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B.Srinivas Teja, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(2) 2014 [108-111]
www.ijrpp.com
~ 108~
ISSN Print: 2278 – 2648 IJRPP |Vol. 3 | Issue 2 | April - June - 2014
ISSN Online: 2278-2656 Journal Home page: www.ijrpp.com
Research article Open Access
Role of clinical pharmacist in prevalence of anemia
B.Srinivas Teja*1
, T.Tejaswi1
, SK.Shafiya 2
, Ramarao Nadendla3
.
1
Doctor of pharmacy, Chalapathi institute of pharmaceutical sciences, Guntur, India.
2
Assistant professor, Chalapathi institute of pharmaceutical sciences, Guntur, India.
3Principal, Chalapathi institute of pharmaceutical sciences, Guntur, India.
* Corresponding author: B.Srinivas Teja,
E-mail id: srinivasteja10@gmail.com
ABSTRACT
Anaemia is a major public health problem in developing countries like India and is especially seen among women of
childbearing age, during pregnancy and lactation. Nearly two-thirds of pregnant and one-half of non-pregnant
women in developing countries have anaemia, which increases the risk of maternal and foetal mortality and
morbidity.
Objective
To study the prevalence of anaemia among female population.
Materials and Methods
A total of 400 prescriptions were taken for a period of 3 months. Lab data from presription forms were taken in the
study to know Hb levels. The data was collected in a self administered data collection form.
Results
A high prevalence (64%) of anaemia (Hb<11g/dl) was observed. The prevalence of anaemia was significantly
higher in those aged ≥ 20 years. Significant association was found with woman’s age, parity, educational and socio-
economic status. However, family type and birth interval were not significantly associated with anaemia. Among the
320 prescriptions 82 were in the teenage (15-20) , 178were the middle aged (20-30) and 60 were the above middle
age (>30).
Conclusion
There is an urgent need to create awareness by the pharmacists by patient councelling among female population
about the complications associated with anaemia particularly in pregnancy and menstrual cycles.
Key words: Anaemia, Pregnancy, Haemoglobin. Pharmacists role.
INTRODUCTION
Anaemia is defined as decreased haemoglobin level,
or circulating red blood cells and it is the most
common problem during pregnancy. women with
haemoglobin level less than 11 g/dl should be
considered as anaemic. Iron deficiency can be due to
inadequate oral intake or poor bioavailability of iron
in foodstuffs. It can also occur due to excessive loss
of iron from the body. While the diet may contain
International Journal of Research in
Pharmacology & Pharmacotherapeutics
B.Srinivas Teja, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(2) 2014 [108-111]
www.ijrpp.com
~ 109~
adequate amounts of iron, poor bioavailability of
dietary iron is considered as the major reason for the
widespread prevalence of iron deficiency anaemia.
Malaria and hookworm infestations also contribute to
the anaemia. Moreover, mothers with fewer intervals
between the subsequent pregnancies become anaemic
as a result of additional demands and the loss of
blood during each delivery. Folate deficiency
anaemia has been seen in 25-50% of pregnant women
in India are seen and effects the people having low
economic status. According to World Health
Organization (WHO), in developing countries
anaemia affects nearly two thirds of pregnant and one
half of non- pregnant women. Prevalence of anaemia
in South Asian countries is among the highest in the
world. Among the South Asian countries, India has
the highest prevalence of anaemia (87%) and half of
the global maternal deaths due to anaemia occur in
South Asian countries; India contributes to about 80
per cent of the maternal deaths due to anaemia in
South Asia. In contrast, only 4-12% of women of
child-bearing age in developed countries suffer from
anaemia. Various studies from different regions of
the India have reported the prevalence of anaemia to
be between 33-100%. According to National Family
Health Survey-3 (NFHS-3), prevalence of anaemia
was 59% in pregnant women. A United Nations
expert panel considered severe anaemia (< 7g/dl) as
an associated cause in up to half of the maternal
deaths worldwide. In India, anaemia is the second
most common cause of maternal death, accounting
for 20% of total maternal deaths. Anaemia during
pregnancy can be associated with severe
complications like increased risks of maternal
mortality, premature delivery, low birth weight, etc.
Thus, routine screening tests for anaemia are
recommended in pregnant women. This survey
describes the factors such as maternal age, literacy,
socio-economic status, family type etc.
MATERIALS AND METHODS
A total of 400 prescription forms were taken for a
period of 3 months. Hb value less than 11gm/dL is
considered as anemia. Out of 400 forms only 320
were suitable for the study criteria. Data was
collected in a self administered data collection form
which contains all the details of the patient such as
age, marital status, family if it is nuclear or joint
family, dietary habits, socio –economic status.
