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Classification of crude drugs
DR. SIDDHI UPADHYAY
H.O.D. & ASSOCIATE PROFESSOR
DEPT. OF PHARMACOGNOSY AND PHYTOCHEMISTRY
SIGMA INSTITUTE OF PHARMACY
Classification of crude drugs
1. Alphabetical classification
2. Morphological classification
3. Taxonomical classification
4. Chemical classification
5. Pharmacological classification
6. Chemo-taxonomical classification
7. Sero-taxonomical classification
Alphabetical classification
The crude drugs are arranged according to the alphabetical
order/form of their Latin and English names. Some of the
Pharmacopoeias and reference books which classify crude
drugs according to this system are as follows.
The time-tested alphabetical classification is now-a-days
considered to be the least disputed way of classification in
all walks of life.
Pharmacopoeias have always been written on this basic
mode of classification. For drugs either Latin names or
common vernacular names can be used.
1)Indian Pharmacopoeia (IP) 1955(Latin)
2)Indian Pharmacopoeia (IP) 1966(English)
3)British Pharmacopoeia (BP) (English)
4)British Pharmacopoeia Codex(BPC) (English)
5)United Statesof Pharmacopoeia (USP) (English)
6)European Pharmacopoeia (Latin)
Advantages:
It is simple method, in this system location,
tracing and addition of the drug is easy,
No technical person is required for handling the system.
Disadvantages:
Scientific nature of the
by this method,
drug cannot be identified
whether they are organised or
unorganised drug.
This system does not help in distinguishing the drugs of
animal and mineral source. (Original source is not clear)
plant,
• Examples:
• Acacia, Agar, Benzoin, Beeswax, Cinchona,
Cinnamon, Digitalis, Datura, Ephedra, Jalap,
Kino, Linseed,
Fennel,
Mustard,Ginger, Isapagol,
Nutmeg, etc.
Morphological classification
• Here the crude drugs are arranged (Grouped)
according to the plant or animal represented into
organised (Cellular) drugs and unorganised (
Acellular ) drugs.
•Organised (Cellular):
•Drugs are the direct parts of the plant and are
divided into leaves, barks wood, root, rhizome, seed,
fruit, flower, stem, hair and fibers.
• Unorganised ( Acellular):
• Drugs are the products of plant, animal and mineral
sourceand they are divided into dried latex, dried
juice, dried extracts, gums, resins,fixed oils and fats,
waxes,volatile oil, animal products, minerals (Solids,
liquids, semisolids etc).
Plant parts
Leaves
Barks
Wood
Roots
Rhizomes
Flowers Seeds
Fruits Stems
Hair and Fibres
Drugs
Datura, Senna, Vasaka,
Digitalis, Cinnamon,
Cinchona, Kurchi,
Quassia, Sandalwood, Red
sanders
Rauwolfia, Liquorice, Ipecac
Ginger, Podophyllum,
Turmeric Clove, Saffron,
Pyrethrum
Nux vomica, Linseed,
Isapgol Fennel, Coriander, Dill
Ephedra
Organised drugs
(Plant)
(Cellular drugs)
Plant, animal, Mineral Drugs
Dried latex Opium, Papain
Dried Juice Aloe, Kino
Dried extracts Agar, Catechu, Pectin
Gums
Resins
Acacia, Tragacanth, Stericulia
Benzoin, Colophony, Asafoetida
Fixed oils and fats Castor , Chaulmoogra, Cotton seed
Waxes Beeswax, Spermaceti
Volatile oils Coriander, Cinnamon, Clove
Animal products Bees wax, Shark liver oil, Gelatin
Minerals Bentonite, Kaolin, Talc
Unorganised drugs
(Acellular drugs)
• Advantages:
• This system of classification is more convenient for
practical study especially when the chemical nature of
the drug isnot clearlyunderstood.
• This type of classification is very useful in identifying the
adulterants used.
• Disadvantages:
• It does not give an idea about biological source,
chemical constituents and uses.
•When different parts of the plant
contain different chemical constituents, it isdifficult
to classifythem.
Taxonomical classification
•In this systemthe drug are arranged according
to taxonomical studies. The drugs are arranged
according to their phylum, order, family, genus and
species.It ispurely a type of botanical
classification or biological classification and
restricted mainly to crude drugs from plant source.
