MRCPsych08 - How To Analyse Diagnostic Test Studies (June08)

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This is an educational talk/presentation on the science of diagnostic tests using examples from psychiatry. It was first presented for MRCPsych (Royal College of Psychiatrists UK) June 2008. Now updated in 2009...see newer version

Economy & Finance Health & Medicine

MRCPsych Teaching 2008

Critical Appraisal of Diagnostic Test Studies

Alex J Mitchell
Consultant in Liaison Psychiatry
University of Leicester

Contents
• Importance of understanding diagnostic tests

• Statistics of diagnostic validity

• Examples

Importance of understanding diagnostic tests

What Is a Diagnostic Test in Psychiatry?
• CT/MRI
• CSF
• Blood tests eg TFTs
• SCAN/SCID/PSE/MINI
• Neuropsychological Testing
• MMSE
• HADS/BDI/CESD?
• Clinical Judgement
• Self-report

Why Is a HADS score not a diagnosis?

1. No core features
2. No symptom ranking
3. No functional assessment
4. Duration unclear
5. What if Missing items?
6. Imprecise

MRCPsych08 - How To Analyse Diagnostic Test Studies (June08)

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