial. Mindfulness, 2019; 10(2): 288-300. [22]Fordham B, Griffiths CEM, Bundy C. A pilot study examining mindfulness-based cognitive therapy in psoriasis. Psychol Health Med., 2015; 20(1): 121-27. [23]Sanaei H, Hossini SA, Jamshidifar Z. Effectiveness of mindfulness training on self-efficacy of patients infected by breast cancer. Procedia-Social Behav Sci., 2014; 159(23): 426-29. [24]Shojaeyan M, Abolmaali K. Effectiveness of cognitive therapy-based mindfulness on increasing the psychological capital of veterans. Fall., 2016; 8(4): 195-201. [25]Montgomery K, Norman P, Messenger AG, Thompson AR. The importance of mindfulness in psychosocial distress and quality of life in dermatology patients. Br J Dermatol., 2016; 175(5): 930-36. [26]Li G, Yuan H, Zhang W. The effects of mindfulness- based stress reduction for family caregivers: systematic review. Arch Psychiatr Nursing, 2016; 30(2): 292-99. Open Access Policy: Authors/Contributors are responsible for originality, contents, correct references, and ethical issues. SSR-IIJLS publishes all articles under Creative Commons Attribution- Non-Commercial 4.0 International License (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/legalcode