1. 1
OTHERS√
CALCULATIONS
55. patient use methylprednisolone iv 20mg , he want to Change to prednisolone tablet choose ?
80mg
20. Which association that define Thalidomide disaster ?
kefauver-harris amendment
131. enzyme kinetics law ?
Michaelis-Menten law
151. Cockcroft - Gault Equation is used for glomerular filtration and is indicted for?
chronic renal failure OR Bilateral renal failure & Bilateral chronic
95. Cockcroft-Gault used to calculate : ?
Stable chronic renal impaired
1. measure crcl in a case
Cockcroft- Gault
13. Equation of creatinine clearance in adult?
Cock croft
8. To estimate Cr.cl in pediatrics we use?
Schwartz equation
78. Which of the following more frequent
Mode
22. Central tendency affected by skewing values which one?
Range
28. which of these measures used in central tendency
Measures of Central Tendency: Mean, Median, and Mode
29. What is the best method to present Numerical data ?
In tables
60. PH measures:
Acidity
.pound =0.453 kg
5. 1Ib = ????
1Ib = 454 gram
17. if the mean age of participant is 50 with 5 standard deviation meaning ?
Within 5 of the age
19. GRAIN=
0.065 gram or 65mg
30. Concentration menthol in 0.6 syrup?
6
59. T 1/2 ... in first line is .... ?
0.693 k
61. If a drug is eliminated by first order elimination, what determines when will it reach steady state?
t (1/2) half life
65. drops teaspoonful
1 teaspoonful equal to 5ml
100 equal to 5ml
73. PKa for normal water in room temperature ?
14
. Drops : less than 10 mg
63) Which of the following terms measures the association between the exposure and the outcome?
Risk ratio
62- Which of the following is the ratio of the mass to the volume of object determined at a specified temperature?
relative density
STRUCTURES
33. Iso 5 particle size
no more than 3,520 par3cles equal to or larger than 0.5 microns per cubic meter of air
34. Aspirin bond ?
Covalent
635- Quinine removed group converted to antiarrythemia?
Qunidine
73- Which of the following is the precursor for 5- hydrotryptamine (serotonin)? Tryptophan
2. 2
PHYSIOLOGY
136. Which Hormones are produced by posterior pituitary gland?
Vasopressin and oxytocin
9. Normal plasma in human body in liter
35 L
16. What is function of golgi bodies?
Energy production
25. Drug stored in the body in ?
fat and protein
50. LPL is responsible for transportation of:
fats to tissue
54. If a drug has Mwt more than 500 in which way will excrete
Biliary
56. Volume of blood in the body
5 liters
63. Drug stored in the body in ?
fat and protein
66. Plasma conc. Of drug in all body is ?
rate of distribution
68. Resting membrane potential ion distribution
2Na and 3k inside while 3Na and 2k outside the inside is negative and the outside positive the resting membrane potential is -70
69. Enzyme metabolize starch ?
a-amylase
75. In which place produces spinal fluid ?
choroid plexus
84. causes of hypo thyrodism ?
iodine deficiency , low hypothalamus &pituitary hormons
85. Role of lactulose in hepatic encephalopathy ?
Decrease protein absorption - Acidifier of colon to prevent ammonia absorption- Alkylation of colon to prevent ammonia absorption
88. not from WBC ?
Reticleucyte
89. The organ is responsible for energy production in the body?
Liver
129. cushing - like syndrome is due to ?
adrenal hyperplasia
90. Cush syndrome
Hyper adrenal
94. Posterior Pituitary gland release hormone ?
Oxytocin and antidiuretic hormone
99. Reabsorption of Amino acid in renal tubules ?
proximal convolutions
100. Colon absorptive surface is important for ?
water, K
134. Amount of water in adult male ?
60%
male 60 % female about 55%
67. Normal range of Cr. clearance
Normal creatinine clearance is 88–128 mL/min for healthy women and 97–137 mL/min for healthy men
101. Normal Cr.cl ?
Creatinine clearance in a healthy young person is about 95 milliliters per minute for women/120 milliliters per minute for men. This means
that each minute, that person's kidneys clear 95-120 mL of blood free of creatinine.
