Answer The V, D and J gene are rearranged in an order during B-cell.pdf

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Answer: The V, D and J gene are rearranged in an order during B-cell differentiation. Firstly, D to JH joining takes place followed by V to DJH joining. Recombinant signal sequence mediate such rearrangements. The inactivation of DH1 JH1 rearrangement is found mainly in patients with multiple myeloma. Also, detection of minimal residual diseases is seen in such cases. The VH1 inactivation leads to affect purines compared to pyrimidines leading to mutation and interference of nucleic acid synthesis. T cell receptor V beta gene families are used by lymphocytes which affect the hyperglycemic condition and beta cell destruction. The inactivation of Vbeta3 may lead to control of diabetes. The Dbeta3 deactivation is found in patients with leukemia. This deactivations may lead to an immunodeficient phenotype. RAG2 function inactivation leads to inability of rearrangement of V, D ad H gene. This inactivation also leads to impaired development of lymphocytes with reduced chromosomal V(D)J recombination. Solution Answer: The V, D and J gene are rearranged in an order during B-cell differentiation. Firstly, D to JH joining takes place followed by V to DJH joining. Recombinant signal sequence mediate such rearrangements. The inactivation of DH1 JH1 rearrangement is found mainly in patients with multiple myeloma. Also, detection of minimal residual diseases is seen in such cases. The VH1 inactivation leads to affect purines compared to pyrimidines leading to mutation and interference of nucleic acid synthesis. T cell receptor V beta gene families are used by lymphocytes which affect the hyperglycemic condition and beta cell destruction. The inactivation of Vbeta3 may lead to control of diabetes. The Dbeta3 deactivation is found in patients with leukemia. This deactivations may lead to an immunodeficient phenotype. RAG2 function inactivation leads to inability of rearrangement of V, D ad H gene. This inactivation also leads to impaired development of lymphocytes with reduced chromosomal V(D)J recombination..

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The two commands are used to verify NAT configuration are1) Router.pdf

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There exists two types of circulatory path in cardivascular system: 1. Pulmonary circulation and systemic circulation. Both of them differ in carrying deoxygenated blood and oxygenated blood respectively. In PULMONARY CIRCULATION: deoxygenated blood is carried from heart to lungs. When oxygen depleted blood enters right atrium and then through tricuspib valve, enters right ventricle, From there blood gets pumped into pulnonary artery , which carries blood to the lungs. In the lungs Carbon dioxide is released and oxygen is absorbed by blood. Alveolar sacs present in lungs provide surface for gaseous exchange. . Then oxygenated blood is carried by Pulmonary veins to the left atrium. In SYSTEMIC CIRCULATION blood is carried from heart to all parts of the body and provides oxygen and nutrients. oxygenated blood enters left atrium, when it leaves the pulmonary circulation, and then enters left ventricle through mitral valve. then blood enters aorta, ehich branches into arteris and carries blood throughout the body. Solution There exists two types of circulatory path in cardivascular system: 1. Pulmonary circulation and systemic circulation. Both of them differ in carrying deoxygenated blood and oxygenated blood respectively. In PULMONARY CIRCULATION: deoxygenated blood is carried from heart to lungs. When oxygen depleted blood enters right atrium and then through tricuspib valve, enters right ventricle, From there blood gets pumped into pulnonary artery , which carries blood to the lungs. In the lungs Carbon dioxide is released and oxygen is absorbed by blood. Alveolar sacs present in lungs provide surface for gaseous exchange. . Then oxygenated blood is carried by Pulmonary veins to the left atrium. In SYSTEMIC CIRCULATION blood is carried from heart to all parts of the body and provides oxygen and nutrients. oxygenated blood enters left atrium, when it leaves the pulmonary circulation, and then enters left ventricle through mitral valve. then blood enters aorta, ehich branches into arteris and carries blood throughout the body..

