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DRUGS OF CHOICE CONDITION/SCENARIO DRUG OF CHOICE CLASS OF DRUG ORGANOPHOSPHATE POISONING ATROPINE ANTI MUSCARINIC NICOTINE POISONING ATROPINE ANTI MUSCARINIC MUSHROOM POISONING ATROPINE ANTI MUSCARINIC ATROPINE/BELLODONNA POISONING PHYSOSTIGMINE TERTIARY AMINE - CARBAMATES DATURA POISONING PHYSOSTIGMINE TERTIARY AMINE - CARBAMATES DIAGNOSIS OF MYASTHENIA GRAVIS EDROPHONIUM (TENSILON TEST) QUARTERNARY AMINE - CARBAMATES GENERALISED MYASTHENIA GRAVIS PYRIDOSTIGMINE QUARTERNARY AMINE - CARBAMATES OCULAR MYASTHENIA GRAVIS PYRIDOSTIGMINE QUARTERNARY AMINE - CARBAMATES MYASTHENIC CRISIS i.v. IMMUNOGLOBULINS NARCO ANALYSIS THIOPENTONE BARBITURATE XEROSTOMIA CEVIMELINE > PILOCARPINE MUSCARINIC AGONIST MOTION SICKNESS SCOPOLAMINE PATCH ANTI MUSCARINIC URGE INCONTINENCE DARIFENACINE ANTI MUSCARINIC STRESS INCONTINENCE DULOXETINE α1 AGONIST OVERFLOW INCONTINENCE NEOSTIGMINE / BETHANECHOL M3 AGONIST PARALYTIC ILEUS BETHANECHOL M3 AGONIST COCAINE POISONING DIAZEPAM BENZODIAZEPINES COCAINE DEPENDANCE BROMOCRIPTINE DOPAMINE AGONIST HUNTINGTON'S CHOREA TETRABENAZINE VMAT-2 BLOCKER TARDIVE DYSKINESIA VALBENAZINE / TETRABENAZINE VMAT-2 BLOCKER ANAPHYLACTIC SHOCK i.m. EPINEPHRINE CATECHOLAMINES SEPTIC SHOCK / VASODILATORY SHOCK i.v. NOREPINEPHRINE CATECHOLAMINES BRITTLE ASTHMA EPINEPHRINE CATECHOLAMINES CARDIAC ARREST (ACLA GUIDELINES) EPINEPHRINE CATECHOLAMINES CARDIOGENIC SHOCK NOREPINEPHRINE > DOPAMINE CATECHOLAMINES CHF WITH OLIGURIA DOPAMINE CATECHOLAMINES ACUTE CHF DOBUTAMINE CATECHOLAMINES STRESS ECHO DOBUTAMINE CATECHOLAMINES NEUROGENIC HYPOTENSION DROXIDOPA CATECHOLAMINES PRIAPISM PHENYLEPHRINE (Intracavernosal) α1 AGONIST ACUTE POSTURAL HYPOTENSION MIDODRINE α1 AGONIST AUTONOMIC NERVOUS SYSTEM Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE LONG TERM POSTURAL HYPOTENSION FLUDROCORTISONE CORTICOSTEROIDS HYPERTENSIVE URGENCY CLONIDINE α2 AGONIST TICS WITH TOURETTE SYNDROME CLONIDINE α2 AGONIST PREGNANCY INDUCED HYPERTENSION LABETALOL β BLOCKER HYPOTENSION WITH SPINAL ANESTHESIA EPHEDRINE INDIRECT SYMPATHOMIMETIC ADHD METHYLPHENIDATE INDIRECT SYMPATHOMIMETIC ADHD WITH TOURETTE SYNDROME ATOMOXETINE INDIRECT SYMPATHOMIMETIC ADHD WITH FAMILY H/O DRUG ABUSE ATOMOXETINE INDIRECT SYMPATHOMIMETIC NARCOLEPSY MODAFINIL CLONIDINE WITHDRAWAL HYPERTENSION PHENTOLAMINE NON SELECTIVE α BLOCKER CHEESE REACTION PHENTOLAMINE NON SELECTIVE α BLOCKER INTRAOPERATIVE HYPERTENSION IN PHEOCHROMOCYTOMA PHENTOLAMINE NON SELECTIVE α BLOCKER PREOPERATIVE HYPERTENSION IN PHEOCHROMOCYTOMA PHENOXYBENZAMINE NON SELECTIVE α BLOCKER BENIGN PROSTATIC HYPERPLASIA ALFUZOSIN α1a BLOCKER BPH WITH HYPERTENSION DOXAZOSIN α1 BLOCKER HYPERTENSION WITH DYSLIPIDEMIA DOXAZOSIN α1 BLOCKER SCORPION BITE PRAZOSIN α1 BLOCKER HYPERTENSION WITH ANXIETY PROPRANOLOL β BLOCKER HYPERTENSION WITH HYPERTHYROIDISM PROPRANOLOL β BLOCKER HYPERTENSION WITH MIGRAINE PROPRANOLOL β BLOCKER HYPERTENSION WITH H/o MI PROPRANOLOL β BLOCKER HYPERTENSION WITH CHRONIC CHF PROPRANOLOL β BLOCKER HYPERTENSION WITH STABLE ANGINA PROPRANOLOL β BLOCKER PROPHYLAXIS OF MIGRAINE PROPRANOLOL β BLOCKER STABLE ANGINA PROPRANOLOL β BLOCKER PROPHYLAXIS OF STABLE ANGINA PROPRANOLOL β BLOCKER AORTIC DISSECTION PROPRANOLOL β BLOCKER HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY PROPRANOLOL β BLOCKER PROPHYLAXIS OF ACUTE VARICEAL BLEED PROPRANOLOL β BLOCKER ULCERATED INFANTILE HEMANGIOMA PROPRANOLOL β BLOCKER ESSENTIAL TREMOR PROPRANOLOL β BLOCKER BETA BLOCKER POISONING GLUCAGON Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE OPEN ANGLE GLAUCOMA LATANOPROST PGF2α ANALOGUE NORMAL TENSION GLAUCOMA LATANOPROST PGF2α ANALOGUE ACUTE CONGESTIVE GLAUCOMA ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR CYCLOPLEGIA - ADULTS TROPICAMIDE ANTI MUSCARINIC CYCLOPLEGIA - CHILDREN ATROPINE ANTI MUSCARINIC FAMILIAL HYPERKALEMIC PERIODIC PARALYSIS DICHLORPHENAMIDE CARBONIC ANHYDRASE INHIBITOR INCREASED ICP HEADACHE (PSEUDOTUMOR CEREBRI) ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR MOUNTAIN SICKNESS ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR MORNING SICKNESS DOXYLAMINE ANTI HISTAMINIC HAY FEVER (ALLERGIC RHINITIS) CORTICOSTEROIDS URTICARIA SECOND GENERATION ANTI HISTAMINICS ACUTE ATTACK OF MIGRAINE SUMATRIPTAN 5HT 1B/1D AGONIST CLUSTER HEADACHE SUMATRIPTAN 5HT 1B/1D AGONIST PROPHYLAXIS OF CLUSTER HEADACHE VERAPAMIL CALCIUM CHANNEL BLOCKER HEREDITARY ANGIOEDEMA - TREATMENT C1 ESTERASE INHIBITOR HEREDITARY ANGIOEDEMA - PROPHYLAXIS DANAZOL TESTOSTERONE ANALOGUE HEREDITARY TREATMENT PROPHYLAXIS - PRIOR TO SURGERY € AMINO CAPROIC ACID ANTI FIBRINOLYTICS CERVICAL RIPENING DINOPROSTONE PGE2 ANALOGUE PARACETAMOL POISONING N ACETYLCYSTEINE NIACIN INDUCED FLUSHING ASPIRIN NON-SELECTIVE COX INHIBITOR ACUTE GOUT INDOMETHACIN NON-SELECTIVE COX INHIBITOR BARTTER SYNDROME INDOMETHACIN NON-SELECTIVE