Patient Inspired. Outcomes Driven.
PIVOTTO
THEPATIENT
Successive waves of disruption
are reshaping healthcare – at
pace and magnitude.
RIDINGWAVES
OFDISRUPTION
Copyright © 2018 Accenture. All rights reserved. 2
In response to converging forces, life sciences is evol
ving rapidly from selling products at volume to
delivering value through better patient outcomes.
For those ready to seize the opportunity, it’s creating
infinite new possibilities to reinvent the patient
experience and redefine the future of healthcare.
FORCESOFCHANGE
INTODAY’S BUSINESSMODELS
Copyright © 2018 Accenture. All rights reserved. 3
Socio-economic
Trends
+
Healthcare
Consumerization
+
New Science
Landscape
Catalyzed by
Technology, Digital &
Data
Rise in healthcare outstripped rise in GDP by
55% in 2017 in US.*
Payors are demanding proof of improved
patient outcomes—value-based contracts
have nearly tripled since 2006.
THEECONOMICS
DON’TLINEUP
Copyright © 2018 Accenture. All rights reserved. 4
SOCIO-ECONOMICTRENDS
*Source: US Department of Commerce; Centers for Medicare & Medicaid Services
5
WHY SHOULD
HEALTHISSUES
STOP ME FROM
LIVING MY
LIFE?
Patients now expect technology will help
them live a happy, fulfilled, ‘normal’ life,
despite their medical issues.
50% of millennials seek out care at on the go
retail locations.
HEALTHCARECONSUMERIZATION
Copyright © 2018 Accenture. All rights reserved.
Digital therapeutics are starting
to achieve outcomes comparable to
classical treatments—and they
aren’t just complementary to the
therapeutic—they are the therapeutic.
IT’SABRAVE
NEWWORLD
Copyright © 2018 Accenture. All rights reserved. 6
NEWSCIENCELANDSCAPE
This is paving the way to new science, new
markets and new business models.
Mapping the human genome enabled
breakthroughs in personalized
treatments where investment and
efficacy can be more certain.
Specialized medicines expected to
contribute to 52% of top 100 product
sales by 2024.*
Genomics expected to generate more
data than YouTube and other sources
by 2025.**
THISTIME
IT’SPERSONAL
Copyright © 2018 Accenture. All rights reserved. 7
NEWSCIENCELANDSCAPE
*Source EvaluatePharma World Preview 2017
**Source: Stephens, Zachary D., “Big Data: Astronical or Genomical;” PLoS Biology, 2015
8
NEWTECH,
NEWWORLD
AI, IoT, cloud and wearables allow
for real-time data and insight. This creates
opportunities for entirely new business
models and “always” on patient care.
Copyright © 2018 Accenture. All rights reserved.
9
…WITHDATA
INTHE
DRIVINGSEAT
Copyright © 2018 Accenture. All rights reserved.
Life sciences companies need to
grapple with big data sets
produced by many sources
including payers, health providers,
devices, and a host of other third
party data sources.
Copyright © 2018 Accenture. All rights reserved. 10
PERVASIVE
SENSORS/IoT
Health monitoring at point of need
Smart tattoos | Connected
clothing Digestible sensors
DATA
Genomic | EMR | Behavioral |
Lifestyle Nutritional
FASTER, CHEAPER,
CONNECTED
COMPUTING POWER
Private and Public Cloud | Limitless
data storage Quantum Computing
BLOCKCHAIN
Secure EMR | Digital clinical
trials Supply chain integrity/anti
counterfeiting | Patient services
ARTIFICIAL
INTELLIGENCE
RPA/Machine learning | Algorithms
Bots | Chatbots
AUTOMATED
DELIVERY/DRONES
Drones | Uber services
Autonomous vehicles
PERSONALIZED
SCIENCE
Genomic technologies | CRISPR
CarT | Nanobots | Digital pills
3D PRINTING/
MANUFACTURING IoT
Bioprinting - bones, tissues | Devices |
Proactive maintenance in manufacturing |
Lights-out factories | Connected,
responsive supply chains
LIVING
SERVICES
ANALYTICS
Prescriptive | Predictive | Cognitive
Visualization
THEPOWEROFDATAANDAI
CONVERGINGAROUNDTHEPATIENT
THETIMETO
EMBRACE
CHANGE
ISNOW.