There exists two types of circulatory path in cardivascular system .pdf

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The photosystems found in the thylakoid membrane of the plants are the structural and functional unit of photosynthesis. Purple bacteria has a single photosystem with bacteriochlorophyl. They do not produce oxygen while doing photosynthesis. ATP production occurs via cyclic photophosphorylation. Their electron donor is elemental sulfur. Green Bacteria- undergo anoxigenic phototrophy. They also possess a single photosystem with bacteriochlorophyl.. ATP is produced by cyclic photophosphorylation. Electron donor is thiosulfare or H2S. Alters the ATP or NADH. Cyanobacteria- Has 2 different photosystems and reaction centres. They undergo oxygenic phototrophy. They fix CO2, and generate ATP and reducing power in a single process. They have a similar process of photosynthesis as plants. The electrons passes through the electron transpot chain fro photosystem I to photosystemII. And ultimately NADPH+ prodeces from NADP+. Solution The photosystems found in the thylakoid membrane of the plants are the structural and functional unit of photosynthesis. Purple bacteria has a single photosystem with bacteriochlorophyl. They do not produce oxygen while doing photosynthesis. ATP production occurs via cyclic photophosphorylation. Their electron donor is elemental sulfur. Green Bacteria- undergo anoxigenic phototrophy. They also possess a single photosystem with bacteriochlorophyl.. ATP is produced by cyclic photophosphorylation. Electron donor is thiosulfare or H2S. Alters the ATP or NADH. Cyanobacteria- Has 2 different photosystems and reaction centres. They undergo oxygenic phototrophy. They fix CO2, and generate ATP and reducing power in a single process. They have a similar process of photosynthesis as plants. The electrons passes through the electron transpot chain fro photosystem I to photosystemII. And ultimately NADPH+ prodeces from NADP+..

The photosystems found in the thylakoid membrane of the plants are t.pdf

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The diplococci bacteria are round-shaped microbes, and occur in the form of cell pairs. Gram- negative is a term used in association with these bacteria, which means that a crystal violet dye is not retained (in the protocol of Gram staining) by these organisms. Those bacteria, which retain this dye are known as gram positive. Neisseria Meningitidis: It is amongst the most important gram negative diplococci, and is responsible for causing meningitis. . It is a leading cause of fatal bacterial meningitis . Meningitis may be accompanied by appearance of petechiae (rash) that is associated with meningococcal bacteremia (i.e.,meningococemia). Symptoms Early meningitis symptoms may mimic the flu (influenza). Symptoms may develop over several hours or over a few days. Possible signs and symptoms in anyone older than the age of 2 include: · Sudden high fever · Stiff neck · Severe headache that seems different than normal · Headache with nausea or vomiting · Confusion or difficulty concentrating · Seizures · Sleepiness or difficulty waking · Sensitivity to light · No appetite or thirst · Skin rash (sometimes, such as in meningococcal meningitis) Doctor will also order a lumbar puncture. This test is also called a spinal tap. It allows your doctor to look for increased pressure in the central nervous system. It can also find inflammation or bacteria in the spinal fluid. This test can also help determine the best antibiotic for treatment. Bacterial meningitis requires immediate hospitalization. Early diagnosis and treatment will prevent brain damage and death. Bacterial meningitis is treated with intravenous antibiotics. There’s no specific antibiotic for bacterial meningitis. It depends on the bacteria involved. Solution The diplococci bacteria are round-shaped microbes, and occur in the form of cell pairs. Gram- negative is a term used in association with these bacteria, which means that a crystal violet dye is not retained (in the protocol of Gram staining) by these organisms. Those bacteria, which retain this dye are known as gram positive. Neisseria Meningitidis: It is amongst the most important gram negative diplococci, and is responsible for causing meningitis. . It is a leading cause of fatal bacterial meningitis . Meningitis may be accompanied by appearance of petechiae (rash) that is associated with meningococcal bacteremia (i.e.,meningococemia). Symptoms Early meningitis symptoms may mimic the flu (influenza). Symptoms may develop over several hours or over a few days. Possible signs and symptoms in anyone older than the age of 2 include: · Sudden high fever · Stiff neck · Severe headache that seems different than normal · Headache with nausea or vomiting · Confusion or difficulty concentrating · Seizures · Sleepiness or difficulty waking · Sensitivity to light · No appetite or thirst · Skin rash (sometimes, such as in meningococcal meningitis) Doctor will also order a lumbar puncture. This test is also called a spinal tap. It allows your do.

