A REVIEW IN MARINE PHARMACEUTICALS PRESENTED BY GRACY RACHEL ,CHILKUR BALAJI COLLEGE OF PHARMACY, HYDERABAD ,TELANGANA

1. A REVIEW ON MARINE PHARMACEUTICALS
MINI PROJECT/SEMINAR
BY
GRACY RACHEL-(13GD1R0030)
UNDER THE GUIDANCE OF
Mr. K. ASHOK BABU M. Pharm
Assistant professor
Department of Pharmacy
CHILKUR BALAJI COLLEGE OF PHARMACY
(APPROVED BY AICTE, NEW DELHI)
(Affiliated to Jawaharlal Nehru Technological University, Hyderabad,Telangana)

2. CONTENTS
1.INTRODUCTION
2.MARINE NATURAL PRODUCTS
3.DISCOVERY
4.DIVING INTO MARINE DRUG DEVELOPMENT
5.POLLUTION
6.MARINE BIODIVERSITY, ANTI-CANCER DRUG
DEVELOPMENT
7.MARINE PHARMACOGNOSY
8.MARINE PHARMACOLOGY
9.DRUGS OF MARINE ORIGIN
10.DRUGS AND THEIR SOURCES
11.CONCLUSION
12.REFERENCES

6. DISCOVERY

7. DIVING INTO MARINE DRUG DEVELOPMENT
• PROPERTIES DISCOVERED:
• Anti-bacterial
• Anti-coagulant
• Anti-fungal
• Anti- protozoal
• Anti-tuberculosis
• Anti-viral

8. POLLUTION

9. MARINE BIODIVERSITY – ANTICANCER
DRUG DEVELOPMENT
• Various active anticancer agents are derived from
plants and terrestrial microbes.
• The oceans cover about 70% of the earth’s surface,
and the marine environment includes tremendous
biodiversity.
• The isolation of C-nucleosides from the Caribbean
sponge, cryptotheca crypta, four decades ago,
provided the basis for the synthesis of cytarabine, the
first marine derived anticancer agent to be developed
for clinical use.

10. MARINE PHARMACOGNOSY

11. MARINE PHARMACOLOGY

13. DRUGS AND THEIR SOURCES

14. CONCLUSION
• In short the marine world evidently enjoys status of holding an enormous
and tremendous potent making discovering of a plethora of al together
newer lead molecules in the development of medicinally potent therapeutic
agents that are active against a variety if parasites and infectious
alignment.
• With the advent of recent development and use of technologically advanced
computer aided sophisticated analytical instruments have turned this novel
dream like fictionsinto reality

15. REFERENCES
• 1. http://www.alexisduclos.com/PDF/Promise_of_the_se a.pdf
• 2. Blunden G Biologically Active Compounds from Marine Organisms. Phytother Res 2001;
15: 89-94.
• 3. Colwell, Rita Biotechnology in the Marine Sciences in Colwell, Sins key, and Pursier.
Biotechnology in the Marine Sciences, New York: John Wiley; 1984.
• 4. http://www.berr.gov.uk/files/file10469.pdf
• 5. Okami Y, Motta K, Yoshida M, Ikeda D, Kondo S, Umeezawa H New Aminoglycoside
Antibiotics, Istamycins A and B. J Antiriot 1979; 32: 964-966
• . 6. Stud M, Mugishima T, Komatsu K, Some T, Tanaka M, Mikami Y, et al. Modiolides A and
B, Two New 10-Membered Macrolides form a Marine-Derived Fungus. J Nat Prod 2003; 66:
1395-1399.
• 7. Shigemori H, Komatsu K, Mikami Y, Seragakinone A, Kobayashi J A New Pentacyclic
Metabolite from a Marine-Derived Fungus. Tetrahedron 1999; 55: 14925-14930.
• 8. Komatsu K, Shigemori H, Shire M, Kobayashi J Revised Stereochemistry and Biosynthesis
of Seragakinone A. Tetrahedron 2000; 56: 8841-8844.
• 9. Hooper GJ, Davies-Coleman MT, Coetzee PS New Antimicrobial C14 and C13 Amines
from a South African Marine Ascidians. Nat Prod Let 1995; 6: 31- 35.
• 10. Rinehart KL, Shield LS, Cohen-Parsons M. Pharmaceutical and Bioactive Natural
Products. 2nd ed. New York: Plenum Press 1995.
• 11. Zabriskie TM, Mayne CL, Ireland CM Patellazole C: A Novel Cytotoxic Macrolide from
Lissoclinum patella. Jam Chem. Soc 1988; 110: 7919-7920. Yogesh Marti et al /Int.J.
ChemTech Res.2010,2(4) 2216
• 12. Komatsu K, Shigemori H, Mikami Y, Kobayashi J Seulezonones A and B, Two
Metabolites Possessing a Phenalenone-Dione Skeleton from a Marine-Derived Fungus
Penicillium sp. J Nat Prod; 63: 408-409. 1

16. THANK YOU