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Dental diagnosticians have responsibility for
detecting disorders of the salivary glands
A familiarity with salivary gland disorders and
 applicable current imaging techniques is an
essential element of the clinician ’ s
armamentarium .
inflammatory disorders
Inflmmatory disorders are acute or chronic and may be secondary to
ductal obstruction by sialoliths, trauma, infection, or space-occupying
lesions such as neoplasia.
 Non – inflammatory disorders
are metabolic and secretory abnormalities associated with diseases of
nearly all the endocrine glands, malnutrition, and neurologic disorders
.
space-occupying masses.
are cystic or neoplastic; the neoplasms are benign or
malignant.
Clinical Signs and
Symptoms
Disease of major salivary glands may have single
or multiple feature :-
A. Swelling in the area of parotid and
submandibular gland
B. Pain and altered salivary flow
C. The periodicity and longevity of these symptoms
D. a review of the medical history and physical
condition of the patient may provide important
information.
BILATERALUNILATERAL
 Bacterial sialadenitis
 Viral sialadenitis (mumps)
 Sjögren syndrome
Alcoholic hypertrophy
 Medication-induced
hypertrophy (iodine, heavy
metals)
 Human immunodefi ciency
virus – associated multicentric
cysts
 Masseter muscle
hypertrophy
 Accessory salivary glands
Bacterial sialadenitis
 Sialodochitis
 Cyst
 Benign neoplasm
 Malignant neoplasm
 Intraglandular lymph
node
 Masseter muscle
hypertrophy
 Lesions of adjacent
osseous structures
BILATERALUILATERAL
Bacterial
sialadenitis
 Sjögren syndrome
 Lymphadenitis
 Branchial cleft cyst
 Submandibular
space infection
Bacterial
sialadenitis
 Sialodochitis
 Fibrosis
 Cyst
 Benign neoplasm
 Malignant
neoplasm
Diagnostic imaging of salivary gland disease may
be undertaken to differentiate inflammatory
processes from neoplastic disease .
diffuse disease from focal suppurative disease,
identify and localize sialoliths, and demonstrate
ductal morphology anddetermine the anatomic
location of a tumor, in addition , differentiate
benign from malignant tumor .
Plain film radiography is a fundamental part of
the examination of the salivary glands and may
provide sufficient information to preclude
the use of more sophisticated and expensive
imaging techniques .
It has the potential to identify unrelated pathoses
in the areas of the salivary glands that may be
mistakenly identified as salivary gland disease,
such as resorptive or osteoblastic changes in
adjacent bone .
PLAIN FILM
RADIOGRAPHY Panoramic and conventional posteroanterior (PA) skull radiographs
may demonstrate bony lesions, thus eliminating salivary pathosis
from the differential diagnosis.
 Unilateral or bilateral functional or congenital hypertrophy of the
masseter muscle may clinically mimic a salivary tumor. A plain film
extraoral radiograph may demonstrate a deep antegonial notch,
overdeveloped mandibular angle, and exostosis on the outer
surface of the angle in cases of masseter hypertrophy.
 Plain film radiographs are useful when the clinical impression,
 supported by a compatible history, suggests the presence of
sialoliths
 (stones or calculi).
 Sialoliths in the anterior two thirds of the submandibular duct are
typically imaged with a cross-sectional mandibular occlusal
projection
 The posterior part of the duct is demonstrated with an over-the-
shoulder occlusal projection view, where the directing cone is
placed on the shoulder and central
 ray directed in an anterior direction through the angle of the
mandible, with the patient ’ s head tilted to the unaffected side and
rotated back .
 Parotid sialoliths are more difficult to demonstrate than the
submandibular variety as a result of the tortuous course of Stensen
duct around the anterior border of the masseter and through the
buccinator muscle. As a rule, only sialoliths anterior to the masseter
muscle
 can be imaged on an intraoral film.
Underexposed mandibular occlusal
radiograph demonstrating radiopaque
sialolith in
Wharton duct. Note the classic
laminated appearance.
.
Periapical radiographs of the same case. The
radiopaque calculus can be localized lingual to the
teeth by applying appropriate object localization
rules
An axial bone algorithm CT image
showing a sialolith in the
submandibular duct (arrow).
A panoramic projection frequently demonstrates
sialoliths in the posterior duct or reveals
intraglandular sialoliths in the submandibular
gland.
The image of most parotid sialoliths is
superimposed over the ramus and body of the
mandible .