The diplococci bacteria are round-shaped microbes, and occur in the .pdf

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Technology may be defined as an innovation that can help for a person to create a easy things out of difficuilt tasks. Actually technology comparises invention, modelling and diffusion out of raw things. Technological advancement is change in certain things like cars mobiles etc so as to make life easier and easier. Technology helps in progress of business, communication with people and helps in economic development of mankind. We purchase new things with new innovations to help ourselves to make certain things easier. Technological development has helped us to provide better mind development so as one is able to gain knowledge more accurately. Technological development has grown faster and faster day by day to bring out/help people in their day by day life. Technological development has created huge advancement in communication skills. In 19th and 20th century communication was not too much developed but during 21st century there was drastic advancement in communication. People living in different parts of world were communicating and as such it was like they are close to each other in a single room talking. one of the best technological development is mobile phones/ smart phones, with the help of these person is able to locate other people, talk to them even if they are far away, can have knowledge of certain things in no time, can get knowledge what’s happening in different parts of world. This has provided a change and advancement in technology (video calling, live calling etc). Secondly, we have Mobile ad hoc network that has changed into vehicular networks where we can have security part in our vehicles. In VANET network technology has drastically changed into numerous amount of innovations. In this network where people can communicate to the different vehicles and to locate other vehicles in different cities. VANETs will be surely the largest real life example of a self maintained ad hoc network, if implemented rightly. Each node in a specific size has got certain properties which can be defined like service providers, attackers and authorities. Here in this technology you can see the advancement in technology of vehicles which we don’t see them in past years. Public safety applications, Curve speed warning, Turn assistance, Collision Warning. Through this technology one can have intervehicular communication that has got lot of features which communicating each other. Basically it is the need of people and environment and new researches that drives the technology, to bring it up to the heights where people can find it easier than earlier. Cure for diseases have provided new changes in technology as it has provided easier way to treat patients. Now people are easily treated with lesser pain, more accurately and thus technology has provided better quality treatments with less pain. Due to progress in technology operations have become less as this painful treatment has been replaced by laser treatment, humans have been replaced by robots .

Technology may be defined as an innovation that can help for a perso.pdf

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The actual illustration of values is decided by the machine design (strictly speaking, by the C implementation). the particular size is accessed through the itemsize attribute. The values hold on for \'L\' and \'I\' things are diagrammatical as Python long integers once retrieved, as a result of Python’s plain number sort cannot represent the complete vary of C’s unsigned (long) integers. The module defines the subsequent type: class array.array(typecode[, initializer]) A new array whose things ar restricted by typecode, and initialized from the nonmandatory initializer worth, that should be a listing, string, or iterable over components of the acceptable sort. Changed in version two.4: at one time, solely lists or strings were accepted. If given a listing or string, the initializer is passed to the new array’s fromlist(), fromstring(), or fromunicode() methodology (see below) to feature initial things to the array. Otherwise, the iterable initializer is passed to the extend() methodology. array.ArrayType Obsolete alias for array. Array objects support the normal sequence operations of assortment, slicing, concatenation, and multiplication. once mistreatment slice assignment, the assigned worth should be Associate in Nursing array object with an equivalent sort code; all told alternative cases, TypeError is raised. Array objects additionally implement the buffer interface, and should be used where buffer objects ar supported. The following information things and ways also are supported: array.typecode The typecode character wont to produce the array. array.itemsize The length in bytes of 1 array item within the representation. array.append(x) Append a replacement item with worth x to the tip of the array. array.buffer_info() Return a tuple (address, length) giving the present memory address and also the length in components of the buffer wont to hold array’s contents. the dimensions of the memory buffer in bytes is computed as array.buffer_info()[1] * array.itemsize. this can be often helpful once operating with low-level (and inherently unsafe) I/O interfaces that need memory addresses, like bound ioctl() operations. The came back numbers ar valid as long because the array exists and no length-changing operations ar applied thereto. Note once mistreatment array objects from code written in C or C++ (the solely thanks to effectively create use of this information), it makes a lot of sense to use the buffer interface supported by array objects. This methodology is maintained for backward compatibility and may be avoided in new code. The buffer interface is documented in Buffers and Memoryview Objects. array.byteswap() “Byteswap” all things of the array. this can be solely supported for values that ar one, 2, 4, or eight bytes in size; for alternative sorts of values, RuntimeError is raised. it\'s helpful once reading information from a file written on a machine with a unique computer memory unit order. array.count(x) Return the amount of occur.