FAST-CHANGING
COMPETITIVE
LANDSCAPE
The life sciences landscape
is getting fiercely competitive.
New players and digital entrants are
muscling in while incumbents are
repositioning to stay competitive.
Everyone wants a bigger share of the
healthcare value chain—with many
intent on fundamentally changing it.
Copyright © 2018 Accenture. All rights reserved. 12
DECEMBER
2017
JANUARY
2018
FEBRUARY
2018
MARCH
2018
APRIL
2018
+
+
+
+
+
+
+
+
+
+
JUNE
2018
+
+
Copyright © 2018 Accenture. All rights reserved. 13
WHOSEBETTINGON
NON-MOLECULARMEDICINE?
Copyright © 2018 Accenture. All rights reserved. 14
Six Example Deals & Relative Company Investment in Digital, Data and Genomics, Private
and Public funding Transactions 2007 — 2017 (Accenture Research Infographic)
DIGITAL DATA
GENOMICS
Biogen
95K – $400M
Sanofi Ventures – $400M
Otsuka – Collaboration
Harbin Gloria – $40M (JV) 2016
Many more
Roche
Sanofi Ventures
UCB
Amgen Ventures
Lilly
Novartis
Gementtry
Novo – $9M 2017
Pfizer – $9M 2017
JNJ
BMS
Celgene
Merck (MSD)
(Others as well non-pharma)
GRAIL
$900M
(Series B)
FLATIRON
$1.9B
Acquisition
AMRA MEDICAL
PROTEUS DIGITAL
HEALTH
VERILY
SCIENCE 37
*Source: Accenture Research, CBInsights, and Rock Health 2017 Investment Data
The opportunity to create
new value is up for grabs.
In the US, applying digital
to just six therapeutic areas
could deliver an economic
impact of $96B+.
THE
OPPORTUNITY
TORELEASE
TRAPPED
VALUE
Copyright © 2018 Accenture. All rights reserved. 15
$96.9B
potential
$60B+ risk adjusted potential*
$24B
Congestive
Heart Failure
6,325,226
US patients
$13.6B risk adjusted
$42B
Diabetes
38,260,665
US patients
$30.3B risk adjusted
$10B
Alzheimer’s
Disease
5,400,000
US patients
$6.2B risk adjusted
$9.7B
HIV
1,329,913
US patients
$4.8B risk adjusted
$7.5B
Breast Cancer
3,369,487
US patients
$2.8B risk adjusted
$4.7B
Multiple
Myeloma
148,728
US patients
$2.3B risk adjusted
*Source: “Digital Affectability: Therapeutic Lens on Value;” Accenture Research, 2017
WHOWILLYOUBEIN
THENEW?
ANDHOWWILL
YOUGETTHERE?
Copyright © 2018 Accenture. All rights reserved. 17
Patient
Do patients
love the
experience?
Paying entity
Do you drive value
for the payor and
whole system?
Health &
Wellness System
Do you drive value
by connecting all
pieces?
Enhanced
Product
Outcome
Focused
Platform
EconomyData
Platforms
Intelligence/AI
Tech
Digital Basics
Data
Platforms
CHOOSEYOURPATHTO
NEWMODELS
Science
Does the science
drive breakthrough
results?
Product
ROTATETO
THENEW
Copyright © 2018 Accenture. All rights reserved. 18
1. The timing, scale and direction
of investment are crucial –
transformation will be ongoing and
paced.
2. Traditional products will coexist with
specialized, digitally-enabled
science and services demanding a
modernized acquisition & growth
strategy.
3. The Wise Pivot is vital to protect your
core business while building new
outcomes-driven models where
the right partnerships are crucial.
Reimagine your core business to create new efficiencies
and unlock trapped value.
TRANSFORMYOURCORE
Copyright © 2018 Accenture. All rights reserved. 19Copyright © 2018 Accenture. All rights reserved. 19Copyright © 2018 Accenture. All rights reserved. 19
BECOME THE
MODERN
ENTERPRISE
Apply automation,
robotics, machine
learning and analytics
to accelerate and
improve R&D,
manufacturing
/supply, and access to
markets.
