This document discusses transformerless photovoltaic grid-tied inverters and neutral point clamped (NPC) topologies that can eliminate leakage current. It proposes two basic switching cell types, the positive NPC cell and negative NPC cell, that can be used to build various NPC topologies. A family of single-phase transformerless full-bridge NPC topologies is derived, including an existing oH5 topology and some new topologies. A novel positive-negative NPC (PN-NPC) topology is analyzed in detail and shown to have similar low leakage current as another topology but higher efficiency.