Phylum
Angiosperms
(Monocotyledons)
Order
Liliflorae
Microspermae
Family
Liliaccae
Dioscoriaceae
Drugs
Colchicum, Asparagus
Dioscorea, Vanilla
Angiosperms
(Dicotyledons)
Papaverales Papaveraceae Opium
Rosales
Rutales
Rosales
Leguminaceae
Rutaceae
Almond, Rose oil
Glycyrihiza, Senna
Bael,Lemon, Orange
Rhamnales
Malvales
Umbelliflorae
Rhamnaceae
Malvaceae
Umbelliferae
Gentianales Loganiaceae
Gentianceae
Apocyanaceae
Cascara Cotton
Coriander,Caraway,
Fennel
Nuxvomica Chirata
Kurchi, Strophanthus
• Advantages:
• Easyfor the classification of crude drugs
• Disadvantages:
• The system is criticized for its failure to recognize the
organised / unorganised nature of crude drugs in their
morphological studies.
• The system fails to face into an account chemical nature of
active constituent and therapeutic significance of crude
drugs.
• The drugs obtained from plants having alternate leaves,
flowers, seeds, capsules (Hyocyamus, Datura, Bellodonna,
Stromonium) are considered with other members of
solanaceae.
Chemical classification
•Here, the crude drugs are divided into different
groups according to the chemical nature of their
most important constituent present in the drug to
which the pharmacological/therapeutic activity of
drug isattributed.
Chemical constituents Drugs
Alkaloids
Glycosides
Tannins
Volatile oil
Lipids
Carbohydrates and derived
products
Resins
Vitamins & hormones
Proteins & enzymes
Datura, Vasaka, Vinca, Lobelia
Cascara, Senna, Digitalis
Catechu, Myrobalan, Ashoka
Clove, Eucalyptus, Cinnamon
Castor oil, Beeswax, Arachis oil
Acacia, Agar, Honey, Linseed
Tragacanth, Starch
Colophony, Benjoin,
Yeast, Shark liver oil, Insulin
Gelatin, Papain,
• Advantages :
• Chemical constituents are known,
• Medicinal usesare known
• Disadvantages :
• Drugs of different origin are grouped under similar chemical
titles.
• This type
placement
chemicals.
of classification makesno proper
of drugs containing two different types of
• Eg: Certain drugs are found to contain alkaloids and
glycosides(Cinchona), Fixed oil and volatile oil (Nutmeg) of
equal importance together and hence it is difficult to
categorize them properly
Pharmacological (Therapeutic) classification
pharmacological action (Therapeutic action) of
their chief active constituent (most important) or
therapeutic uses.
• Bitter
• Carminatives
• Emetics
• Anti-amoebic
• Bulk Laxatives
-
-
-
-
-
-
Quassia,Cinchona, Gentian
Dill, Clove, Fennel,Coriander
Ipecac
Kurchi, Ipecac Agar, Isapgol
Senna,Castor oil
• Expectorant
• Antitussive
-
-
-
Liquorice,
Vasaka
• Cardio- tonics - Digitalis, Squill, Stropanthus
• Cardiac depressant
• Antihypertensive
-
-
Cinchona, Veratrum
Rauwolfia
• Central analgesics
• CNSstimulants
• CNSdepressants
•
•
•
•
•
Antispasmodics
Anticancer
Antirheumatics
Anthelmintics
Astringents
• Antimalarials
• Local anesthetics
-
-
-
-
-
-
-
-
-
-
Opium
Coffee
Opium
Bellodonna
Vinca, Podophyllum, Cochicum
Aconite, Guggul, Colchicum
Vidang, Quassia,Malefern
Catechu.
Cinchona,Artemisia.
Coca
• Advantages
• Thespecial advantage isthat if even chemical constituents of
the crude drugs are not known they can be classified
properly on the basisof therapeutic or pharmacological uses.
• Disadvantages
• Regardless of morphology, taxonomical status or chemical
nature, the drugs are grouped together, provided they
exhibit similar pharmacological uses.
• Eg:Senna, Castor oil, Jalap, Colocynth are grouped together
as purgatives/laxatives because of their common
pharmacological action.
Chemo-taxonomical classification
• In this system of classification, the equal importance is
given for taxonomical status and chemical
constituents. There are certain types of chemical
constituents which are characteristics of certain
classes of plants.
• Eg:Tropane alkaloids generally occur in most of the
members of Solanaceae
• Eg: Volatile oils occur in the members of
Umbelliferae and Rutaceae.
• Advantages
• It gives idea about therapeutic use of plant and other
related plants of same family as their constituents are
same.
• Eg. Plants (Jalap, Ipomoea) of family Convolvulaceae
containing resins have drastic purgative action.
Sero-taxonomical classification
• In this system of classification,
application of serology is used in solving
taxonomical problems.
• Serology is the study of antigen-antibody reaction.
• Antigens are the substances that stimulate
antibody formulation.