To demonstrate sialoliths in the submandibular
gland, the lateral projection is modified by
opening the mouth, extending the chin, and
depressing the tongue with the index finger.
Sialoliths in the distal portion of Stensen duct
or in the parotid gland are difficult to
demonstrate by intraoral or lateral extraoral
views. However, a PA skull projection with the
cheeks puffed out may move the image of the
sialolith free of the bone .
Anteroposterior skull view with cheek blown
out to provide air contrast to reveal a parotid
sialolith (arrow).
 First performed in 1902, sialography is a radiographic technique where a
radiopaque contrast agent is infused into the ductal system of a salivary
gland before imaging with plain films, fluoroscopy, panoramic radiography,
conventional tomography, or CT. Sialography remains the most detailed
way to image the ductal system .
 The parotid and submandibular glands are more readily studied with
 this technique.
 A survey or “ scout” film is usually made before the infusion of the
contrast solution into the ductal system
.
With this technique, Lipid-soluble (e.g., Ethiodol) or non –Lipid-soluble (e.g.,
Sinografi n) contrast solution is then slowly infused
until the patient feels discomfort (usually between 0.2 and 1.5 ml).
 These iodine-containing agents render the ductal system
radiopaque, The image of the ductal system appears as “ tree limbs,
” with no area of the gland devoid of ducts. With acinar filling, the “
tree ” comes into “ bloom, ” which is the typical appearance of the
parenchymal opacification phase .
 Non – lipid-soluble contrast agents are preferred because of reports
of inflammatory reactions subsequent to inadvertent extravasation
of lipid-soluble agents .
 Sialography is indicated for the evaluation of chronic inflammatory
diseases and ductal pathoses. Contraindications include acute
infection, known sensitivity to iodine-containing compounds, and
immediately anticipated thyroid function tests.
A, Lateral projection of the parotid
demonstrating opacification all the way to the
terminal ducts and acini.
B, Anteroposterior projection of the same
gland demonstrating
“ parenchymal blushing ” from acinar opacifi
cation.
Sialogram of Normal Submandibular Gland. This lateral
view demonstrates parenchymal blushing. Normal fine branching
is
visible. Lack of parenchymal blushing at the anteroinferior
margin is
caused by radiographic burnout.
CT is useful in evaluating structures in and
adjacent to salivary glands; it displays both
soft and hard tissues and minute differences
in soft tissue densities .
CT is useful in assessing acute inflammatory
processes and abscesses as well as cysts,
mucoceles, and neoplasia. Calcifications such
as sialoliths are also well depicted with CT.
•CT Images with Soft Tissue Algorithm. A, Axial view
demonstrating bilateral enlargement of the parotid
glands (arrowheads).
B, Coronal view of the same patient. The
clinical/histopathologic
diagnosis was
•autoimmune parotitis.
MRI for soft tissue mass details and localization
Differanciates :
St vs. Ht
Normal vs. abnormal tissue
Identifies facial nerve ( parotid )
Containdications:
-pacemaker
-cochlear implant
These magnetic resonance images reveal a lymphoepithelial cyst involving the
right
parotid gland. This axial T1-weighted image reveals a well-defined circular
lesion involving the right
parotid gland with an internal signal isointense to muscle
, and the matching T2-weighted image
reveals that the lesion has a high
internal signal because of the fluid
content
SCINTIGRAPHY (NUCLEAR MEDICINE,
POSITRON
EMISSION COMPUTED TOMOGRAPHY)
Selective up take of techntium
Assesees silvary gland function (not anatomy)
Expel technetium after stimulations
Scintigraphy. A, 99m Tc-pertechnetate
scan of the salivary glands (right and left anterior
oblique views) demonstrates increased uptake of
radioisotope in the right parotid gland (black
arrowhead). B, Scintigram taken after
administration
of a sialogog (lemon juice) demonstrates
retention of isotope in right parotid gland (white
arrowheads). This is a typical presentation of
salivary
stasis, Warthin tumor, or oncocytoma.
ULTRASONOGRAPHY
For superficial , soft tissue swilling
Differentioates cystic vs. solid
Us-guide FNA
ULTRASONOGRAPHY
Ultrasonography (US) Image of Right Parotid
Gland. A
well-delineated solid mass is suggested by
echo returns within the
lesion (arrows). US appearance is typical of a
benign salivary tumor
ULTRASONOGRAPHY
SALIVARY GLAND RADIOLOGY

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SALIVARY GLAND RADIOLOGY

  • 1.
