We have come up with ‘Best Healthcare Startups to Watch for 2019’ issue in which we have introduced the leading organizations that are spearheading the healthcare field with their innovative services and solutions.

1. 2019, Vol.7, Issue-1
www.insightscare.com
BEST
HEALTHCARE
STARTUPS
TO WATCH FOR 2019

4. Artificial
Intelligence:
A Gateway to
Enhanced
Healthcare

5. Wouldn’t it be amazing if you are reminded of your medications by a virtual assisting nurse or the virtual
assistant, a helper aiding you in your daily routine? Today, this is easily achieved by implementing AI and
robotics. While AI is booming across various industries, in healthcare, its huge impact promises to be
genuinely life-transforming. Right from clinical research to hospital care, insurance and drug development, healthcare
is undergoing a paradigm shift with AI and has evolved to reduce expenditure and improving patient outcomes.
One of AI’s biggest potential benefits is to assist people stay healthy so they don’t need a doctor, not at least as often
as they might be visiting already. Technology applications and apps not only encourage healthier behavior in
individuals but put consumers in control of own well-being.
With AI, the healthcare professionals are gaining a deep understanding of the day-to-day patterns and needs of the
people at the tip of their fingers, which in turn provides better feedback, guidance, and support for staying healthy.
This advanced technology is already being used to detect major diseases, like cancer, more precisely and that too, in
the early stages. Adding to this/Additionally, the implementation of AI is enabling review and translation of
mammograms with over thirty times faster with 99% accuracy, hence reducing the need for biopsies.
The advancement doesn’t stop here. The medical devices and consumer wearable with the AI touch can be used to
manage an early-stage heart disease allowing doctors to monitor and rectify potentially life-threatening diseases at an
early stage.
By observing the whole scenario, there is no doubt, that AI holds huge potential to transform end of life care. Thus, it
helps others remain independent for longer without the need for hospitalization. AI combined with the advancements
in humanoid design are enabling robots to cross the borders of ‘communications’ and other social interactions with
people to keep the old minds sharp.

6. 16
Healthy Mothers,
Healthy Babies
BabyMed
22
Clinical Performance
Solutions for High-performing
Cardiovascular Centers
Biome Analytics
10
Helping People Live a Longer
Healthier Tomorrow
Acorn Biolabs
CXO Standpoint
20
CONTENTS
14
5 cutting-edge
trends of Healthcare
Startups
Tech-trendEmpowering Patients
through Technology
Tech-spotlight
ARTICLE

7. 26
Enhancing Communication,
Building Relationships,
and Revamping the
Care Experience
Conversa Health
30
A Leading Organization
Developing Technology for
Breast Cancer Screening
Micrima
34
Offering Precise User-
friendly Skin-based
Drug Delivery Technologies
Nemaura Pharma
38
Revolutionizing Healthcare
with Deep Learning
Transformative AI

8. Dynamic Startups
Re-transforming
Healthcare Space
STARTUPS
HEALTHCARE
TO WATCH FOR 2019
Best
The ability of advanced technologies in solving a wide range of issues for patients, hospitals, and the
healthcare industry is the impulse behind its sudden rising implementation in healthcare. However,
healthcare providers often get stuck in few ambiguous situations regarding the enhancement of patient
care, helping people in this competitive world, along with providing cost-effective solutions.
Considering these issues, most of the organizations are implementing advanced technology. These organizations are
increasingly looking towards evolved real-time analytics such as AI and Machine Learning to cover the processing
and data delivery. Implementation of real-time analytics assists physicians to detect and rectify diseases quickly,
reducing time-to-time treatment and care costs. This eventually leads to better patient care and outcomes.
With this regard, we have come up with ‘Best Healthcare Startups to Watch for 2019’ issue in which we have
introduced the leading organizations that are spearheading the healthcare field with their innovative services and
solutions.
In our issue ‘Best Healthcare Startups to Watch for 2019’, we have introduced the leading and dynamic startups
that are spearheading the healthcare space with their astounding services and solutions. We have presented, Acorn
Biolabs, a healthcare technology company focused on delivering easy, affordable and non-invasive live cell
collection, analysis and cryopreservation service; BabyMed which is an integrated and innovative mobile health
platform that provides easy and affordable access to reliable maternal and child health care information and
services; Biome Analytics which offers cardiovascular performance solutions that combine machine learning
technologies with human-driven insights to improve clinical and financial performance; Conversa Health which is
a clinically-intelligent conversation platform helps healthcare organizations deliver smart, automated, patient
conversation experiences that are patient profile driven and lead to more meaningful patient relationships, better
population management, improved care coordination, and quality outcomes; Micrima, the leading company that
helps to detect breast cancer at an early stage with its innovative product; Nemaura Medical, a private
pharmaceutical company that offers apt, reliable, and minimally invasive skin-based drug delivery technologies;
Transformative AI which is the leading start-up that blends AI and novel analysis techniques employed at CERN
and provides distinctive solutions to the clients; Soul Insole whose bio-mechanically designed shape of the Shoe
Bubble effectively redistributes pressure evenly across the foot to relieve pressure from the heel and forefoot;
Neurotrack that uses clinically proven science to help you assess and improve your memory over time; and
Lucidium Health which enhances Healthcare for people at large through improving the current research processes
by using AI-enabled, secure and intuitive platform to connect individuals & research organizations.
We have also encompassed CXO article ‘Empowering Patients through Technology’ written by Dimas
Francisco Silva Jr, Medcloud Founder and CEO.
Our in-house editors have also scripted amazing article on ‘5 Cutting-edge Trends of Healthcare’ which would
shed some light on tech-advancements.
So, flip through the pages of the magazine and enjoy the journeys of Startups!

