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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 05 | May 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 2011
AUTOMATIC COVID DETECTION USING COUGH SIGNAL ANALYSIS
P. SELVAVENI1, G. RENISHA2
1Student, Dept of ECE, GCE-Tirunelveli, Tamil Nadu, India
2Assistant Professor, Dept of ECE, GCE-Tirunelveli, Tamil Nadu, India
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - Remote observation and measurements are
valuable tools for medical applications and they are notably
necessary inside the context of pandemic outbreaks similarto
this COVID-19. COVID-19 subjects particularly together with
symptomless, can be accurately discriminated from forced
cough mobile transportable recordings. The information
consists of a set of audiosamplescollected fromVirufy/clinical
data. Cough recordings are remodeled with Modified Mel
frequency cepstral coefficient (MFCC) and inputted into a k-
Nearest neighbor (k-NN) classifier during this technique was
used to obtain models identifying cough with high
performance classifiers were obtained for many of them,
including COVD-19. These results are preliminary and there’s
potential to enhance, as there have been obtained from
dataset. In this technique free, invisible, anytime, accessibleby
anyone, no laboratory testing is needed, no cost, instantly
distributable, large scale COVID-19 symptomless screening
tool to reinforce practical use cases can be daily screening of
students, workers, and public as schools, jobs, and transport
reopen, or pool testing to quickly alert of outbreaks in teams.
COVID-19 positive samples in our dataset are haphazardly
choose the quality of COVID 19 negative subjects for a
balanced distribution. The topic forced- cough audios and
diagnostic results were used to train and validate the COVID-
19 discriminator.
Key Words: Covid-19,MFCC,DFT,k-NN,MODIFIEDMFCC,
DWT, speech recognition,
1. INTRODUCTION
Coronavirus disease 2019 (COVID-19) is a highlycontagious
viral illness caused by severe acute respiratory syndrome
SARAS-CoV-2. A Worldwide coordinated effortis requiredto
prevent the further spread of the virus. A deadly disease
defined as “occurring as over wide geographical region and
affecting an exceptionally high proportion of thepopulation.
The virus has inflicted billion of lives across the world in
some ways e.g.: physically, psychologically, socially.
Compared to other diseases COVID-19 has had: significantly
higher transmissibility; worst post recovery; frequent
mutation; resulting in higher mortalities and uncontrolled
virulence. The clinical manifestations of this particularvirus
have exhibited deleterious impacts on systems apart from
the respiratory systems. In fact, across the world, outbreaks
are threatening a second wave, which within the Spanish flu
was far more dangerous than the primary one. These
outbreaks are very hard to contain with current testing
approaches are unless region wide confinement measures
were sustained. This partly because limitations of current
viral and serology tests and also the lack of complementary
pre-screening methods to efficiently select who should be
tested. They are expensive to creating thepriceoftestingthe
entire country day by day impossible. COVID-19 symptoms
may range from none to deadly. Severe illness is more likely
in elderly patients andthose withcertainunderlyingmedical
conditions. COVID-19 is airborne,spreadvia aircontainment
by microscope virions. Then risk of infection is highest
among people in close proximity, but can occur over long
distances, particularly indoors in poorly ventilated areas.
transmission rarely occurs via containmentsurfaceorfluids.
Infected peoples are typically contagious for 10 days, often
beginning before or without symptoms.
1.1 Coronavirus
Coronavirus is a large family of viruses that causeillness like
respiratorydiseasesorgastrointestinal diseases.Respiratory
diseases can range from the respiratory disease to more
severe diseases e.g.
 Middle East Respiratory Syndrome (MERS-CoV)
 Severe Acute Respiratory Syndrome (SARS-CoV)
A completely unique corona virus may be a new strain that
has not been identifiedinhumanspreviously.Oncescientists
determine exactly what coronavirus it is, the furnish it name
as a within the case of COVID-19, the viruscausingitisSARS-
CoV-2).
Fig -1: Microscopic picture of coronavirus
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 05 | May 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 2012
Coronaviruses got their name from the way thatthey appear
under a microscope. The virus consists of surrounded by an
envelope with protein spikes. The gives it the look of a
crown. The word corona means “crown’” in Latin.
Coronavirus are transmitted between animals and humans.