COX INHIBITOR PAROXYSMAL HEMICRANIA INDOMETHACIN NON-SELECTIVE COX INHIBITOR CLOSURE OF PATENT DUCTUS ARTERIOSUS IBUPROFEN NON-SELECTIVE COX INHIBITOR FAMILIAL MEDITERRANEAN FEVER COLCHICINE MICROTUBULE INHIBITOR CHRONIC GOUT ALLOPURINOL XANTHINE OXIDASE INHIBITOR TUMOR LYSIS SYNDROME PROPHYLAXIS ALLOPURINOL XANTHINE OXIDASE INHIBITOR AUTOCOIDS CARDIOVASCULAR SYSTEM Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE ACUTE ATTACK OF SVT/PSVT ADENOSINE PROPHYLAXIS OF SVT/PSVT PROPRANOLOL β BLOCKER WPW SYNDROME WITH ATRIAL FIBRILLATION PROCAINAMIDE CLASS 1A ANTI ARRHYTHMIC WPW SYNDROME RF ABLATION > FLECAINIDE CLASS 1C ANTI ARRHYTHMIC DIGOXIN INDUCED VT / V. FIBRILLATION LIDOCAINE CLASS 1B ANTI ARRHYTHMIC MI INDUCED VT / V. FIBRILLATION LIDOCAINE CLASS 1B ANTI ARRHYTHMIC IDIOPATHIC VT PROPRANOLOL β BLOCKER VENTRICULAR PREMATURE BEATS PROPRANOLOL β BLOCKER RATE CONTROL IN ATRIAL FIBRILLATION - STABLE PT METOPROLOL β BLOCKER RATE CONTROL IN ATRIAL FIBRILLATION - UNSTABLE PT ESMOLOL β BLOCKER RHYTHM CONTROL IN ATRIAL FIBILLATION/FLUTTER AMIODARONE CLASS 3 ANTI ARRHYTHMIC ANTI ARRHYTHMIC OF CHOICE IN ACLS PROTOCOL AMIODARONE CLASS 3 ANTI ARRHYTHMIC VENTRICULAR TACHYCARDIA AMIODARONE CLASS 3 ANTI ARRHYTHMIC VENTRICULAR FIBRILLATION AMIODARONE CLASS 3 ANTI ARRHYTHMIC ACUTE ATTACK OF ATRIAL FIB / ATRIAL FLUTTER DC CARDIOVERSION PSVT WITH BRONCHIAL ASTHMA VERAPAMIL CLASS 4 ANTI ARRHYTHMIC PSVT WITH COPD VERAPAMIL CLASS 4 ANTI ARRHYTHMIC LONG QT SYNDROME - PROPHYLAXIS PROPRANOLOL β BLOCKER LONG QT SYNDROME - ACUTE ATTACK MAGNESIUM SULPHATE BRADYARRHYTHMIA d/t IWMI ATROPINE ANTI MUSCARINIC BRADYARRHYTHMIA d/t SINUS ARREST ATROPINE ANTI MUSCARINIC ACUTE CHF WITH PULMONARY EDEMA FUROSEMIDE DIURETIC RIGHT SIDED HEART FAILURE MILRINONE PDE 3 INHIBITOR RAYNAUD'S DISEASE VERAPAMIL CALCIUM CHANNEL BLOCKER HYPERTENSIVE EMERGENCY i.v. NICARDIPINE CALCIUM CHANNEL BLOCKER HYPERTENSIVE EMERGENCY IN PREGNANCY i.v. LABETOLOL β BLOCKER INSULINOMA DIAZOXIDE POTASSIUM CHANNEL OPENER ACUTE ATTACK OF ANGINA sl. NITROGLYCERIN VENODILATOR PROPHYLAXIS OF ANGINA PAIN IN MI sl. NITROGLYCERIN VENODILATOR CYANIDE POISONING AMYL NITRITE VENODILATOR MALIGNANT HYPERTENSION SODIUM NITROPRUSSIDE MIXED VASODILATOR HYPERTENSION WITH DM ACEI / ARB HYPERTENSION WITH CKD ACEI / ARB Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE HYPERTENSION WITH NEPHROTIC SYNDROME ACEI / ARB HYPERTENSION WITH SCLERODERMA ACEI / ARB HYPERTENSION WITH BILATERAL RENAL STENOSIS CALCIUM CHANNEL BLOCKER HYPERTENSION - YOUNG PATIENT ACEI / ARB HYPERTENSION - OLD PATIENT CALCIUM CHANNEL BLOCKER HYPERTENSION WITH OSTEOPOROSIS CHLORTHALIDONE THIAZIDES RESISTANT HYPERTENSION SPIRONOLACTONE ALDOSTERONE ANTAGONIST RESISTANT EDEMA SPIRONOLACTONE ALDOSTERONE ANTAGONIST CIRRHOTIC EDEMA SPIRONOLACTONE ALDOSTERONE ANTAGONIST CEREBRAL EDEMA MANNITOL OSMOTIC DIURETICS PULMONARY EDEMA FUROSEMIDE LOOP DIURETICS TYPE II HYPERLIPOPROTEINEMIA STATINS TYPE II HYPERLIPOPROTEINEMIA IN PREGNANCY / CHILDREN BILE ACID BINDING RESINS HYPERCHYLOMICRONEMIA TYPE I HYPERLIPOPROTEINEMIA FIBRATES TYPE III HYPERLIPOPROTEINEMIA FIBRATES HYPERTRIGLYCERIDEMIA / TYPE IV HYPERLIPOPROTEINEMIA FIBRATES DIABETIC KETOACIDOSIS REGULAR INSULIN TYPE 2 DIABETES MELLITUS METFORMIN BIGUANIDES ACROMEGALY OCTREOTIDE SOMATOSTATIN ANALOGUE ACUTE VARICEAL BLEED OCTREOTIDE SOMATOSTATIN ANALOGUE SECRETORY DIARRHOEA (HIV/TUMOR/CHEMOTHERAPY) OCTREOTIDE SOMATOSTATIN ANALOGUE GLUCAGONOMA OCTREOTIDE SOMATOSTATIN ANALOGUE VIPOMA OCTREOTIDE SOMATOSTATIN ANALOGUE SOMATOSTATINOMA OCTREOTIDE SOMATOSTATIN ANALOGUE CARCINOID SYNDROME OCTREOTIDE SOMATOSTATIN ANALOGUE PROSTATE CANCER Continous Dosage of GOSERELIN + FLUTAMIDE GnRH AGONIST + ANDROGEN RECEPTOR ANTAGONIST RIEDELS THYROIDITIS TAMOXIFEN SERM ENDOCRINE SYSTEM Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE ER +VE BREAST CANCER IN PRE MENOPAUSAL WOMEN TAMOXIFEN SERM ER +VE BREAST CANCER IN POST MENOPAUSAL WOMEN LETROZOLE AROMATASE INHIBITOR ANDROGENIC ALOPECIA FINASTERIDE 5α REDUCTASE INHIBITOR HYPERTHYROIDISM METHIMAZOLE THYROID PEROXIDASE INHIBITOR HYPERTHYROIDISM IN PREGNANCY (2nd & 3rd TRIMESTER) METHIMAZOLE THYROID PEROXIDASE INHIBITOR HYPERTHYROIDISM IN PREGNANCY (1st TRIMESTER) PROPYL THIOURACIL THYROID PEROXIDASE INHIBITOR SEVERE THYROTOXICOSIS / THYROID STORM PROPYL THIOURACIL THYROID PEROXIDASE INHIBITOR HYPOTHYROIDISM LEVOTHYROXINE SODIUM SALT OF T4 SUBACUTE / DEQUERVAIN THYROIDITIS ASPIRIN NON-SELECTIVE COX INHIBITOR CONGENITAL ADRENAL HYPERPLASIA (CAH) HYDROCORTISONE CORTICOSTEROIDS ANTENATAL PROPHYLAXIS OF CAH DEXAMETHASONE CORTICOSTEROIDS PRIMARY ADDISON'S DISEASE HYDROCORTISONE + FLUDROCORTISONE CORTICOSTEROIDS SECONDARY ADDISON'S DISEASE HYDROCORTISONE CORTICOSTEROIDS OSTEOPOROSIS ZOLENDRONATE BISPHOSPHONATES HYPERCALCEMIA OF MALIGNANCY ZOLENDRONATE BISPHOSPHONATES PAGETS DISEASE ZOLENDRONATE BISPHOSPHONATES