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July, 2019
Editor-in-Chief Pooja M. Bansal
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Reprint rights remain solely with Insights Success.
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SME-SMO Executives Manoj, Gemson, Uma
Research Analyst Eric Smith
Circulation Manager Tanaji

12. BIOLABS: HELPING PEOPLE LIVE A LONGER HEALTHIER TOMORROW
Dr. Drew Taylor
CEO & Co-founder
10 |July 2019|

13. corn Biolabs is a healthcare technology company
Afocused on giving every human being the best
chance to experience more healthy years with its
easy, affordable and non-invasive live cell collection,
analysis, and cryopreservation service.
Acorn provides a live cell collection service and a
subscription storage model that keeps consumer’s live cells
cryopreserved as a healthcare resource for as long as they
need it. Preserving live cells also unlocks a vast world of
data and genetics on an ongoing basis so that consumers
have in Acorn a healthcare partner for life. Acorn also offers
live cell collection, cryopreservation and genetic analysis
services.
Why Acorn Biolabs?
• Acorn Freezes the Clock On Your Cells.
The urgency around collecting, preserving and storing
youthful cells for future use is real and freezing the clock
on your cells today will ensure you can leverage them later
when you need them most. Acorn preserves your youngest,
best cells today to ready you for the future of regenerative
medicine tomorrow.
• Acorn Unlocks the Future of Regenerative Medicine for
Everyone.
Till now, stem cell collection has been expensive, invasive
and painful through bone marrow harvesting, liposuction,
blood draws and umbilical cord banking. More recent DNA
home testing kits only captured dead cells from saliva that
are unusable in cell therapy. Acorn gives a live cell
collection that is accessible, affordable and viable for
regenerative medicine through the simple non-invasive
plucking of a few hairs from your head. This makes the
future of regenerative medicine, genetics and powerful stem
cell therapy accessible to everyone.
About the Passionate and Sporty Leader
Dr. Drew Taylor is the Co-founder and Chief Executive
Officer at Acorn Biolabs. Being a Biologist and a former
professional athlete, Drew has charted his path across
molecular cell biology, science and baseball with steadfast
passion over his career. He completed an undergraduate
degree in Biology at the University of Michigan and a
Masters from the same school in Molecular, Cellular, and
Developmental Biology. He also holds a PhD with the
University of Toronto in Biomedical Engineering. Drew has
enjoyed a successful career in professional minor league
baseball as a pitcher for both the Toronto Blue Jays and the
Philadelphia Phillies, charting parallel paths across both
professional sports and science.
Prior to joining Acorn, Drew spent several years as Chief
Science Officer at Epic Capital Management working
across the flourishing biotech start-up community. Also,
prior to that he was a part of the Mount Sinai Hospital
Bioengineering of Skeletal Tissues Team. He has been
widely published across international medical journals with
specific focus on tissue engineering and sports medicine.
Story behind the Inception
It all started when Dr. Drew met Steven Ten Holder and
Patrick Pumputis, the other Co-founders of Acorn Biolabs,
while Drew was the Chief Science Officer with Epic
Capital. Prior to Epic Capital he had been involved with a
medical team researching using cell therapy and
regenerative medicine for orthopedics. Seeing first-hand
how older cells were not as successful as younger cells in
replacing cartilage led him to feel there had to be a solution.
Meeting Patrick and Steven in many ways felt very much
like serendipity as they compared notes. Together they
quickly realized that Steven, who had been researching cell
division and how technology could be leveraged in
longevity; combined with Patrick’s research focus on cell
nutrition and preservation; with Drew’s background in
emerging health technologies and medical cell therapy. It
was all together was a winning combination to create
something that could truly change the way people thought
about personal healthcare.
Major Challenges on the Road
The regenerative medicine space and all the advancements
around CRISPR, iPSCs, genomics and cell and gene
therapy is complicated. Also, consumers haven’t really
gotten their head fully around the magnitude of the impact
these advancements are going to have in their lifetime.
Acorn is more concerned about the fast-evolving science
which is moving faster than consumer understanding of the
value of their cells. The company believes that one day
science will have fully commercialized cell and gene
therapy and there will be generations of consumers too old
to benefit.
“Acorn has a significant role to play in educating on this
space and preparing people for the future. No one thought
that today we would be planning for self-driving cars, or
|July 2019| 11
STARTUPS
HEALTHCARE
TO WATCH FOR 2019
Best

14. ‘‘
Consumers trust us
with their cells which as
scientists we believe are
an invaluable resource
that will unlock the future
their personalized healthcare
12 |July 2019|

16. EMPOWERING
Patients
through
Technologyhe growing use of
Tcommunication applications
has facilitated the adherence
not only of technology focused on
social interactions. Health
professionals are much more familiar
with the use of technology in medical
practice. Specialized health
applications and platforms now take
advantage of a global digital model
that has come to stay.
For some years, information
technology managers were asked about
the adherence of health professionals
in the implementation of new projects
involving technology. Now, through a
much more favorable scenario,
managers and administrators of clinics
and hospitals make much safer and
more favorable decisions to such
projects.
Terms like “Instagram of Medicine”
and “Facebook of Physicians” are
increasing. Proximity to such
applications provides familiarity with
an already consolidated interaction and
navigation model, preserved in due
proportions.
The forecasts for the area of
technology for health, reaffirm once
again an increasingly favorable
scenario for engagement and
collaboration, through the management
and sharing of medical data and
records.
Smartphones and tablets tend to be
more and more essential tools in
everyday life when it comes to health
thanks to applications that provide new
ways of accessing information and
practicing medicine.
With the consolidation of the use of
technology as a tool in daily medical
practice, clinics and laboratories
specialized in diagnostics have a
unique opportunity for relationship and
communication with their patients,
allied to the best and most favorable
moment for the use of technology in
the health area.
Patient-centered Care
Patients wish to get involved in their
health decision-making process, and
those who are involved as decision
makers in their care tend to be
healthier and have better outcomes.
By patient’s journey we understand the
whole process that involves from the
moment the patient perceives some
symptom or something different in his
body, until the completion of the care.
Although the patient’s journey
corresponds to all the experience he
has from beginning to end in his clinic,
the post consultation period ends up
being an essential pillar in the
construction of this experience. This is
because it is at this moment that the
patient is able to evaluate the way it
has been treated, even analyzing the
possibility of a return if he or she needs
care in the future.
By following the patient’s journey, you
need to think of a model that meets
your individual needs and
expectations. Therefore, it is possible
to understand the need for
customization, since no patient is the
same as the other.
14 |July 2019|