  • 2.
  • 3. Dental diagnosticians have responsibility for detecting disorders of the salivary glands A familiarity with salivary gland disorders and  applicable current imaging techniques is an essential element of the clinician ’ s armamentarium .
  • 4. inflammatory disorders Inflmmatory disorders are acute or chronic and may be secondary to ductal obstruction by sialoliths, trauma, infection, or space-occupying lesions such as neoplasia.  Non – inflammatory disorders are metabolic and secretory abnormalities associated with diseases of nearly all the endocrine glands, malnutrition, and neurologic disorders . space-occupying masses. are cystic or neoplastic; the neoplasms are benign or malignant.
  • 5. Clinical Signs and Symptoms Disease of major salivary glands may have single or multiple feature :- A. Swelling in the area of parotid and submandibular gland B. Pain and altered salivary flow C. The periodicity and longevity of these symptoms D. a review of the medical history and physical condition of the patient may provide important information.
  • 6.
  • 7. BILATERALUNILATERAL  Bacterial sialadenitis  Viral sialadenitis (mumps)  Sjögren syndrome Alcoholic hypertrophy  Medication-induced hypertrophy (iodine, heavy metals)  Human immunodefi ciency virus – associated multicentric cysts  Masseter muscle hypertrophy  Accessory salivary glands Bacterial sialadenitis  Sialodochitis  Cyst  Benign neoplasm  Malignant neoplasm  Intraglandular lymph node  Masseter muscle hypertrophy  Lesions of adjacent osseous structures
  • 8. BILATERALUILATERAL Bacterial sialadenitis  Sjögren syndrome  Lymphadenitis  Branchial cleft cyst  Submandibular space infection Bacterial sialadenitis  Sialodochitis  Fibrosis  Cyst  Benign neoplasm  Malignant neoplasm
  • 9. Diagnostic imaging of salivary gland disease may be undertaken to differentiate inflammatory processes from neoplastic disease . diffuse disease from focal suppurative disease, identify and localize sialoliths, and demonstrate ductal morphology anddetermine the anatomic location of a tumor, in addition , differentiate benign from malignant tumor .
  • 10. Plain film radiography is a fundamental part of the examination of the salivary glands and may provide sufficient information to preclude the use of more sophisticated and expensive imaging techniques . It has the potential to identify unrelated pathoses in the areas of the salivary glands that may be mistakenly identified as salivary gland disease, such as resorptive or osteoblastic changes in adjacent bone .
  • 11. PLAIN FILM RADIOGRAPHY Panoramic and conventional posteroanterior (PA) skull radiographs may demonstrate bony lesions, thus eliminating salivary pathosis from the differential diagnosis.  Unilateral or bilateral functional or congenital hypertrophy of the masseter muscle may clinically mimic a salivary tumor. A plain film extraoral radiograph may demonstrate a deep antegonial notch, overdeveloped mandibular angle, and exostosis on the outer surface of the angle in cases of masseter hypertrophy.  Plain film radiographs are useful when the clinical impression,  supported by a compatible history, suggests the presence of sialoliths  (stones or calculi).
  • 12.  Sialoliths in the anterior two thirds of the submandibular duct are typically imaged with a cross-sectional mandibular occlusal projection  The posterior part of the duct is demonstrated with an over-the- shoulder occlusal projection view, where the directing cone is placed on the shoulder and central  ray directed in an anterior direction through the angle of the mandible, with the patient ’ s head tilted to the unaffected side and rotated back .  Parotid sialoliths are more difficult to demonstrate than the submandibular variety as a result of the tortuous course of Stensen duct around the anterior border of the masseter and through the buccinator muscle. As a rule, only sialoliths anterior to the masseter muscle  can be imaged on an intraoral film.
  • 13. Underexposed mandibular occlusal radiograph demonstrating radiopaque sialolith in Wharton duct. Note the classic laminated appearance. .
  • 14. Periapical radiographs of the same case. The radiopaque calculus can be localized lingual to the teeth by applying appropriate object localization rules
  • 15. An axial bone algorithm CT image showing a sialolith in the submandibular duct (arrow).
