mer EcoRO three-legged stool for retirement savi What sources of income make up the three-
legg ings?
Solution
Sources of income that make up the three legged stool for retirement savings: Social security,
Retirement plans and Personal savings.
Stool leg 1 : SOCIAL SECURITY:
Social security was designed to provide a minimum level of support . That is why it is also
known as social insurance. For every dollar a person earn , the government takes a percentage to
support social security . Your employer is also required to pay the same amount. When a person
retire , having a history of higher esrnings means social security will replace less of pre-
retirement income.
Stool leg 2 : RETIREMENT PLANS:
Retirement plans come in two forms: defined benefit and defined contribution. Defined benefit
pays you a retirement income and is usually paid in full by your employer. Defined contribution
plan provides an annual contribution to an account in your name, based on your annual salary.
Stool leg 3: PERSONAL SAVINGS:
Retirement income will depend on person\'s savings..
Name a protein that contacts the insulin receptor inside the cell.pdf
1. Name a protein that contacts the insulin receptor inside the cell after it has been activitated by
insulin. (One adaptor molecule)
Name a protein that contacts the insulin receptor inside the cell after it has been activitated by
insulin. (One adaptor molecule)
Solution
Insulin mediated targets are lipid metabolism, glucose and protein metabolism and cell growth
and differentiation. To activate and control all these targets, various signalling pathways are
mediated by adaptor molecules. And such adaptor molecules are IRS (Insulin Receptor
Substrates), the SHC (Src and Collagen Homologues) and the GRB2 (Growth Factor Receptor
Binding protein-2)
IRS (Insulin receptor substrate) is one such adaptor protein that binds to intracellular domain of
insulin receptor and activates two pathways. One is phosphatidylinositol 3-kinase (PI3K)
pathway and other is MAPK (mitogen activated protein kinase, also known as ERK or
extracellular signal regulated kinase) pathway.
PI3K pathway is responsible for metabolic effects of insulin while MAPK is responsible for
regulation of gene expression.