ACHIEVE
COMPETITIVE
AGILITY
Clarify value and
simplify systems.
Acquire and release
value to the core while
redefining your current
position in the
healthcare landscape.
EMBRACE
NEW IT
Adopt new tech and
analytics to make
better business
decisions that improve
patient care. Leverage
insights to enhance
your go-to-market
models.
TRANSFORM
FUNCTIONS
Consolidate and
strengthen your
therapeutic position,
while enabling cross-
functional scale and
connectivity via data,
digitization and your
portfolio strategy.
Invest in products and capabilities to create new value, using core strengths
to improve your competitive position and power better, faster innovations.
GROWYOURCORE
Copyright © 2018 Accenture. All rights reserved. 20Copyright © 2018 Accenture. All rights reserved. 20
USE APPLIED
INTELLIGENCE
Relentlessly pursue
value creation by
using new data-
driven insights and
analytics to inform
better, more timely,
streamlined
decisions.
BECOME A TRULY
LIVING BUSINESS
Create dominant
positions in select
therapies and/or
segments. Redefine
the new normal
patient and
customer drivers
and evolve to a
flexible personalized
service design.
EMBRACE
INDUSTRY X.0
Capitalize on the
digital reinvention of
industry via smart,
connected, ‘living’
tech to transform
your business and
accelerate
innovation.
SHAPE YOUR
FUTURE
WORKPLACE
Transform your
capabilities with
new talent, skills
and expertise to
enable a more
liquid, responsive
and innovative
future workforce.
Construct patient-centered, digitally enabled ecosystems, reaching new
markets via collaboration with traditional and non-healthcare players.
Copyright © 2018 Accenture. All rights reserved. 21
SCALEINTHENEW
ENHANCE
PRODUCTS
Apply intelligence
and services to the
scientific and
therapeutic model
across your value
chain to attract new
customers and
compete with new
entrants.
FOCUS ON
OUTCOMES
Reposition offerings
as outcomes-driven
programs. Compete
on portfolio vs
product metrics.
Share in value with
customers across
care pathways and
ecosystems.
LEVERAGE THE
PLATFORM ECONOMY
Drive value, grow
revenue, and build
competitive advantage
via new platform
offerings that scale and
cater to multiple
customers
simultaneously with a
system-lead strategy.
PATIENT
INSPIRED.
OUTCOMES
DRIVEN.
accenture.com/lifesciences

Pivot to the Patient

  • 1.
    Patient Inspired. OutcomesDriven. PIVOTTO THEPATIENT
  • 2.
    Successive waves ofdisruption are reshaping healthcare – at pace and magnitude. RIDINGWAVES OFDISRUPTION Copyright © 2018 Accenture. All rights reserved. 2 In response to converging forces, life sciences is evol ving rapidly from selling products at volume to delivering value through better patient outcomes. For those ready to seize the opportunity, it’s creating infinite new possibilities to reinvent the patient experience and redefine the future of healthcare.
  • 3.
    FORCESOFCHANGE INTODAY’S BUSINESSMODELS Copyright ©2018 Accenture. All rights reserved. 3 Socio-economic Trends + Healthcare Consumerization + New Science Landscape Catalyzed by Technology, Digital & Data
  • 4.
    Rise in healthcareoutstripped rise in GDP by 55% in 2017 in US.* Payors are demanding proof of improved patient outcomes—value-based contracts have nearly tripled since 2006. THEECONOMICS DON’TLINEUP Copyright © 2018 Accenture. All rights reserved. 4 SOCIO-ECONOMICTRENDS *Source: US Department of Commerce; Centers for Medicare & Medicaid Services
  • 5.
    5 WHY SHOULD HEALTHISSUES STOP MEFROM LIVING MY LIFE? Patients now expect technology will help them live a happy, fulfilled, ‘normal’ life, despite their medical issues. 50% of millennials seek out care at on the go retail locations. HEALTHCARECONSUMERIZATION Copyright © 2018 Accenture. All rights reserved.
  • 6.