The actual illustration of values is decided by the machine design (.pdf

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Solution i.e. m is bounded sequence.To find m for which the oper.pdf

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Roll up is a type of merger where the investors in the market buy 2 or more companies and merge them up or roll up to enjoy economies of scale and reduce costs. The companies in merger are generally small companies. 2. Advantages of roll up are: a. Provides instant growth in terms of instant risks and rewards to investors due to the synergies achieved by the merger. B. Eliminate the competitors in the market due to some of horizontal and vertical mergers I.e. moving up or down the supply chain. C. Surprise and challenge the competitors in the market. 3. Disadvantages of roll up are: A. Integration risk is an important issue when it comes to the integration of operations of two businesses. B. Increased cost, sometimes the cost of synergies doesn\'t outweigh the benefits of merger. C. Cultural issues are also important to address of the merging companies. 4. The recent successful roll up example is of Valeant Pharmaceuticals International Inc. based in Canada. This company grew rapidly with a series of mergers and acquisitions under the leadership of J. Michael Pearson and in 2015 it was the most valuable company in Canada. It accquire Salix Pharmaceutical for 14.5$ billion in 2015. Solution Roll up is a type of merger where the investors in the market buy 2 or more companies and merge them up or roll up to enjoy economies of scale and reduce costs. The companies in merger are generally small companies. 2. Advantages of roll up are: a. Provides instant growth in terms of instant risks and rewards to investors due to the synergies achieved by the merger. B. Eliminate the competitors in the market due to some of horizontal and vertical mergers I.e. moving up or down the supply chain. C. Surprise and challenge the competitors in the market. 3. Disadvantages of roll up are: A. Integration risk is an important issue when it comes to the integration of operations of two businesses. B. Increased cost, sometimes the cost of synergies doesn\'t outweigh the benefits of merger. C. Cultural issues are also important to address of the merging companies. 4. The recent successful roll up example is of Valeant Pharmaceuticals International Inc. based in Canada. This company grew rapidly with a series of mergers and acquisitions under the leadership of J. Michael Pearson and in 2015 it was the most valuable company in Canada. It accquire Salix Pharmaceutical for 14.5$ billion in 2015..