17. Dimas Francisco Silva Jr, Medcloud Founder
and CEO, a Health entrepreneur, believes in the
power of centralized data for decentralized care.
He has mission to accelerate the transition of
imaging centers to the Cloud and is passionate
about Patient Experience, A.I and Medical
Networks. Medcloud is an All-In-One platform
for diagnostics management, EHR RIS, DICOM
Viewer, Drive Storage, Portal of Diagnostics,
100% Web frrom Diagnostic Imaging Centers,
Telemedicine projects, and Dental Companies to
Cardiology Centers. A common challenge is
managing the information of patients and their
exams, in a secure and reliable way. More than
just increasing productivity, Medcloud offers
timely and uncomplicated solutions for the
entire life cycle in healthcare data management.
Chronic patients, for example, face
somewhat different journeys. By
necessity of monitoring, these people
need to have a much greater control of
their medical information.
Someone who needs to visit their
doctor regularly, gets stuck to
numerous images and physical reports.
When a diagnostic center offers other
options, such as outcome portals or
applications for storing these exams, it
engages its patients.
A person who goes from a reality of
having to organize, store and carry to
having all the information gathered
from a click gains empowerment.
By fostering digital services that take
advantage of new, mobile Internet
access, providers are beyond engaging
their audience, facilitating the
Physician-Patient relationship, since
such devices have revolutionized the
way we communicate.
It is also important to consider the
whole group of family and friends
around the patient. Often, the caregiver
is not active. So there is the concept of
engaging people to consider everyone
around the patient and take a more
active role. It is important to include all
these subjects.
By bringing the diagnostic industry
closer to the digital trends of the
market, mobile devices like
smarthphones and tablets appear as the
first choice of relationship. In addition,
offer even more options to put the
patient in control, such as scheduling
appointments and exams, sending
some documents, and small tasks that
facilitates their daily lives, approaches
the patient.
Technology plays a key role in
strengthening the doctor-patient
relationship. Providing channels of
communication and more practical
ways for the patient to be able to ask
questions or, eventually, to ask for help
from their specialists also puts the
patient in a more active role.
Leave the patient in the position of
control of their own health. Giving
flexibility, convenience and practicality
in the age of the internet and mobile
devices is not a differential, it is the
minimum that any clinic or hospital
can offer its clients.
ABOUT THE AUTHOR
Dimas Francisco Silva Jr
Founder and CEO
|July 2019| 15
Tech-spotlight

18. BabyMedHealthy Mothers, Healthy Babies
BabyMed is an integrated and innovative mobile
health platform that provides easy and affordable
access to reliable maternal and child health care
information and services. The platform provides important
weekly health messages to pregnant women, mothers with
newborn babies, and their family members. It comprises of
SMS text messages, voice messages, Interactive Voice
Response(IVR) onwebinformationportal.
The major aim of BabyMed is to empower pregnant women
and their partners to take the steps necessary for a healthy
pregnancy and safe delivery. The SMS text and voice
messaging service integrates all the healthy pregnancy and
safe motherhood topics under one platform. This includes
early and complete ANC attendance, malaria prevention, the
prevention of mother to child transmission of HIV (PMTCT),
individualbirthplanning,andsafedelivery.
Outstanding Mission
In African nations (Kenya in particular), 6000 women die
every year due to preventable pregnancy or childbirth
problems. The doctor to patient ratio in Kenya is 1:17,000
(WHO recommends 1:1000). Due to a lack of collective
community knowledge for safe and healthy pregnancy and
75% of the Kenya population living in the rural areas,
pregnant women and mothers may delay seeking care or
takingappropriatepreventativeorcurativeaction.
To resolve this situation, BabyMed is on a mission to save the
lives of the 6000 pregnant women, guardians of young
children, and women of child-bearing age who die every day
in Kenya due to preventable pregnancy or childbirth
problems.
About theCompassionate Leader
Bryan Okello, the Founder/CEO is a highly motivated,
passionate, and result oriented professional. He has a keen
interest on engaging, developing, and impacting communities
through information communication technologies to deliver
highly effective and creative solutions to business and
technology challenges. Bryan has been in accounting, finance
and business information technology, hands-on software
training,andwebdevelopmentformorethantenyears.
Bryan is passionate about transforming maternal and child
health care in Kenya and in Africa through the utilization of
mobile and digital technology. His inspiration for coming up
with BabyMed is the desire to see a world where no woman
should die while bringing life to this world and every child
bornshouldgrow torealizeitsfullpotential.
Uniqueness atitsBest
BabyMed provides age and stage-based messages aligned
with global best practices, empowering women to make the
best decisions for themselves and their families.The company
leverages the high number of mobile devices to inform and
empower mothers to adopt healthy behaviors and to access
maternal and child health services. With increased access to
high quality, relevant local health information, mothers and
families would demonstrate improved health-seeking and
preventative behaviors, including uptake of antenatal care,
early care-seeking in response to childhood illness, hand
washing, cord care, etc., that should ultimately contribute to
improvedmaternalandchildsurvival.
Besides, BabyMed’s SMS and audio messages are targeted to
awoman’s stageofpregnancyortheageofherchildso that
We wish to create a world
where no woman should die
while bringing life to this world
and every child born should
grow to realize its full potential
““
““
16 |July 2019|

