gives the information of chemical based hazards & its safety management. only for information purpose

1. PRESENTED BY:
Mr. Ankush P. Jadhav & Miss. Tejashree R. Kedar
M. Pharm (PQA)
Email id: jadhavbrand@gmail.com, tejashrikedar@gmail.com
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CHEMICAL BASED HAZARDS

2. CHEMICAL BASED HAZARDS
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3. CONTENTS
1. Introduction
2. Sources
3. Hazards Of Organic Solvents
4. Routes of Entry
5. Hazards Control & Prevention
6. Chemical Control Program
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4. DIFFERENCE BETWEEN HAZARD AND RISK:
Hazard
Situation and things that has potential to harm a person
Risk
Possibility that harm Might occur ( injury, death ) when exposed to a hazard in
workplace
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5. DEFINITION
Any chemical, in either gas, liquid or solid form, that has the potential to
cause harm is referred as Chemical Hazard.
The Amount Of the chemical may determine whether it is a hazard or not.
Some may require exposure periods to have a toxic effect.
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6. SOURCES
Liquids such as acids, solvents especially if they do not have a label
Vapours and fumes
Flammable Liquids
Combustible Liquids
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7. HAZARDS OF ORGANIC SOLVENT
1} Environmental Effect
leakages of solvents cause significant air, land and water pollution. Fuel spills
that infiltrate the ground can cause significant contamination of drinking water
sources. For example, one litre of kerosene can contaminate 100 million
litres of drinking water ; due to their toxic nature, irritant and carcinogenic
properties they often land up as the contributory cause to many health issues such as
headaches, nausea. 7

8. They are highly flammable and require special handling and storage to avoid
combustion. The characteristics of organic solvents determine the type of hazards
present.
A majority of organic solvents are volatile. The greater the volatility of a solvent
the greater the vapour concentration in the air. Hence, inhalational exposure is an
important exposure pathway to be considered when assessing the health hazards of
the solvents.
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9. 2} Health Effect
Carcinogens
Irritants
Reproductive System
Sensitizers
Highly Toxic
Target Organ
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10. ROUTES OF ENTRY
Skin Contact
Eye Contact
Inhalations
Injection
Food Materials
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11. HAZARD CONTROL AND PREVENTION
The most effective chemical hazard control is prevention
Establishing an effective chemical control program in pharmaceutical industry
can reduce chemical hazards
Chemical Labels
Documentation i.e. Hazard Communication Program, material safety and data
sheet
Training & Information
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12. SUCCESSFUL CHEMICAL CONTROL PROGRAM
SHOULD INCLUDE
Train employees to follow safe handling and application procedures for
sanitation, maintenance or pesticides chemicals.
Store chemicals in designated areas away from ingredients, packaging material
or finished products
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13. Make it standard practice for staff, after maintenance, to properly clean and
remove all chemical residues from contact surfaces.
Do not use excessive grease or lubricants on equipment. Regularly re-evaluate all
procedures to ensure they effectively remove chemicals.
1) Selection of Gloves:
protection against chemical absorbed through the skin require reference to chemical
resistance chart.
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14. 2) Chemically resistance safety footwear is required.
3) Some chemical handling tasks may require eye protection this may be safety
goggle or full face protection.
4)There is wide range of personal protection equipment for respirators
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15. REFERENCE
www.google.com
Hazardous Chemicals : Safety Management & global Regulation, T.S.S.
Dikshith, CRC Press.
Y.K. Sing, Environmental Science, New Age International Pvt, Publishers,
Banglore.
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16. THANK YOU…
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