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) اللهم علمني ما ينفعني  وانفعني بما علمتني   ( بسم الله الرحمن الرحيم
Arterial Blood Gases This article will help us to ,[object Object],2. Translate informations into effective  action .
Indications ,[object Object],[object Object]
Technique ,[object Object],[object Object],[object Object]
[object Object]
PH  7.35 – 7.45 PaCO 2   35 – 45 mmHg PaO 2   80-100 mmHg HCO 3 22 – 26mq / L   O 2  saturation 95 – 100 % Normal values of ABG,s
Interpretation of ABG,s ,[object Object],If  PH < 7. 35  acidosis If  PH > 7. 45 alkalosis
[object Object],[object Object],[object Object],it is primary  respiratory   acid -  base disturbance . it is primary  metabolic  acid – base disturbance .
PH  PaCO 2 ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],it is acute . ,[object Object],it is chronic . N.B accepted PH is from 7.30 to 7.50 .
Acid – Base Disorder  Primary change  Compensatory change Respiratory acidosis  PaCo 2 HCo 3 Respiratory acidosis Respiratory alkalosis PaCo 2 HCo 3 Metabolic acidosis HCo 3 PaCo 2 Metabolic alkalosis HCo 3 PCo 2
[object Object],. If PaO 2  between 80 – 100 mmHg ,  oxygenation is normal . . If PaO 2  is < 60 mmHg , hypoxic  state is existing .
*In respiratory disturbances  :  .If ABG,s show only that PaO 2  is  < 60 mmHg Hypoxaemic (  type I  )  Respiratory Failure . .If PaO 2  < 60 mmHg & PaCO 2  > 45mmHg, Hypoxaemic , Hypercapnic (  type II )   Respiratory Failure .
Indication for Critical Care Unite admission ,[object Object],2. Severe or worsening hypercapnia  ( PaCO 2  > 70 mmHg ) .  3. Severe or worsening respiratory  acidosis ( PH < 7.30 ) .
Measures to improve ventilation  1. Enhancing alveolar ventilation  i.e treatment of the cause  ( drug over  dose / central hypoventilation /  neuromuscular disease / airway  obstruction ) . 2. Decrease CO 2  production  -Bring fever down .  -Avoid excessive nutritional calories .
Measures to improve oxygenation ,[object Object],[object Object],[object Object]
2.  Treatment  of the cause .  3. Anaemic patients should be  transfused to haemoglobin of 10 gm % .
adequate delivery  of oxygenated blood to tissues .  4. Hypotensive patients should be resuscitated to an adequate cardiac output to assure
EXAMPLE 1   PH  7.34  (academia ) Pa CO2  48  ( academia ) Pa O2  129  ( normal ) HCO3 –  26  ( normal ) BE  + 1  ( normal ) Sa O 2  99 %  ( normal ) Interpretation  Respiratory acidosis , adequate oxygenation.
EXAMPLE 2   PH  7.40  ( normal ) Pa CO2  58  ( academia ) Pa O2  57  ( hypoxemia ) HCO3 –  35  ( alkalemia  ) BE  + 9  ( alkalemia ) Sa O 2  89 %  ( hypoxemia ) Interpretation  Respiratory acidosis with complete metabolic compensation and hypoxemia .
EXAMPLE 3   PH  7.29  (academia ) Pa CO2  40  ( normal ) Pa O2  192  ( normal ) HCO3 –  19  (academia ) BE  - 5.6  (academia ) Sa O 2  97.5 %  ( normal  ) Interpretation  Metabolic acidosis with no compensation , adequate oxygenation.
EXAMPLE 4   PH  7.37  ( normal ) Pa CO2  40  ( normal ) Pa O2  126  ( academia ) HCO3 –  20  ( academia ) BE  - 3.1  ( academia) Sa O 2  98 %  ( normal  ) Interpretation  Fully compensated metabolic acidosis , adequate oxygenation.
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Interpreting ABGs

  • 1. ) اللهم علمني ما ينفعني وانفعني بما علمتني ( بسم الله الرحمن الرحيم
  • 2.
  • 3.
  • 4.
  • 5.
  • 6. PH 7.35 – 7.45 PaCO 2 35 – 45 mmHg PaO 2 80-100 mmHg HCO 3 22 – 26mq / L O 2 saturation 95 – 100 % Normal values of ABG,s
  • 7.
  • 8.
  • 9.
  • 10.
  • 11. Acid – Base Disorder Primary change Compensatory change Respiratory acidosis PaCo 2 HCo 3 Respiratory acidosis Respiratory alkalosis PaCo 2 HCo 3 Metabolic acidosis HCo 3 PaCo 2 Metabolic alkalosis HCo 3 PCo 2
  • 12.
  • 13. *In respiratory disturbances : .If ABG,s show only that PaO 2 is < 60 mmHg Hypoxaemic ( type I ) Respiratory Failure . .If PaO 2 < 60 mmHg & PaCO 2 > 45mmHg, Hypoxaemic , Hypercapnic ( type II ) Respiratory Failure .
  • 14.
  • 15. Measures to improve ventilation 1. Enhancing alveolar ventilation i.e treatment of the cause ( drug over dose / central hypoventilation / neuromuscular disease / airway obstruction ) . 2. Decrease CO 2 production -Bring fever down . -Avoid excessive nutritional calories .
  • 16.
  • 17. 2. Treatment of the cause . 3. Anaemic patients should be transfused to haemoglobin of 10 gm % .
  • 18. adequate delivery of oxygenated blood to tissues . 4. Hypotensive patients should be resuscitated to an adequate cardiac output to assure
  • 19. EXAMPLE 1 PH 7.34 (academia ) Pa CO2 48 ( academia ) Pa O2 129 ( normal ) HCO3 – 26 ( normal ) BE + 1 ( normal ) Sa O 2 99 % ( normal ) Interpretation Respiratory acidosis , adequate oxygenation.
  • 20. EXAMPLE 2 PH 7.40 ( normal ) Pa CO2 58 ( academia ) Pa O2 57 ( hypoxemia ) HCO3 – 35 ( alkalemia ) BE + 9 ( alkalemia ) Sa O 2 89 % ( hypoxemia ) Interpretation Respiratory acidosis with complete metabolic compensation and hypoxemia .
  • 21. EXAMPLE 3 PH 7.29 (academia ) Pa CO2 40 ( normal ) Pa O2 192 ( normal ) HCO3 – 19 (academia ) BE - 5.6 (academia ) Sa O 2 97.5 % ( normal ) Interpretation Metabolic acidosis with no compensation , adequate oxygenation.
  • 22. EXAMPLE 4 PH 7.37 ( normal ) Pa CO2 40 ( normal ) Pa O2 126 ( academia ) HCO3 – 20 ( academia ) BE - 3.1 ( academia) Sa O 2 98 % ( normal ) Interpretation Fully compensated metabolic acidosis , adequate oxygenation.