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Roll no. 43,44,45,46,47,48
1
•Biological source- Karela consists
of fresh green fruits of the plant
known as Momordica charantia.
•Botanical name – Momordica
charantia
•Family – Cucurbitaceae (
Pumpkin family)
•Synonyms – Momordica muricata,
Momordica zeylanica, Momordica
charantia var. muricata
2
3
4
COLOUR DARK GREEN
TASTE INTENSELY BITTER
APPEARANCE DISTINCT WARTY
EXTERIOR AND AN
OBLONG SHAPE OF
THE FRUIT
ODOUR CHARACTERISTIC
5
6
CHEMICAL CONSTITUENTS OF BITTER GOURD:
The leaves and fruits of bitter gourd contains charantin.
Charantin is a steroidal saponin and it has blood sugar
lowering activity.
These fruits also contain a cathartic principle known as
momordicin.
Other constituents in the drug are carbohydrates, mineral
matter, ascorbic acid, alkaloids, glucoside,saponins and
mucilage.
Reference: Kokate
7
PHYSICALAND CHEMICAL PROPERTIES OF KARELA
 Green,elongated,longitudinally grooved,ridged and warty
exterior.
 Consisting of large cotyledons and short straight radicle
Sr
no.
Physical parameters Obtained
values in
% w/w
1 Total ash 7%
2 Acid insoluble ash 0.2%
Water soluble ash 3.775%
Sulfated ash 8.14%
Alcohol soluble extractive 20.0%
Water soluble extractive 37.6%
Petroleum water soluble extractive 6.64%
Chloroform soluble extractive 5.6% 8
The main fatty acid was determined
as α-eleostearic (45.60%). The
other fatty acids were palmitic
(3.69%), stearic (28.00%), oleic
(12.45%), linoleic (8.90%),
arachidic (0.71%) and gadoleic
acids (0.65%).
9
CHEMICAL TESTS
• It contains carbohydrates, reducing sugars, saponins,
phenolics, tannins, and flavonoids.
• Molisch test- positive (carbohydrates)
• Fehling’s and Benedict's test- positive(reducing
sugar)
• Thin layer chromatography (TLC) done to study
variety of phytochemicals.
10
Karela is used in the form of extracts and health
drinks as an antidiabetic agent. (diabetes mellitus)
 Stomachic, carminative, tonic and cooling and also
used for the treatment of gout, rheumatism, and
disorders of spleen and liver.
 anthelmintic and anti-cancer properties
REF: BIREN SHAH& KOKATE
13
Substitutes
Wax gourd ( WINTER MELON)
14
REFERENCES:
•BIREN SHAH
•KOKATE
•(Int. J. of Pharm. Life Sci.) C. Reetesh , K. Washid, S. Nisha
and P. Rekha
15

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Pharmacognosy: Karela ( Bittergourd )

  • 2. •Biological source- Karela consists of fresh green fruits of the plant known as Momordica charantia. •Botanical name – Momordica charantia •Family – Cucurbitaceae ( Pumpkin family) •Synonyms – Momordica muricata, Momordica zeylanica, Momordica charantia var. muricata 2
  • 3. 3
  • 4. 4
  • 5. COLOUR DARK GREEN TASTE INTENSELY BITTER APPEARANCE DISTINCT WARTY EXTERIOR AND AN OBLONG SHAPE OF THE FRUIT ODOUR CHARACTERISTIC 5
  • 6. 6
  • 7. CHEMICAL CONSTITUENTS OF BITTER GOURD: The leaves and fruits of bitter gourd contains charantin. Charantin is a steroidal saponin and it has blood sugar lowering activity. These fruits also contain a cathartic principle known as momordicin. Other constituents in the drug are carbohydrates, mineral matter, ascorbic acid, alkaloids, glucoside,saponins and mucilage. Reference: Kokate 7
  • 8. PHYSICALAND CHEMICAL PROPERTIES OF KARELA  Green,elongated,longitudinally grooved,ridged and warty exterior.  Consisting of large cotyledons and short straight radicle Sr no. Physical parameters Obtained values in % w/w 1 Total ash 7% 2 Acid insoluble ash 0.2% Water soluble ash 3.775% Sulfated ash 8.14% Alcohol soluble extractive 20.0% Water soluble extractive 37.6% Petroleum water soluble extractive 6.64% Chloroform soluble extractive 5.6% 8
  • 9. The main fatty acid was determined as α-eleostearic (45.60%). The other fatty acids were palmitic (3.69%), stearic (28.00%), oleic (12.45%), linoleic (8.90%), arachidic (0.71%) and gadoleic acids (0.65%). 9
  • 10. CHEMICAL TESTS • It contains carbohydrates, reducing sugars, saponins, phenolics, tannins, and flavonoids. • Molisch test- positive (carbohydrates) • Fehling’s and Benedict's test- positive(reducing sugar) • Thin layer chromatography (TLC) done to study variety of phytochemicals. 10
  • 11. Karela is used in the form of extracts and health drinks as an antidiabetic agent. (diabetes mellitus)  Stomachic, carminative, tonic and cooling and also used for the treatment of gout, rheumatism, and disorders of spleen and liver.  anthelmintic and anti-cancer properties REF: BIREN SHAH& KOKATE 13
  • 12. Substitutes Wax gourd ( WINTER MELON) 14
  • 13. REFERENCES: •BIREN SHAH •KOKATE •(Int. J. of Pharm. Life Sci.) C. Reetesh , K. Washid, S. Nisha and P. Rekha 15