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Resuscita)ve	
  Thoracotomy	
  
Michael	
  Meyer,	
  M.D.,	
  FACS	
  
COL,	
  MC	
  
Madigan	
  Army	
  Medical	
  Center	
  
Introduc)on	
  
•  History	
  
•  Studies	
  
•  Review	
  of	
  CPG	
  
Requisite	
  Quotes	
  
1883	
  Theodore	
  Bilroth	
  
“The	
  surgeon	
  who	
  
should	
  aMempt	
  to	
  suture	
  
a	
  wound	
  of	
  the	
  heart	
  
would	
  lose	
  the	
  respect	
  of	
  
his	
  collegues.”	
  
	
  
Requisite	
  Quotes	
  
	
  
1896	
  James	
  Paget	
  
“Surgery	
  of	
  the	
  heart	
  has	
  
probably	
  reached	
  the	
  
limits	
  set	
  by	
  nature	
  to	
  all	
  
surgery:	
  no	
  new	
  method	
  
and	
  no	
  new	
  discovery	
  can	
  
overcome	
  the	
  natural	
  
difficul)es	
  that	
  aMend	
  a	
  
wound	
  of	
  the	
  heart.”	
  
History	
  
•  1649	
  Riolanus:	
  First	
  described	
  
pericardiocentesis	
  
•  1829	
  Larrey:	
  First	
  successful	
  
pericardiocentesis	
  for	
  trauma	
  
•  1896	
  Rehn:	
  First	
  successful	
  human	
  cardiac	
  
repair	
  aXer	
  a	
  knife	
  wound	
  to	
  the	
  RV	
  
•  1901	
  Igelsrund:	
  First	
  open	
  cardiac	
  massage	
  for	
  
cardiac	
  arrest	
  
•  1902	
  Hill:	
  First	
  cardiorrhaphy	
  in	
  the	
  US	
  
	
  
History	
  
•  1649	
  Riolanus:	
  First	
  described	
  
pericardiocentesis	
  
•  1829	
  Larrey:	
  First	
  successful	
  
pericardiocentesis	
  for	
  trauma	
  
•  1896	
  Rehn:	
  First	
  successful	
  human	
  cardiac	
  
repair	
  aXer	
  a	
  knife	
  wound	
  to	
  the	
  RV	
  
•  1901	
  Igelsrund:	
  First	
  open	
  cardiac	
  massage	
  for	
  
cardiac	
  arrest	
  
•  1902	
  Hill:	
  First	
  cardiorrhaphy	
  in	
  the	
  US	
  
	
  
History	
  
•  1649	
  Riolanus:	
  First	
  described	
  
pericardiocentesis	
  
•  1829	
  Larrey:	
  First	
  successful	
  
pericardiocentesis	
  for	
  trauma	
  
•  1896	
  Rehn:	
  First	
  successful	
  human	
  cardiac	
  
repair	
  aXer	
  a	
  knife	
  wound	
  to	
  the	
  RV	
  
•  1901	
  Igelsrund:	
  First	
  open	
  cardiac	
  massage	
  for	
  
cardiac	
  arrest	
  
•  1902	
  Hill:	
  First	
  cardiorrhaphy	
  in	
  the	
  US	
  
	
  
History	
  
•  1649	
  Riolanus:	
  First	
  described	
  
pericardiocentesis	
  
•  1829	
  Larrey:	
  First	
  successful	
  
pericardiocentesis	
  for	
  trauma	
  
•  1896	
  Rehn:	
  First	
  successful	
  human	
  cardiac	
  
repair	
  aXer	
  a	
  knife	
  wound	
  to	
  the	
  RV	
  
•  1901	
  Igelsrund:	
  First	
  open	
  cardiac	
  massage	
  for	
  
cardiac	
  arrest	
  
•  1902	
  Hill:	
  First	
  cardiorrhaphy	
  in	
  the	
  US	
  
	
  