    Digital therapeutics arestarting to achieve outcomes comparable to classical treatments—and they aren’t just complementary to the therapeutic—they are the therapeutic. IT’SABRAVE NEWWORLD Copyright © 2018 Accenture. All rights reserved. 6 NEWSCIENCELANDSCAPE This is paving the way to new science, new markets and new business models.
  • 7.
    Mapping the humangenome enabled breakthroughs in personalized treatments where investment and efficacy can be more certain. Specialized medicines expected to contribute to 52% of top 100 product sales by 2024.* Genomics expected to generate more data than YouTube and other sources by 2025.** THISTIME IT’SPERSONAL Copyright © 2018 Accenture. All rights reserved. 7 NEWSCIENCELANDSCAPE *Source EvaluatePharma World Preview 2017 **Source: Stephens, Zachary D., “Big Data: Astronical or Genomical;” PLoS Biology, 2015
  • 8.
    8 NEWTECH, NEWWORLD AI, IoT, cloudand wearables allow for real-time data and insight. This creates opportunities for entirely new business models and “always” on patient care. Copyright © 2018 Accenture. All rights reserved.
  • 9.
    9 …WITHDATA INTHE DRIVINGSEAT Copyright © 2018Accenture. All rights reserved. Life sciences companies need to grapple with big data sets produced by many sources including payers, health providers, devices, and a host of other third party data sources.
  • 10.
    Copyright © 2018Accenture. All rights reserved. 10 PERVASIVE SENSORS/IoT Health monitoring at point of need Smart tattoos | Connected clothing Digestible sensors DATA Genomic | EMR | Behavioral | Lifestyle Nutritional FASTER, CHEAPER, CONNECTED COMPUTING POWER Private and Public Cloud | Limitless data storage Quantum Computing BLOCKCHAIN Secure EMR | Digital clinical trials Supply chain integrity/anti counterfeiting | Patient services ARTIFICIAL INTELLIGENCE RPA/Machine learning | Algorithms Bots | Chatbots AUTOMATED DELIVERY/DRONES Drones | Uber services Autonomous vehicles PERSONALIZED SCIENCE Genomic technologies | CRISPR CarT | Nanobots | Digital pills 3D PRINTING/ MANUFACTURING IoT Bioprinting - bones, tissues | Devices | Proactive maintenance in manufacturing | Lights-out factories | Connected, responsive supply chains LIVING SERVICES ANALYTICS Prescriptive | Predictive | Cognitive Visualization THEPOWEROFDATAANDAI CONVERGINGAROUNDTHEPATIENT
  • 11.
  • 12.
    FAST-CHANGING COMPETITIVE LANDSCAPE The life scienceslandscape is getting fiercely competitive. New players and digital entrants are muscling in while incumbents are repositioning to stay competitive. Everyone wants a bigger share of the healthcare value chain—with many intent on fundamentally changing it. Copyright © 2018 Accenture. All rights reserved. 12 DECEMBER 2017 JANUARY 2018 FEBRUARY 2018 MARCH 2018 APRIL 2018 + + + + + + + + + + JUNE 2018 + +
  • 13.
    Copyright © 2018Accenture. All rights reserved. 13
  • 14.
    WHOSEBETTINGON NON-MOLECULARMEDICINE? Copyright © 2018Accenture. All rights reserved. 14 Six Example Deals & Relative Company Investment in Digital, Data and Genomics, Private and Public funding Transactions 2007 — 2017 (Accenture Research Infographic) DIGITAL DATA GENOMICS Biogen 95K – $400M Sanofi Ventures – $400M Otsuka – Collaboration Harbin Gloria – $40M (JV) 2016 Many more Roche Sanofi Ventures UCB Amgen Ventures Lilly Novartis Gementtry Novo – $9M 2017 Pfizer – $9M 2017 JNJ BMS Celgene Merck (MSD) (Others as well non-pharma) GRAIL $900M (Series B) FLATIRON $1.9B Acquisition AMRA MEDICAL PROTEUS DIGITAL HEALTH VERILY SCIENCE 37 *Source: Accenture Research, CBInsights, and Rock Health 2017 Investment Data
  • 15.
