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SARS-COV-2 cell entry depends on ACE2 and TMPRSS2
receptor and is blocked by clinically proven protease
inhibitor
Submitted To :-
Dr. Monika Asthana
Dr. Avnish Kumar
Dr. Bhavyata Dua
Department of Biotechnology
School of Life Sciences
Khandari Campus
DBRAU AGRA
Submitted by :-
HRIDYESH RIYAR
M.sc Biotechnology
4th Semester
SARS-COV-2
SARS-COV-2 is the virus strain that causes
corona virus disease 2019 (COVID-19).
Corona virus belongs to the family
coronaviridae.
Corona virus originated from WUHAN china.
WHO called this disease is corona virus disease
or simply called COVID-19.
Other name is SARS-COV-2 [severe acute
respiratory syndrome corona virus-2]
HISTORY
Biological structure of SARS-COV-2
HOW DOES IT INFECT THE CELL?
CLINICALLY APPROVED
MEDICATION
DIFFERENCE BETWEEN NORMAL LIFE CYCLE AND CLINICALLY
APPROVED MEDICATION
Goal
• The goal of the study was to obtain insights
into how SARS-COV-2 facilitates viral entry
into target cells and how this process can be
blocked.
RESULTS
DISCUSSION
SUMMARY
RESPOND SUGGESTION
CURRENT TREATMENTS
ACE2 AND TMPRSS2 RECEPTOR

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ACE2 AND TMPRSS2 RECEPTOR