Tromsø	
  Amtsykehus	
  
History	
  
•  1649	
  Riolanus:	
  First	
  described	
  
pericardiocentesis	
  
•  1829	
  Larrey:	
  First	
  successful	
  
pericardiocentesis	
  for	
  trauma	
  
•  1896	
  Rehn:	
  First	
  successful	
  human	
  cardiac	
  
repair	
  aXer	
  a	
  knife	
  wound	
  to	
  the	
  RV	
  
•  1901	
  Igelsrund:	
  First	
  open	
  cardiac	
  massage	
  for	
  
cardiac	
  arrest	
  
•  1902	
  Hill:	
  First	
  cardiorrhaphy	
  in	
  the	
  US	
  
	
  
History	
  
•  1927	
  Djanelidze:	
  published	
  detailed	
  review	
  of	
  
535	
  cases	
  of	
  cardiac	
  injuries	
  
•  1939	
  Bigger:	
  pericardiocentesis	
  should	
  be	
  
used	
  both	
  diagnos)cally	
  and	
  therapeu)cally;	
  
opera)on	
  reserved	
  as	
  treatment	
  for	
  the	
  
unstable	
  pa)ent	
  
•  1946	
  Harken:	
  Removal	
  of	
  missiles	
  from	
  the	
  
heart	
  during	
  WWII	
  
•  1967	
  Barnard:	
  First	
  heart	
  transplant	
  
Trea)se	
  on	
  cardiac	
  injuries,	
  1927	
  
History	
  
•  1927	
  Djanelidze:	
  published	
  detailed	
  review	
  of	
  
535	
  cases	
  of	
  cardiac	
  injuries	
  
•  1939	
  Bigger:	
  pericardiocentesis	
  should	
  be	
  
used	
  both	
  diagnos)cally	
  and	
  therapeu)cally;	
  
opera)on	
  reserved	
  as	
  treatment	
  for	
  the	
  
unstable	
  pa)ent	
  
•  1946	
  Harken:	
  Removal	
  of	
  missiles	
  from	
  the	
  
heart	
  during	
  WWII	
  
•  1967	
  Barnard:	
  First	
  heart	
  transplant	
  
History	
  
•  1927	
  Djanelidze:	
  published	
  detailed	
  review	
  of	
  
535	
  cases	
  of	
  cardiac	
  injuries	
  
•  1939	
  Bigger:	
  pericardiocentesis	
  should	
  be	
  
used	
  both	
  diagnos)cally	
  and	
  therapeu)cally;	
  
opera)on	
  reserved	
  as	
  treatment	
  for	
  the	
  
unstable	
  pa)ent	
  
•  1946	
  Harken:	
  Removal	
  of	
  missiles	
  from	
  the	
  
heart	
  during	
  WWII	
  
•  1967	
  Barnard:	
  First	
  heart	
  transplant	
  
History	
  
•  1927	
  Djanelidze:	
  published	
  detailed	
  review	
  of	
  
535	
  cases	
  of	
  cardiac	
  injuries	
  
•  1939	
  Bigger:	
  pericardiocentesis	
  should	
  be	
  
used	
  both	
  diagnos)cally	
  and	
  therapeu)cally;	
  
opera)on	
  reserved	
  as	
  treatment	
  for	
  the	
  
unstable	
  pa)ent	
  
•  1946	
  Harken:	
  Removal	
  of	
  missiles	
  from	
  the	
  
heart	
  during	
  WWII	
  
•  1967	
  Barnard:	
  First	
  heart	
  transplant	
  
Lots	
  of	
  Papers	
  
•  Beall	
  AC,	
  Oschner	
  JL,	
  Morris	
  GC	
  Jr,	
  et	
  al.	
  Penetra)ng	
  wounds	
  of	
  the	
  heart.	
  
J	
  Trauma	
  1961;1:195–207.	
  	