• Antibodies are highly specific protein mulecules,
that will be increase immune system.
• These antibodies will be helpful in finding
similarities and dissimilarities of different taxa.
• Thus how, we can say that serology study is related
to study of taxonomy.
THANK YOU !!!
siupa.pharma@gmail.com

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Classification of crude drugs by chemical, morphological and pharmacological properties

  • 1. Classification of crude drugs DR. SIDDHI UPADHYAY H.O.D. & ASSOCIATE PROFESSOR DEPT. OF PHARMACOGNOSY AND PHYTOCHEMISTRY SIGMA INSTITUTE OF PHARMACY
  • 2. Classification of crude drugs 1. Alphabetical classification 2. Morphological classification 3. Taxonomical classification 4. Chemical classification 5. Pharmacological classification 6. Chemo-taxonomical classification 7. Sero-taxonomical classification
  • 4. The crude drugs are arranged according to the alphabetical order/form of their Latin and English names. Some of the Pharmacopoeias and reference books which classify crude drugs according to this system are as follows. The time-tested alphabetical classification is now-a-days considered to be the least disputed way of classification in all walks of life. Pharmacopoeias have always been written on this basic mode of classification. For drugs either Latin names or common vernacular names can be used.
  • 5. 1)Indian Pharmacopoeia (IP) 1955(Latin) 2)Indian Pharmacopoeia (IP) 1966(English) 3)British Pharmacopoeia (BP) (English) 4)British Pharmacopoeia Codex(BPC) (English) 5)United Statesof Pharmacopoeia (USP) (English) 6)European Pharmacopoeia (Latin)
  • 6. Advantages: It is simple method, in this system location, tracing and addition of the drug is easy, No technical person is required for handling the system. Disadvantages: Scientific nature of the by this method, drug cannot be identified whether they are organised or unorganised drug. This system does not help in distinguishing the drugs of animal and mineral source. (Original source is not clear) plant,
  • 7. • Examples: • Acacia, Agar, Benzoin, Beeswax, Cinchona, Cinnamon, Digitalis, Datura, Ephedra, Jalap, Kino, Linseed, Fennel, Mustard,Ginger, Isapagol, Nutmeg, etc.
  • 9. • Here the crude drugs are arranged (Grouped) according to the plant or animal represented into organised (Cellular) drugs and unorganised ( Acellular ) drugs. •Organised (Cellular): •Drugs are the direct parts of the plant and are divided into leaves, barks wood, root, rhizome, seed, fruit, flower, stem, hair and fibers.
  • 10. • Unorganised ( Acellular): • Drugs are the products of plant, animal and mineral sourceand they are divided into dried latex, dried juice, dried extracts, gums, resins,fixed oils and fats, waxes,volatile oil, animal products, minerals (Solids, liquids, semisolids etc).
  • 11. Plant parts Leaves Barks Wood Roots Rhizomes Flowers Seeds Fruits Stems Hair and Fibres Drugs Datura, Senna, Vasaka, Digitalis, Cinnamon, Cinchona, Kurchi, Quassia, Sandalwood, Red sanders Rauwolfia, Liquorice, Ipecac Ginger, Podophyllum, Turmeric Clove, Saffron, Pyrethrum Nux vomica, Linseed, Isapgol Fennel, Coriander, Dill Ephedra Organised drugs (Plant) (Cellular drugs)
  • 12. Plant, animal, Mineral Drugs Dried latex Opium, Papain Dried Juice Aloe, Kino Dried extracts Agar, Catechu, Pectin Gums Resins Acacia, Tragacanth, Stericulia Benzoin, Colophony, Asafoetida Fixed oils and fats Castor , Chaulmoogra, Cotton seed Waxes Beeswax, Spermaceti Volatile oils Coriander, Cinnamon, Clove Animal products Bees wax, Shark liver oil, Gelatin Minerals Bentonite, Kaolin, Talc Unorganised drugs (Acellular drugs)
  • 13. • Advantages: • This system of classification is more convenient for practical study especially when the chemical nature of the drug isnot clearlyunderstood. • This type of classification is very useful in identifying the adulterants used. • Disadvantages: • It does not give an idea about biological source, chemical constituents and uses. •When different parts of the plant contain different chemical constituents, it isdifficult to classifythem.
  • 15. •In this systemthe drug are arranged according to taxonomical studies. The drugs are arranged according to their phylum, order, family, genus and species.It ispurely a type of botanical classification or biological classification and restricted mainly to crude drugs from plant source.
