Tissue transplant rejection is primarily atype I reaction.type I.pdf

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Tissue transplant rejection occurs when the host immune system reacts to antigens in the transplanted organ from a foreign organism. This is a type IV hypersensitivity reaction where T-cells mediate an immune response against the major histocompatibility complex proteins on the surface of donated tissue that help the immune system identify foreign substances. Tissue transplant rejection can take weeks to months to occur as an immune response against the transplanted organ.

Education

Tissue transplant rejection is primarily a
type I reaction.
type II reaction.
type III reaction.
type IV reaction.
type V reaction.
Solution
Organ transplantation is the replacement of a host's dysfunctional tissue with a healthy tissue
from another organism (host). Since the transplanted organ is from another (foreign) organism,
the host's immune system reacts to the foreign antigens. This immunological response is a
hypersensitivity response called Transplant Rejection.
During a Tissue Transplant, the transplant rejection is a T-Cell mediated response against foreign
Major Histocompatibility Complex in the donated organ. The Major Histocompatibility Complex
are a group of genes that code for proteins found on the surfaces of the donated tissue that helps
the immune system to recognize the foreign substances. It usualy takes around weeks to months.
Therefore, a tissue transplant rejection is a Type IV hypersensitivity reaction.

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