  
•  Beall	
  AC,	
  Crosthait	
  RW,	
  Crawford	
  ES,	
  DeBakey	
  ME.	
  Gunshot	
  wounds	
  of	
  the	
  
chest:	
  a	
  plea	
  for	
  individualiza)on.	
  J	
  Trauma	
  1964;	
  4:382–389.	
  	
  
•  Beall	
  AC,	
  Diethrich	
  EB,	
  Crawford	
  HW,	
  et	
  al.	
  Surgical	
  management	
  of	
  
penetra)ng	
  cardiac	
  injuries.	
  Am	
  Surg	
  1966;112:686–	
  692.	
  	
  
•  Boyd	
  TF,	
  Strieder	
  JW.	
  Immediate	
  surgery	
  for	
  trauma)c	
  heart	
  disease.	
  J	
  
Thorac	
  Cardiovasc	
  Surg	
  1965;50:305–315.	
  	
  
•  Sugg	
  WL,	
  Rea	
  WJ,	
  Ecker	
  RR,	
  et	
  al.	
  Penetra)ng	
  wounds	
  of	
  the	
  heart:	
  an	
  
analysis	
  of	
  459	
  cases.	
  J	
  Thorac	
  Cardiovasc	
  Surg	
  1968;	
  56:531–545.	
  	
  
•  MaMox	
  KL,	
  Feliciano	
  DV.	
  Role	
  of	
  external	
  cardiac	
  compression	
  in	
  truncal	
  
trauma.	
  J	
  Trauma	
  1982;22:934–936.	
  	
  
•  Millikan	
  JS,	
  Moore	
  EE.	
  Outcome	
  of	
  resuscita)ve	
  thoracotomy	
  and	
  
descending	
  aor)c	
  occlusion	
  performed	
  in	
  the	
  opera)ng	
  room.	
  J	
  Trauma	
  
1984;24:387–392.	
  	
  
The	
  Current	
  Genera)on	
  
•  Most	
  data	
  is	
  from	
  civilian	
  studies	
  
•  Most	
  data	
  is	
  retrospec)ve	
  
•  There	
  is	
  one	
  major	
  study	
  looking	
  at	
  RT	
  in	
  the	
  
combat	
  zone	
  
	
  
•  Prospec)ve	
  
•  Analyzed	
  mul)ple	
  parameters	
  as	
  predictors	
  of	
  
mortality	
  
–  measured	
  in	
  the	
  field,	
  during	
  transport,	
  and	
  upon	
  
arrival	
  	
  
•  Interven)ons	
  included	
  thoracotomy,	
  sternotomy,	
  
or	
  both,	
  for	
  resuscita)on	
  and	
  defini)ve	
  repair	
  of	
  
cardiac	
  injury	
  
–  ED	
  thoracotomy	
  performed	
  on	
  all	
  pa)ents	
  arriving	
  in	
  
cardiopulmonary	
  arrest	
  
•  Retrospec)ve	
  review	
  of	
  950	
  EDTs	
  performed	
  
at	
  a	
  single	
  regional	
  Level	
  I	
  trauma	
  center	
  over	
  
23	
  years	
  	
  
•  Evaluate	
  the	
  outcome	
  based	
  on	
  the	
  presence	
  
or	
  absence	
  of	
  vital	
  signs	
  	
  
– At	
  first	
  contact	
  by	
  the	
  paramedics	
  and	
  upon	
  
arrival	
  at	
  the	
  emergency	
  department	
  	
  
•  Overall	
  survival	
  4.4%	
  	
  
•  Determine	
  the	
  main	
  factors	
  that	
  most	
  
influence	
  survival	
  aXer	
  EDT	
  	
  
•  24	
  studies,	
  4,620	
  cases,	
  blunt	
  and	
  penetra)ng	
  
trauma	
  	
  
•  Primary	
  outcome	
  analyzed:	
  in-­‐hospital	
  
survival	
  rate	
  	
  
•  Overall	
  survival	
  rate	
  of	
  7.4%	
  
–  Normal	
  neurologic	
  outcomes	
  in	
  92.4%	
  	
  
•  Survival	
  rates:	
  8.8%	
  for	
  penetra)ng	
  and	
  1.4%	
  for	
  
blunt	
  	
  
–  16.8%	
  for	
  stab	
  wounds	
  
–  4.3%	
  for	
  gunshot	
  wounds	
  
–  19.4%	
  if	
  the	
  heart	
  was	
  injured	
  
•  SOL	
  present	
  on	
  arrival:	
  	