102. Precursor of bile ?
Cholesterol
103. Function of GOLGI bodies in the cell ?
transporting, modifying, and packaging proteins and lipids into vesicles for delivery to targeted destinations
104. Function of mitochondria in the cell ?
Energy
106. lab test can be done now ?
Iron
3. 3
107. what lab tests have to done today: ?
CBC
108. total body clearance=
CLhepatic+ CLpulmonary +CLrenal
120. EnteroHepatic recycling depend on all of the following except ?
Extent of drug absorption from stomach
135. Hormone released from posterior gland ?
vasopressin and oxytocin
136. metabolism in intestine ?
Hydrolysis
141. hormone released from adrenal cortex Adrenocorticotropic ?
Progesterone
144. in ovulation phase, Which hormone predominate?
LH
148. Why creatinine is used as an indicator for renal function?
It's bound to protein that is only excreted by kidney
35. Role of Krebs cycle?
Energy production and biosynthesis
(8)What is the estimated amount of plasma in a 70-Kg male? (50-55ml/kg)
-3.5 liter
83- Where dose the electron transport chain reaction pathway take ?
Inner mitochondrial membrance
90-Which of the following medications would inhibit uncoating of the viral RNA?
Rimantadine
86- Which of the following enzymes is responsible for forming DNA copy from RNA?
Reverse transcriptase
24) What the function of small nuclear (snRNAs) in protein synthesis ?
Modifies mRNA molecules
37) Which of the following pairs represents the purines nitrogenous bases?
Adenine (A) and guanine (G)
6) Which of the following is an inhibitory neurotransmitter ?
B)Sertonin
D)Gama aminobutyric acid (GABA)
42) Which of the following is the process of breaking down of glycogen ?
Glycogenolysis
52) Which of the following inhibits gluconeogenesis?
A)Insulin√ B)Glucagon C)Epinephrine D)Glucocorticoids
(46) Which of following is a vasopressor that is given in a fixed dose without titration for patients with septic shock?
Vasopressin
99- Which the following hormones maintains the concentration of water in the body?
Vasopressin(antidiuretic hormone)
73- Which of the following is a non-essential amino acid?
Cysteine
N.B:-The 9 essential amino acids are: histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.
16- Which of the following describe glucose uptake and usage by as compared to other tissues of the body?
Brain cells can uptake and use glucose without being stimul insulin
60) Which of the following compounds is urea cycle a biochemical reaction that produce urea from ?
Ammonia(NH3)
24- What is the main absorptive function of the colon?
Water and glucose
D)Sodium, chloride, and water
N.B:-The role of the ascending colon is to absorb the remaining water and other key nutrients from the indigestible material,
36) Which of the following best describes the role of colipase in digestion of lipids?
It acts as co-enzyme for the action of lipase in the presence of bile acids
2) Which of following play a role in calcium homeostasis ?
1,25-dihydrocycholecalciferol and calcitonin
14-A 65-year patient suffered from Osteomalacia with finger numbness, tingling and burning of extremities. The doctor prescribed vitamin D and
an IV calcium supplement. Which of the following calcium salts did the physician most likely prescribed ?
Calciumgluconate (9%calcium)
N.B:-Ca phoshate no more effective — and may in fact be less effective — than calcium citrate or calcium carbonate.
94- A 60-year-old man presents with profound hypotension and tachycardia. He has been on nifedipine for hypertension and accidently took the
over dose of it. Which of the following is the most appropriate management?
calcium gluconate
4. 4
1)Which of the following is a common enzyme polymorphism that could potentially alter clopidogrel efficacy ?
Cyp2c19
35- Which of the following polymorphic enzyme is responsible for the conversion of codeine to morphine?