POST PARTUM HEMORRHAGE OXYTOCIN GENERALIZED TONIC CLONIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER MYOCLONIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER ATONIC / AKINETIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER ABSENCE SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER LENNOUX GASTAUT SYNDROME SODIUM VALPROATE CALCIUM CHANNEL BLOCKER DRAVET SYNDROME SODIUM VALPROATE CALCIUM CHANNEL BLOCKER RAPID CYCLERS IN BIPOLAR DISORDER SODIUM VALPROATE CALCIUM CHANNEL BLOCKER REFRACTORY INTRACTABLE RHEUMATIC CHOREA SODIUM VALPROATE CALCIUM CHANNEL BLOCKER ABSENCE SEIZURES IN CHILDREN < 2 YRS ETHOSUXIMIDE CALCIUM CHANNEL BLOCKER PARTIAL SEIZURE CARBAMAZEPINE SODIUM CHANNEL BLOCKER ROLANDIC EPILEPSY CARBAMAZEPINE SODIUM CHANNEL BLOCKER GLOSSOPHARYNGEAL NEURALGIA CARBAMAZEPINE SODIUM CHANNEL BLOCKER TRIGEMINAL NEURALGIA (TIC DOLOUREX) CARBAMAZEPINE SODIUM CHANNEL BLOCKER CENTRAL NERVOUS SYSTEM Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE JME IN PREGNANCY LAMOTRIGENE SODIUM CHANNEL BLOCKER INFANTILE SPASMS WITH TUBEROUS SCLEROSIS VIGABATRIN GABA TRANSAMINASE BLOCKERS INFANTILE SPASMS WITHOUT TUBEROUS SCLEROSIS ACTH > STEROIDS FEBRILE SEIZURES p.r. DIAZEPAM BENZODIAZEPINES STATUS EPILEPTICUS i.v. LORAZEPAM BENZODIAZEPINES STATUS EPILEPTICUS IN PREGNANCY THIOPENTONE SODIUM BARBITURATES ALCOHOL WITHDRAWAL CHLORDIAZEPOXIDE BENZODIAZEPINES ALCOHOL DEPENDENCE CHLORDIAZEPOXIDE BENZODIAZEPINES HICCUPS CHLORPROMAZINE PHENOTHIAZINE CATATONIA LORAZEPAM BENZODIAZEPINES JET LAG ZOLEPLON Z COMPOUNDS INSOMNIA (SLEEP INDUCTION) ZOLEPLON Z COMPOUNDS INSOMNIA (SLEEP MAINTENANCE) ESZOPICLONE Z COMPOUNDS NEONATAL SEIZURES PHENOBARBITOL BARBITURATES CRIGLER NAJJAR SYNDROME PHENOBARBITOL BARBITURATES POST OPERATIVE CHILLS MEPERIDINE / PETHIDINE OPIOD AGONISTS BENZODIAZEPINE / Z COMPOUND TOXICITY FLUMAZENIL OPIOD TOXICITY NALOXONE OPIOD ANTAGONIST OPIOD DEPENDANCE (RELAPSE PREVENTION) NALTREXONE OPIOD ANTAGONIST MANIA PROPHYLAXIS LITHIUM BIPOLAR DISEASE PROPHYLAXIS LITHIUM HYPNIC HEADACHE LITHIUM LITHIUM INDUCED DIABETES INSIPIDUS AMILORIDE EPITHELIAL SODIUM CHANNEL BLOCKER CENTRAL DIABETES INSIPIDUS DESMOPRESSIN VASOPRESSIN ANALOGUE NOCTURNAL ENURESIS DESMOPRESSIN VASOPRESSIN ANALOGUE SIADH REDUCE FREE WATER INTAKE > TOLVAPTAN SELECTIVE V2 RECEPTOR BLOCKER NEUROPATHIC PAIN AMITRIPTYLINE TRICYCLIC ANTI DEPRESSANT POST HERPETIC NEURALGIA AMITRIPTYLINE TRICYCLIC ANTI DEPRESSANT DEPRESSION FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR PRE MENSTRUAL SYNDROME FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR OBSESSIVE COMPULSIVE DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR PHOBIAS FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR POST TRAUMATIC STRESS DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE SOCIAL ANXIETY FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR GENERALIZED ANXIETY DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR BULIMIA NERVOSA FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR ANOREXIA NERVOSA FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR DEPRESSION WITH INSOMNIA MIRTAZAPINE NOR ADRENERGIC & SERATONERGIC ALZHEIMERS DISEASE RIVASTIGMINE/GALANTAMINE CHOLINERGICS SEVERE ALZHEIMERS DISEASE DONEPEZIL CHOLINERGICS PARKINSON'S DISEASE LEVODOPA DOPAMINE PRECURSOR PARKINSON'S - NON SEVERE / NON INTERFERING SELEGILINE MAO-B INHIBITORS PARKINSON'S - SEVERE / INTERFERING (<65 YRS) PRAMIPEXOLE DOPAMINE AGONIST PARKINSON'S - SEVERE / INTERFERING (>65 YRS) LEVODOPA DOPAMINE PRECURSOR PARKINSONS DISEASE - ON PERIOD - PROLONGATION ENTECAPONE COMT INHIBITORS PARKINSONS DISEASE - OFF PERIOD - RESCUE APOMORPHINE DRUG INDUCED PARKINSONS DISEASE TRIHEXYPHENIDYL (BENZHEXOL) ANTI MUSCARINIC HYPERPROLACTINEMIA CABERGOLINE DOPAMINE AGONIST HYPERPROLACTINEMIA IN PREGNANCY BROMOCRIPTINE DOPAMINE AGONIST HYPERPROLACTINEMIA IN INFERTILITY / OBESITY BROMOCRIPTINE DOPAMINE AGONIST RESTLESS LEG SYNDROME ROPINIROLE DOPAMINE AGONIST ACUTE DYSTONIA BENZTROPINE ANTI MUSCARINIC AKATHISIA PROPRANOLOL β BLOCKER NEUROLEPTIC MALIGNANT SYNDROME DANTROLENE RESISTANT SCHIZOPHRENIA CLOZAPINE ATYPICAL ANTIPSYCHOTICS SUICIDAL TENDENCY ECT > CLOZAPINE ATYPICAL ANTIPSYCHOTICS SCHIZOPHRENIA ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS ACUTE ATTACK OF MANIA ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS MANIA IN PREGNANCY ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS LEVODOPA INDUCED PSYCHOSIS QUETIAPINE ATYPICAL ANTIPSYCHOTICS RELAPSING REMITTING MULTIPLE SCLEROSIS INTERFERON β PROGRESSIVE RELAPSING MULTIPLE SCLEROSIS MITOXANTRONE ACUTE ATTACK OF MULTIPLE SCLEROSIS METHYL PREDNISOLONE CORTICOSTEROIDS BELL'S PALSY PREDNISOLONE CORTICOSTEROIDS Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE ACUTE ATTACK OF BRONCHIAL ASTHMA LOW DOSE FLUTICASONE + FORMOTEROL ICS + LABA COPD TIOTROPIUM/UMECLIDINIUM