It's been determined that MERS-COV was transmitted from
dromedary camels to humans and SARS from civet cat to
humans. The source of SARS-COV2 is yet to be determined,
but investigations are ongoing to spot the zoonotic source to
the outbreak.
2. DATABASE USED
Recording was available in various browser and devices
(virufy/clinical data). data was anonymized before being
collected on our secure samples were saved without
compression in WAV format. Samples that had no audio
content were removed. Segmentation was performedonthe
cough recordings used to train and test. COVID- 19 positive
samples in our dataset are randomly selected the identical
range of COVID 19 negative subjects for a balanced
distribution. The topic forced- cough audios and diagnostic
results were used to train and validate the COVID-19
discriminator.
3.FEATURE EXTRACTION
Feature extraction is an important and basic step of speech
recognition. It is associate in nursing exceptional kind of
property decreases technique that is used to reducethedata
which is intensive to be ready by calculation. In speech
recognition, Feature extraction is that the way towards
holding valuable data of the signal whereas eliminating of
repetitive and undesirable data. It’s the parameterization of
the speech signal. It is the procedure of fixing the signal to
digital type, measuring some imperative character of the
signal, for example, energyandfrequencyresponses. Speech
recognition could be a supervised learning task. In speech
recognition problem input will be the audio signal and we
got to predict the text from the audio signals. take the
raw audio signal as input to our model be as a result of
there will be a lot of noise within the audio signal. It is
determined that extracting options from the audio signal
and using it as input to the bottom model can
manufacture much better performance than directly
considering raw audio signal as input
MFCC is that the wide used technique for extracting the
options from the audio signal. Instead of Mel frequency
cepstral coefficient using (MFCC) using Discrete Fourier
Transform (DFT) here modified MFCC withDiscrete wavelet
transform (DWT) is used to get better accuracy then MFCC
using DFT.
Fig -2: Block diagram of modified MFCC
4.RESULTS
Recording was out there in numerous browser and devices
(virufy/clinical data). data was anonymized before being
collected on our secure samples were saved without
compression in WAV format. Samples that had no audio
content were removed. Segmentation was performedonthe
cough recordings used to train and check.
COVID-19 positive samples in our dataset are randomly
selected the same number of COVID 19 negative subjects for
a balanced distribution. The topic forced- cough audios and
diagnostic results were used totrainandvalidatethe COVID-
19.
4.1 Input signal
Fig -3 is the plot of the cough input of a 53 old male, who is
diagnosis in covid-19.
Fig -3: Input signal for covid 19 positive
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 05 | May 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 2013
Fig -4: Input signal for covid 19 negative
4.2 Output for Mel filter bank
The final step to computing filter banks is applying
triangular filters, generally 40 filters, nfilter=40 on a Mel-
scale to the facility spectrum to extract frequencybands. Mel
scale accustomed convert between Hertz (f) and Mel (m)
using the subsequent equations:
f= 700(10m/2595-1)
Each filter within the filter bank is triangular having a
response of 1 at the center frequency and reduce linearly
towards zero until it reaches the middle frequencies of the
two adjacent filters wherever the response is 0, as shown
during this Fig -5
Fig -5: Output for Mel filter bank
4.3 PERFORMANCE METRICS:
Performance metrices are outlined as figures and
information representative of an organization’s actions,
abilities, and overall quality. Performance metrics will vary
significantly once whenviewedthroughcompletelydifferent
industries. Performance metrics are integral to an
organization’s success.
4.3.1 Confusion Matrix
The confusion matrix is an m x m matrix. m is that the no of
variables concerned. Diagonal parts represent the true
values and false values are expressedby non-diagonal parts.
There are four parameters Truepositive,Truenegative,false
positive, false negative.
4.3.2 Accuracy
Accuracy is decided as a magnitude relation of the events
properly classified to the whole events.
Accuracy= TP+TN/TP+TN+FP+FN
4.3.3 Sensitivity
Sensitivity measures the degree of completely classified
positive event.
Sensitivity= TP/TP+FN
4.3.4 Precision
Precision is decided because the magnitude relation of
range the amount of quality of positive samples properly
known to the whole number of positive samples either
properly or incorrectly.
Precision=TP/TP+FP.
4.3.5 F-score
It is the common of all recall (sensitivity) and accuracy.