19. Bryan Okello
Founder & CEO
|July 2019| 17
STARTUPS
HEALTHCARE
TO WATCH FOR 2019
Best

20. the information reflects exactly what she is experiencing at a
particular time. This helps to build an emotional connection
with the mother and a sense of trust, making it more likely that
she will be receptive to messages that encourage changes in
behavior. The messaging program accompanies each mother
on her journey of learning and discovery and acts as a step-by-
step guide to a healthy pregnancy and a healthy baby.
BabyMed provides ICT consultancy, innovative solutions for
theeducationsector,andwebdesignanddevelopment.
Talking about social activities, the company conducts Twitter
chats on maternal and child health issues and also organizes
marathons (Beyond Zero marathon) and walks targeted at
highlighting maternal and child health mortality. Not only
this, but BabyMed also advocates and promotes exclusive
breastfeedingforchildrenaged0-6months.
Awards and Recognitions
• Top application in the health category in the Safari.com
appdeveloperchallenge
• Top Ten Finalist in the Women &Access to Health Call
for Initiatives! In April 2019, Bryan Okello was
shortlisted as one of the top ten finalists (the only finalist
from Africa) in Women & Access to Health Call for
Initiatives!OrganizedbytheWomen’s Forum.
• Publication of BabyMed’s story in the StartUp Health
Magazine
• Partnership with StartUp Health. In June 2016,
BabyMed was selected by StartUp Health to join its
Portfolio of Digital Health Companies working to
transform Health Care with Bryan Okello becoming the
First Healthcare Transformer from Africa to join the
academy. This was a very important milestone for the
company because guidance from StartUp Health and
access to its networks will be crucial in accelerating our
growth. StartUp Health is leading a global movement to
transform health by organizing and investing in the
world’s largest community of Healthcare Transformers.
With the coaching, support and promotion from StartUp
Health Academy, BabyMed is now well placed to
transformmaternalandchildhealthcareinKenya.
Three-pieceAdvice
BabyMed advices the budding entrepreneurs in the healthcare
space to Anticipate Potential Snags i.e. every meeting is an
opportunity to develop and grow. No doubt, there will be
some mistakes along the way, but if they can’t be avoided, one
shouldrememberthatlearningisacontinuousprocess.
Secondly, it suggests to Think Small, At First.As the world of
healthcare is very much regimented, innovation may be
something completely world-changing in time, but at first,
one should focus on getting it adopted on a small-scale basis
whereitseffectivenesscanbeproven.
Lastly, it recommends to Get Out There because the company
believes that spending as much possible time in the exact
environment the product will be used in, will give an idea of
thenuancesandpotentialissues thatwillcomewithitsuse.
StrategicPlanforaGloriousFuture
• Signuponemillionusers
• Translation of messages to local languages such as
Kiswahili,Kikuyu,Luo,Kamba,Kalenjin
• Set up BabyMed Social: An interactive social network
where mothers can read articles and have a conversation
withtheirpeers
• Set up BabyMed on USSD in order to offer weekly two
interactive quizzes tailored to mothers’gestational stage or
theageoftheirbaby
• Expand to other east African countries such as Tanzania,
Uganda, and Rwanda. Institute a monthly block
knowledge sharing sessions that bring together all
expectant mothers registered at a facility for information
sharinginagroup.
• Set up Maternal Health Corners with partnering health
facilities made up of a set of computers that have been
programmed with content (audio, video, and text) for the
benefitofhealthworkers
What’s nextintheStore?
BabyMed would be launching its android mobile app as well
as its redesigned website. The company would be signing up
partnership agreement with Uridu.org. URIDU is a non-
profit, non-partisan organization that empowers rural women
in developing and emerging countries.Also, discussions are a
in an advanced stage to partner with ‘Africa’s Talking’ to
facilitatescaleupofitsmobileservicetoallpartsofKenya.
18 |July 2019|

22. 5HEALTHCARE
STARTUPS
ARTIFICIAL INTELLIGENCE
AI in medical technologies is doing miracles in the
healthcare industry. It can easily process huge data,
help in diagnosis and provide accurate results. AI
comeshandyasitspeedsuptheresearchandanalysis
of various processes including drug discovery and
gene cmodifica ons.
IOMT
Internet of Medical Things or in common language
health wearables are booming all over the world. Due
to its effec veness towards keeping oneself fit, it has
been on the top for a long me now. The most
beneficial part of IoMT is it can be connected through
variousmobileapps.
20 |July 2019|

23. TELEHEALTH
With evolving technology, healthcare has moved on
as well. With the help of various techniques, it has
now become possible for doctors, hospitals to
providetreatmenttopa entsremotely.
DATA ANALYSIS
Dataanalysisisnothingbutadigitalorganizerthatwill
also perform analysis processes like health records,
lab results, medical history, diagnosis history, and
many more. It has been saving precious me and
manpower.
VR/AR
Virtual Reality or Augmented Reality has already taken
over the technologies of all the sectors. But, specifically,
speaking about healthcare, it has been doing wonders.
From diagnosis to medical educa on, VR and AR have
helpedthissectorflourish.Ithasbeensaidtobeusefulin
providingtreatmenttoawiderangeofillness.
Tech-trend
|July 2019| 21

24. 22 |July 2019|
Biome Analytics
Clinical Performance Solutions for
High-performing Cardiovascular Centers
ardiovascular disease affects over 11% of the US
Cpopulation and is the leading cause of death for
both men and women. Hospitals and doctors
treating these patients face unprecedented challenges driven
by increasing volume, disruptive new procedures, greater
competition, and the transition to value-based care.
Successfully confronting and succeeding over these
challenges require providing clinical and administrative
teams access to trusted data and clinically and financially
relevant insights. But, because cardiovascular care is highly
nuanced, one-size-fits-all analytic solutions lack the
precision required to engage clinicians and cannot show
users how to improve. Internal analytic teams are stretched
thin, lacking deep expertise in the cardiovascular and cost
accounting domains, and struggle to stay au fait with
changing standards of care, best practice guidelines, and
reimbursement models. In an effort to help providers and
administrators solve these issues, Biome Analytics was
formed.
In 2013, a team of data scientists, engineers, and clinical
experts came together. They all had a common goal of
providing doctors and hospitals with the granular insights
necessary for improving care and lowering costs for over 27
million Americans with heart and vascular disease.
Stuart Jacobson, the CEO of Biome Analytics, founded
the company believing that if a common fact base for
performance management existed, doctors and hospitals
would self-optimize in delivering high-performance
cardiovascular care and excellent quality clinical care at the
lowest possible cost. “We specialize because
cardiovascular care is unique, sometimes variation makes
sense, and generalized tools and analytics have failed to
engage and align clinicians,” says Stuart.
What does Biome do?
Founded in San Francisco, California, Biome Analytics is a
cutting-edge leader in the digital healthcare space. The
company delivers a new generation of clinical performance
applications that bring hospitals and doctors together
around a trusted data source, clinically relevant
benchmarks, and actionable insight. The company was
established with the guiding principle- ‘Every clinician
wants to deliver the best possible care’. Secondly, it also
believes that ‘When the clinicians have trusted, actionable
insights, they will self-optimize.’
Our unique solutions
combine advanced analytic
techniques with human-
driven insights to help
hospitals and doctors at
leading heart centers be
their best
““
““