ANTI MUSCARINIC PERSISTENT BRONCHIAL ASTHMA FLUTICASONE + FORMOTEROL ICS + LABA LONGTERM FOR EXERCISE INDUCED ASTHMA FLUTICASONE INHALATIONAL CORTICOSTEROIDS PULMONARY HYPERTENSION STAGE II/III BOSENTAN ENDOTHELIN ANTAGONIST PULMONARY HYPERTENSION STAGE IV EPOPROSTERENOL PGI2 ANALOGUE RECURRENT APNEA OF PREMATURITY CAFFEINE METHYLXANTHINES ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS (ABPA) PREDNISOLONE CORTICOSTEROIDS PROLIFERATIVE BRONCHIOLITIS PREDNISOLONE CORTICOSTEROIDS CRYPTOGENIC ORGANIZING PNEUMONIA / BRONCHIOLITIS OBLITERANS ORGANISING PNEUMONIA PREDNISOLONE CORTICOSTEROIDS EOSINOPHILIC PNEUMONIA PREDNISOLONE CORTICOSTEROIDS SARCOIDOSIS PREDNISOLONE CORTICOSTEROIDS ANEMIA d/t CHEMOTHERAPY ERYTHROPOIETIN ANALOGUE ANEMIA d/t CHRONIC RENAL FAILURE ERYTHROPOIETIN ANALOGUE ANEMIA d/t ZIDOVUDINE ERYTHROPOIETIN ANALOGUE ANEMIA d/t DIALYSIS ERYTHROPOIETIN ANALOGUE NEUTROPENIA d/t CHEMOTHERAPY FILGRASTIM GRANULOCYTE - CSF NEUTROPENIA d/t HIV FILGRASTIM GRANULOCYTE - CSF THROMBOPROPHYLAXIS IN NON VALVULAR ATRIAL FIBRILLATION DABIGATRAN + EDOXABAN DIRECT ORAL ANTICOAGULANTS THROMBOPROPHYLAXIS AFTER ELECTIVE HIP/KNEE ARTHROPLASTY RIVAROXABAN FACTOR Xa INHIBITOR HEPARIN INDUCED THROMBOCYTOPENIA ARGATROBAN DIRECT THROMBIN INHIBITOR CATHETER INDUCED THROMBOSIS UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR THROMBOSIS IN CARDIOPULMONARY BYPASS UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR CONCURRENT THROMBOLYSIS WITH INCREASED RISK OF BLEEDING UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR THROMBOSIS IN MI LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR RESPIRATORY SYSTEM HEMATOLOGY Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE THROMBOSIS IN UNSTABLE ANGINA LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR DEEP VEIN THROMBOSIS LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR PULMONARY EMBOLISM LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR CANCER INDUCED THROMBOSIS LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR PROPHYLAXIS OF THROMBOSIS IN VALVULAR ATRIAL FIBRILLATION WARFARIN PROPHYLAXIS OF DEEP VENOUS THROMBOSIS WARFARIN PROPHYLAXIS OF PULMONARY EMBOLISM WARFARIN PROPHYLAXIS OF THROMBOSIS d/t MECHANICAL VALVE DURING PREGNANCY WARFARIN ANTI PHOSPHOLIPID ANTIBODY SYNDROME WARFARIN ANTI PHOSPHOLIPID ANTIBODY SYNDROME IN PREGNANCY ASPIRIN + (LMWH> UFH) THROMBOLYSIS INDUCED BLEEDING € AMINO CAPROIC ACID PEPTIC ULCER DISEASE OMEPRAZOLE PROTON PUMP INHIBITIOR NSAID INDUCED ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR STRESS ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR GERD OMEPRAZOLE PROTON PUMP INHIBITIOR ZOLLINGER ELLISON SYNDROME OMEPRAZOLE PROTON PUMP INHIBITIOR H.PYLORI ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR GERD IN PREGNANCY/ CHILDREN ANTACIDS PROPHYLAXIS OF ASPIRATION PNEUMONIA IN POST OP PTS RANITIDINE H2 BLOCKERS CHEMOTHERAPY INDUCED NAUSEA & VOMITING - EARLY ONSET ONDANSETRON 5HT3 RECEPTOR BLOCKERS CHEMOTHERAPY INDUCED NAUSEA & VOMITING - LATE ONSET APREPITANT NK1 RECEPTOR ANTAGONISTS IBS WITH CONSTIPATION POLYETHYLENE GLYCOL IBS WITH VISCERAL PAIN TRICYCLIC ANTIDEPRESSANTS IBS WITH DIARRHOEA LOPERAMIDE OPIOD AGONISTS GASTROINTESTINAL SYSTEM Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE NON SECRETORY DIARRHOEA LOPERAMIDE OPIOD AGONISTS ULCERATIVE COLITIS - MILD / MODERATE MESALAMINE 5 ASA ANALOGUE ULCERATIVE COLITIS - SEVERE BUDESONIDE CORTICOSTEROIDS ULCERATIVE COLITIS - STEROID DEPENDANT AZATHIOPRINE PURINE SYNTHESIS INHIBITORS ULCERATIVE COLITIS - STEROID RESISTANT CYCLOSPORINE CALCINEURIN INHIBITORS PROPHYLAXIS OF ULCERATIVE COLITIS MESALAMINE 5 ASA ANALOGUE CROHN'S DISEASE - MILD / MODERATE PREDNISOLONE CORTICOSTEROIDS CROHN'S DISEASE - SEVERE (WITH FISTULA) INFLIXIMAB ANTI TNF-α PROPHYLAXIS OF CROHN'S DISEASE INFLIXIMAB ANTI TNF-α HEMOCHROMATOSIS DEFEROXAMINE IRON CHELATOR NEPHROTIC SYNDROME GLUCOCORTICOIDS STEROIDS STEROID DEPENDANT NEPHROTIC SYNDROME CYCLOPHOSPHAMIDE NITROGEN MUSTARDS STEROID RESISTANT NEPHROTIC SYNDROME CYCLOSPORINE CALCINEURIN INHIBITORS LUPUS NEPHRITIS CYCLOPHOSPHAMIDE + GLUCORTICOIDS NITROGEN MUSTARDS + STEROIDS CYSTINURIA TIOPRONIN + POTASSIUM CITRATE CYSTEINE BINDER + URINE ALKALINIZER MRSA (STAPHYLOCOCCAL ENDOCARDITIS) VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS PSEUDOMEMBRANOUS ENTEROCOLITIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS PNEUMOCOCCAL MENINGITIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS ENTEROCOCCUS FAECIUM VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS ENTEROCOCCUS FAECALIS AMPICILLIN AMINOPENICILLINS AMPICILLIN RESISTANT ENTEROCOCCUS FAECALIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS LISTERIA AMPICILLIN AMINOPENICILLINS HEMOPHILUS INFLUENZAE - PNEUMONIA/OTITIS MEDIA AMPICILLIN AMINOPENICILLINS STREPTOCOCCAL ENDOCARDITIS AMPICILLIN