8. Functions
Haemoglobin, a globular protein
green = haem groups
red & blue = protein subunits Heme
Blood performs many important functions within the body
including:
Supply of oxygen to tissues (bound to hemoglobin, which is
carried in red cells)
Supply of nutrients such as glucose, amino acids, and fatty acids
(dissolved in the blood or bound to plasma proteins (e.g.,
blood lipids))
Removal of waste such as carbon dioxide, urea, and lactic acid
I
9. mmunological functions, including circulation of
white blood cells, and detection of foreign material by
antibodies
Coagulation, the response to a broken blood vessel,
the conversion of blood from a liquid to a semi-solid
gel to stop bleeding.
Messenger functions, including the transport of
hormones and the signaling of tissue damage
Regulation of body pH
Regulation of core body temperature
Hydraulic functions
13. Precautions and Adverse
Reactions During Blood
Transfusion
To minimize the chance of an adverse reaction
during a transfusion, health care practitioners
take several precautions. Before starting the
transfusion, usually a few hours or even a
few days beforehand, a technician mixes a
drop of the donor's blood with the recipient's
to make sure they are compatible. This
procedure is called cross-matching.
14. After double-checking labels on the bags of
blood that are about to be given to ensure
the units are intended for that recipient, the
health care practitioner gives the blood to
the recipient slowly, generally over 1 to 2
hours for each unit of blood. Because most
adverse reactions occur during the first 15
minutes of the transfusion, the recipient is
closely observed at first. After that, a nurse
checks on the recipient periodically and
must stop the transfusion if an adverse
reaction occurs.
15. Most transfusions are safe and successful. However, mild reactions
occur occasionally, and, rarely, severe and even fatal reactions may
occur.
The most common reactions, which occur in 1 to 2% of
transfusions, are
Fever
Allergic reactions
The most serious reactions are
Fluid overload
Lung injury
Breakdown of red blood cells due to a mismatch between the
donor's and recipient's blood type
16. DOs and DON'Ts of blood donation
In order to ensure safe and health environment to
both donors as well as recipients, we greatly
recommend to follow the below rules:
DO donate blood, only if you satisfy all of the
following conditions
You are between age group of 18-60 years.
Your weight is 45 kgs or more.
Your hemoglobin is 12.5 gm% minimum.
Your last blood donation was 3 or more months
earlier.
You are healthy and have not suffered from
malaria, typhoid or other transmissible disease in
the recent past.
17. DO NOT donate blood, if you have any of the
following conditions
Cold / fever in the past 1 week.
Under treatment with antibiotics or any other
medication.
Cardiac problems, hypertension, epilepsy, diabetes
(on insulin therapy), history of cancer, chronic kidney
or liver disease, bleeding tendencies, venereal
disease etc.
Major surgery in the last 6 months.
Vaccination in the last 24 hours.
Had a miscarriage in the last 6 months or have been
pregnant / lactating in the last one year.
18. Had fainting attacks during last donation.
Have regularly received treatment with blood products.
Shared a needle to inject drugs/ have history of drug
addiction.
Had sexual relations with different partners or with a
high risk individual.
Been tested positive for antibodies to HIV.