25. Stuart Jacobson
CEO
|July 2019| 23
STARTUPS
HEALTHCARE
TO WATCH FOR 2019
Best

26. 24 |July 2019|
Biome provides the ability to the hospitals and doctors to
seamlessly align around how to , eliminating expensive
guesswork around what specific actions will move the cost
needle, and providing clinicians the tool they need to show
exactly when care variation is necessary
Why Biome?
• Intelligent Variation
Biome has procedure-specific performance models that
seamlessly integrate hospital cost accounting and
clinical data. Its algorithm-based performance
assessment engine detects high-value clinical and
financial opportunities for clients. Biome delivers a
community-driven performance library, containing
clinical and financial benchmarks, models, and
performance improvement strategies.
• Cardiovascular Focus and Expertise
Biome’s applications enable hospitals to increase
contribution margins throughout the cardiovascular
service line. Clients rely on Biome’s experience to
evaluate the impact of evolving therapies, identify
vendor opportunities, and quicken time to value. Some
recent client successes include:
• $2 million cost savings opportunities identified within
60 days
• Average TAVR LOS reduced by 3 days
• Net-new 164 bed opening availability
• $1.7 million in cost misallocation identified
• Observed vs. Expected Mortality Decreased by 35.7%
• A Delivery Model Built for Speed and Quality
While analytic applications largely focus on IT
departments as the primary user, Biome focuses on
delivering analytic capabilities to the physicians and
administrators, without requiring users to become data
scientists. Additionally, Biome manages the full
engagement- from requesting and collecting data, to
creating the models, to delivering the insights. Users
can ask questions and get answers in record time.
Finally, with access to a library of over 200+
cardiovascular-specific analytics, clients can explore a
myriad of improvement opportunities in seconds,
instead of waiting for weeks for the internal teams to
create a new analytic.
Biome’s Unique Solution
Biome offers an end-to-end solution for cardiovascular
performance management; over 200 cardiovascular-specific
analytics that drives the insight into actionable root-cause
performance improvement opportunities. Analytic access is
provided to users via Tableau visualizations, and Biome’s
engagement team highlights high-value opportunities,
besides delivering insights into performance change
management progress. Biome approaches engagements
with the philosophy that analytics should augment the work
of cardiovascular teams, not replace physicians’ decision-
making autonomy. Biome provides the analytics that allows
physicians to understand the cost impacts of decisions and
the case studies and change management methodologies for
affecting performance improvement at client facilities.
Biome delivers performance bench-marking so that
cardiovascular teams can measure progress both internally
and against other cardiovascular centers.
Advice to Digital Health Entrepreneurs
Today, as healthcare decision-making becomes much more
nuanced and complex, Biome advises the budding
entrepreneurs in this field to stay focused and have an
unwavering vision. The company believes that healthcare
is a ‘team sport’ and each participant in the industry,
whether an entrepreneur, clinician, administrator, or patient,
rely on the others to achieve success. It also believes that
collaboration and communication are crucial to a successful
team and these capabilities bind the team with motivation
and positive approach.
Looking Forward
Biome’s distinctiveness is a breakthrough value-add for
cardiovascular teams providing noticeable clinical and
financial impact. Clients have appreciated the company’s
responsive services and analytic solutions. Talking about
the accolades received by the company so far, Stuart
asserts, “Our happy clients are our greatest award—when
we see the success that they achieve as a result of our
solution, we are motivated to develop even more models to
improve cardiovascular performance.”
Biome Analytics is focused on developing solution modules
in cardiovascular-related clinical areas such as stroke,
vascular, and neurology and is planning to roll these out to
all clients this year.

28. Conversa Health
Enhancing Communication, Building Relationships,
and Revamping the Care Experience
eaningful doctor-patient communication is
Mcentral to effective patient care management.
Not only does this enhance the patient
experience, it also helps encourage the patient to be a
more collaborative partner in their care. Today’s patients
expect transparent and timely flow of information, for
themselves as well as their loved ones. Developing a
personal and compassionate relationship with patients
has been a crucial role to play in the success of
healthcare providers. Conversa Health, an emerging
digital healthcare company, helps make the process of
building long-lasting relationships with the patients easy
through its innovative technology - The Conversa
Conversation Platform™.
Conversa is transforming healthcare from episodic
experiences to a continuous and personalized
relationship. By personalizing and automating care
communication, it envisions to make conversation a
cornerstone of the healthcare experience.
Proven Experience and Passion
West Shell III, CEO and Co-founder of Conversa, has
been a catalyst to the company’s fast-paced growth. A
5-time start-up CEO and the son of a real-estate
entrepreneur, Shell is a creative and enthusiastic leader.
He has a background in business strategy and an
impressive track record of building high growth,
innovative companies with world-class employees and
committed customers. His extensive experience marks
him unique in the crowd of digital health innovators, and
has helped him accelerate the company’s growth. With
his business acumen and expertise, Shell raised sufficient
funds from the right sources, partnered with the right
people, and is leading Conversa’s path of success.
Conversa is the brainchild of Shell and his partner
Dr. Philip Marshall, the Co-founder and Chief
Product Officer of the company. Although these two are
the creators of the company, Conversa owes its success
to a few prominent team members: Chris Edwards, the
Conversa enables
healthcare organizations to
monitor, manage and
communicate with their
patients more effectively at
scale than ever before
““
““
26 |July 2019|