AMINOPENICILLINS ENTEROCOCCAL ENDOCARDITIS AMPICILLIN AMINOPENICILLINS VRSA DAPTOMYCIN LIPOPEPTIDES EMPERICAL MRSA DAPTOMYCIN LIPOPEPTIDES SYPHILIS - ALL STAGES BENZATHINE PENICILLIN G NARROW SPECTRUM PENICILLINS ANTIMICROBIALS RENAL SYSTEM Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE SYPHILIS - CNS STAGES AQUEOUS PENICILLIN G NARROW SPECTRUM PENICILLINS STREPTOCOCCUS PENICILLIN G NARROW SPECTRUM PENICILLINS YAWS PENICILLIN G NARROW SPECTRUM PENICILLINS ACTINOMYCOSIS PENICILLIN G NARROW SPECTRUM PENICILLINS LEPTOSPIROSIS PENICILLIN G NARROW SPECTRUM PENICILLINS GAS GANGRENE PENICILLIN G NARROW SPECTRUM PENICILLINS RAT BITE FEVER PENICILLIN G NARROW SPECTRUM PENICILLINS MASTITIS CLOXACILLIN PENICILLINASE RESISTANT PENICILLINS SURGICAL PROPHYLAXIS CEPHAZOLIN 1st GENERATION CEPHALOSPORINS GONORRHOEA CEFTRIAXONE + AZITHROMYCIN 3rd GENERATION CEPHALOSPORINS CEFTRIAXONE RESISTANT GONORRHOEA SPECTINOMYCIN AMINOGLYCOSIDES E. COLI CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS KLEBSIELLA CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS PROVIDENCIA CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS EMPIRICAL OSTEOMYELITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS EMPERICAL MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS HEMOPHILUS INFLUENZA MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS MENINGOCOCCAL MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS TYPHOID CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS TYPHOID (ORAL DOC) CEFIXIME 3rd GENERATION CEPHALOSPORINS PSEUDOMONAS CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS MELIOIDOSIS / BURKHOLDERIA CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS FEBRILE NEUTROPENIA CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS ESBL PRODUCING ORGANISMS IMIPENEM CARBAPENEMS SERRATIA IMIPENEM CARBAPENEMS ENTEROBACTER IMIPENEM CARBAPENEMS ACINETOBACTER IMIPENEM CARBAPENEMS VRSA PNEUMONIA LINEZOLID OXAZOLIDINONE VRE LINEZOLID OXAZOLIDINONE MYCOPLASMA HOMINIS - STD DOXYCYCLINE TETRACYCLINES UREAPLASMA - STD DOXYCYCLINE TETRACYCLINES PROPHYLAXIS OF PLAGUE DOXYCYCLINE TETRACYCLINES RICKETTSIA DOXYCYCLINE TETRACYCLINES Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE BRUCELLA DOXYCYCLINE TETRACYCLINES BORELLIA DOXYCYCLINE TETRACYCLINES CHLAMYDIA (LGV) DOXYCYCLINE TETRACYCLINES CHOLERA DOXYCYCLINE TETRACYCLINES BARTONELLA DOXYCYCLINE TETRACYCLINES PLEURODESIS DOXYCYCLINE TETRACYCLINES PERICARDIODESIS DOXYCYCLINE TETRACYCLINES PLAGUE GENTAMICIN AMINOGLYCOSIDES TULAREMIA GENTAMICIN AMINOGLYCOSIDES GUT STERILIZATION IN HEPATIC ENCEPHALOPATHY RIFAMIXIN DIPHTHERIA ERYTHROMYCIN MACROLIDES PERTUSSIS ERYTHROMYCIN MACROLIDES PROPHYLAXIS OF RHEUMATIC FEVER IN PENICILLIN ALLERGY ERYTHROMYCIN MACROLIDES ATYPICAL PNEUMONIA (MYCOPLASMA, CHLAMYDIA, LEGIONELLA) AZITHROMYCIN MACROLIDES CAMPYLOBACTER AZITHROMYCIN MACROLIDES CHANCROID AZITHROMYCIN MACROLIDES CHLAMYDIA AZITHROMYCIN MACROLIDES GRANULOMA INGUINALE AZITHROMYCIN MACROLIDES CHOLERA IN PREGNANCY / CHILDREN AZITHROMYCIN MACROLIDES TOXIC SHOCK SYNDROME CLINDAMYCIN + VANCOMYCIN ANAEROBIC INFECTION - SUPRADIAPHRAGMATIC (PREVOTELLA) CLINDAMYCIN LINCOSAMIDE ANTIBIOTICS STAPHYLOCOCCUS NASAL CARRIER Topical MUPIROCIN SHIGELLA CIPROFLOXACIN FLUOROQUINOLONES TRAVELLER'S DIARRHOEA CIPROFLOXACIN FLUOROQUINOLONES PYELONEPHRITIS CIPROFLOXACIN FLUOROQUINOLONES MENINGOCOCCAL CONTACTS / MASS PROPHYLAXIS CIPROFLOXACIN FLUOROQUINOLONES ANTHRAX CIPROFLOXACIN FLUOROQUINOLONES TYPHOID CARRIERS CIPROFLOXACIN FLUOROQUINOLONES PNEUMOCYSTIS COTRIMOXAZOLE SULFONAMIDES PROPHYLAXIS OF PNEUMOCYSTIS COTRIMOXAZOLE SULFONAMIDES Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE NOCARDIOSIS COTRIMOXAZOLE SULFONAMIDES ISOSPORIASIS COTRIMOXAZOLE SULFONAMIDES CYCLOSPORIASIS COTRIMOXAZOLE SULFONAMIDES SARCOCYSTOSIS COTRIMOXAZOLE SULFONAMIDES CYSTITIS COTRIMOXAZOLE SULFONAMIDES PROSTATITIS COTRIMOXAZOLE SULFONAMIDES TOXOPLASMA SULFADIAZINE + PYRIMETHAMINE SULFONAMIDES TOXOPLASMA IN PREGNANCY SPIRAMYCIN MACROLIDES BURNS PATIENT TOPICAL SULFADIAZINE SULFONAMIDES PROPHYLAXIS OF TB (PT WITH HIV WITH LATENT INFECTION) ISONIAZID ISONIAZID INDUCED SEIZURES PYRIDOXINE DERMATITIS HERPETIFORMIS DAPSONE HERPES SIMPLEX VIRUS VALACYCLOVIR > ACYCLOVIR GUANINE ANALOGUES VARICELLA ZOSTER VIRUS VALACYCLOVIR > ACYCLOVIR GUANINE ANALOGUES CYTOMEGALOVIRUS VALAGANCYCLOVIR > GANCYCLOVIR GUANINE ANALOGUES RECURRENT LARYNGEAL PAPILLOMATOSIS CIDOFOVIR CYTIDINE ANALOGUES RESISTANT HERPES FOSCARNET GENITAL WARTS (HPV) - MALE PODOPHYLLIN TOXIN MICROTUBULE INHIBITOR GENITAL WARTS (HPV) - NON PREGNANT FEMALE IMIQUIMOD TLR-7 AGONIST GENITAL WARTS (HPV) - PREGNANT FEMALE CRYOTHERAPY WITH LIQUID N2 (-196) INFLUENZA - A, B OSELTAMIVIR NEURAMINIDASE INHIBITORS BIRD FLU OSELTAMIVIR NEURAMINIDASE INHIBITORS OSELTAMIVIR RESISTANT INFLUENZA A / B / BIRD FLU ZANAMIVIR NEURAMINIDASE