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Presentation at the University of Cape Town, Aug. 5, 2011. This talk was part of the OpenUCT initiative and the Scholarly Communication in Africa Programme. It provides an overview of the changing research landscape and the particular importance of open access and other forms of open collaboration for solving some of the pressing problems of development research. The presentation argues for the importance of policy development in support of research collaboration and the development of enriched metrics for evaluating the development impact of research.