29. West Shell III,
CEO & Co-founder
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30. Chief Client Experience & Marketing Officer,
Murray Brozinsky, the Chief Strategy Officer, Becky
James, Vice President of Operations, and Todd Grant,
Vice President of Finance and HR. This is a unique
group of dedicated healthcare professionals and
technologists who are passionate about transforming the
healthcare experience through automated, personalized
patient conversations.
Where it all started?
Conversa is influenced by Shell’s personal life
experience. He grew up with three sisters, all of whom
suffered from several chronic health conditions that
needed continuous monitoring. “My three sisters are the
ones who drove me to create Conversa. In each case, the
health system failed them. They did not receive the
educational materials and personalized information to
help them manage their conditions,” Shell said. “Once
they left the clinical encounter, they stopped being
patients.”
Unhappy with the conditions that his sisters faced, Shell
realized there was need for effective communication and
continuous monitoring of a patient’s health in order to
deliver better care. The will to improve the healthcare
communication process is the spark that drove him to
build Conversa Health.
Conversa Conversation Platform™
As healthcare’s conversation platform, Conversa delivers
an easy and meaningful way for care teams and patients
to communicate. It has an extensive library of over 700
clinically-intelligent conversation programs that include
asthma, chronic obstructive pulmonary disease (COPD),
congestive heart failure (CHF), diabetes, hypertension,
joint replacement, and many more. The company offers
innovative and scalable Conversational AI technology
enabling healthcare organizations to deliver automated,
personalized doctor-patient conversation experiences.
The improved scale and communication leads to more
meaningful patient relationships, effective population
management and, ultimately, better clinical and financial
outcomes.
The Clinically-intelligent technology
Conversa’s proprietary technology, which includes a
taxonomy-driven patient profile, automatically calibrates
the timing, channel of outreach, priority, and sequencing
of modules for the conversation content delivered. Over
time, Conversa’s smart technology learns and identifies
profile-based patterns that dynamically adjust and
improve what is asked, what is said, and what data is
collected from each patient in each conversation. This
feature allows the care providers to engage and monitor
the patients individually. No two conversation
experiences are alike because no two patients are alike.
Illustrious Acknowledgments
In its journey so far, Conversa has received many notable
awards and accolades for its valuable contribution to the
healthcare industry and best-in-class product. This
includes the honorable recognition as Digital Health
Disrupter and Leader in a research report published by
Juniper and the North American Patient Engagement
Solutions Technology Leadership Award by Frost and
Sullivan. The company was also chosen as an IDC
Patient Engagement Innovator, a Leading Care
Management Virtual Health Assistant by HealthXL, and
a Top Patient Relationship Management Solution by
Chilmark Research.
What’s Ahead?
More and more health organizations and healthcare
technology companies are using Conversa: Northwell
Health, Atrium Health System, University Hospitals,
Centura Health, Healthgrades, Allscripts, and many
more. As Conversa is well positioned to engage massive
populations on a personal level, the company is also
receiving tremendous interest from Pharma and Payer
organizations looking to engage patient users to drive
lower costs and improve health outcomes.
28 |July 2019|

32. MicrimaA Leading Organization Developing Technology
for Breast Cancer Screening
Today, over half a million women die of breast
cancer every year. Yet, if a tumor of less than 1cm
in size is detected, with no lymph involvement,
survival rates at 5 years are comparable with someone who
has not had cancer. Addressing this problem, an eminent
organization named Micrima was set up with the aim of
reducing the number of women who die of breast cancer by
developing a system that can aid earlier detection.
Micrima believes that the early detection of breast cancer
can be achieved by frequent screening from an early age,
which cannot be achieved with current screening methods.
Dedicated to improve the conventional diagnosis methods,
Micrima has set out to develop a system that is comfortable
for the patient, easy to interpret, and can be used frequently
from a much younger age in order to detect cancer early.
Originally based on technology for the detection of buried
landmines, the early application to breast imaging was
spun-out from the University of Bristol, as Micrima, in
2006. The founders of the company, Roy Johnson,
Professor Alan Preece, and Professor Ian Craddock,
recognized the impact the technology could potentially
have on breast cancer detection and mortality rates. Until
2014, Micrima continued to fund the work at the
University, when the reduced technology risk justified the
investment into establishing and growing the physical
company. Today, the company consists of 23 hardware,
software, and product development engineers with a small
commercial team. It is continuing to expand in all areas of
the business to meet the strategic aims of the company.
About the Intellectual Leader
Roy Johnson is the Executive Chairman of Micrima who
has over 35 years’ of enriching experience in the medical
device and diagnostics sector. He has been operating at
board level in both the UK and the USA. He is particularly
conversant with bringing complex technologies to market,
developing worldwide distribution networks, and
negotiating and managing strategic relationships with some
of the industry’s leading players. Following a career in large
USA corporates, he has founded 4 medical technology
companies and has advised the government in the Life
Sciences sector.
®
MARIA : A Unique Product of Micrima
MARIA® (Multistatic Array Radio-wave Image
Acquisition) is a revolutionary product of Micrima that uses
radio-waves to detect breast cancer. The procedure of
diagnosis includes the patient lying on their tummy on the
bed, such that breast to be imaged is pendulant through a
hole in the bed. Then, the array comes up to meet the breast,
there are different size inserts to accommodate different
sizes of breast. This array contains 60 antennae that each
transmits and receives. They each do this in turn, taking 22
seconds before the array rotates. The same process is
repeated twice more to build up a 3D map of the tissues
®
throughout the breast. MARIA measures the signal
reflected at the interface between tissues of different
electromagnetic material properties showing reflections
from the edges of lesions.
The commercial team at Micrima is working very closely
with its clinical partners ensuring the exact needs of the
®
customer are met. Today, MARIA is used as an adjunct to
Our major mission is to reduce
the number of women who die
of breast cancer by developing
a system that can aid earlier
detection of the tumor
““
““
30 |July 2019|