INHIBITORS HEPATITIS - B TENOFOVIR DNA POLYMERASE INHIBITORS HEPATITIS B WITH HEPATITIS D SUPERINFECTION INTERFERON α RESPIRATORY SYNCITIAL VIRUS INHALATIONAL RIBAVIRIN PROPHYLAXIS OF RSV s.c. PALIVIZUMAB HIV - PERINATAL TRANSMISSION NEVIRAPINE MUCORMYCOSIS AMPHOTERICIN B POLYENES ANTIFUNGALS SYSTEMIC FUNGAL INFECTIONS AMPHOTERICIN B POLYENES ANTIFUNGALS KALA AZAR AMPHOTERICIN B POLYENES ANTIFUNGALS PRIMARY AMOEBIC MENINGOENCEPHALITIS AMPHOTERICIN B POLYENES ANTIFUNGALS Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE CRYPTOCOCCAL MENINGITIS i.v. AMPHOTERICIN B + i.v. FLUCYTOSINE POLYENES ANTIFUNGALS CANDIDA ALBICANS FLUCONAZOLE AZOLES COCCIDIAL MENINGITIS FLUCONAZOLE AZOLES ENDEMIC MYCOSIS ITRACONAZOLE AZOLES SPOROTRICHOSIS ITRACONAZOLE AZOLES TINEA CRURIS ITRACONAZOLE AZOLES TINEA CORPORIS ITRACONAZOLE AZOLES INVASIVE ASPERGILLOSIS VORICONAZOLE AZOLES SCEDOSPORIUM VORICONAZOLE AZOLES TRICHOSPORIUM VORICONAZOLE AZOLES PROPHYLAXIS OF INVASIVE ASPERGILLOSIS POSACONAZOLE AZOLES PROPHYLAXIS OF FUNGAL INFECTION IN GVHD POSACONAZOLE AZOLES CANDIDA GLABRATA CASPOFUNGIN ECHINOCANDINS CANDIDA KRUSEI CASPOFUNGIN ECHINOCANDINS CANDIDA PARAPSILOSIS CASPOFUNGIN ECHINOCANDINS TRICHOPHYTON TERBINAFINE MICROSPORUM GRISEOFULVIN EPIDERMOPHYTON GRISEOFULVIN T. CAPITIS (KERION/BOGGY SWELLING) GRISEOFULVIN FUNGAL CORNEAL ULCER TOPICAL NATAMYCIN ECHINOCOCCUS GRANULARIS ALBENDAZOLE BENZIMIDAZOLES ECHINOCOCCUS MULTILOCULARIS ALBENDAZOLE BENZIMIDAZOLES NEUROCYSTICERCOSIS ALBENDAZOLE BENZIMIDAZOLES LIVER FLUKE TRICLOBENDAZOLE BENZIMIDAZOLES HOOK WORM ALBENDAZOLE BENZIMIDAZOLES ROUND WORM ALBENDAZOLE BENZIMIDAZOLES WHIP WORM ALBENDAZOLE BENZIMIDAZOLES TRICHINELLA SPIRALIS ALBENDAZOLE BENZIMIDAZOLES ENTEROBIUS VERMICURALIS ALBENDAZOLE BENZIMIDAZOLES THREAD WORM (STRONGYLOIDES) IVERMECTIN ONCHOCERCA VOLVULUS IVERMECTIN SCABIES (ORAL) IVERMECTIN SCABIES Topical PERMETHRIN Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE FILARIASIS DIETHYL CARBAMAZINE LOA LOA DIETHYL CARBAMAZINE DIPHYLLOBOTHRIUM LATUM PRAZIQUANTEL HYMENOLEPIS NANA PRAZIQUANTEL TAENIA SOLIUM (INTESTINAL) PRAZIQUANTEL TAENIA SAGINATA PRAZIQUANTEL LUNG FLUKE PRAZIQUANTEL SCHISTOSOMA PRAZIQUANTEL INTESTINAL AMOEBIASIS - ASYMPTOMATIC PARAMOMYCIN INTESTINAL AMOEBIASIS - SYMPTOMATIC METRONIDAZOLE NITROIMIDAZOLE EXTRAINTESTINAL AMOEBIASIS METRONIDAZOLE NITROIMIDAZOLE TETANUS METRONIDAZOLE NITROIMIDAZOLE GIARDIASIS METRONIDAZOLE NITROIMIDAZOLE GARDNERELLA VAGINALIS METRONIDAZOLE NITROIMIDAZOLE TRICHOMONIASIS METRONIDAZOLE NITROIMIDAZOLE ANAEROBIC INFECTION - INFRADIAPHRAGMATIC (BACTEROIDES) METRONIDAZOLE NITROIMIDAZOLE DRACUNCULIASIS METRONIDAZOLE NITROIMIDAZOLE VISCERAL LEISHMANIASIS i.v. AMPHOTERICIN B POLYENES ANTIFUNGALS VISCERAL LEISHMANIASIS (ORAL) MILTEFOSINE CUTANEOUS LEISHMANIASIS SODIUM STIBOGLYCUNATE TRYPANOSOMA - EARLY EAST AFRICAN SLEEPING SICKNESS SURAMINE TRYPANOSOMA - LATE EAST AFRICAN SLEEPING SICKNESS MELARSOPROL TRYPANOSOMA - EARLY WEST AFRICAN SLEEPING SICKNESS PENTAMIDINE TRYPANOSOMA - LATE WEST AFRICAN SLEEPING SICKNESS EFLORNITHINE TRYPANOSOMA - AMERICAN (CHAGA'S DISEASE) BENZNIDAZOLE CRYPTOSPORIDIOSIS NITAZOXANIDE RESISTANT GIARDIASIS NITAZOXANIDE PLASMODIUM OVALE CHLOROQUINE + PRIMAQUINE PLASMODIUM VIVAX CHLOROQUINE + PRIMAQUINE Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE RADICAL CURE / TERMINAL PROPHYLAXIS OF RELAPSE OF PLASMODIUM VIVAX/OVALE TAFENOQUINE > PRIMAQUINE PLASMODIUM FALCIPARUM ARTESUNATE + SULFADOXINE + PYRIMETHAMINE (+ PRIMAQUINE on Day 2) CHOROQUINE RESISTANT P. OVALE/VIVAX ARTESUNATE + SULFADOXINE + PYRIMETHAMINE (+ PRIMAQUINE on Day 2) MALARIA IN NORTH EASTERN STATES ARTEMETHER + LUMEFANTRINE PLASMODIUM VIVAX IN PREGNANCY CHLOROQUINE PLASMODIUM OVALE IN PREGNANCY CHLOROQUINE SEVERE FALCIPARUM IN PREGNANCY QUININE RESISTANT MALARIA IN PREGNANCY QUININE PLASMODIUM FALCIPARUM IN PREGNANCY (1st TRIMESTER) QUININE + CLINDAMYCIN PLASMODIUM FALCIPARUM IN PREGNANCY (2nd & 3rd TRIMESTER) ARTEMETHER + LUMEFANTRINE MALARIA PROPHYLAXIS (FOR TRAVEL < 6 WKS) DOXYCYCLINE MALARIA PROPHYLAXIS (FOR TRAVEL >6 WKS/ PREGNANCY) MEFLOQUINE BABESIOSIS ATOVAQUONE + AZITHROMYCIN WEGNER'S GRANULOMATOSIS CYCLOPHOSPHAMIDE NITROGEN MUSTARDS CYCLOPHOSPHAMIDE INDUCED HEMORRHAGIC CYSTITIS MESNA BRAIN TUMORS TEMOZOLOMIDE ALKYLATING AGENTS HEAD & NECK CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS ESOPHAGEAL CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS GASTRIC CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS UROGENITAL CANCER CISPLATIN PLATINUM COMPOUNDS ALK +VE NON SMALL CELL CARCINOMA LUNG CRIZONTINIB ALK INHIBITORS MESOTHELIOMA PEMETREXED ANTI FOLATE DRUGS PANCREATIC CA GEMCITABINE PYRIMIDINE ANALOGUES HEPATOCELLULAR CARCINOMA SORAFENIB VEGF RECEPTOR INHIBITORS GASTROINTESTINAL STROMAL TUMOUR IMATINIB TYROSINE KINASE INHIBITORS ANTI CANCER DRUGS Compiled by Dr. Bhargav Shreeram G.