General physical examination followed by systemic
examination was done in all patients by physician
during their regular ward rounds.The forms of
prescription are taken and then according to the
details in them the required data was collected.
Anaemia was classified according to WHO criteria.
Haemoglobin concentration of less than 11.0 gm/dl
was considered as anaemia. Haemoglobin
concentration of 10.0-10.9 gm/dl, 7.0-10.0 gm/dl and
less than 7.0gm/dl were considered to indicate mild,
moderate and severe anaemia respectively. The data
collected was compiled, tabulated and finally
analyzed.
RESULTS
None of the women enrolled was a vegetarian. More
than half of the study subjects were from joint
families and majority was illiterate followed by
primary level education. Most of studied subjects
belong to younger age group (15-30). The majority
of subjects observed from data forms had moderate
anemia 82 (25.6%) followed by severe anemia
178(55.6%) and mild anemia (18.5%) 60 . All the
women with multiple pregnancies were found to be
anemic. The severity of anemia found from the data
of prescribed forms was significantly higher in those
aged 20-30 years The peripheral blood smear (PBS)
identified normocytic, hypochromic and microcytic
types, morphological characteristics consistent with
iron deficiency anaemia.
Table :1.Age wise distribution
Age Number of prescription data forms Percentage
Age 15-20 82 25.6%
Age 20-30 178 55.6%
>30 60 18.5%
B.Srinivas Teja, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(2) 2014 [108-111]
www.ijrpp.com
~ 110~
Table: 2. Based on the socio economic status
Category of economic status Percentage
Low class 62.5%
Moderate class 35%
High class 2.5%
Table: 3. Based on the rate of literacy
Literacy rate
(n=320)
Yes No Percentage
Literates 45 275 14%
Illiterates 275 45 86%
DISSCUSSION
In this study it was found there was 64% of
prevalence of anemia. Majority of the women were
suffering from moderate anemia (52%) followed by
severe anemia (22%). The severity of anaemia was
significantly higher in women aged ≥ 35 years. Most
of the anaemic pregnant women were in the 25-29
year age group. We have found a much higher
prevalence of anaemia in our study. Very high
prevalence of anaemia (91 % ) early in pregnancy, an
indicator of the maternal anaemia, continues to be a
major health problem not only in this part of the
country but also in many other states of country and
worldwide that needs attention.
CONCLUSION
The prevalence of anemia was not significantly
related with birth interval and was seen to increase
with increase in parity. These factors could be taken
care of by timely health education to adolescent girls
regarding importance of literacy, delaying the age of
marriage, family spacing, small family norm, etc.
During pregnancy, efforts should be geared towards
the early detection and treatment of anemia before
delivery. The role of community pharmacist has a
major role in councelling and also, medical staff
managing pregnant women should endeavor to
investigate anemic pregnant women further in order
to bring the awareness of anemia , and avoiding its
increase by educating them. Screening for anemia,
treatment of anemic women, and availability of food
fortification (wheat flour with iron and folic acid),
milk sugar and salt with iron to build long term iron
stores remains the key to reduce anemia. Even
cooking in cast iron utensils improves iron content in
diet. The anemia control programme needs to be
implemented more efficiently
REFERENCES
[1] Gautam CS, Saha L, Sekhri K, Saha PK. Iron deficiency in pregnancy and the rationality of iron sup-
plements prescribed during pregnancy. Medscape J Med. 2008;10(12):283.
[2] Malee M. Anemia in Pregnancy. Obstet Gynecol. 2008; 112(1):201-7.
[3] Van den Broek NR. Let sky EA, white SA, Shenkin A. Iron status in pregnant women: which
measurements are valid? Br J Haematol. 1998 Dec;103(3):817-24.
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World Health Organization; 2001.
[5] Narasinga Rao BS, Vijayasarathy C, Prabhavathi T. Iron absorption from habitual diets of Indians studied
by the extrinsic tag technique. Indian J Med Res. 1983; 77 : 648-57.
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common salt (sodium chloride) fortified with iron to control anemia: results of a preliminary study. Br J
Nutr. 1980;43:45–51.
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www.ijrpp.com
~ 111~
[7] World Health Organization (WHO). The prevalence of Anaemia in women: a tabulation of available
information. Geneva, Switzerland: WHO; 1992.
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Med. 1980:11: 83-3
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Health Organization; 1976.
