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A Study of the Shingles Vaccine 
By Linda Langevoort 
PHE3025 – Research Methods in Public Health 
South University Online 
November 18, 2014
Table of Contents 
1. Introduction 
2. Synopsis 
3. Symptoms of Shingles 
4. History 
5. Antecedents to Shingles 
6. Epidemiology of Shingles 
7. Qualitative Research Design 
8. Sampling Plan 
9. The Interview 
10. Research strengths 
11. Research weaknesses
Introduction 
Shingles (or herpes-zoster),comes from the varicella-zoster 
virus, (the same virus as chicken pox). People 
primarily susceptible to the virus are mature adults of 
the age 60 and over, or persons with weakened immune 
systems, or pregnant women and newborns. The virus 
lies dormant in the body and can be triggered at any 
time to emerge. The reason for this emergence is not 
completely understood, but a vaccine called the 
varicella-zoster vaccine or Zostavax, is available for 
those who do not have a present case of the Shingles.
Synopsis 
Healthcare personnel are recommended to have certain 
vaccinations (if not already immunized) to protect from 
certain diseases due to risk of workplace exposures that 
could be present. (Immunization Action Coalition, 2014) 
Those diseases are Hepatitis B, Influenza, 
Measles/Mumps/Rubella(MMR),varicella (chickenpox), 
Tetanus/Diptheria/Pertussis, and meningococcal. 
(Immunization Action Coalition, 2014) 
In this study I would like to research why so few 
healthcare personnel receive the Shingles vaccine and 
the reasons behind it.
Symptoms 
The Shingles presents as a stripe of blisters. Most 
commonly it is found on the torso and wraps around. 
Some cases have been reported in one eye or the side of 
the neck or face. The small lesions are itchy and painful. 
They progress to be blisters filled with fluid. The blisters 
break open and then scab over in 4-5 weeks. The scab 
falls off and pain and itching subside. Sometimes after 
symptoms subside, some pain may persist at the site 
after the blisters heal. Other symptoms common are 
fever, chills, achiness, fatigue or headache. (The Mayo Clinic, 2011)
History of Shingles 
“Clinical observations of the relationship between 
varicella and herpes zoster were made in 1888 by von 
Bokay, when children without evidence of varicella 
immunity acquired varicella after contact with herpes 
zoster. VZV was isolated from vesicular fluid of both 
chickenpox and zoster lesions in cell culture by Thomas 
Weller in 1954. Subsequent laboratory studies of the 
virus led to the development of a live attenuated 
varicella vaccine in Japan in the 1970s. The vaccine was 
licensed for use in the United States in March 1995.” 
(The Centers for Disease Control and Prevention, 2012)
Antecedents to Shingles Triggers can be: 
-Stress 
-Stressful life events 
-Depression 
-Age 
-Nutritional Status 
-Presence of other disorders 
-Having a compromised 
immune system. 
-Personality 
psychopathology 
(Huff Post Science, Depression) (Innovations in Clinical Neuroscience, 2014)
Varicella Epidemiology 
Reservoir: The human body 
Transmission: Direct contact or air 
droplet. 
Communicability: One - two days 
before. 
Four-five days after onset of rash. 
Can be longer in those 
immunocompromised. 
Epidemiology 
(Epidemiologist: Jobs, Careers & Salary Outlook) (The Center for Disease Control and Prevention, 2012)
ResearchDesign Technique 
The research design used in this study is qualitative and 
the process is by interviewing. The study hopefully will 
uncover why healthcare personnel do not want the 
Shingles vaccine and why.
Population: 
Healthcare personnel 
(doctors, nurses, aids, lab 
workers, etc.) 
Selection: 
Random 
Gender: 
Males and females 
Variables of the study: 
Interview questions 
(Creswell, J., pp. 158-161, 2014) 
Sampling Plan
The Interview 
Have you ever had 
the Shingles or the 
Shingles vaccine? 
Interview 
Questions 
Why did you/ did 
you not have the 
Shingles vaccine? 
What are your 
primary job duties? 
What is your age? 
Does the 
healthcare agency 
you are employed 
at pay for the 
vaccine for 
workers? 
Did you have the 
chicken pox at any 
time in your life?
Strengths of the Design 
It is unbiased. 
No inferences are made 
in the questioning. 
No hypotheses were 
drawn while conducting 
the interviews. 
Analysis was simple and 
straightforward. 
Answers can be used to 
better understand the 
healthcare professionals’ 
opinion.
Weakness of the Design 
There is no statistical 
significance. 
Reliability of the 
answers. 
Small sample group. 
Based on inquiry 
alone.
References 
Creswell, J., 2014. Research design: qualitative, quantitative and mixed methods approaches, 4th Edition, Sage Publications, Inc. 
Huff Post Science. (Producer). (2014, April 23). Depression [Web Photo]. Retrieved from 
http://www.huffingtonpost.com/jonathan-rottenberg/why-there-will-be-no-cure-for-depression_b_4824289.html 
Immunization Action Coalition. (2014, March).Healthcare personnel vaccination recommendations. Retrieved from 
http://www.immunize.org/catg.d/p2017.pdf 
Innovations in Clinical Neuroscience. (2014, May).Herpes zoster and postherpetic neuralgia: An examination of psychological 
antecedents. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140624/ 
The Center for Disease Control and Prevention. (2012, May). Varicella epidemiology and prevention of vaccine-preventable diseases. 