  survival	
  11.5%	
  
•  SOL	
  not	
  present	
  on	
  arrival:	
  survival	
  2.6%	
  
•  Prospec)ve	
  and	
  retrospec)ve	
  observa)onal	
  
study	
  	
  
•  Evaluate	
  performance	
  of	
  EDT	
  in	
  order	
  to	
  
improve	
  treatment	
  guidelines	
  	
  
•  Determine	
  the	
  outcomes	
  of	
  any	
  survivors	
  	
  
•  All	
  pa)ents	
  undergoing	
  EDT	
  at	
  a	
  CSH	
  in	
  Iraq	
  
from	
  November	
  2003	
  to	
  December	
  2007	
  
•  RT	
  performed	
  as	
  a	
  primary	
  interven)on	
  
before	
  the	
  pa)ent	
  leX	
  the	
  ER	
  
•  	
  101	
  pa)ents	
  
– 0.01%	
  of	
  total	
  trauma	
  admissions	
  	
  
– 53	
  US	
  military	
  or	
  civilian	
  
– 48	
  host	
  na)onal	
  pa)ents	
  	
  
CPG	
  Review	
  
Algorithms	
  
•  Characterize	
  the	
  physiologic	
  impact	
  of	
  aor)c	
  
balloon	
  occlusion	
  in	
  a	
  model	
  of	
  torso	
  
hemorrhage	
  and	
  shock	
  	
  
•  Compare	
  the	
  effec)veness	
  of	
  this	
  technique	
  
to	
  thoracotomy	
  with	
  aor)c	
  clamping	
  	
  
References	
  
•  Rhee	
  PM,	
  Acosta	
  J,	
  Bridgeman	
  A,	
  et	
  al.	
  Survival	
  aXer	
  emergency	
  department	
  
thoracotomy.	
  J	
  Am	
  Coll	
  Surg.	
  2000;190(3):	
  288-­‐98	
  
•  Edens	
  JW,	
  Beekley	
  AC,	
  Chung	
  KK,	
  Cox	
  ED,	
  Eastridge	
  BJ,	
  Holcomb	
  JB,	
  Blackbourne	
  
LH.	
  Longterm	
  outcomes	
  aXer	
  combat	
  casualty	
  emergency	
  department	
  
thoracotomy.	
  J	
  Am	
  Coll	
  Surg.	
  2009;209:188-­‐197	
  	
  
•  Moore	
  EE,	
  Knudson	
  MM,	
  Burlew	
  CC,	
  et	
  al.	
  Defining	
  the	
  limits	
  of	
  resuscita)ve	
  
emergency	
  department	
  thoracotomy:	
  a	
  contemporary	
  Western	
  Trauma	
  
Associa)on	
  perspec)ve.	
  J	
  Trauma.	
  2011;70(2):334-­‐9	
  	
  
•  Asensio	
  JA,	
  Berne	
  JD,	
  Demetriades	
  D,	
  et	
  al.	
  One	
  hundred	
  five	
  penetra)ng	
  cardiac	
  
injuries:	
  a	
  2-­‐year	
  prospec)ve	
  evalua)on.	
  J	
  Trauma	
  1998;44:1073–1082	
  	
  
•  Branney	
  SW,	
  Moore	
  EE,	
  Feldhaus	
  KM	
  et	
  al.	
  '	
  Cri)cal	
  analysis	
  of	
  two	
  decades	
  of	
  
experience	
  with	
  pos)njury	
  emergency	
  department	
  thoracotomy	
  in	
  a	
  regional	
  
trauma	
  center'.	
  J	
  Trauma	
  1998;45:87-­‐95	
  
•  White,	
  JM,	
  	
  Cannon,	
  JW,	
  Stannard,	
  A,	
  	
  Markov,	
  NP,	
  	
  Spencer,	
  JR,	
  Rasmussen,	
  TE.	
  
