This document discusses synthetic biology and biobricks. It explains that synthetic biology aims to engineer organisms using standardized biological parts or biobricks which encode specific functions. These biobricks allow modifying cell behavior without fully understanding the system. The document also discusses both the potential benefits of synthetic biology such as producing fuels and medicines as well as the risks if organisms escaped or were misused.

2. Universidad Autónoma de Nuevo León
Facultad de Ciencias Biológicas
Licenciado en Biotecnología Genómica
Primer semestre Grupo 413
Bioética – Dr. Carlos Jair Guerrero-García
• Martín Bernal López 1543619
• Eloisa Garza González 1636948
• Jennifer Ainara Godínez Pérez 1717821
• Celeste F. Gracia Rodríguez 1717817
• Erick Irving Hernández Villarreal 1634301

3. Agenda
• Abstract
• Bioingeniería
• Biología sintética
• Biobricks
• Riesgos y beneficios

4. El ensayo fue escrito por Zachary
Russ estudiante de primer año
cursando la Carrera de Bioingeniería
en la Universidad de Maryland.

5. Un bioingeniero es quién se ocupa de todos los
aspectos tecnológicos relacionados de alguna
manera en la medicina y la biología. Además, al
igual que un biólogo o un médico, se encarga del
estudio y el análisis de todos los organismos vivos.

6. - Nobel Laureate and physicist Richard P. Feynman
La bioingeniería aún y con todos sus logros tiene que
crear vida para encajar en el mismo tipo de precisas
especificaciones que los ingenieros químicos tienen que
hacer con moléculas y que los ingenieros mecánicos
tienen con lasmáquinas.

7. “The newly introduced field of synthetic biology
(synbio) represents a response to that problem.”
¿QUÉ ES?

8. La base de la Biología Sintética son los biobricks, fragmentos
de ADN que codifican para una característica biológica y que
pueden ser combinados para formar circuitos complejos.
Los biobricks constituyen, por tanto, la unidad estándar y
modular básica que realiza una función simple y permiten
modificar el comportamiento de una célula sin la
necesidad de conocer a priori el funcionamiento exacto
del sistema. http://syntheticbiology.org/BioBricks.html

9. The BioBricks project takes the former approach, and, by
designing organisms using standardized building blocks, makes
genetic engineering easier and much more efficient. BioBricks
provide the potential to make biochemicals and pharmaceuticals
quickly and easily without having to worry about unforeseen
interactions between the drug genes and vestigial genes

10. With complete control over the genomes of their organisms, synbioengineers
can introduce specific weaknesses into their organisms, such as a
dependency on a particular amino acid, so that lab experiments have little
chance of surviving in the wild. Without the noise data that natural
organisms have in their genomes, synthetic organisms will also be very
limited in genetic variation and virtually unable to adapt to new conditions.

11. While accidental harm is significant, in the
age of terrorism in which we live, malice is
also an important factor in technologies.
There is even more risk to not using synthetic
biology. Synthetic biology can produce organisms
to clean up pollution and provide clean energy.
Proteins and food can be created without wasting
energy on a full-sized organism, providing cheap
ways to make nutritious meals for millions.
Synbio is the opportunity to gain power over life
and achieve the ultimate goal in engineering – to
be so familiar with a part that its behavior can be
modeled, predicted, and used; and the uses are
limitless

12. “The genetic code is 3.6 billion years old. It's time for a rewrite.”

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7. http://microbioun.blogspot.mx/2014/03/biologia-sintetica-para-que-construir.html
8. http://www.elmundo.es/ciencia/2014/05/07/536a6edae2704e7f278b4584.html