CYP2D6
(40) A patient was started on codeine 15 mg orally as needed for postoperative pain. One day after starting codeine, the patient presents to the
Emergency Department with confusion, headache and shortness of breath.
Which of the following most likely describes the patient's gentotype?
rapid metabolizer of CYP 2D6
N.B:-CYP2D6 enzyme converts codeine into its active metabolite, morphine, which provides its analgesic effect. Consequently, pain relief may be
inadequate in individuals who have 2 inactive copies of CYP2D6 (“poor metabolizers”, PMs), because of reduced morphine levels.
In contrast, individuals who have more than 2 normal-function copies of the CYP2D6 gene (“ultrarapid metabolizers”, UMs) are able to metabolize
codeine to morphine more rapidly and more completely. As a result, even with therapeutic doses of codeine, these individuals may experience the
symptoms of morphine overdose, which include extreme sleepiness, confusion, and shallow breathing,
PHARMACEUTICS
. Infusion of hypotonic solution = hemodialysis
. Infusion of hypertonic solution= shrinking of blood cells
. Surfactant not used orally: Na lauryl sulphate
. Binding plasma protein :⬆ half life
55- Which of the following is the benefit from adding a conjugate of polyethylene glycol (PEG) in some medications like Peg-interferon?
to extend the half-life of medications
147. One of the following is a component of drug processes ?
Administration
15. procss of using the drug is ?
Administration
49. Change the drug from tablet to final powder:
Disintegration
93. The most common disintergrator in compressed tablets is ?
Starch
97. Gums are used in tabletting primarily as ?
Binding agents
105. Solid dosage forms are better than Solution dosage form because ?
Accurate dose stable & Easy to handle & More
47. Obese patient what the effect of obesity on distribution of lipid soluble drug
Increase
48. Obese patient what the effect of obesity on absorption of lipid soluble drug
no effect
149. Linear pharmacokinetics ?
First order
Non - linear ? Zero order
91- The ionization of the drug is very important to understand the pharmacodynamic of the drug.Which of the following forms are absorbed from
the stomach?
non polar-unionized
2. after drug metabolism the drug become ?
Polar
110. Drug after metabolized in liver it will become ?
Polar
118. At 25 C, benzoic acid is much more soluble in benzene (C6H6) than it is in water. In this situation benzoic acid could be considered
to be ?
Non-polar
119. The following liquids are least likely to be miscible ?
non-polar + polar
3. albumin and dextran and starch are ?
colloid solutions
7. Oleaginous base for ointment?
white petroleum
18. Carbohydrate polymer ?
Glucagon
21. Which one carry high risk for IV admixture?
Preparing IV admixture from non-sterile products
155. Define maslow needs in order ?--------------
5. 5
27. Isotonic NS and Dex solution
0.9 % saline
Or 5% Dextrose
112. Which of the following is colloid solution ?
Albumin
122. Hypertonic solutions can be adjusted by ?
Make dilution by add more solvent
123. Very small molecule (1 part ) soluble in more than 10,000 part of water?
Insoluble
115. disintegration ?!
change the drug from tablet to final powder
62. Which can be problematic with iron supplements in the elderly
Absorption
31. Adsorption, which is not true ?
Chemical property and Irreversible
40. when you say on two drugs have the same bioequivalence
Pharmacokinetic parameters
79. to compare between 2 drugs use ?
Pharmacokinetic parameters effect & Pharmacodynamic parameter
54. Bioavailability refers to the extent and rate at which the active moiety (drug or metabolite) enters ?
systemic circulation ( the site of action)
132. most described dosage solid form ?
Tablet
133. Controlled released drug delivery depends on ?
Ready programmed & no influence of the body fluid
156. Which type of medication that can be crushed?
Immediate release tablet
142. liquid dosage form differ from solid in ?
ease to administation
124. The following properties are similar for both solutions and suspensions ?
The components of both solutions and suspensions can be separated from each other by physical processes & Solutions and suspensions are
composed of two or more components .