Endovascular	
  balloon	
  occlusion	
  of	
  the	
  aorta	
  is	
  superior	
  to	
  resuscita)ve	
  
thoracotomy	
  with	
  aor)c	
  clamping	
  in	
  a	
  porcine	
  model	
  of	
  hemorrhagic	
  shock.	
  
Surgery	
  2011;	
  150(3):400-­‐409	
  

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Resuscitative thoracotomy

  • 1. Resuscita)ve  Thoracotomy   Michael  Meyer,  M.D.,  FACS   COL,  MC   Madigan  Army  Medical  Center  
  • 2.
  • 3. Introduc)on   •  History   •  Studies   •  Review  of  CPG  
  • 4. Requisite  Quotes   1883  Theodore  Bilroth   “The  surgeon  who   should  aMempt  to  suture   a  wound  of  the  heart   would  lose  the  respect  of   his  collegues.”    
  • 5. Requisite  Quotes     1896  James  Paget   “Surgery  of  the  heart  has   probably  reached  the   limits  set  by  nature  to  all   surgery:  no  new  method   and  no  new  discovery  can   overcome  the  natural   difficul)es  that  aMend  a   wound  of  the  heart.”  
  • 6.
  • 7. History   •  1649  Riolanus:  First  described   pericardiocentesis   •  1829  Larrey:  First  successful   pericardiocentesis  for  trauma   •  1896  Rehn:  First  successful  human  cardiac   repair  aXer  a  knife  wound  to  the  RV   •  1901  Igelsrund:  First  open  cardiac  massage  for   cardiac  arrest   •  1902  Hill:  First  cardiorrhaphy  in  the  US    
  • 8. History   •  1649  Riolanus:  First  described   pericardiocentesis   •  1829  Larrey:  First  successful   pericardiocentesis  for  trauma   •  1896  Rehn:  First  successful  human  cardiac   repair  aXer  a  knife  wound  to  the  RV   •  1901  Igelsrund:  First  open  cardiac  massage  for   cardiac  arrest   •  1902  Hill:  First  cardiorrhaphy  in  the  US    
  • 9.
  • 10. History   •  1649  Riolanus:  First  described   pericardiocentesis   •  1829  Larrey:  First  successful   pericardiocentesis  for  trauma   •  1896  Rehn:  First  successful  human  cardiac   repair  aXer  a  knife  wound  to  the  RV   •  1901  Igelsrund:  First  open  cardiac  massage  for   cardiac  arrest   •  1902  Hill:  First  cardiorrhaphy  in  the  US    
  • 11.
  • 12. History   •  1649  Riolanus:  First  described   pericardiocentesis   •  1829  Larrey:  First  successful   pericardiocentesis  for  trauma   •  1896  Rehn:  First  successful  human  cardiac   repair  aXer  a  knife  wound  to  the  RV   •  1901  Igelsrund:  First  open  cardiac  massage  for   cardiac  arrest   •  1902  Hill:  First  cardiorrhaphy  in  the  US    
  • 14. History   •  1649  Riolanus:  First  described   pericardiocentesis   •  1829  Larrey:  First  successful   pericardiocentesis  for  trauma   •  1896  Rehn:  First  successful  human  cardiac   repair  aXer  a  knife  wound  to  the  RV   •  1901  Igelsrund:  First  open  cardiac  massage  for   cardiac  arrest   •  1902  Hill:  First  cardiorrhaphy  in  the  US    
  • 15.
