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Herpes simplex virus (HSV) encephalitis
Clinical
findings
• Fever
• Headache
• Seizure
• Altered mental status (eg, confusion, agitation)
• ± Focal neurologic findings (eg, hemiparesis,
cranial nerve palsies, ataxia)
Diagnostic
findings
• CSF analysis:
• ↑ WBCs (↑ lymphocytes), ↑ RBCs
• ↑ Protein, normal glucose
• HSV DNA on PCR
• Brain MRI: temporal lobe hemorrhage/edema
Treatment • Intravenous acyclovir

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Herpes simplex virus (hsv) encephalitis HY

  • 1. Herpes simplex virus (HSV) encephalitis Clinical findings • Fever • Headache • Seizure • Altered mental status (eg, confusion, agitation) • ± Focal neurologic findings (eg, hemiparesis, cranial nerve palsies, ataxia) Diagnostic findings • CSF analysis: • ↑ WBCs (↑ lymphocytes), ↑ RBCs • ↑ Protein, normal glucose • HSV DNA on PCR • Brain MRI: temporal lobe hemorrhage/edema Treatment • Intravenous acyclovir