Roll up is a type of merger where the investors in the market buy 2 .pdf

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Polymorphism When one assignment is performed by various ways i.e. known as polymorphism. For instance: to persuade the client in an unexpected way, to draw something e.g. shape or rectangle and so on. In java, we utilize strategy over-burdening and technique abrogating to accomplish polymorphism. Another case can be to talk something e.g. feline talks meaw, pooch barks woof and so forth. Reflection Covering up inward subtle elements and demonstrating usefulness is known as reflection. For instance: telephone call, we don\'t have a clue about the inward preparing. In java, we utilize unique class and interface to accomplish reflection. Exemplification Official (or wrapping) code and information together into a solitary unit is known as exemplification. For instance: container, it is wrapped with various medications. A java class is the case of exemplification. Java bean is the completely epitomized class since every one of the information individuals are private here. Favorable position of OOPs over Procedure-situated programming dialect 1)OOPs makes improvement and support less demanding where as in Procedure-arranged programming dialect it is difficult to oversee if code develops as undertaking size develops. 2)OOPs gives information covering up while in Procedure-situated programming dialect a worldwide information can be gotten to from anyplace. 3)OOPs gives capacity to reproduce true occasion substantially more successfully. We can give the arrangement of genuine word issue on the off chance that we are utilizing the Object- Oriented Programming dialect. Worldwide Data Object Data What is distinction between item arranged programming dialect and article based programming dialect? Object based programming dialect tails every one of the elements of OOPs with the exception of Inheritance. JavaScript and VBScript are case of item based programming dialects. Solution Polymorphism When one assignment is performed by various ways i.e. known as polymorphism. For instance: to persuade the client in an unexpected way, to draw something e.g. shape or rectangle and so on. In java, we utilize strategy over-burdening and technique abrogating to accomplish polymorphism. Another case can be to talk something e.g. feline talks meaw, pooch barks woof and so forth. Reflection Covering up inward subtle elements and demonstrating usefulness is known as reflection. For instance: telephone call, we don\'t have a clue about the inward preparing. In java, we utilize unique class and interface to accomplish reflection. Exemplification Official (or wrapping) code and information together into a solitary unit is known as exemplification. For instance: container, it is wrapped with various medications. A java class is the case of exemplification. Java bean is the completely epitomized class since every one of the information individuals are private here. Favorable position of OOPs over Procedure-situated programming dialect 1)OOPs makes improvement and support less .

PolymorphismWhen one assignment is performed by various ways i.e. .pdf

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Ovary : Each ovary is whitish in colour and located alongside the lateral wall of the uterus in a region called ovarian fossa. The fossa lies beneath the external iliac artery and in front of the ureter and the internal iliac artery. Its size is about 4 x 3 x 32 cm. Uterine horn: They are horns are the points where the uterus and the fallopian tubes meet. They are the attachment point for round ligament of uterus along with mons pubis. Uterus: It is located inside the pelvis dorsal to the urinary bladder and ventral to the rectum. It is pear shaped and 7.6 x 4.5 x 3.0 in dimension. It weighs about 60 gram in adults. Testes: It is located in the scrotm and composed of dense connective tissue. Sperms travel through the testis from the tubules, through network of ducts to the epididymis. epididymus: It is a tube that connects a testicle to a vas deferens. It is 6-7 feet in length. epididymis can be divided into three main regions: The head, the body and the tail. Vas deferens: It is also called ductus deferens. It transport sperm from the epididymis to the ejaculatory ducts. Each tube is about 30 cms long. Seminal vesicle: It is tubular glands posteroinferior to the urinary bladder. It is located with in the pelvis. Prostate gland: It is walnut sized gland located between the bladder and the penis. It is located just in front of the rectum. It scretes fluid that nourishes and protect sperm. Solution Ovary : Each ovary is whitish in colour and located alongside the lateral wall of the uterus in a region called ovarian fossa. The fossa lies beneath the external iliac artery and in front of the ureter and the internal iliac artery. Its size is about 4 x 3 x 32 cm. Uterine horn: They are horns are the points where the uterus and the fallopian tubes meet. They are the attachment point for round ligament of uterus along with mons pubis. Uterus: It is located inside the pelvis dorsal to the urinary bladder and ventral to the rectum. It is pear shaped and 7.6 x 4.5 x 3.0 in dimension. It weighs about 60 gram in adults. Testes: It is located in the scrotm and composed of dense connective tissue. Sperms travel through the testis from the tubules, through network of ducts to the epididymis. epididymus: It is a tube that connects a testicle to a vas deferens. It is 6-7 feet in length. epididymis can be divided into three main regions: The head, the body and the tail. Vas deferens: It is also called ductus deferens. It transport sperm from the epididymis to the ejaculatory ducts. Each tube is about 30 cms long. Seminal vesicle: It is tubular glands posteroinferior to the urinary bladder. It is located with in the pelvis. Prostate gland: It is walnut sized gland located between the bladder and the penis. It is located just in front of the rectum. It scretes fluid that nourishes and protect sperm..

Ovary Each ovary is whitish in colour and located alongside the la.pdf

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