  • 16. Phylum Angiosperms (Monocotyledons) Order Liliflorae Microspermae Family Liliaccae Dioscoriaceae Drugs Colchicum, Asparagus Dioscorea, Vanilla Angiosperms (Dicotyledons) Papaverales Papaveraceae Opium Rosales Rutales Rosales Leguminaceae Rutaceae Almond, Rose oil Glycyrihiza, Senna Bael,Lemon, Orange Rhamnales Malvales Umbelliflorae Rhamnaceae Malvaceae Umbelliferae Gentianales Loganiaceae Gentianceae Apocyanaceae Cascara Cotton Coriander,Caraway, Fennel Nuxvomica Chirata Kurchi, Strophanthus
  • 17. • Advantages: • Easyfor the classification of crude drugs • Disadvantages: • The system is criticized for its failure to recognize the organised / unorganised nature of crude drugs in their morphological studies. • The system fails to face into an account chemical nature of active constituent and therapeutic significance of crude drugs. • The drugs obtained from plants having alternate leaves, flowers, seeds, capsules (Hyocyamus, Datura, Bellodonna, Stromonium) are considered with other members of solanaceae.
  • 19. •Here, the crude drugs are divided into different groups according to the chemical nature of their most important constituent present in the drug to which the pharmacological/therapeutic activity of drug isattributed.
  • 20. Chemical constituents Drugs Alkaloids Glycosides Tannins Volatile oil Lipids Carbohydrates and derived products Resins Vitamins & hormones Proteins & enzymes Datura, Vasaka, Vinca, Lobelia Cascara, Senna, Digitalis Catechu, Myrobalan, Ashoka Clove, Eucalyptus, Cinnamon Castor oil, Beeswax, Arachis oil Acacia, Agar, Honey, Linseed Tragacanth, Starch Colophony, Benjoin, Yeast, Shark liver oil, Insulin Gelatin, Papain,
  • 21. • Advantages : • Chemical constituents are known, • Medicinal usesare known • Disadvantages : • Drugs of different origin are grouped under similar chemical titles. • This type placement chemicals. of classification makesno proper of drugs containing two different types of • Eg: Certain drugs are found to contain alkaloids and glycosides(Cinchona), Fixed oil and volatile oil (Nutmeg) of equal importance together and hence it is difficult to categorize them properly
  • 23. pharmacological action (Therapeutic action) of their chief active constituent (most important) or therapeutic uses.
  • 24. • Bitter • Carminatives • Emetics • Anti-amoebic • Bulk Laxatives - - - - - - Quassia,Cinchona, Gentian Dill, Clove, Fennel,Coriander Ipecac Kurchi, Ipecac Agar, Isapgol Senna,Castor oil • Expectorant • Antitussive - - - Liquorice, Vasaka • Cardio- tonics - Digitalis, Squill, Stropanthus
  • 25. • Cardiac depressant • Antihypertensive - - Cinchona, Veratrum Rauwolfia • Central analgesics • CNSstimulants • CNSdepressants • • • • • Antispasmodics Anticancer Antirheumatics Anthelmintics Astringents • Antimalarials • Local anesthetics - - - - - - - - - - Opium Coffee Opium Bellodonna Vinca, Podophyllum, Cochicum Aconite, Guggul, Colchicum Vidang, Quassia,Malefern Catechu. Cinchona,Artemisia. Coca
  • 26. • Advantages • Thespecial advantage isthat if even chemical constituents of the crude drugs are not known they can be classified properly on the basisof therapeutic or pharmacological uses. • Disadvantages • Regardless of morphology, taxonomical status or chemical nature, the drugs are grouped together, provided they exhibit similar pharmacological uses. • Eg:Senna, Castor oil, Jalap, Colocynth are grouped together as purgatives/laxatives because of their common pharmacological action.
  • 28. • In this system of classification, the equal importance is given for taxonomical status and chemical constituents. There are certain types of chemical constituents which are characteristics of certain classes of plants. • Eg:Tropane alkaloids generally occur in most of the members of Solanaceae • Eg: Volatile oils occur in the members of Umbelliferae and Rutaceae.
  • 29. • Advantages • It gives idea about therapeutic use of plant and other related plants of same family as their constituents are same. • Eg. Plants (Jalap, Ipomoea) of family Convolvulaceae containing resins have drastic purgative action.
  • 31. • In this system of classification, application of serology is used in solving taxonomical problems. • Serology is the study of antigen-antibody reaction. • Antigens are the substances that stimulate antibody formulation. • Antibodies are highly specific protein mulecules, that will be increase immune system. • These antibodies will be helpful in finding similarities and dissimilarities of different taxa. • Thus how, we can say that serology study is related to study of taxonomy.