130. which is (are) electromagnetic waves??
X-ray & Gama- ray
121. Arranging the electromagnetic waves alpha,, beta,„gamma in an increase ranking in air will be ?
alpha,beta.gamma
125. All of the following to decrease the exposure to the radiation except ?
decrease the activity of radiation person
126. protect from light" in usp means ?
Amber glass
127. drugs have different crystal structures so different in ?
Polymorphism
128. suspension eye drop differ than ophthalmic solution in ?
less commonly used & used for insoluble drugs
46. method used in sterilization (autoclave was not in the choices:
dry heat
143. The method most commonly used in the sterilization in our society ?
Autoclave
96- Which of the following is the most practical method for sterilizing ophthalmic solution?
autoclaving for 15 minutes
146. All of the following to decrease exposure to radiation except?
decrease the activity of radiation person
152. DRUG Clearance means ?
The elimination of drug from the body
143. Patient take aldosterone what is factor effect in clearance?
impairment Renal
144. Max amount of individual dose we can take it intramuscular in gluteus muscle?
1ml
100- Which of the following capsules sizes has the largest size suitable for human patient?
no. 000
6. 6
57- Which of the following is the basis of the biopharmaceutics classification system of drugs?
permeability and solubility
71- Which of the following techniques will hinder tablet dissolution?
increasing tablet compression
10- Which of the following is the most common cause of drug instability?
oxldation
13- What is the usual shelf life for reconstituted and refrigerated antibiotic suspension?
7 days
Preparations
19- Which of the following is the term used to describe the pharmaceutical technique of grinding an insoluble substance to fine powder while wet?
Levigation
29- Which of the following is the main purpose of levigating a suspension during extemporaneous compounding?
reduce particte size
62-Observing evidence of instability during compounding is an important step.
Which of the following is happened should have discarded the product and not dispense it ?
Chemical potency
75- Special techniques are required during compounding of emulsion. Which of the following techniques is used for compounding of emulsion?
dry gum
46-which of the following products is an oleaginous ointment base?
Oleaginous base consists of oil+fat
ex:-
1-Soft paraffin (Petroleum)
2-Polysorb
3-Aquabase
4-Anhydrous lanolin
46-Medication order is given to the pharmacist (see table)
Olive oil 60 ml
Vitamin A 60.000 U
Water 120 ml
Sig 15 ml t.i.d
What is likely to be the final form of preparation?
An emulsion (contain oil and water)
N.B:-An emulsion is a mixture of two or more liquids that are normally immiscible
86- Which of the following is another name for a true solution?
homogeneous mixture
95- Which of the following is another term for the ability of a liquid to dissolve in another?
miscibility
1-A suspended agent is important for preparing an oral suspension. Which of the following is the characteristic of this suspending agent?
Hydrophobic, to inhibit agglomeration
N.B:- emulsifying agent is hydrophobic
1-A drug has a volume of distribution of 35L in a 70 Kg man. Which of the following best describes Its distribution?
it is dissolved in lipids
Medicines
83-Which of the following ranges of volume of distribution is deduced for warfarin (anticoagulant) that is 98% bound to proteins?
3-51
51- Which one of the following is the effect to alkaline buffers that have In commercial formutations of aspirin?
they Increase the rate of absorption by increasing the PH immediately around the disintegrating aspirin particles and accelerating their
dissolution
16- Itraconazole capsules require acidic pH optimal dissolution and absorption. Which of the following is an appropriate advice to optimize the
oral absorption of the drug?
take it with food
7. 7
PHARMACY
29) Which of the following best describes the structure of the healthcare systems in Saudi Arabia ?
3-tier system
39. A hospital on formulating drugs, Efficacy, Work overload, and Costs are taken in concern. A, B, C, D, and E are antifungal drugs
available in the market. AlI have the same efficacy. The hospital was using drug E for a period of time. According to the following data
which drug is best to be used by the hospital: DRUG COST FREQUENCY DURATION ?