DRUGS OF CHOICE CHORIOCARCINOMA METHOTREXATE ANTI FOLATE DRUGS CARCINOMATOUS MENINGITIS METHOTREXATE ANTI FOLATE DRUGS RHEUMATOID ARTHRITIS METHOTREXATE ANTI FOLATE DRUGS ERYTHRODERMIC PSORIASIS METHOTREXATE ANTI FOLATE DRUGS PSORIATIC ARTHRITIS METHOTREXATE ANTI FOLATE DRUGS CHRONIC PLAQUE PSORIASIS METHOTREXATE ANTI FOLATE DRUGS MILD PSORIASIS ACITRETIN ORAL RETINOIDS PSORIASIS IN HIV ACITRETIN ORAL RETINOIDS PUSTULAR PSORIASIS ACITRETIN ORAL RETINOIDS PUSTULAR PSORIASIS OF PREGNANCY (IMPETIGO HERPETIFORMIS) CYCLOSPORINE > ORAL STEROIDS CALCINEURIN INHIBITORS TUMOR LYSIS SYNDROME ALLOPURINOL PURINE ANALOGUES CML IMATINIB TYROSINE KINASE INHIBITORS MULTI TYROSINE KINASE RESISTANT CML OMACETAXINE HAIRY CELL LEUKEMIA CLADRIBINE PURINE ANALOGUES HISTIOCYTOSIS CLADRIBINE PURINE ANALOGUES MYELODYSPLASIA AZACITIDINE + DECITABINE PYRIMIDINE ANALOGUES MYELODYSPLASIA WITH 5q DELETION LENALIDOMIDE THALIDOMIDE DERIVATIVE ESSENTIAL THROMBOCYTHEMIA HYDROXYUREA SICKLE CELL ANAEMIA HYDROXYUREA POLYCYTHEMIA VERA ANAGRELIDE > HYDROXYUREA PROMYELOCYTIC LEUKEMIA (PML) RETINOIC ACID RETINOIC ACID RESISTANT PML ARSENIC TRIOXIDE HER 2 POSITIVE BREAST CANCER TRANZTUZUMAB / PERTUZUMAB HER 2 POSITIVE GASTRIC CANCER TRANZTUZUMAB / PERTUZUMAB RESISTANT HER 2 POSITIVE BREAST CANCER / GASTRIC CANCER LAPATINIB / NERATINIB RENAL CELL CANCER BEVACIZUMAB / SUNITINIB Compiled by Dr. Bhargav Shreeram G.

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DRUGS OF CHOICE - COMPILED.pdf

  • 1. DRUGS OF CHOICE CONDITION/SCENARIO DRUG OF CHOICE CLASS OF DRUG ORGANOPHOSPHATE POISONING ATROPINE ANTI MUSCARINIC NICOTINE POISONING ATROPINE ANTI MUSCARINIC MUSHROOM POISONING ATROPINE ANTI MUSCARINIC ATROPINE/BELLODONNA POISONING PHYSOSTIGMINE TERTIARY AMINE - CARBAMATES DATURA POISONING PHYSOSTIGMINE TERTIARY AMINE - CARBAMATES DIAGNOSIS OF MYASTHENIA GRAVIS EDROPHONIUM (TENSILON TEST) QUARTERNARY AMINE - CARBAMATES GENERALISED MYASTHENIA GRAVIS PYRIDOSTIGMINE QUARTERNARY AMINE - CARBAMATES OCULAR MYASTHENIA GRAVIS PYRIDOSTIGMINE QUARTERNARY AMINE - CARBAMATES MYASTHENIC CRISIS i.v. IMMUNOGLOBULINS NARCO ANALYSIS THIOPENTONE BARBITURATE XEROSTOMIA CEVIMELINE > PILOCARPINE MUSCARINIC AGONIST MOTION SICKNESS SCOPOLAMINE PATCH ANTI MUSCARINIC URGE INCONTINENCE DARIFENACINE ANTI MUSCARINIC STRESS INCONTINENCE DULOXETINE α1 AGONIST OVERFLOW INCONTINENCE NEOSTIGMINE / BETHANECHOL M3 AGONIST PARALYTIC ILEUS BETHANECHOL M3 AGONIST COCAINE POISONING DIAZEPAM BENZODIAZEPINES COCAINE DEPENDANCE BROMOCRIPTINE DOPAMINE AGONIST HUNTINGTON'S CHOREA TETRABENAZINE VMAT-2 BLOCKER TARDIVE DYSKINESIA VALBENAZINE / TETRABENAZINE VMAT-2 BLOCKER ANAPHYLACTIC SHOCK i.m. EPINEPHRINE CATECHOLAMINES SEPTIC SHOCK / VASODILATORY SHOCK i.v. NOREPINEPHRINE CATECHOLAMINES BRITTLE ASTHMA EPINEPHRINE CATECHOLAMINES CARDIAC ARREST (ACLA GUIDELINES) EPINEPHRINE CATECHOLAMINES CARDIOGENIC SHOCK NOREPINEPHRINE > DOPAMINE CATECHOLAMINES CHF WITH OLIGURIA DOPAMINE CATECHOLAMINES ACUTE CHF DOBUTAMINE CATECHOLAMINES STRESS ECHO DOBUTAMINE CATECHOLAMINES NEUROGENIC HYPOTENSION DROXIDOPA CATECHOLAMINES PRIAPISM PHENYLEPHRINE (Intracavernosal) α1 AGONIST ACUTE POSTURAL HYPOTENSION MIDODRINE α1 AGONIST AUTONOMIC NERVOUS SYSTEM Compiled by Dr. Bhargav Shreeram G.
