2. •Biological source- Karela consists
of fresh green fruits of the plant
known as Momordica charantia.
•Botanical name – Momordica
charantia
•Family – Cucurbitaceae (
Pumpkin family)
•Synonyms – Momordica muricata,
Momordica zeylanica, Momordica
charantia var. muricata
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7. CHEMICAL CONSTITUENTS OF BITTER GOURD:
The leaves and fruits of bitter gourd contains charantin.
Charantin is a steroidal saponin and it has blood sugar
lowering activity.
These fruits also contain a cathartic principle known as
momordicin.
Other constituents in the drug are carbohydrates, mineral
matter, ascorbic acid, alkaloids, glucoside,saponins and
mucilage.
Reference: Kokate
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8. PHYSICALAND CHEMICAL PROPERTIES OF KARELA
Green,elongated,longitudinally grooved,ridged and warty
exterior.
Consisting of large cotyledons and short straight radicle
Sr
no.
Physical parameters Obtained
values in
% w/w
1 Total ash 7%
2 Acid insoluble ash 0.2%
Water soluble ash 3.775%
Sulfated ash 8.14%
Alcohol soluble extractive 20.0%
Water soluble extractive 37.6%
Petroleum water soluble extractive 6.64%
Chloroform soluble extractive 5.6% 8
9. The main fatty acid was determined
as α-eleostearic (45.60%). The
other fatty acids were palmitic
(3.69%), stearic (28.00%), oleic
(12.45%), linoleic (8.90%),
arachidic (0.71%) and gadoleic
acids (0.65%).
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10. CHEMICAL TESTS
• It contains carbohydrates, reducing sugars, saponins,
phenolics, tannins, and flavonoids.
• Molisch test- positive (carbohydrates)
• Fehling’s and Benedict's test- positive(reducing
sugar)
• Thin layer chromatography (TLC) done to study
variety of phytochemicals.
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11. Karela is used in the form of extracts and health
drinks as an antidiabetic agent. (diabetes mellitus)
Stomachic, carminative, tonic and cooling and also
used for the treatment of gout, rheumatism, and
disorders of spleen and liver.
anthelmintic and anti-cancer properties
REF: BIREN SHAH& KOKATE
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