2.25 BID 7 DAYS
17. What is the benefit control of infection in hospitals? To protect you and others from infection
51. Most group use OTC
Adult
4. Most source of infection in sterile area is?
People
6. scale for adverse drug reaction with drugs ?
Narnjo scale
31. causality assessment scale
Naranjo Algorithm
116. Naranjo score is 3 for propability so it is?
Naranjo score is from -4 to +13
1 to 4 possible
5 to 8 probable
9 and more definite
0 and less doubtful
12. Narnjo scale for drug = 9 what does that mean ?
Definite
145. The LABEL of drug should has?
Patient name
23. prescription label should contain ?
physician name
26. The prescription of drug should contain ?
prescriber name
24. Unit dose cassettes in hospital has doses of ?
Day
32. What is benefit of OTC ?
Easley accessible for patients
38. Which one in Intravenous IV admix is ISO CLASS 5
Cleanroom
11. in buffer room type of gloves ?
sterile gloves , with powder
76. Boric acid in preparation ?
buffer
78. Buffer system in human body ?
Bicarbonate
41. Normal water is used for which of these preparations?
External preparations
42. Aspartame is added to some preparation as
sweeting agent
43. The ability of liquid to dissolve in another liquid is called
Miscibility
44. liquid prep. differs from solid in
easy in administration
72. Abbreviation lead to drug error ?--------------------
74. about steady state concentration during IV administration ?
directly proportional to infusion rate
inversely proportional to total body clearance
80. Meaning of OMM abbreviation ?
Optimal medical management medicine
81. In parenteral nutrition what take in consideration when calculating ?
Propofol
83. How we measuring Synthetic liver function ? Albumin
8. 8
87. Example of 2 different drugs, similar letters, How we avoid errors when we inter the prescription to the system?
tall man letter
91. If drug in the marketing 2009 when expire ? ----------------
96. Intangible cost?
Pain, suffering, anxiety and fatigue
109. The latin abbreviation for(state) ?
Immediately
111. PPM mean:- ?
part per million OR million part
66- What is the Latin abbreviation for"after meals”?
P.C
79- Which of the following is the abbrevation for drug to be taken by mouth?
P.O
113. P.R.N. meaning ?
As needed
A.c: before meal
QID=QDS=4times daily
138. when FDA needs more experiments, analysis and researches about a drug in phase 4 it means ?
need more researches about safety
139. According to FDA the most dangerous abbreviation that shouldn't be written on prescription is???
Prn
140. 85 years man have pain in joint . what the most dangours abbreviation put in prescription ?
OD
153. Drugs that physician should care when using it ?
low therapeutic index
150. The following is related to dependence ?
Increasing the dose of drug associated with withdrawal symptoms if sudden decrease
47-Which of the following statements best describe drug dependence?
Discontinuation of the drug will produce withdrawl symptoms
32-what is the meaning of off-label drug use?
use of drug for unapproved indications
---------------
26) Which of the following is the function of the pharmacy and therapeutic committee in a hospital?
D)Responsible for drug formulary management
(responsible for all matters related to the use of medications in the institution, including the development and maintenance of the formulary (the
continually revised compilation of drug products available to the medical staff). The basic objectives of a P&T committee are to specify drugs of
choice and alternatives, based on safety and efficacy; to minimize therapeutic redundancies; and to maximize cost-effectiveness)
77-Which of the following committees is dedicated to developing and maintaining a list of approved medicine for the hospital medicines for the
hospital use ?
Pharmacy and therapeutics
79-Which of the following committees is responsible for requests of removing a drug from the hospital formulary?
Pharmacy and Therapeutic
59- A pharmacist is hired as in charge of controlled medication pharmacist made inventory record for controlled medications pharmacy before the
old pharmacist left. Which of the following is most likely to receive the original record?
Pharmacy
69- An ambulatory care pharmacist received a prescription for (liraglutide) (REMS), from Bariatric Endocrine consultant as per medication under
(REMS) should be provided to the patient with documents.