[17]Dass A, Bhatt I, Dhaliwal B. Megaloblastic anaemia in pregnancy (in Dehli). J Obstet Gynae Ind. 1967;
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deficiencies amongst pregnant women in a rural area of Haryana. Indian J Pediatr. 2004;71(11):1007-14.
[19]Thangaleela T, Vijayalakshmi P. Prevalence of anemia in pregnancy. Indian J Nutr Diet. 1994; 31: 26-29.
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Role of clinical pharmacist in prevalence of anemia

  • 1. B.Srinivas Teja, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(2) 2014 [108-111] www.ijrpp.com ~ 108~ ISSN Print: 2278 – 2648 IJRPP |Vol. 3 | Issue 2 | April - June - 2014 ISSN Online: 2278-2656 Journal Home page: www.ijrpp.com Research article Open Access Role of clinical pharmacist in prevalence of anemia B.Srinivas Teja*1 , T.Tejaswi1 , SK.Shafiya 2 , Ramarao Nadendla3 . 1 Doctor of pharmacy, Chalapathi institute of pharmaceutical sciences, Guntur, India. 2 Assistant professor, Chalapathi institute of pharmaceutical sciences, Guntur, India. 3Principal, Chalapathi institute of pharmaceutical sciences, Guntur, India. * Corresponding author: B.Srinivas Teja, E-mail id: srinivasteja10@gmail.com ABSTRACT Anaemia is a major public health problem in developing countries like India and is especially seen among women of childbearing age, during pregnancy and lactation. Nearly two-thirds of pregnant and one-half of non-pregnant women in developing countries have anaemia, which increases the risk of maternal and foetal mortality and morbidity. Objective To study the prevalence of anaemia among female population. Materials and Methods A total of 400 prescriptions were taken for a period of 3 months. Lab data from presription forms were taken in the study to know Hb levels. The data was collected in a self administered data collection form. Results A high prevalence (64%) of anaemia (Hb<11g/dl) was observed. The prevalence of anaemia was significantly higher in those aged ≥ 20 years. Significant association was found with woman’s age, parity, educational and socio- economic status. However, family type and birth interval were not significantly associated with anaemia. Among the 320 prescriptions 82 were in the teenage (15-20) , 178were the middle aged (20-30) and 60 were the above middle age (>30). Conclusion There is an urgent need to create awareness by the pharmacists by patient councelling among female population about the complications associated with anaemia particularly in pregnancy and menstrual cycles. Key words: Anaemia, Pregnancy, Haemoglobin. Pharmacists role. INTRODUCTION Anaemia is defined as decreased haemoglobin level, or circulating red blood cells and it is the most common problem during pregnancy. women with haemoglobin level less than 11 g/dl should be considered as anaemic. Iron deficiency can be due to inadequate oral intake or poor bioavailability of iron in foodstuffs. It can also occur due to excessive loss of iron from the body. While the diet may contain International Journal of Research in Pharmacology & Pharmacotherapeutics
  • 2. B.Srinivas Teja, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(2) 2014 [108-111] www.ijrpp.com ~ 109~ adequate amounts of iron, poor bioavailability of dietary iron is considered as the major reason for the widespread prevalence of iron deficiency anaemia. Malaria and hookworm infestations also contribute to the anaemia. Moreover, mothers with fewer intervals between the subsequent pregnancies become anaemic as a result of additional demands and the loss of blood during each delivery. Folate deficiency anaemia has been seen in 25-50% of pregnant women in India are seen and effects the people having low economic status. According to World Health Organization (WHO), in developing countries anaemia affects nearly two thirds of pregnant and one half of non- pregnant women. Prevalence of anaemia in South Asian countries is among the highest in the world. Among the South Asian countries, India has the highest prevalence of anaemia (87%) and half of the global maternal deaths due to anaemia occur in South Asian countries; India contributes to about 80 per cent of the maternal deaths due to anaemia in South Asia. In contrast, only 4-12% of women of child-bearing age in developed countries suffer from anaemia. Various studies from different regions of the India have reported the prevalence of anaemia to be between 33-100%. According to National Family Health Survey-3 (NFHS-3), prevalence of anaemia was 59% in pregnant women. A United Nations expert panel considered severe anaemia (< 7g/dl) as an associated cause in up to half of the maternal deaths worldwide. In India, anaemia is the second most common cause of maternal death, accounting for 20% of total maternal deaths. Anaemia during pregnancy can be associated with severe complications like increased risks of maternal mortality, premature delivery, low birth weight, etc. Thus, routine screening tests for anaemia are recommended in pregnant women. This survey describes the