33. Roy Johnson
Executive Chairman
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34. other imaging modalities to reduce the chances of missing
the tumor. Producing the image takes about 1% of the
collected data on the breast tissues, so there is a lot more
information available. The next important step is to work
with the clinical partners in Europe to understand what
information they require and the best way to display such
information, adding higher levels of functionality to the
system. The company will launch the first step of this
program soon and will begin to classify regions of interest
as to the likelihood of these regions of interest being benign
or malignant.
Professor Lain Lyburn, a consultant radiologist at
Thirlestaine Breast Centre, Cheltenham, recently said,“We
®
have been involved in the evaluation of the MARIA system
for some time now and whilst it is currently offered as an
adjunct to other imaging modalities, particularly where
dense tissue is involved, the technique promises the exciting
ability to distinguish between tissue types in the future. Any
imaging modality that can readily give this sort of
functional information has the potential to influence many
points in the diagnostic and treatment pathways - there
could be less need for biopsies and possibly a reduction in
overtreatment.”
Challenges on the Way
The road to success is never easy. Likewise, Micrima, faced
many ups and downs in getting to this stage of
development. Right from persuading the investors to back
the growing enterprise to solving various technical
challenges along the way and ensuring the right approach to
the commercialization of the product, Micrima has
overcome all these hurdles.
On the financing front, though it wasn’t tough for the
company to convince the audiences of the unmet need
regarding breast cancer, the case still had to be made for its
specific technological approach. The crucial part was to
prove the capability and determination of the key personnel
and the growing management team. Today, Micrima is
supported by a growing list of quality investors who
passionately wish to take the organization forward.
Awards and Accreditations
In recent years, Micrima has been recognized with several
awards. Most of these awards are focused on the technology
®
and innovation of the MARIA system. These include
general innovation awards, like the ‘Medilink SW
innovation Award in 2018’. Micrima has also been honored
with ‘The Frost and Sullivan New Product Innovation
Award- Breast Imaging in 2019’ and the ‘Global Health and
Pharma Best Oncology Diagnostic Imaging Device
Manufacture in 2019 Award’.
Moving towards Success
The ongoing primary goal for Micrima is the evolution of
®
the MARIA software to deliver increasing degrees of
tissue differentiation. The company is hopeful to be able to
identify the type of malignancy along with the diagnosis of
the disease. “If we can assist radiologists by indicating
which are low grade, slow growing, and can/should be
monitored over time, and which are invasive, high grade,
and rapidly growing, this could have huge implications for
the treatment of breast cancer. There is also the possibility
to use this technology for detecting other types of cancer in
the body in the future,” says Roy.
On the commercial front, Micrima will continue its
progress in Europe. The company is also planning to take
this inventive technology to the US and Asia, once the
relevant regulatory approvals are in place.
32 |July 2019|

36. 34 |July 2019|
NEMAURA PHARMA
Offering Precise User-friendly Skin-based
Drug Delivery Technologies
emaura Pharma is a renowned organization that
Nstarted with developing a single technology for
delivering drugs through the skin. Today, it is a
company with over 100 patents filed, many of which are
already granted in multiple territories. The patents cover a
diverse array of platforms that allows the administration of
almost any drug through the skin.
Today, the company is at the forefront of Transdermal and
skin drug delivery having developed in-house specialist
knowledge and skills, and multiple proprietary novel
delivery systems. The company is well positioned to
provide solutions for complex drug delivery challenges,
using an array of formulation and device technologies.
Innovative Services
Nemaura started with a single technology for
chronotherapeutic drug delivery. Today, it has grown to
become a leading expert in the field of drug delivery
through the skin with multiple proprietary platform
technologies covering injectables, topical, and transdermal
formulations and over 21 drugs in the active development
using these platforms covering a wide range of therapeutic
areas.
Nemaura takes pride in being able to undertake complex
drug delivery challenges and developing both formulation
and device based solutions to tackle these challenges. The
company has in-house facilities to be able to design
develop, test and manufacture prototypes of devices and
drug formulations. It offers comprehensive pharmaceutical
formulation development services from concept to clinical
batch production and supply, all based on its proprietary
intellectual property.
About the Ingenious Leader
Dr. Faz Chowdhury, the dynamic Founder and CEO of
Nemaura Pharma originally trained as a drug formulator,
and also holds a Master’s degree in Microsystems and
Nanotechnology from Cranfield University in the UK, and a
PhD in nanomedicine and drug delivery from the University
of Oxford. So, far he has amassed over 100 patents across
over 20 technology platforms as sole inventor, as well as
having written textbook chapters for Wiley and Elsevier on
the subject of Bio-Nanosciences. Apart from Nemaura
Pharma, he also founded Nemaura Medical Inc., which is a
public listed company in the US (Nasdaq: NMRD), focused
on developing and commercializing non-invasive wearable
diagnostic systems.
Inspiring Journey
Prior to commencing studies at the University, Dr. Faz had
always planned to start his own technology company that
would give him something challenging to pursue. Initially,
the hard part for him was to decide when to set up a
company and in what field. During his undergraduate
studies, he discovered his strength in drug formulation and
delivery systems. Within his first eight years of employment
he decided that it was the right time in terms of experience
and exposure in the industry, to set up Nemaura Pharma.
We focus on innovation, not
just to create new drugs or
medications, but also to make
the existing healthcare
systems better.
““
““