  • 16. History   •  1927  Djanelidze:  published  detailed  review  of   535  cases  of  cardiac  injuries   •  1939  Bigger:  pericardiocentesis  should  be   used  both  diagnos)cally  and  therapeu)cally;   opera)on  reserved  as  treatment  for  the   unstable  pa)ent   •  1946  Harken:  Removal  of  missiles  from  the   heart  during  WWII   •  1967  Barnard:  First  heart  transplant  
  • 17. Trea)se  on  cardiac  injuries,  1927  
  • 18. History   •  1927  Djanelidze:  published  detailed  review  of   535  cases  of  cardiac  injuries   •  1939  Bigger:  pericardiocentesis  should  be   used  both  diagnos)cally  and  therapeu)cally;   opera)on  reserved  as  treatment  for  the   unstable  pa)ent   •  1946  Harken:  Removal  of  missiles  from  the   heart  during  WWII   •  1967  Barnard:  First  heart  transplant  
  • 19. History   •  1927  Djanelidze:  published  detailed  review  of   535  cases  of  cardiac  injuries   •  1939  Bigger:  pericardiocentesis  should  be   used  both  diagnos)cally  and  therapeu)cally;   opera)on  reserved  as  treatment  for  the   unstable  pa)ent   •  1946  Harken:  Removal  of  missiles  from  the   heart  during  WWII   •  1967  Barnard:  First  heart  transplant  
  • 20.
  • 21. History   •  1927  Djanelidze:  published  detailed  review  of   535  cases  of  cardiac  injuries   •  1939  Bigger:  pericardiocentesis  should  be   used  both  diagnos)cally  and  therapeu)cally;   opera)on  reserved  as  treatment  for  the   unstable  pa)ent   •  1946  Harken:  Removal  of  missiles  from  the   heart  during  WWII   •  1967  Barnard:  First  heart  transplant  
  • 22. Lots  of  Papers   •  Beall  AC,  Oschner  JL,  Morris  GC  Jr,  et  al.  Penetra)ng  wounds  of  the  heart.   J  Trauma  1961;1:195–207.     •  Beall  AC,  Crosthait  RW,  Crawford  ES,  DeBakey  ME.  Gunshot  wounds  of  the   chest:  a  plea  for  individualiza)on.  J  Trauma  1964;  4:382–389.     •  Beall  AC,  Diethrich  EB,  Crawford  HW,  et  al.  Surgical  management  of   penetra)ng  cardiac  injuries.  Am  Surg  1966;112:686–  692.     •  Boyd  TF,  Strieder  JW.  Immediate  surgery  for  trauma)c  heart  disease.  J   Thorac  Cardiovasc  Surg  1965;50:305–315.     •  Sugg  WL,  Rea  WJ,  Ecker  RR,  et  al.  Penetra)ng  wounds  of  the  heart:  an   analysis  of  459  cases.  J  Thorac  Cardiovasc  Surg  1968;  56:531–545.     •  MaMox  KL,  Feliciano  DV.  Role  of  external  cardiac  compression  in  truncal   trauma.  J  Trauma  1982;22:934–936.     •  Millikan  JS,  Moore  EE.  Outcome  of  resuscita)ve  thoracotomy  and   descending  aor)c  occlusion  performed  in  the  opera)ng  room.  J  Trauma   1984;24:387–392.    
  • 23. The  Current  Genera)on   •  Most  data  is  from  civilian  studies   •  Most  data  is  retrospec)ve   •  There  is  one  major  study  looking  at  RT  in  the   combat  zone    
  • 24. •  Prospec)ve   •  Analyzed  mul)ple  parameters  as  predictors  of   mortality   –  measured  in  the  field,  during  transport,  and  upon   arrival     •  Interven)ons  included  thoracotomy,  sternotomy,   or  both,  for  resuscita)on  and  defini)ve  repair  of   cardiac  injury   –  ED  thoracotomy  performed  on  all  pa)ents  arriving  in   cardiopulmonary  arrest  
