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1 Give three (3) properties of viruses. [3] 2 With the aid of an appropriately labelled graph,
explain what generally happens during the infection process of a typical eukaryotic virus. [5] 3
Name and discuss the mechanism that Adenovirus C uses to generate multiple RNA transcripts
of differing lengths from the single major large promoter. [5] 4 How do the two influenza virus
receptors co-operate with each other during viral attachment? [2] 5 Outline some of the
mechanisms/methods that HIV utilizes to enter susceptible T4 cells. [5] 6 In phage MS2 the
replicase gene is inaccessible to ribosomes due to high intramolecular H-bonding of the RNA
genome. How and when then, is the replicase gene translated? [5] 7 How is oncogenesis
stimulated during SV40 infection? [3] 8 What mechanism does SV40 use to ensure that the host
DNA polymerase preferentially replicates viral DNA? [2] 9 The Adeno Associated Virus (AAV)
lacks a DNA or RNA primer yet the genome is still replicated. How is this achieved? 10 Discuss
transcription as it occurs in the Togaviridae. [6] 11 Explain how full systemic infection is
achieved by viruses in the Geminiviridae group. 12 What is the role of the VP4 capsid protein
present in Poliovirs C ? [5]

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