Which of the following is the meaning of (REMS) beside the name?
This medication is under (Risk Evaluation and Mitigation Strategy )
5) Which of the following have means that individuals have the capacity to understand basic health information to make appropriate health
decisions ?
Health literacy
27) Which of the following best describe pharmacy health literacy assessment ?
Measure how well the pharmacy is serving patients with limited health literacy skills
17) Approximately 415 million people have been diagnosis with diabetes .Which of the following terms is referred to in the mentioned statement ?
Prevalence
80- Which of the following is the appropriate defined pharmacoepidemiology?
The study of the use of and effects of drugs in large number people
84- In pharmacoeconomics and outcomes research, QALYS are used utilities. QALY is the quality-adjusted life year.
Which of the following is an interpretation of an individual with?
Perfect health
51) Which one of the following statements accurately explain the idea of ‟Diffusion of innovation therapy for health promotion?
The method of disseminating innovative ideas a through a culture
9. 9
58 )Public health is the science of protecting the health of a community Which population from the following list is their target?
Entire community
66- Which of the following is the definition of management?
The art of maximizing productivity
70) To which of the following the major histocompatibility complex unique?
Each individual
55) Which of the following situations allow for accepting verbal order?
In a code status
70- Which of the following distribution systems works better for medicine requiring a higher level of control?
Automated dispensing
44) Which of the following is used as an electronic medication dispenser to improve medication adherence ?
Med-E-Lert Automatic pill Dispenser
83-Which of the following is considered a direct method to measure adherence?
Body drug concentration
74-which of the following systems can be integrated with computerized physician order entry to guide physician during prescribing medications ?
Clinical decision support system
24-which of the following need to be considered first by a pharmacist in order to rationalise drug therapy decisions?
Pharmacotherapy workup
45) A pharmacy department needs to design a system to maximize the value of the drug therapy to the patients, Which of the following systems
should the pharmacy department operate ?
Communication with the prescriber and the therapist
91- Free medical sample drugs (formulary or non-formulary) are provided by pharmaceutical sales representatives to physicians or members of
the health care team.
Which of the following is the most appropriate recommended policy for dealing with sample drugs?
Exclude them from in-patient pharmacy, drug store or doctors' offices
100- Which following best describes the "bio- psychological approach of health"?
A)Broad view that arrtributes disease outcome to the variable interaction of biological factory psychological factors, and social factors
81-A study that investigate if drinking coffee lead to coronary hear found that there is a correlation between two variables. However drinkers are
more often smokers than the average and, correlation between drinking coffee and nicotine
consumption, strong causal correlation between smoking and the incidence of heart disease.
Which of the flowing type of bias affect this study results?
Confounding
-------------
27- Cleaning is a very important step when working with laminar flow hoods.Which of the following disinfectants is most suitable for cleaning the
hood before compounding a sterile preparation?
70% Isopropanol (isopropyl alcohol)
57- Which of the following substances is used to disinfect gloves during compounding sterile products?
70% isopropyl alcohol
99- Which of the following is the exact date for a drug to be safety taken if its expiration date December 2018?
January 1st , 2019
35- Which routes of administration result in faster absorption?
rectal
55- To ensure safe and proper disposal of hazardous waste, a color- coded system was created. Which of the following colors is the color of
hazardous waste containers?
yellow
21-Which of the following describes the best patient instruction regarding the proper way to dispose of needles?
Discard the needles in a rigid and resistant container
69-Which of the following statements best represents the intravenous (IV) medications in the hospital facilities?
IV drugs transmits the highest risk of infection
31- Which of the following routes of drug administration provide 100% bio availability?
intraverous Injection
92- Which of the following is the expected bioavailability (F) of drugs given by intravenous route?
100%
3- Which of the following pharmaceutical activities should follow the USP chapter 797 standards?
Compounding of sterile preparations
32- Which of the following is the source for standards for compounding sterile preparations to be followed in the hospital pharmacy?
