Giardia lamblia presentation seminar to giardia lamlblia in iraq/kurdistan / erbil. MLT department to polytechnic university

1. LAMBLIA
Prepared by:
1- Jehad Yaqoob
2-Omer Ali
3-Sarkar Sardar

2. TABLE OF CONTENTS
 Introduction
 Epidemiology
 Pathogenesis
 Life cycle
 Signs & symptoms
 Diagnosis
 Transmission
 Who is at Risk?
 Treatment
 Prevention

3. INTRODUCTION
 Giardia Lamblia
 Morphology
 History and distribution

4. INTRODUCTION

5. EPIDEMIOLOGY

6. PATHOGENESIS

7. PATHOGENESIS

10. SIGNS AND SYMPTOMS
 Watery diarrhea
 Abdominal cramp
 Weight loss
 Vomiting
 Enteropathy in Chronic giardiasis
 Steatorrhea ...etc.

12. DIAGNOSIS
 Direct or indirect microscopical stool
examination
 Immunofluoroscent for antigens
 ELISA for antigens or antibodies
 PCR
 Histological section for enteropathy

14. TRANSMISSION
 Ingestion of contaminated food and water
 Person-to-person contact
 homosexually transported

15. WHO IS AT RISK?
 Children
 People without access to safe
drinking water.
 Homosex

17. TREATMENT
 Metronidazole
 Tinidazole
 Furuzolidone and nitazoxamide
are preferred in children.
 Parmomycin, for symptomatic pregnant
females.

19. PREVENTION
 Wash your hands
 Purify wilderness water
 Keep your mouth closed
 Use bottled or boiled water
 Avoid homosex

20. KEY POINTS
 Giardia is the only protozoan parasite found in the lumen of the
 human small intestine (duodenum and jejunum).
 Trophozoites are pearshaped bilaterally symmetrical
with 2 nuclei, 4 pairs of fl agella, and a ventral concave sucking disc.
They exhibit motility resembling a ‘falling leaf’.
Ellipsoid cysts contain 4 nuclei with remnants of flagella.
 Infective form: Ellipsoid cysts.
 Clinical features: Mostly asymptomatic but in some
 cases may cause diarrhea, dull epigastric pain, and malabsorption.
Stool contains excess mucus but no blood.
 Diagnosis: By microscopic demonstration of trophozoites
 or cysts in stool, enterotest, and serodiagnosis by
ELISA (ProSpec T/Giardia antigen assay).
 Treatment: Metronidazole and tinidazole are the
drugs of choice.