  • 25.
  • 26. •  Retrospec)ve  review  of  950  EDTs  performed   at  a  single  regional  Level  I  trauma  center  over   23  years     •  Evaluate  the  outcome  based  on  the  presence   or  absence  of  vital  signs     – At  first  contact  by  the  paramedics  and  upon   arrival  at  the  emergency  department     •  Overall  survival  4.4%    
  • 27.
  • 28. •  Determine  the  main  factors  that  most   influence  survival  aXer  EDT     •  24  studies,  4,620  cases,  blunt  and  penetra)ng   trauma     •  Primary  outcome  analyzed:  in-­‐hospital   survival  rate    
  • 29. •  Overall  survival  rate  of  7.4%   –  Normal  neurologic  outcomes  in  92.4%     •  Survival  rates:  8.8%  for  penetra)ng  and  1.4%  for   blunt     –  16.8%  for  stab  wounds   –  4.3%  for  gunshot  wounds   –  19.4%  if  the  heart  was  injured   •  SOL  present  on  arrival:    survival  11.5%   •  SOL  not  present  on  arrival:  survival  2.6%  
  • 30. •  Prospec)ve  and  retrospec)ve  observa)onal   study     •  Evaluate  performance  of  EDT  in  order  to   improve  treatment  guidelines     •  Determine  the  outcomes  of  any  survivors    
  • 31. •  All  pa)ents  undergoing  EDT  at  a  CSH  in  Iraq   from  November  2003  to  December  2007   •  RT  performed  as  a  primary  interven)on   before  the  pa)ent  leX  the  ER   •   101  pa)ents   – 0.01%  of  total  trauma  admissions     – 53  US  military  or  civilian   – 48  host  na)onal  pa)ents    
  • 32.
  • 34.
  • 36. •  Characterize  the  physiologic  impact  of  aor)c   balloon  occlusion  in  a  model  of  torso   hemorrhage  and  shock     •  Compare  the  effec)veness  of  this  technique   to  thoracotomy  with  aor)c  clamping    
  • 37.
  • 38. References   •  Rhee  PM,  Acosta  J,  Bridgeman  A,  et  al.  Survival  aXer  emergency  department   thoracotomy.  J  Am  Coll  Surg.  2000;190(3):  288-­‐98   •  Edens  JW,  Beekley  AC,  Chung  KK,  Cox  ED,  Eastridge  BJ,  Holcomb  JB,  Blackbourne   LH.  Longterm  outcomes  aXer  combat  casualty  emergency  department   thoracotomy.  J  Am  Coll  Surg.  2009;209:188-­‐197     •  Moore  EE,  Knudson  MM,  Burlew  CC,  et  al.  Defining  the  limits  of  resuscita)ve   emergency  department  thoracotomy:  a  contemporary  Western  Trauma   Associa)on  perspec)ve.  J  Trauma.  2011;70(2):334-­‐9     •  Asensio  JA,  Berne  JD,  Demetriades  D,  et  al.  One  hundred  five  penetra)ng  cardiac   injuries:  a  2-­‐year  prospec)ve  evalua)on.  J  Trauma  1998;44:1073–1082     •  Branney  SW,  Moore  EE,  Feldhaus  KM  et  al.  '  Cri)cal  analysis  of  two  decades  of   experience  with  pos)njury  emergency  department  thoracotomy  in  a  regional   trauma  center'.  J  Trauma  1998;45:87-­‐95   •  White,  JM,    Cannon,  JW,  Stannard,  A,    Markov,  NP,    Spencer,  JR,  Rasmussen,  TE.   Endovascular  balloon  occlusion  of  the  aorta  is  superior  to  resuscita)ve   thoracotomy  with  aor)c  clamping  in  a  porcine  model  of  hemorrhagic  shock.   Surgery  2011;  150(3):400-­‐409