F-score=2*((precision*Recall)/ (precision + Recall)).
Table -1: Performance evaluation report
From Table -1 it is inferred that the performance
measures using Modified MFCC are better than Mel
frequency cepstral coefficient.
This is graphical representation of performance metrics
comparison of MFCC and Modified MFCC
Chart -1: Performance metrics comparison of MFCC
and Modified MFCC
Performance Metrics MFCC Modified MFCC
Accuracy 0.6429 0.8846
Sensitivity 0.2857 0.8846
Specificity 0.64285 0.8846
Precision 0.79165 0.90625
F-score 0.5906 0.8696
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0.8
0.9
1
Accuracy Sensitivity Specificity Precision Fscore
MFCC Modified MFCC
Fig -3 is the input of a 43 years old normal man.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 05 | May 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 2014
Instead ofMel frequencycepstral coefficientusing(MFCC)
using Discrete FourierTransform(DFT)here modifiedMFCC
with Discrete wavelet transform (DWT) is used to get 88. %
Accuracy. This accuracy is 20% better than MFCCusingDFT.
5.CONCLUSIONS
Sound recordings of cough events contain prognosticative
information with relevancy the identification of COVID-19
positive cases from a forced-coughrecordings,together with
100% of symptomless, at primarily no cost. KNN classifier
methods revealed a complex structure for the dynamic time
deformation distance between the audio signal clusters.
However, there are distribution patterns within the signal
space with enough structure on change KNN classifier at
high performance to spot COVID-19 positive cases.
The result conferred here should be thought about baseline
since they were obtained directly from the rawaudiosignals
of dataset, for classifying a replacement sample signal, a
feature vector is built by computing the dissimilarities
between the new signal and training set paradigm.
Then, the classifier is applied to the feature vector to get the
expected class. There is potential to boost the
characterization and the classification result obtained,
together with an additional comprehensive analysis of the
ways. These should be aspects to be thought about in future
studies.
REFERENCES
[1] L. Li et al., “Using artificial intelligence to detect
COVID-19 and community acquired pneumonia
based pulmonary CT: Evaluation of the diagnostic
accuracy”, Radiology, Vol.296, no.2, pp. E65-E71,
Aug. 2020.
[2] X. Mei et al., “Artificial intelligence-enabled rapid
diagnosis of patients with COVID-19,” Nature Med.,
vol 26, pp.1224-1228,2020
[3] A. Imran et al., “AI4COVID-19: AI enabled
preliminary diagnosis for COVID-19 from cough
samples via an app,”2020, ArXiv :2004.01275.
[4] G. Botha et al., “Detection of tuberculosis by
automatic cough sound analysis,” Physiological
Meas., vol. 39, no. 4, 2018, Art. no. 045005.
[5] A. Windmon et al., “Tussis watch: A smartphone
system to identify cough episodes as early
symptoms of chronic obstructive pulmonary
disease and congestive heart failure,” IEEE J.
Biomed. Health In format., vol. 23, no. 4, pp. 1566–
1573, Jul. 2019.
[6] C. Pham, “Mob cough: Real-time cough detection
and monitoring using low-cost mobile devices,” in
Proc. Asian Conf. Intel. Inf. Database Syst., 2016, pp.
300–309.
[7] U.R. Abeyratne, V. Swanker, A. Satyarthi, and R.
Triasih, “Cough sound analysis can rapidly
diagnose childhoodpneumonia,”Ann. Biomed. Eng.,
vol. 41, no. 11, pp. 2448–2462, 2013.
[8] R.X.A. Pramono, S. A. Imtiaz, and E. Rodriguez-
Villegas, “A Cough based algorithm for automatic
diagnosis of pertussis,” vol. 11, no. 9, 2016.
[9] S.T. Moein, S.M. Hashemian, B. Mansour Afshar, A.
Khorram Tousi, P. Tamaris, and R.L. Doty, “Smell
dysfunction: AbiomarkerforCOVID-19,”in
International Forum of Allergy and Rhinology.
Hoboken, NJ, USA: Wiley Online Library, 2020
[10] T.T.T.F. Quartier and J. S. Palmer, “A framework for
biomarkers of COVID-19 based on coordination of
speech-production subsystems,” IEEE Open J. Eng.