  • 16. A panoramic projection frequently demonstrates sialoliths in the posterior duct or reveals intraglandular sialoliths in the submandibular gland. The image of most parotid sialoliths is superimposed over the ramus and body of the mandible . To demonstrate sialoliths in the submandibular gland, the lateral projection is modified by opening the mouth, extending the chin, and depressing the tongue with the index finger.
  • 17. Sialoliths in the distal portion of Stensen duct or in the parotid gland are difficult to demonstrate by intraoral or lateral extraoral views. However, a PA skull projection with the cheeks puffed out may move the image of the sialolith free of the bone .
  • 18.
  • 19.
  • 20. Anteroposterior skull view with cheek blown out to provide air contrast to reveal a parotid sialolith (arrow).
  • 21.  First performed in 1902, sialography is a radiographic technique where a radiopaque contrast agent is infused into the ductal system of a salivary gland before imaging with plain films, fluoroscopy, panoramic radiography, conventional tomography, or CT. Sialography remains the most detailed way to image the ductal system .  The parotid and submandibular glands are more readily studied with  this technique.  A survey or “ scout” film is usually made before the infusion of the contrast solution into the ductal system . With this technique, Lipid-soluble (e.g., Ethiodol) or non –Lipid-soluble (e.g., Sinografi n) contrast solution is then slowly infused until the patient feels discomfort (usually between 0.2 and 1.5 ml).
  • 22.  These iodine-containing agents render the ductal system radiopaque, The image of the ductal system appears as “ tree limbs, ” with no area of the gland devoid of ducts. With acinar filling, the “ tree ” comes into “ bloom, ” which is the typical appearance of the parenchymal opacification phase .  Non – lipid-soluble contrast agents are preferred because of reports of inflammatory reactions subsequent to inadvertent extravasation of lipid-soluble agents .  Sialography is indicated for the evaluation of chronic inflammatory diseases and ductal pathoses. Contraindications include acute infection, known sensitivity to iodine-containing compounds, and immediately anticipated thyroid function tests.
  • 23. A, Lateral projection of the parotid demonstrating opacification all the way to the terminal ducts and acini. B, Anteroposterior projection of the same gland demonstrating “ parenchymal blushing ” from acinar opacifi cation.
  • 24.
  • 25. Sialogram of Normal Submandibular Gland. This lateral view demonstrates parenchymal blushing. Normal fine branching is visible. Lack of parenchymal blushing at the anteroinferior margin is caused by radiographic burnout.
  • 26. CT is useful in evaluating structures in and adjacent to salivary glands; it displays both soft and hard tissues and minute differences in soft tissue densities . CT is useful in assessing acute inflammatory processes and abscesses as well as cysts, mucoceles, and neoplasia. Calcifications such as sialoliths are also well depicted with CT.
  • 27. •CT Images with Soft Tissue Algorithm. A, Axial view demonstrating bilateral enlargement of the parotid glands (arrowheads). B, Coronal view of the same patient. The clinical/histopathologic diagnosis was •autoimmune parotitis.
  • 28. MRI for soft tissue mass details and localization Differanciates : St vs. Ht Normal vs. abnormal tissue Identifies facial nerve ( parotid ) Containdications: -pacemaker -cochlear implant
  • 29. These magnetic resonance images reveal a lymphoepithelial cyst involving the right parotid gland. This axial T1-weighted image reveals a well-defined circular lesion involving the right parotid gland with an internal signal isointense to muscle , and the matching T2-weighted image
  • 30. reveals that the lesion has a high internal signal because of the fluid content
  • 31. SCINTIGRAPHY (NUCLEAR MEDICINE, POSITRON EMISSION COMPUTED TOMOGRAPHY) Selective up take of techntium Assesees silvary gland function (not anatomy) Expel technetium after stimulations
  • 32. Scintigraphy. A, 99m Tc-pertechnetate scan of the salivary glands (right and left anterior oblique views) demonstrates increased uptake of radioisotope in the right parotid gland (black arrowhead). B, Scintigram taken after administration of a sialogog (lemon juice) demonstrates retention of isotope in right parotid gland (white arrowheads). This is a typical presentation of salivary stasis, Warthin tumor, or oncocytoma.
  • 33.
  • 34. ULTRASONOGRAPHY For superficial , soft tissue swilling Differentioates cystic vs. solid Us-guide FNA
  • 35. ULTRASONOGRAPHY Ultrasonography (US) Image of Right Parotid Gland. A well-delineated solid mass is suggested by echo returns within the lesion (arrows). US appearance is typical of a benign salivary tumor