Retrieved from http://www.cdc.gov/vaccines/pubs/pinkbook/varicella.html 
The Mayo Clinic. (2011, September 1). Shingles. Retrieved from http://www.mayoclinic.org/diseases-conditions/ 
shingles/basics/definition/con-20019574

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Su phe3025 w3_a2_langevoort_l

  • 1. A Study of the Shingles Vaccine By Linda Langevoort PHE3025 – Research Methods in Public Health South University Online November 18, 2014
  • 2. Table of Contents 1. Introduction 2. Synopsis 3. Symptoms of Shingles 4. History 5. Antecedents to Shingles 6. Epidemiology of Shingles 7. Qualitative Research Design 8. Sampling Plan 9. The Interview 10. Research strengths 11. Research weaknesses
  • 3. Introduction Shingles (or herpes-zoster),comes from the varicella-zoster virus, (the same virus as chicken pox). People primarily susceptible to the virus are mature adults of the age 60 and over, or persons with weakened immune systems, or pregnant women and newborns. The virus lies dormant in the body and can be triggered at any time to emerge. The reason for this emergence is not completely understood, but a vaccine called the varicella-zoster vaccine or Zostavax, is available for those who do not have a present case of the Shingles.
  • 4. Synopsis Healthcare personnel are recommended to have certain vaccinations (if not already immunized) to protect from certain diseases due to risk of workplace exposures that could be present. (Immunization Action Coalition, 2014) Those diseases are Hepatitis B, Influenza, Measles/Mumps/Rubella(MMR),varicella (chickenpox), Tetanus/Diptheria/Pertussis, and meningococcal. (Immunization Action Coalition, 2014) In this study I would like to research why so few healthcare personnel receive the Shingles vaccine and the reasons behind it.
  • 5. Symptoms The Shingles presents as a stripe of blisters. Most commonly it is found on the torso and wraps around. Some cases have been reported in one eye or the side of the neck or face. The small lesions are itchy and painful. They progress to be blisters filled with fluid. The blisters break open and then scab over in 4-5 weeks. The scab falls off and pain and itching subside. Sometimes after symptoms subside, some pain may persist at the site after the blisters heal. Other symptoms common are fever, chills, achiness, fatigue or headache. (The Mayo Clinic, 2011)
  • 6. History of Shingles “Clinical observations of the relationship between varicella and herpes zoster were made in 1888 by von Bokay, when children without evidence of varicella immunity acquired varicella after contact with herpes zoster. VZV was isolated from vesicular fluid of both chickenpox and zoster lesions in cell culture by Thomas Weller in 1954. Subsequent laboratory studies of the virus led to the development of a live attenuated varicella vaccine in Japan in the 1970s. The vaccine was licensed for use in the United States in March 1995.” (The Centers for Disease Control and Prevention, 2012)
  • 7. Antecedents to Shingles Triggers can be: -Stress -Stressful life events -Depression -Age -Nutritional Status -Presence of other disorders -Having a compromised immune system. -Personality psychopathology (Huff Post Science, Depression) (Innovations in Clinical Neuroscience, 2014)
  • 8. Varicella Epidemiology Reservoir: The human body Transmission: Direct contact or air droplet. Communicability: One - two days before. Four-five days after onset of rash. Can be longer in those immunocompromised. Epidemiology (Epidemiologist: Jobs, Careers & Salary Outlook) (The Center for Disease Control and Prevention, 2012)
  • 9. ResearchDesign Technique The research design used in this study is qualitative and the process is by interviewing. The study hopefully will uncover why healthcare personnel do not want the Shingles vaccine and why.
  • 10. Population: Healthcare personnel (doctors, nurses, aids, lab workers, etc.) Selection: Random Gender: Males and females Variables of the study: Interview questions (Creswell, J., pp. 158-161, 2014) Sampling Plan
  • 11. The Interview Have you ever had the Shingles or the Shingles vaccine? Interview Questions Why did you/ did you not have the Shingles vaccine? What are your primary job duties? What is your age? Does the healthcare agency you are employed at pay for the vaccine for workers? Did you have the chicken pox at any time in your life?
  • 12. Strengths of the Design It is unbiased. No inferences are made in the questioning. No hypotheses were drawn while conducting the interviews. Analysis was simple and straightforward. Answers can be used to better understand the healthcare professionals’ opinion.
  • 13. Weakness of the Design There is no statistical significance. Reliability of the answers. Small sample group. Based on inquiry alone.
  • 14. References Creswell, J., 2014. Research design: qualitative, quantitative and mixed methods approaches, 4th Edition, Sage Publications, Inc. Huff Post Science. (Producer). (2014, April 23). Depression [Web Photo]. Retrieved from http://www.huffingtonpost.com/jonathan-rottenberg/why-there-will-be-no-cure-for-depression_b_4824289.html Immunization Action Coalition. (2014, March).Healthcare personnel vaccination recommendations. Retrieved from http://www.immunize.org/catg.d/p2017.pdf Innovations in Clinical Neuroscience. (2014, May).Herpes zoster and postherpetic neuralgia: An examination of psychological antecedents. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140624/ The Center for Disease Control and Prevention. (2012, May). Varicella epidemiology and prevention of vaccine-preventable diseases. Retrieved from http://www.cdc.gov/vaccines/pubs/pinkbook/varicella.html The Mayo Clinic. (2011, September 1). Shingles. Retrieved from http://www.mayoclinic.org/diseases-conditions/ shingles/basics/definition/con-20019574