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DISEASE : COVID-19
VIRUS : SARS-CoV-2
SUB-TOPICS:
Introduction
Structure of SARS-CoV-2
Types of SARS-CoV-2
Transmission of SARS-CoV-2
Viability of the virus
Symptoms of COVID- 19
Diagnosis
Treatment
Made by-
Stud-e
Medical disclaimer:
This channel does not provide medical advice. The content available on this channel do not provide
a diagnosis or other recommendation for treatment and are not a substitute for the professional
judgment of a healthcare professional in diagnosis and treatment of any person or animal. The
determination of the need for medical services and the types of healthcare to be provided to a
patient are decisions that should be made only by a physician or other licensed health care
provider. Always seek the advice of a physician or other qualified healthcare provider with any
questions you have regarding a medical condition.
 Coronavirus cause respiratory infections ranging from common cold to
severe diseases like SARS and MERS.
 SARS : Severe acute respiratory syndrome.
 MERS : Middle East respiratory syndrome.
 SARS outbreak was seen in 2002 while MERS outbreak was seen in 2012.
 COVID-19 is an infectious disease similar to SARS and caused by virus
SARS-CoV-2.
 This new disease and virus were unknown before outbreak began in
Wuhan, China in December 2019.
CHINA
 COVID-19 is a pandemic that affects people globally.
 Researches say that human coronavirus(SAR-CoV-2) is 96.2%
genetically similar to bat coronavirus(RaTG13).
STRUCTURE OF SARS-CoV-2-
SARS-CoV-2 TYPES-
S-Type L-type
• These are seen in 30% of cases. • These are seen in 70% cases.
• The infection caused by s-type virus is less
severe and less aggressive.
• Infection caused is with severe symptoms
and is more aggressive in comparison to s-
type.
• This virus is assumed to be originated with
an animal component.
• This virus is assumed to have evolved from
s-type.
The virus can be transmitted by-
 Respiratory droplets while sneezing or coughing and can be
viable for 3 hours after forming aerosolized droplets.
 The droplets can travel more than 25 feet in less than a
second.
 It can also be transmitted by fecal-oral route.
Viability of SARS-CoV-2 on different surfaces-
SURFACES VIABILITY DURATION
• Aluminum, Latex, and Copper 8 Hours
• Cardboards 24 Hours
• Counter tops, Plastics, and
• Stainless steel
1-3 Days
• Glass and Wood 5 days
SYMPTOMS-
 Fever
 Cough
 Shortness of breath
 Difficulty in breathing
 Chills
 Repeated shaking with chills
 Muscle pain
 Sore throat
 Headache
 New loss of taste or smell
 These symptoms develop due to severe lung damage which can
cause ARDS (Acute Respiratory Distress Syndrome).
 ARDS occurs when the fluid build up in and around the lungs.
This can cause Septic Shock i.e. infection causing organ failure and
dangerously low blood pressure.
ARDS and Septic Shock are mainly the cause of deaths.
 Once a person is infected the symptoms develop 5 days later.
This is known as the incubation period.
5 DAYS
 All viruses have a Ro value . Ro is the reproductive number of a virus.
 SARS-CoV-2 has a Ro has of 2.2.
Ro =1
Ro =2
DIAGNOSIS-
 RT-PCR- It can detect small amounts of viral RNA.
 Chest CT is performed in the cases of severe pulmonary
disease suspects.
 Isothermal amplification.
 Rapid serological testing.
 Also differential diagnosis should be ruled out.
TREATMENT-
 Mild symptoms- Isolation at home should be done to get rest
and fluids are prescribed.
 Severe cases- supportive care is given.
 Some data show Remdesivir (anti viral drug) which was
previously used for Ebola to be helpful.
 Other Researches-
1. Lopinavir + Ritonavir.
2. Chloroquine + Hydroxychloroquine.
3. Hydroxychloroquine + Azithromycin.
 Researchers are developing vaccines in countries around the
world and it is estimated to be developed by 2021.
STAY HOME.
STAY SAFE.
THANK YOU FOR YOUR TIME !
Please feel free to connect with me on..