factors such as maternal age, literacy, socio-economic status, family type etc. MATERIALS AND METHODS A total of 400 prescription forms were taken for a period of 3 months. Hb value less than 11gm/dL is considered as anemia. Out of 400 forms only 320 were suitable for the study criteria. Data was collected in a self administered data collection form which contains all the details of the patient such as age, marital status, family if it is nuclear or joint family, dietary habits, socio –economic status. General physical examination followed by systemic examination was done in all patients by physician during their regular ward rounds.The forms of prescription are taken and then according to the details in them the required data was collected. Anaemia was classified according to WHO criteria. Haemoglobin concentration of less than 11.0 gm/dl was considered as anaemia. Haemoglobin concentration of 10.0-10.9 gm/dl, 7.0-10.0 gm/dl and less than 7.0gm/dl were considered to indicate mild, moderate and severe anaemia respectively. The data collected was compiled, tabulated and finally analyzed. RESULTS None of the women enrolled was a vegetarian. More than half of the study subjects were from joint families and majority was illiterate followed by primary level education. Most of studied subjects belong to younger age group (15-30). The majority of subjects observed from data forms had moderate anemia 82 (25.6%) followed by severe anemia 178(55.6%) and mild anemia (18.5%) 60 . All the women with multiple pregnancies were found to be anemic. The severity of anemia found from the data of prescribed forms was significantly higher in those aged 20-30 years The peripheral blood smear (PBS) identified normocytic, hypochromic and microcytic types, morphological characteristics consistent with iron deficiency anaemia. Table :1.Age wise distribution Age Number of prescription data forms Percentage Age 15-20 82 25.6% Age 20-30 178 55.6% >30 60 18.5%
  • 3. B.Srinivas Teja, et al / Int. J. of Res. in Pharmacology & Pharmacotherapeutics Vol-3(2) 2014 [108-111] www.ijrpp.com ~ 110~ Table: 2. Based on the socio economic status Category of economic status Percentage Low class 62.5% Moderate class 35% High class 2.5% Table: 3. Based on the rate of literacy Literacy rate (n=320) Yes No Percentage Literates 45 275 14% Illiterates 275 45 86% DISSCUSSION In this study it was found there was 64% of prevalence of anemia. Majority of the women were suffering from moderate anemia (52%) followed by severe anemia (22%). The severity of anaemia was significantly higher in women aged ≥ 35 years. Most of the anaemic pregnant women were in the 25-29 year age group. We have found a much higher prevalence of anaemia in our study. Very high prevalence of anaemia (91 % ) early in pregnancy, an indicator of the maternal anaemia, continues to be a major health problem not only in this part of the country but also in many other states of country and worldwide that needs attention. CONCLUSION The prevalence of anemia was not significantly related with birth interval and was seen to increase with increase in parity. These factors could be taken care of by timely health education to adolescent girls regarding importance of literacy, delaying the age of marriage, family spacing, small family norm, etc. During pregnancy, efforts should be geared towards the early detection and treatment of anemia before delivery. The role of community pharmacist has a major role in councelling and also, medical staff managing pregnant women should endeavor to investigate anemic pregnant women further in order to bring the awareness of anemia , and avoiding its increase by educating them. Screening for anemia, treatment of anemic women, and availability of food fortification (wheat flour with iron and folic acid), milk sugar and salt with iron to build long term iron stores remains the key to reduce anemia. Even cooking in cast iron utensils improves iron content in diet. The anemia control programme needs to be implemented more efficiently REFERENCES [1] Gautam CS, Saha L, Sekhri K, Saha PK. Iron deficiency in pregnancy and the rationality of iron sup- plements prescribed during pregnancy. Medscape J Med. 2008;10(12):283. [2] Malee M. Anemia in Pregnancy. Obstet Gynecol. 2008; 112(1):201-7. [3] Van den Broek NR. Let sky EA, white SA, Shenkin A. Iron status in pregnant women: which measurements are valid? Br J Haematol. 1998 Dec;103(3):817-24. [4] WHO/UNICEF/UNU. Iron Deficiency Anemia: Assessment, Prevention and Control. Geneva, Switzerland: World Health Organization; 2001. [5] Narasinga Rao BS, Vijayasarathy C, Prabhavathi T. Iron absorption from habitual diets of Indians studied by the extrinsic tag technique. Indian J Med Res. 1983; 77 : 648-57. [6] Nadiger HA, Krishnamachari KAVR, Nadamuni Naidu A, Narasinga Rao BS, Srikantia SG. The use of common salt (sodium chloride) fortified with iron to control anemia: results of a preliminary study. Br J Nutr. 1980;43:45–51.
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