This document summarizes a study on pregnancy outcomes in women with autoimmune thyroiditis. The study examined 96 pregnant women with autoimmune thyroiditis who were divided into two groups. Complications of pregnancy occurred in 54.8% of women. Tests showed decreased levels of thyroid hormones and increased TSH levels in women with autoimmune thyroiditis compared to healthy pregnant women. The study concludes that autoimmune thyroiditis adversely affects pregnancy and increases the risk of miscarriage, and recommends routinely testing TSH levels early in pregnancy for women with autoimmune thyroiditis to prevent complications.
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At the same time, there was a decrease in free
thyroxine and an increase in the level of antibodies to
peroxidase (TPO) -18.9, which is apparently
associated with destructive changes in the thyroid
gland and a decrease in its function, which is an
indicator of its autoimmune damage. The ultrasound
picture in AIT was characterized by an enlargement
of the thyroid gland, a decrease in its echogenicity
and averaged 13.9 cm3.
Conclusion
1. In an iodine-deficient region, which is our region,
AIT is the most common endocrine pathology.
2. AIT has an adverse effect on the course of
pregnancy, there is a high risk of miscarriage and
abortion.
3. In pregnant women with AIT, there was a
decrease in the level of thyroid hormones and an
increase in the level of TSH in comparison with
similar indicators of healthy pregnant women.
4. For the prevention of complications of gestation
and premature pregnancy in women with AIT, it
is recommended to routinely determine TSH
blood from early gestation.
References:
[1] Аутоиммунный тиреоидит и беременность /
Варламова Т.М., Керова А.Н., Абуд И.Ю. и
др. // Акуш. и гин. 1999.
[2] Киселева, Т.П. Аутоиммунный тиреоидит и
йодная профилактика во время
беременности / Киселева Т.П., Сентюрина
Л.Б. // Проблемы эндокринологии. -2003.
[3] Кузнецова, И. А. Состояние щитовидной
железы у женщин с гиперпластическими
процессами органов репродуктивной
системы / Кузнецова И.А. // Вестник Санкт-
Петербургского университета. 2008.
[4] Репродуктивная функция женщин с
патологией щитовидиой железы /
Перминова С.Г., Фадеев В.В., КорнееваИ.Е.
и др. // Пробл. Репродукции.- 2006.
[5] Фадеев, В.В. Функциональное состояние
щитовидной железы у беременных женщин
— носительниц антител к тиреоидной
пероксидазе /•Г Т -С/
[6] Amelioration of some pregnancy-associated
variations in thyroid function by iodine
supplementation / Pedersen K. M., Laurberg P.,
Iversen E., Rnudsen P. R. et al. // J. Clin.
Endocrinol. Metab.
[7] Kennedy, R. L. The role of hCG in regulation
of the thyroid gland in normal and abnormal
pregnancy / Kennedy R. L., Darne J. // Obstet.
Gynecol.