In United States Pharmacopeia (USP) chapter 797
34- Which of the following solutions is required for the reconstitution of parenteral formulations?
USP standard sterile water for injection
15) Which of the following is the most appropriate source for information on compounding medications ?
United states pharmacopeis (USP)
62- Which of the following resources is best to use for common compounding techniques and ingredients?
Remington: the science and practice of pharmacy
92-Which of the following type of water should be used for reconstitution of parenteral preparations?
Sterile water for injection
10. 10
23- Sterile preparation is a very complex manufacturing procedure that requires attention to the ingredients added in it. Which of the following
ingredients can be added when preparing a sterile drug?
Antioxidants
25- What is the route of administration of Enoxaparin?
Subcutaneous injection
68- An extemporaneous drug label says to store the drug between 15 and 25 degrees centigrade.Which of the following is the most appropriate
place where this drug should be stored?
cool room ….[cold room: 2-8 , cool room: 8-25 , room: 25-30, warm: 30-40]
56- A 25-year-old man with leukemia admitted to hematology oncology center.
Who is allowed to read the patient file without additional permission
Clinical nutritionist who is assigned to calculate the requires for the patient
29-A 48-year-old man patient is receiving parental nutrition (PN) at the following intravenous rate of infusion on daily basis: At 21:00 start PN at a
rate of 40 ml/hr x 1 Hr
At 22:00 increase Pn to a rate of 80 ml/Hr x 12
Hr At 10:00 reduce PN to a rate of 40 ml/Hr x1 Hr
At 11:00 stop PN
Which of the following best describes the mode of PN administration in this patient?
Cyclic PN
MEDICINES
92. The valid of tramadol prescription
1 month
36. A 10 years old take vancomycin 50mg/500ml
Over dose- ADR- not enough
41. which of the following drugs show most multidrug resistance ?
Antibiotics & anticancer
62. Drug that is susceptible to cause drug dependence ?
Benzodiazepines
121. which of the following drugs cause dependence
Benzodiazepenes
39. Fentanyl patch should avoid
Heat
21-which of the following instructions should be provided to a patient receiving fentanyl transdermal patches?
Avoid increase in body core temperature
100- Which of the following physicochemical characteristics of a drug decreases its transdermal penetration?
high melting point
52. Non linear kinetic ?
Phenytoin
45. linear pharmacokinetic parameter mean
clearance don "t changed
. which has narrow therapeutic index: Digoxin, Phenytoin
. A drug is dose dependant according to pharmacokinetic parameter: Phenytoin
(37) A 45-year-old male is admitted to the hospital for craniotomy Phenytoin has been prescribed to him after the surgery. Before initiation of
the drug the pharmacist suggested to do pharmacogenetics test and the results revealed that the patient carries the HLA-B*58:01 allele.
Which of the following adverse effects is associated with this patient's allele type?
severe cutaneous reaction
62)A 55-year-old man brought a prescription for Oxycontin on April year. The script from doctor is dated December 17 of last year prescription
allows five refills. What quantity of fill (s) isare likely to be received by the patient?
1 Today+1 Refill
(33) A 55-year-old man with a history of recurrent back pain is admitted to the hospital, he was prescribed paracetamol 1000 mg P.O Q6hr PRN
for 1 month available tablet is 500mg.
What is the maximum quantity given for a refill?
240 tablets
10- A nurse has an inquiry about the appropriate time to Withdraw a trough gentamicin level for a patient.
What is the best answer for her inquiry?
30 minutes after gentamicin administration
20- A pharmacist is working in a busy community pharmacy where has several patients at the counter. A patient brought to you for Sildenafil for
erectile dysfunction.
Which of the following is the best way of communication with you to provide counseling?
Ask the patient to move to a private area in the pharmacy hear you clearly and ask questions
13- The treatment of tuberculosis (AntiTB) involves multiple medication have to be taken for a long period of time.
Which of the following is the best way to ensure patient adherence AntiTB?