Med. Biol., vol. 1, pp. 203–206, 2020.
[11] T. Higginbottom and J. Payne, “Glottisnarrowingin
lung disease,” Amer. Rev. Respiratory Disease, vol.
125, no. 6, pp. 746–750, 1982

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AUTOMATIC COVID DETECTION USING COUGH SIGNAL ANALYSIS

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 05 | May 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 2011 AUTOMATIC COVID DETECTION USING COUGH SIGNAL ANALYSIS P. SELVAVENI1, G. RENISHA2 1Student, Dept of ECE, GCE-Tirunelveli, Tamil Nadu, India 2Assistant Professor, Dept of ECE, GCE-Tirunelveli, Tamil Nadu, India ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - Remote observation and measurements are valuable tools for medical applications and they are notably necessary inside the context of pandemic outbreaks similarto this COVID-19. COVID-19 subjects particularly together with symptomless, can be accurately discriminated from forced cough mobile transportable recordings. The information consists of a set of audiosamplescollected fromVirufy/clinical data. Cough recordings are remodeled with Modified Mel frequency cepstral coefficient (MFCC) and inputted into a k- Nearest neighbor (k-NN) classifier during this technique was used to obtain models identifying cough with high performance classifiers were obtained for many of them, including COVD-19. These results are preliminary and there’s potential to enhance, as there have been obtained from dataset. In this technique free, invisible, anytime, accessibleby anyone, no laboratory testing is needed, no cost, instantly distributable, large scale COVID-19 symptomless screening tool to reinforce practical use cases can be daily screening of students, workers, and public as schools, jobs, and transport reopen, or pool testing to quickly alert of outbreaks in teams. COVID-19 positive samples in our dataset are haphazardly choose the quality of COVID 19 negative subjects for a balanced distribution. The topic forced- cough audios and diagnostic results were used to train and validate the COVID- 19 discriminator. Key Words: Covid-19,MFCC,DFT,k-NN,MODIFIEDMFCC, DWT, speech recognition, 1. INTRODUCTION Coronavirus disease 2019 (COVID-19) is a highlycontagious viral illness caused by severe acute respiratory syndrome SARAS-CoV-2. A Worldwide coordinated effortis requiredto prevent the further spread of the virus. A deadly disease defined as “occurring as over wide geographical region and affecting an exceptionally high proportion of thepopulation. The virus has inflicted billion of lives across the world in some ways e.g.: physically, psychologically, socially. Compared to other diseases COVID-19 has had: significantly higher transmissibility; worst post recovery; frequent mutation; resulting in higher mortalities and uncontrolled virulence. The clinical manifestations of this particularvirus have exhibited deleterious impacts on systems apart from the respiratory systems. In fact, across the world, outbreaks are threatening a second wave, which within the Spanish flu was far more dangerous than the primary one. These outbreaks are very hard to contain with current testing approaches are unless region wide confinement measures were sustained. This partly because limitations of current viral and serology tests and also the lack of complementary pre-screening methods to efficiently select who should be tested. They are expensive to creating thepriceoftestingthe entire country day by day impossible. COVID-19 symptoms may range from none to deadly. Severe illness is more likely in elderly patients andthose withcertainunderlyingmedical conditions. COVID-19 is airborne,spreadvia aircontainment by microscope virions. Then risk of infection is highest among people in close proximity, but can occur over long distances, particularly indoors in poorly ventilated areas. transmission rarely occurs via containmentsurfaceorfluids. Infected peoples are typically contagious for 10 days, often beginning before or without symptoms. 1.1 Coronavirus Coronavirus is a large family of viruses that causeillness like respiratorydiseasesorgastrointestinal diseases.Respiratory diseases can range from the respiratory disease to more severe diseases e.g.  Middle East Respiratory Syndrome (MERS-CoV)  Severe Acute Respiratory Syndrome (SARS-CoV) A completely unique corona virus may be a new strain that has not been identifiedinhumanspreviously.Oncescientists determine exactly what coronavirus it is, the furnish it name as a within the case of COVID-19, the viruscausingitisSARS- CoV-2). Fig -1: Microscopic picture of coronavirus