    The opportunity tocreate new value is up for grabs. In the US, applying digital to just six therapeutic areas could deliver an economic impact of $96B+. THE OPPORTUNITY TORELEASE TRAPPED VALUE Copyright © 2018 Accenture. All rights reserved. 15 $96.9B potential $60B+ risk adjusted potential* $24B Congestive Heart Failure 6,325,226 US patients $13.6B risk adjusted $42B Diabetes 38,260,665 US patients $30.3B risk adjusted $10B Alzheimer’s Disease 5,400,000 US patients $6.2B risk adjusted $9.7B HIV 1,329,913 US patients $4.8B risk adjusted $7.5B Breast Cancer 3,369,487 US patients $2.8B risk adjusted $4.7B Multiple Myeloma 148,728 US patients $2.3B risk adjusted *Source: “Digital Affectability: Therapeutic Lens on Value;” Accenture Research, 2017
  • 16.
  • 17.
    Copyright © 2018Accenture. All rights reserved. 17 Patient Do patients love the experience? Paying entity Do you drive value for the payor and whole system? Health & Wellness System Do you drive value by connecting all pieces? Enhanced Product Outcome Focused Platform EconomyData Platforms Intelligence/AI Tech Digital Basics Data Platforms CHOOSEYOURPATHTO NEWMODELS Science Does the science drive breakthrough results? Product
  • 18.
    ROTATETO THENEW Copyright © 2018Accenture. All rights reserved. 18 1. The timing, scale and direction of investment are crucial – transformation will be ongoing and paced. 2. Traditional products will coexist with specialized, digitally-enabled science and services demanding a modernized acquisition & growth strategy. 3. The Wise Pivot is vital to protect your core business while building new outcomes-driven models where the right partnerships are crucial.
  • 19.
    Reimagine your corebusiness to create new efficiencies and unlock trapped value. TRANSFORMYOURCORE Copyright © 2018 Accenture. All rights reserved. 19Copyright © 2018 Accenture. All rights reserved. 19Copyright © 2018 Accenture. All rights reserved. 19 BECOME THE MODERN ENTERPRISE Apply automation, robotics, machine learning and analytics to accelerate and improve R&D, manufacturing /supply, and access to markets. ACHIEVE COMPETITIVE AGILITY Clarify value and simplify systems. Acquire and release value to the core while redefining your current position in the healthcare landscape. EMBRACE NEW IT Adopt new tech and analytics to make better business decisions that improve patient care. Leverage insights to enhance your go-to-market models. TRANSFORM FUNCTIONS Consolidate and strengthen your therapeutic position, while enabling cross- functional scale and connectivity via data, digitization and your portfolio strategy.
  • 20.
    Invest in productsand capabilities to create new value, using core strengths to improve your competitive position and power better, faster innovations. GROWYOURCORE Copyright © 2018 Accenture. All rights reserved. 20Copyright © 2018 Accenture. All rights reserved. 20 USE APPLIED INTELLIGENCE Relentlessly pursue value creation by using new data- driven insights and analytics to inform better, more timely, streamlined decisions. BECOME A TRULY LIVING BUSINESS Create dominant positions in select therapies and/or segments. Redefine the new normal patient and customer drivers and evolve to a flexible personalized service design. EMBRACE INDUSTRY X.0 Capitalize on the digital reinvention of industry via smart, connected, ‘living’ tech to transform your business and accelerate innovation. SHAPE YOUR FUTURE WORKPLACE Transform your capabilities with new talent, skills and expertise to enable a more liquid, responsive and innovative future workforce.
  • 21.
    Construct patient-centered, digitallyenabled ecosystems, reaching new markets via collaboration with traditional and non-healthcare players. Copyright © 2018 Accenture. All rights reserved. 21 SCALEINTHENEW ENHANCE PRODUCTS Apply intelligence and services to the scientific and therapeutic model across your value chain to attract new customers and compete with new entrants. FOCUS ON OUTCOMES Reposition offerings as outcomes-driven programs. Compete on portfolio vs product metrics. Share in value with customers across care pathways and ecosystems. LEVERAGE THE PLATFORM ECONOMY Drive value, grow revenue, and build competitive advantage via new platform offerings that scale and cater to multiple customers simultaneously with a system-lead strategy.
  • 22.