 Youtube: https://www.youtube.com/channel/UCamq_hyE57q7nWbr4pAH-wg
 Instagram: https://www.instagram.com/stud_e_/
 LinkedIn: https://www.slideshare.net/ShantiGupta
 Email: stud.e0397@gmail.com

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COVID-19 || SARS-CoV-2 || STUD-E

  • 1. DISEASE : COVID-19 VIRUS : SARS-CoV-2 SUB-TOPICS: Introduction Structure of SARS-CoV-2 Types of SARS-CoV-2 Transmission of SARS-CoV-2 Viability of the virus Symptoms of COVID- 19 Diagnosis Treatment Made by- Stud-e
  • 2. Medical disclaimer: This channel does not provide medical advice. The content available on this channel do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.
  • 3.  Coronavirus cause respiratory infections ranging from common cold to severe diseases like SARS and MERS.  SARS : Severe acute respiratory syndrome.  MERS : Middle East respiratory syndrome.  SARS outbreak was seen in 2002 while MERS outbreak was seen in 2012.
  • 4.  COVID-19 is an infectious disease similar to SARS and caused by virus SARS-CoV-2.  This new disease and virus were unknown before outbreak began in Wuhan, China in December 2019. CHINA
  • 5.
  • 6.  COVID-19 is a pandemic that affects people globally.  Researches say that human coronavirus(SAR-CoV-2) is 96.2% genetically similar to bat coronavirus(RaTG13).
  • 8. SARS-CoV-2 TYPES- S-Type L-type • These are seen in 30% of cases. • These are seen in 70% cases. • The infection caused by s-type virus is less severe and less aggressive. • Infection caused is with severe symptoms and is more aggressive in comparison to s- type. • This virus is assumed to be originated with an animal component. • This virus is assumed to have evolved from s-type.
  • 9. The virus can be transmitted by-  Respiratory droplets while sneezing or coughing and can be viable for 3 hours after forming aerosolized droplets.  The droplets can travel more than 25 feet in less than a second.  It can also be transmitted by fecal-oral route.
  • 10.
  • 11. Viability of SARS-CoV-2 on different surfaces- SURFACES VIABILITY DURATION • Aluminum, Latex, and Copper 8 Hours • Cardboards 24 Hours • Counter tops, Plastics, and • Stainless steel 1-3 Days • Glass and Wood 5 days
  • 12. SYMPTOMS-  Fever  Cough  Shortness of breath  Difficulty in breathing  Chills  Repeated shaking with chills  Muscle pain  Sore throat  Headache  New loss of taste or smell
  • 13.  These symptoms develop due to severe lung damage which can cause ARDS (Acute Respiratory Distress Syndrome).  ARDS occurs when the fluid build up in and around the lungs. This can cause Septic Shock i.e. infection causing organ failure and dangerously low blood pressure. ARDS and Septic Shock are mainly the cause of deaths.
  • 14.  Once a person is infected the symptoms develop 5 days later. This is known as the incubation period. 5 DAYS
  • 15.  All viruses have a Ro value . Ro is the reproductive number of a virus.  SARS-CoV-2 has a Ro has of 2.2. Ro =1 Ro =2
  • 16. DIAGNOSIS-  RT-PCR- It can detect small amounts of viral RNA.  Chest CT is performed in the cases of severe pulmonary disease suspects.  Isothermal amplification.  Rapid serological testing.  Also differential diagnosis should be ruled out.
  • 17. TREATMENT-  Mild symptoms- Isolation at home should be done to get rest and fluids are prescribed.  Severe cases- supportive care is given.
  • 18.  Some data show Remdesivir (anti viral drug) which was previously used for Ebola to be helpful.  Other Researches- 1. Lopinavir + Ritonavir. 2. Chloroquine + Hydroxychloroquine. 3. Hydroxychloroquine + Azithromycin.  Researchers are developing vaccines in countries around the world and it is estimated to be developed by 2021.
  • 20. THANK YOU FOR YOUR TIME ! Please feel free to connect with me on..  Youtube: https://www.youtube.com/channel/UCamq_hyE57q7nWbr4pAH-wg  Instagram: https://www.instagram.com/stud_e_/  LinkedIn: https://www.slideshare.net/ShantiGupta  Email: stud.e0397@gmail.com