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 05 | May 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 2012 Coronaviruses got their name from the way thatthey appear under a microscope. The virus consists of surrounded by an envelope with protein spikes. The gives it the look of a crown. The word corona means “crown’” in Latin. Coronavirus are transmitted between animals and humans. It's been determined that MERS-COV was transmitted from dromedary camels to humans and SARS from civet cat to humans. The source of SARS-COV2 is yet to be determined, but investigations are ongoing to spot the zoonotic source to the outbreak. 2. DATABASE USED Recording was available in various browser and devices (virufy/clinical data). data was anonymized before being collected on our secure samples were saved without compression in WAV format. Samples that had no audio content were removed. Segmentation was performedonthe cough recordings used to train and test. COVID- 19 positive samples in our dataset are randomly selected the identical range of COVID 19 negative subjects for a balanced distribution. The topic forced- cough audios and diagnostic results were used to train and validate the COVID-19 discriminator. 3.FEATURE EXTRACTION Feature extraction is an important and basic step of speech recognition. It is associate in nursing exceptional kind of property decreases technique that is used to reducethedata which is intensive to be ready by calculation. In speech recognition, Feature extraction is that the way towards holding valuable data of the signal whereas eliminating of repetitive and undesirable data. It’s the parameterization of the speech signal. It is the procedure of fixing the signal to digital type, measuring some imperative character of the signal, for example, energyandfrequencyresponses. Speech recognition could be a supervised learning task. In speech recognition problem input will be the audio signal and we got to predict the text from the audio signals. take the raw audio signal as input to our model be as a result of there will be a lot of noise within the audio signal. It is determined that extracting options from the audio signal and using it as input to the bottom model can manufacture much better performance than directly considering raw audio signal as input MFCC is that the wide used technique for extracting the options from the audio signal. Instead of Mel frequency cepstral coefficient using (MFCC) using Discrete Fourier Transform (DFT) here modified MFCC withDiscrete wavelet transform (DWT) is used to get better accuracy then MFCC using DFT. Fig -2: Block diagram of modified MFCC 4.RESULTS Recording was out there in numerous browser and devices (virufy/clinical data). data was anonymized before being collected on our secure samples were saved without compression in WAV format. Samples that had no audio content were removed. Segmentation was performedonthe cough recordings used to train and check. COVID-19 positive samples in our dataset are randomly selected the same number of COVID 19 negative subjects for a balanced distribution. The topic forced- cough audios and diagnostic results were used totrainandvalidatethe COVID- 19. 4.1 Input signal Fig -3 is the plot of the cough input of a 53 old male, who is diagnosis in covid-19. Fig -3: Input signal for covid 19 positive
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 05 | May 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 2013 Fig -4: Input signal for covid 19 negative 4.2 Output for Mel filter bank The final step to computing filter banks is applying triangular filters, generally 40 filters, nfilter=40 on a Mel- scale to the facility spectrum to extract frequencybands. Mel scale accustomed convert between Hertz (f) and Mel (m) using the subsequent equations: f= 700(10m/2595-1) Each filter within the filter bank is triangular having a response of 1 at the center frequency and reduce linearly towards zero until it reaches the middle frequencies of the two adjacent filters wherever the response is 0, as shown during this Fig -5 Fig -5: Output for Mel filter bank 4.3 PERFORMANCE METRICS: Performance metrices are outlined as figures and information representative of an organization’s actions, abilities, and overall quality. Performance metrics will vary significantly once whenviewedthroughcompletelydifferent industries. Performance metrics are integral to an organization’s success. 4.3.1 Confusion Matrix The confusion matrix is an m x m matrix. m is that the no of variables concerned. Diagonal parts represent the true values and false values are expressedby non-diagonal parts. There are four parameters Truepositive,Truenegative,false positive, false negative. 4.3.2 Accuracy Accuracy is decided as a magnitude relation of the events properly classified to the whole events. Accuracy= TP+TN/TP+TN+FP+FN 4.3.3 Sensitivity Sensitivity measures the degree of completely classified positive event. Sensitivity= TP/TP+FN 4.3.4 Precision Precision is decided because the magnitude relation of range the amount of quality of positive samples properly known to the whole number of positive samples either properly or incorrectly. Precision=TP/TP+FP. 4.3.5 F-score It is the common of all recall (sensitivity) and accuracy. F-score=2*((precision*Recall)/ (precision + Recall)). Table -1: Performance evaluation report From Table -1 it is inferred that the performance measures using Modified MFCC are better than Mel frequency cepstral coefficient. This is graphical representation of performance metrics comparison of MFCC and Modified MFCC Chart -1: Performance metrics comparison of MFCC and Modified MFCC Performance Metrics MFCC Modified MFCC Accuracy 0.6429 0.8846 Sensitivity 0.2857 0.8846 Specificity 0.64285 0.8846 Precision 0.79165 0.90625 F-score 0.5906 0.8696 0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1 Accuracy Sensitivity Specificity Precision Fscore MFCC Modified MFCC Fig -3 is the input of a 43 years old normal man.