37. Dr. Faz Chowdhury
Founder & CEO
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38. 36 |July 2019|
Today, as with most of the technology companies and more
so for companies working in the Pharmaceutical domain,
getting a first product to market could take over a decade.
There is a continuous cycle of bringing in new investment
which is no mean feat for any company as the criteria for
the investment is the same no matter how small or large the
company. Nemaura has seamlessly navigated this situation
with its compelling technology platforms and has raised
substantial funds both through product licensing as well as
from equity investors. Currently, the company is poised to
make some radical changes in the field of drug delivery in
particular and to the field of biologics and vaccines, which
collectively addresses a market opportunity in the 10's of
billions of dollars.
Colossal Achievement
When asked about the milestones the company has
achieved so far, Dr. Faz shared, “Early in the company’s
history we embarked on a development program for a
complex transdermal patch, and within 3 months we
completed initial proof of concept and subsequently went on
to successfully develop the product through to clinical trials
and submission to the FDA (United States Food and Drug
Administration).” This was a highly challenging
formulation with some serious intellectual property
constraints to navigate. There were few companies
including multinationals that were able to successfully
develop this product at the time. It was a mammoth
achievement for the company’s scientists and engineers,
reflecting on their ingenuity and expertise.
Awards and Accolades
Nemaura received the ‘Frost and Sullivan Technology
Leadership Award ’ in 2016 for Europe for its cutting-edge
innovative skin delivery technologies and for its potential
impact in the future for the administration of a wide range
of medicines. Last year, in 2018, the company also received
the ‘Medilink UK National Award ’ for drug delivery which
was further endorsement of its innovative technologies.
Words of Advice
“The healthcare space is and will always be a burgeoning
field with vast potential for innovation. Innovation in this
field does not necessarily have to be related to new
medicines and therapies, it can also be methods and devices
to make existing medicines easier to administer and
perhaps with enhanced safety profiles through drug
targeting or a change in the route of administration.
Companies should find a specific problem to solve and put
resources and effort into developing a practical and cost-
effective solution to that problem so that there is a clear
route to market, preferably built on clinical need, and if it
can then be applied to other drugs is then that is a bonus,
rather than starting with a platform technology at the
outset ” advises Dr. Faz to the budding entrepreneurs.
He further adds, “Finally, we can’t be phased by the long
lead times to develop and bring a technology or product to
market, which can in the case of a new drug delivery
technology over 10 years; if the technology has real
tangible benefits to the patient and the potential to reduce
the burden on healthcare providers then it is worth
pursuing.”
Future Prospect
One of the breakthrough technologies of Nemaura allows
proteins and vaccines to be produced as a solid dosage
form, in the form of a small particle or microneedle like
structure. The company has spent almost six years
perfecting this technology and securing intellectual property
around it. The company has a very ambitious goal of
adapting multiple vaccines in to this technology platform as
it offers two fundamental advantages: the first is that it
avoids the need for having to store the drug in a refrigerator
prior to use, and so reducing the cost of the cold chain
maintenance. The second advantage is that it is very easy to
use and can be self-administered without any training.
The company has estimated that this project would require
up to a decade to fully execute. Within the next 5 years,
Nemaura expects the bulk of over 21 drugs in development
to also be launched in to global markets, including drugs to
treat migraine, osteoporosis, and diabetes. Nemaura is
currently also planning to build its own state-of-the-art
research, development and manufacturing facility in
Loughborough, UK.

40. 38 |July 2019|
Transformative AI
Revolutionizing Healthcare with Deep Learning
n eminent start-up that creates artificial
Aintelligent algorithms to predict acute outcomes
of chronic diseases is Transformative AI. The
start-up’s vision is to develop a suite of AI-enabled
predictive analytics for a wide range of medical
conditions.
A Unique Approach
Today, globally, over six million people per year suffer
from Ventricular Tachyarrhythmia (VT), which is a
precursor to Sudden Cardiac Arrest (SCA). There is no
existing cardiac monitoring technology that can
automatically and accurately warn healthcare providers
of an oncoming arrest. Instead, bystanders or healthcare
providers rush to begin delivering cardiopulmonary
resuscitation (CPR) and if possible, prepare for
defibrillation. Transformative AI is aimed at changing
this scenario and with this goal, the start-up has its initial
focus on predicting Sudden Cardiac Arrest (SCA) before
it occurs.
Using advanced AI and statistical analysis techniques
from Cambridge University and CERN, Transformative
AI’s algorithm detects minute changes in patient
physiology and predicts an imminent real-time risk of
SCA. The unique algorithm would serve as the basis for
an early warning system that would improve patient-
survival for a broad spectrum of high-risk patients. This
approach maximizes the time for clinicians to provide
timely defibrillation, providing patients with the best
chance of survival and creating a step change in the
rapid-response workflow.
Furthermore, predictive monitoring holds the potential to
prevent ventricular tachyarrhythmia (VT) from
developing in a subset of patients. Thus, early warning
can usher in a new era of research into the use of
antiarrhythmic medicines to prevent SCA. The
company’s second wave of products will build upon its
initial work by improving care for related cardiac
conditions. Transformative AI believes that AI will
generate massive value when it is used to transform
healthcare workflows.
About the Trio
Dr. Marek Sirendi, one of the Co-founders, previously
worked as a data scientist on the Large Hadron Collider
at CERN, where he performed the world’s most precise
measurement of the W boson and designed real-time
decision algorithms for LHC collisions. He holds a PhD
We believe that with AI, we
can transform healthcare
workflows and save lives
while generating value for
patients, health systems,
and society
““
““

41. Dr. Marek Sirendi
Co-founder
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42. 40 |July 2019|
in Physics from the University of Cambridge and was a
Marie Curie fellow. He co-founded the company with
Dr. Joshua Oppenheimer, who is an Emergency
Medicine Physician, and Dr. Marek Rei, who is a
lecturer in the Department of Computer Science at the
University of Cambridge. Dr. Rei is a deep learning and
predictive analytics expert from his work at SwiftKey, a
company that created a predictive keyboard and exited to
Microsoft.
Exceptional Algorithm for the Betterment
Transformative AI’s artificially intelligent predictive
algorithm, CodeRhythm, predicts SCA within minutes,
with high accuracy on cardiac data. This would serve as
the basis for an early warning software-as-a-service that
would alert clinicians of impending ventricular
arrhythmias and improve patient survival across various
global healthcare settings.
Awards and Accolades
Transformative AI has won competitive public and
private award funding in the U.K., EU, and the U.S. It
has also won the Global Pistoia Alliance Audience
Choice Award.
The company was one of the first start-ups to work with
the Center for Medical Interoperability in the US. It was
also selected to work with Philips Healthworks and
Entrepreneur First and was named as ‘ TechCrunch’s Top
3 Entrepreneur First Start-ups’.
Turning Challenges into Opportunities
Asked about the major challenges they faced while
launching the start-up, they said, “As the predictive
healthcare field is so new with few precedents, we’ve had
to work with and will continue working with several
regulatory consultants and lawyers.”
As a healthcare start-up, Transformative AI has achieved
more than its share and will be looking forward to more
advancements and developments. Upon asking them
about what advice they would give to budding
entrepreneurs, Dr. Sirendi said, “Stick with your goal
and never give up.”