.

1. Dear Dr. LuisettoMauro,
GreetingsfromICECTLondon2020!
We wouldlike toinformyouthatthe entitle abstract“topography in cancer science” hasbeenaccepted
for Poster presentation.
Thank youBestRegards,
Lucy Andrea,
Cancer London2020 Leadership&Committees
Tel:+1-650-835-7727
cancer_cong@cancerlondonconf.com
POSTER ABSTRACT PRESENTATION CANCER2020
July6 - 8, 2020
https://www.icecancerlondon.com/#header
"International Conference andExhibitionof Cancer & Therapeutics"(ICECT 2020) invitesall the delegates
to our upcomingconference whichisgoingtobe heldinLondon,UK duringJuly6 - 8, 2020. The theme of
our conference is“CancerCurrentResearch&Treatments"whichwill provide aninternational platformfor
discussionandsharingthe advancementsinthe CancerScience researchforpresentandfuture expansions
invarioustypesof Cancer.LeadingOncologist,Healthpractitioners,educators,researchersandstudents
will presenttheirnovel researchandprovide aninsighttothe currentresearchand future expansionsin
Cancer researchconference.
TITLE : topography incancer science
AUTHOR : luisettomauro appliedpharmacologist,IMA ACADEMY natural science branchitaly29121
KEYWORDS; cancer, oncology,topography , statistics,epidemiologypathology,stokastic events
Phenotypicexpression,undifferentiated process
INTRODUCTION
Topograhyof cancerdisease tell tothe researcheragreat source of informationuseful tobetter
understandthe pathogeneticprocessand riskfactors.
What it meanwhenina single apparatusrelatedthe topographythereare differentkindof cancer?
The probabilitynotisthe same ? whatlocal factorscan act inthissituations?

2. Why braincancer inexample startinan emispherepreferentially?Andthe same lungcancer?
Topographyinthe example of lef orrightside of coloncancer tell thatdifferentpathologicmovens
Acts in differentpart of an apparatusor organ.
The same observingthe gradientof some pathologic–toxicconditionispossible to correlate toaspecific
Condition.
Figure n1 braincancer
Figure n 2 lung cancer

3. Fig. 3 colon cancer
MATERIAL AND METHODS
Withan observational approach some relevantliterature for the scope of this work are analizedin order
to produce a global conclusion.
RESULTS DISCUSSION CONCLUSION
Relatedthe reference reportedinthisworkispossible toverifythat:
Epidemiologyof cancerisclearand the same some geographicdistributionof casesandrelationschip
Withsome local esogenousfactorsthatchange inexample Indifferentpartof the world.
The same distributionof some cancerinthe same apparatus that presentthe same phenotypic.Genotypic
fieldisareal fact evenif exposedtothe same toxicfactor.( whylungcancerstart in a lobe andnot inthe
same time inthe otherif causedbycanerogeneticsubstantia’?)
What isthe role playedbya CONGESTIVEor Hypoxicor other local factors that provide accumulationof
catabolic- immune products andresponces whitphenotypicnew expression ?

4. Many pathologicmovesprovidessignalingtogene expression ,andispossible toobserve thisphenomena
inlocal place. ( equal genoma inthe same organ or apparatusbut differentphenotypicexpressioninapart
of thissame organ or tissue insimilartoxicenvironment)
Thisare onlystokasticevent?Orcausedonlybyexogenoustoxicfactors?
Is a reaction towardslocal pathologic- toxiclocal environment?
Is the same statisticsof cancer presentationinchractheristictopographyandepidemiologythatmake
possible to thinktothishypotesys.
The same probabilityinexpositiontoa toxicmovens inthe same organnot produce cancer inall cellsof the
organ butfirstin a determinate local place.
Endogenustoxicologyandcancer topographyinanatomicscience make possibletobetterverifythe
relationshipbetweenkradients,kinetics,pathogenesis andlocal time related toxiccondition.
Stokasticeventcanexplainall kindof cancer or are involvedalsolocal time relatedpathologic- toxicologic
movens?( esogenusoralsoendogenus?)
A multidisciplinaryapproach (statistics,epidemiology,organtopography,local conditions,lifestyle factors
Gradientsof some factors, time of exposition, andthe kineticsof the presentationof some kindof cancer
inthe same organ are the rightinstrumentforsetthe pathogenesisof the cancerdisease makingpossible
to control Alsoendogenouspathological toxicological movenstimerelated.
In coloncancer isclearthe factorplayedbykindof dietinadvancedornot advance countries,innorth or
southof worldandthismust be take in greatconsiderationtointroduce new “depurative methods”to
reduce expositionof thiskindof toxicproducts.
Topographyof organ and apparatus, role playedbycongestive circle, proximitytootheranatomic
structure and relatedinflux mustalsotobe considered toexplainsome statisticaldifference in
presentationof cancerinthe same organ – apparatus as reportedinthe literature reportedinthiswork.
Conflictof interest:no
Clarification:
thisposterpresentationisproducedwithoutanydiagnosticortherapeuticintentonlytoproduce new
researchhypotesys ( isproducedunderatoxicological –pharmacological point of wiew)

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