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 05 | May 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 2014 Instead ofMel frequencycepstral coefficientusing(MFCC) using Discrete FourierTransform(DFT)here modifiedMFCC with Discrete wavelet transform (DWT) is used to get 88. % Accuracy. This accuracy is 20% better than MFCCusingDFT. 5.CONCLUSIONS Sound recordings of cough events contain prognosticative information with relevancy the identification of COVID-19 positive cases from a forced-coughrecordings,together with 100% of symptomless, at primarily no cost. KNN classifier methods revealed a complex structure for the dynamic time deformation distance between the audio signal clusters. However, there are distribution patterns within the signal space with enough structure on change KNN classifier at high performance to spot COVID-19 positive cases. The result conferred here should be thought about baseline since they were obtained directly from the rawaudiosignals of dataset, for classifying a replacement sample signal, a feature vector is built by computing the dissimilarities between the new signal and training set paradigm. Then, the classifier is applied to the feature vector to get the expected class. There is potential to boost the characterization and the classification result obtained, together with an additional comprehensive analysis of the ways. These should be aspects to be thought about in future studies. REFERENCES [1] L. Li et al., “Using artificial intelligence to detect COVID-19 and community acquired pneumonia based pulmonary CT: Evaluation of the diagnostic accuracy”, Radiology, Vol.296, no.2, pp. E65-E71, Aug. 2020. [2] X. Mei et al., “Artificial intelligence-enabled rapid diagnosis of patients with COVID-19,” Nature Med., vol 26, pp.1224-1228,2020 [3] A. Imran et al., “AI4COVID-19: AI enabled preliminary diagnosis for COVID-19 from cough samples via an app,”2020, ArXiv :2004.01275. [4] G. Botha et al., “Detection of tuberculosis by automatic cough sound analysis,” Physiological Meas., vol. 39, no. 4, 2018, Art. no. 045005. [5] A. Windmon et al., “Tussis watch: A smartphone system to identify cough episodes as early symptoms of chronic obstructive pulmonary disease and congestive heart failure,” IEEE J. Biomed. Health In format., vol. 23, no. 4, pp. 1566– 1573, Jul. 2019. [6] C. Pham, “Mob cough: Real-time cough detection and monitoring using low-cost mobile devices,” in Proc. Asian Conf. Intel. Inf. Database Syst., 2016, pp. 300–309. [7] U.R. Abeyratne, V. Swanker, A. Satyarthi, and R. Triasih, “Cough sound analysis can rapidly diagnose childhoodpneumonia,”Ann. Biomed. Eng., vol. 41, no. 11, pp. 2448–2462, 2013. [8] R.X.A. Pramono, S. A. Imtiaz, and E. Rodriguez- Villegas, “A Cough based algorithm for automatic diagnosis of pertussis,” vol. 11, no. 9, 2016. [9] S.T. Moein, S.M. Hashemian, B. Mansour Afshar, A. Khorram Tousi, P. Tamaris, and R.L. Doty, “Smell dysfunction: AbiomarkerforCOVID-19,”in International Forum of Allergy and Rhinology. Hoboken, NJ, USA: Wiley Online Library, 2020 [10] T.T.T.F. Quartier and J. S. Palmer, “A framework for biomarkers of COVID-19 based on coordination of speech-production subsystems,” IEEE Open J. Eng. Med. Biol., vol. 1, pp. 203–206, 2020. [11] T. Higginbottom and J. Payne, “Glottisnarrowingin lung disease,” Amer. Rev. Respiratory Disease, vol. 125, no. 6, pp. 746–750, 1982