Apply Direct Observed Therapy, Short course strategy (DOT)
72- A 65-year-old man presents to the pharmacy for a refill his medications. On review of his refill history, the pharmacist noticed that he does not
refill his medications regularly. Upon asking him, the patient started that he has multiple medications that require complex administration.
Which of the following non adherence factors affecting above patient?
Medication and condition factor
11. 11
43) A 56-year-old farmer man has a significant history of animal contacts (goats and sheep) complains.of low grade fever (on/off) for 3 months,
lethargy, anorexia, cough and weight loss. He seeks a medical advice from a pharmacist at local pharmacy in the village. He asks for over the
counter (OTC) medications for his illness. Which of the following is the most appropriate recommendation?
refer him to the nearest hospital for further investigation
61) Which of the following is the best approach for your patient when his/here objective measures of adherence are inconsistent with the
subjective measures?
‟Sounds like you are not sure about how to take your medicine you show me how to take it ”
16) Which of the following measurements is used to assess patient adherence ?
A)Drug Utillization reviews B)Medication Event System
C)Medication Possession Ratio D)Medication therapy management
Medication therapy management, generally called medicine use review in the United kingdom, is a service provided typically by pharmacists that
aims to…
75-It is the broad range of health care services provided by in order to optimize therapeutic outcomes for individual patients .
Which of the following is the term used to describe the above- mentioned definition?
Medication therapy management
95- A patient is admitted to the hospital for the treatment of atrial fibrillation. During hospital stay, the patient receives IV diltiązem was discharge
on oral diltiązem plus his previous antihypertensive medication verapamil.
Which of the following medication error-reduction programs Would most likely have helped to prevent this duplication of therapy?
Medication Reconciliation
67) A patient visits pharmacy with fever and cough but has no prescription patients requests for acetaminophen, dextromethorphan syrup
,glycerin suppository and amoxicillin 500 mg capsules
Which of the following needs prescription for delivery?
Amoxicillin capsules
Adverse Effects
4)A 23 year-old man has recently been started on phenytoin for the treatment of epilepsy. He is taking no other medication he has noted recently
swelling and bleeding of the gum and wants to know if this might be drug related.
Meylers side effects of drugs
(1)Which of the following error detection strategies result in limiting detection?
mandatory reporting
49) Which of the following is the major risk associated with the use of over-the-counter drugs?
Increased risk of adverse events
47) Which of the following is reguired to consider an advers drug event report a valid report?
A)Drug dose C)Event name
28) Which of the following medication error is difficult to prevent ?
Allergic reactions to an unknown patient
54) Which of following prescriptions may have a potential to cause medication error ?
Amlodipine 5.0 mg PO OD
COMMUNICATION
11) Which of the following communication techniques is the most appropriate at the message you want to deliver to a patient (or healthcare
provider) is received correctly ?
Feedback
78-Which one of the following question's types is used to identify a certain piece of information?
Closed ended questions (yes or no)
15)Which one of the following questioning techniques uses hints and aid patients in answering questions?
Prompting while asking
13) Which of the following strategies are used with low literacy patients to Encourage them to change their behavior ?
Use more visual aids
39) Which of the following strategies are used with older adult patients to encourage them to change their behavior ?
Use teach-back more often throughout the session
19-A 62-year-old man who just had a needle biopsy of pancreas adenocarcinoma. A pharmacist saw his brother in the hall, and him not to tell the
patient because the knowledge would be very on his health.
A family conference to discuss the prognosis is scheduled for later that afternoon.
What is the way for the healthcare practitioner to handle the situation?
A) The healthcare practitioner should ask the patient how he the information in front of the rest of the family, and for some family discussion time
for this matter
B) The healthcare practitioner should honor the request of the member who is protecting his beloved brother from the patient
C) The healthcare practitioner should tell the patient withholding information is not permitted under any circum
D) The patient should withhold informing the patient about the 2 pancreatic cancer because of the grave diagnosi
