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Limbic System
Preview
• Limbic System
• Anatomy
• Connections
• Functions
LimbicSystem
•Theword“limbic”means“border.”
PartsofLimbicSystem
HYPOTHALAMUS
SEPTUM,
THE PARAOLFACTORY AREA
THE ANTERIOR NUCLEUS OF THE THALAMUS
PORTIONS OF THE BASAL GANGLIA
THE HIPPOCAMPUS
THE AMYGDALA
Limbic Structures & Key Functions
1. PAG Coordinated behaviors; Autonomic/Skeletal
2. Hypothalamus/HPAAxis Autonomic/hormonal control
3. Amygdala Simple significance codes/valences; mostly fear
4. Anterior cingulate (ACC) & Insula
Store Emotional/Valenced information
Recode amygdala
5. Midcingulate cortex (MCC)
Predict outcomes & Resolve ambiguity
Select outputs; mental or movement decisions
Devise new behaviors for new problems
6a. Dorsal Raphe Nucleus (DRN) Regulate mood
6b. Locus coeruleus (LC) Coordinate responses to events & Enhance valenced
memories
7. Autonomic Nerv Sys (ANS) Supports skeletomotor output & Enhances CNS
memory of valenced objects/events
“REWARD” AND “PUNISHMENT” FUNCTION OF THE LIMBIC SYSTEM
affective
• pleasant or unpleasant
• reward or punishment, or satisfaction or aversion
Reward & Punishment
• Major reward centers
• Along the course of the medial
forebrain bundle, especially in
the lateral and ventromedial
nuclei of the hypothalamus.
• Punishment
• Central gray area surrounding
the aqueduct of Sylvius in the
mesencephalon and extending
upward into the periventricular
zones of the hypothalamus and
thalamus
Rage when punishment activated
• (1) develop a defense posture,
• (2) extend its claws,
• (3) lift its tail,
• (4) hiss,
• (5) spit,
• (6) growl
• (7) develop piloerection, wide-open eyes, and dilated pupils.
Habituation
Form of learning in which an organism decreases or
ceases its responses to a stimulus after repeated or
prolonged presentations.
Functions of the Hippocampus
•Learning
•Lesions cause
Anterograde
Amnesia
•Consolidation of
memory
Functions of the
Amygdala
Effects of Stimulating the Amygdala.
(1) increases or decreases in arterial pressure,
(2) increases or decreases in heart rate,
(3) increases or decreases in gastrointestinal motility and secretion
(4) defecation or micturition,
(5) pupillary dilation or, rarely, constriction,
(6) pilo-erection, and
(7) secretion of various anterior pituitary hormones, especially the
gonadotropins and adrenocorticotropic hormone.
The Klüver-
Bucy
Syndrome
• Damage to
Amygdala
• Not Afraid of
anything
• Curious
• Forgets
• Hypersexual
Summary
SO why the flowers?
Limbic system

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Limbic system

  • 2. • Limbic System • Anatomy • Connections • Functions
  • 4. PartsofLimbicSystem HYPOTHALAMUS SEPTUM, THE PARAOLFACTORY AREA THE ANTERIOR NUCLEUS OF THE THALAMUS PORTIONS OF THE BASAL GANGLIA THE HIPPOCAMPUS THE AMYGDALA
  • 5.
  • 6. Limbic Structures & Key Functions 1. PAG Coordinated behaviors; Autonomic/Skeletal 2. Hypothalamus/HPAAxis Autonomic/hormonal control 3. Amygdala Simple significance codes/valences; mostly fear 4. Anterior cingulate (ACC) & Insula Store Emotional/Valenced information Recode amygdala 5. Midcingulate cortex (MCC) Predict outcomes & Resolve ambiguity Select outputs; mental or movement decisions Devise new behaviors for new problems 6a. Dorsal Raphe Nucleus (DRN) Regulate mood 6b. Locus coeruleus (LC) Coordinate responses to events & Enhance valenced memories 7. Autonomic Nerv Sys (ANS) Supports skeletomotor output & Enhances CNS memory of valenced objects/events
  • 7. “REWARD” AND “PUNISHMENT” FUNCTION OF THE LIMBIC SYSTEM affective • pleasant or unpleasant • reward or punishment, or satisfaction or aversion
  • 8. Reward & Punishment • Major reward centers • Along the course of the medial forebrain bundle, especially in the lateral and ventromedial nuclei of the hypothalamus. • Punishment • Central gray area surrounding the aqueduct of Sylvius in the mesencephalon and extending upward into the periventricular zones of the hypothalamus and thalamus
  • 9. Rage when punishment activated • (1) develop a defense posture, • (2) extend its claws, • (3) lift its tail, • (4) hiss, • (5) spit, • (6) growl • (7) develop piloerection, wide-open eyes, and dilated pupils.
  • 10. Habituation Form of learning in which an organism decreases or ceases its responses to a stimulus after repeated or prolonged presentations.
  • 11. Functions of the Hippocampus •Learning •Lesions cause Anterograde Amnesia •Consolidation of memory
  • 12.
  • 14. Effects of Stimulating the Amygdala. (1) increases or decreases in arterial pressure, (2) increases or decreases in heart rate, (3) increases or decreases in gastrointestinal motility and secretion (4) defecation or micturition, (5) pupillary dilation or, rarely, constriction, (6) pilo-erection, and (7) secretion of various anterior pituitary hormones, especially the gonadotropins and adrenocorticotropic hormone.
  • 15. The Klüver- Bucy Syndrome • Damage to Amygdala • Not Afraid of anything • Curious • Forgets • Hypersexual
  • 17. SO why the flowers?