Observación De Hongos

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Observación de hongos Laboratorio de Microbiología

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Normal flora is the term used to describe the various bacteria and fungi that are permanent residents of certain body sites, especially the skin, oropharynx, colon, and vagina (Tables 6–1 and 6–2). Viruses and parasites (protozoa and helminths), which are the other major groups of microorganisms, are usually not considered members of the normal flora, although they can be present in asymptomatic individuals. The normal flora organisms are often referred to as commensals. Commensals are organisms that derive benefit from another host but do not damage that host. The term human microbiome is often used to describe the normal flora. The members of the normal flora play a role both in the maintenance of health and in the causation of disease in three significant ways: (1) They can cause disease, especially in immunocompromised and debilitated individuals. Although these organisms are nonpathogens in their usual anatomic location, they can be pathogens in other parts of the body. (2) They constitute a protective host defense mechanism. The nonpathogenic resident bacteria occupy attachment sites on the skin and mucosa that can interfere with colonization by pathogenic bacteria. The ability of members of the normal flora to limit the growth of pathogens is called colonization resistance. If the normal flora is suppressed, pathogens may grow and cause disease. For example, antibiotics can reduce the normal colonic flora that allows Clostridium difficile, which is resistant to the antibiotics, to overgrow and cause pseudomembranous colitis. (3) They may serve a nutritional function. The intestinal bacteria produce several B vitamins and vitamin K. Poorly nourished people who are treated with oral antibiotics can have vitamin deficiencies as a result of the reduction in the normal flora. However, since germ-free animals are well-nourished, the normal flora is not essential for proper nutrition. THE HUMAN MICROBIOME The human microbiome is the term used to describe the thousands of microbes (“microbiota”) located on the skin, on mucosal surfaces, and within the lumen of the TABLE 6–2 Medically Important Members of the Normal Flora Location Important Organisms1 Less Important Organisms2 Skin Staphylococcus epidermidis Staphylococcus aureus, Corynebacterium (diphtheroids), various streptococci, Pseudomonas aeruginosa, anaerobes (e.g., Propionibacterium), yeasts (e.g., Candida albicans) Nose S. aureus3 S. epidermidis, Corynebacterium (diphtheroids), various streptococci Mouth Viridans streptococci Various streptococci, Eikenella corrodens Dental plaque Streptococcus mutans Prevotella intermedia, Porphyromonas gingivalis Gingival crevices Various anaerobes (e.g., Bacteroides, Fusobacterium, streptococci, Actinomyces) Throat Viridans streptococci Various streptococci (including Streptococcus pyogenes and Streptococcus pneumoniae), Neisseria species, Haemophilus influenzae, S. epidermidis Colon Bacteroides fragilis, Escherichia

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