  • 2. DRUGS OF CHOICE LONG TERM POSTURAL HYPOTENSION FLUDROCORTISONE CORTICOSTEROIDS HYPERTENSIVE URGENCY CLONIDINE α2 AGONIST TICS WITH TOURETTE SYNDROME CLONIDINE α2 AGONIST PREGNANCY INDUCED HYPERTENSION LABETALOL β BLOCKER HYPOTENSION WITH SPINAL ANESTHESIA EPHEDRINE INDIRECT SYMPATHOMIMETIC ADHD METHYLPHENIDATE INDIRECT SYMPATHOMIMETIC ADHD WITH TOURETTE SYNDROME ATOMOXETINE INDIRECT SYMPATHOMIMETIC ADHD WITH FAMILY H/O DRUG ABUSE ATOMOXETINE INDIRECT SYMPATHOMIMETIC NARCOLEPSY MODAFINIL CLONIDINE WITHDRAWAL HYPERTENSION PHENTOLAMINE NON SELECTIVE α BLOCKER CHEESE REACTION PHENTOLAMINE NON SELECTIVE α BLOCKER INTRAOPERATIVE HYPERTENSION IN PHEOCHROMOCYTOMA PHENTOLAMINE NON SELECTIVE α BLOCKER PREOPERATIVE HYPERTENSION IN PHEOCHROMOCYTOMA PHENOXYBENZAMINE NON SELECTIVE α BLOCKER BENIGN PROSTATIC HYPERPLASIA ALFUZOSIN α1a BLOCKER BPH WITH HYPERTENSION DOXAZOSIN α1 BLOCKER HYPERTENSION WITH DYSLIPIDEMIA DOXAZOSIN α1 BLOCKER SCORPION BITE PRAZOSIN α1 BLOCKER HYPERTENSION WITH ANXIETY PROPRANOLOL β BLOCKER HYPERTENSION WITH HYPERTHYROIDISM PROPRANOLOL β BLOCKER HYPERTENSION WITH MIGRAINE PROPRANOLOL β BLOCKER HYPERTENSION WITH H/o MI PROPRANOLOL β BLOCKER HYPERTENSION WITH CHRONIC CHF PROPRANOLOL β BLOCKER HYPERTENSION WITH STABLE ANGINA PROPRANOLOL β BLOCKER PROPHYLAXIS OF MIGRAINE PROPRANOLOL β BLOCKER STABLE ANGINA PROPRANOLOL β BLOCKER PROPHYLAXIS OF STABLE ANGINA PROPRANOLOL β BLOCKER AORTIC DISSECTION PROPRANOLOL β BLOCKER HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY PROPRANOLOL β BLOCKER PROPHYLAXIS OF ACUTE VARICEAL BLEED PROPRANOLOL β BLOCKER ULCERATED INFANTILE HEMANGIOMA PROPRANOLOL β BLOCKER ESSENTIAL TREMOR PROPRANOLOL β BLOCKER BETA BLOCKER POISONING GLUCAGON Compiled by Dr. Bhargav Shreeram G.
  • 3. DRUGS OF CHOICE OPEN ANGLE GLAUCOMA LATANOPROST PGF2α ANALOGUE NORMAL TENSION GLAUCOMA LATANOPROST PGF2α ANALOGUE ACUTE CONGESTIVE GLAUCOMA ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR CYCLOPLEGIA - ADULTS TROPICAMIDE ANTI MUSCARINIC CYCLOPLEGIA - CHILDREN ATROPINE ANTI MUSCARINIC FAMILIAL HYPERKALEMIC PERIODIC PARALYSIS DICHLORPHENAMIDE CARBONIC ANHYDRASE INHIBITOR INCREASED ICP HEADACHE (PSEUDOTUMOR CEREBRI) ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR MOUNTAIN SICKNESS ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR MORNING SICKNESS DOXYLAMINE ANTI HISTAMINIC HAY FEVER (ALLERGIC RHINITIS) CORTICOSTEROIDS URTICARIA SECOND GENERATION ANTI HISTAMINICS ACUTE ATTACK OF MIGRAINE SUMATRIPTAN 5HT 1B/1D AGONIST CLUSTER HEADACHE SUMATRIPTAN 5HT 1B/1D AGONIST PROPHYLAXIS OF CLUSTER HEADACHE VERAPAMIL CALCIUM CHANNEL BLOCKER HEREDITARY ANGIOEDEMA - TREATMENT C1 ESTERASE INHIBITOR HEREDITARY ANGIOEDEMA - PROPHYLAXIS DANAZOL TESTOSTERONE ANALOGUE HEREDITARY TREATMENT PROPHYLAXIS - PRIOR TO SURGERY € AMINO CAPROIC ACID ANTI FIBRINOLYTICS CERVICAL RIPENING DINOPROSTONE PGE2 ANALOGUE PARACETAMOL POISONING N ACETYLCYSTEINE NIACIN INDUCED FLUSHING ASPIRIN NON-SELECTIVE COX INHIBITOR ACUTE GOUT INDOMETHACIN NON-SELECTIVE COX INHIBITOR BARTTER SYNDROME INDOMETHACIN NON-SELECTIVE COX INHIBITOR PAROXYSMAL HEMICRANIA INDOMETHACIN NON-SELECTIVE COX INHIBITOR CLOSURE OF PATENT DUCTUS ARTERIOSUS IBUPROFEN NON-SELECTIVE COX INHIBITOR FAMILIAL MEDITERRANEAN FEVER COLCHICINE MICROTUBULE INHIBITOR CHRONIC GOUT ALLOPURINOL XANTHINE OXIDASE INHIBITOR TUMOR LYSIS SYNDROME PROPHYLAXIS ALLOPURINOL XANTHINE OXIDASE INHIBITOR AUTOCOIDS CARDIOVASCULAR SYSTEM Compiled by Dr. Bhargav Shreeram G.
  • 4. DRUGS OF CHOICE ACUTE ATTACK OF SVT/PSVT ADENOSINE PROPHYLAXIS OF SVT/PSVT PROPRANOLOL β BLOCKER WPW SYNDROME WITH ATRIAL FIBRILLATION PROCAINAMIDE CLASS 1A ANTI ARRHYTHMIC WPW SYNDROME RF ABLATION > FLECAINIDE CLASS 1C ANTI ARRHYTHMIC DIGOXIN INDUCED VT / V. FIBRILLATION LIDOCAINE CLASS 1B ANTI ARRHYTHMIC MI INDUCED VT / V. FIBRILLATION LIDOCAINE CLASS 1B ANTI ARRHYTHMIC IDIOPATHIC VT PROPRANOLOL β BLOCKER VENTRICULAR PREMATURE BEATS PROPRANOLOL β BLOCKER RATE CONTROL IN ATRIAL FIBRILLATION - STABLE PT METOPROLOL β BLOCKER RATE CONTROL IN ATRIAL FIBRILLATION - UNSTABLE PT ESMOLOL β BLOCKER RHYTHM CONTROL IN ATRIAL FIBILLATION/FLUTTER AMIODARONE CLASS 3 ANTI ARRHYTHMIC ANTI ARRHYTHMIC OF CHOICE IN ACLS PROTOCOL AMIODARONE CLASS 3 ANTI ARRHYTHMIC VENTRICULAR TACHYCARDIA AMIODARONE CLASS 3 ANTI ARRHYTHMIC VENTRICULAR FIBRILLATION AMIODARONE CLASS 3 ANTI ARRHYTHMIC ACUTE ATTACK OF ATRIAL FIB / ATRIAL FLUTTER DC CARDIOVERSION PSVT WITH BRONCHIAL ASTHMA VERAPAMIL CLASS 4 ANTI ARRHYTHMIC PSVT WITH COPD VERAPAMIL CLASS 4 ANTI ARRHYTHMIC LONG QT SYNDROME - PROPHYLAXIS PROPRANOLOL β BLOCKER LONG QT SYNDROME - ACUTE ATTACK MAGNESIUM SULPHATE BRADYARRHYTHMIA d/t IWMI ATROPINE ANTI MUSCARINIC BRADYARRHYTHMIA d/t SINUS ARREST ATROPINE ANTI MUSCARINIC ACUTE CHF WITH PULMONARY EDEMA FUROSEMIDE DIURETIC RIGHT SIDED HEART FAILURE MILRINONE PDE 3 INHIBITOR RAYNAUD'S DISEASE VERAPAMIL CALCIUM CHANNEL BLOCKER HYPERTENSIVE EMERGENCY i.v. NICARDIPINE CALCIUM CHANNEL BLOCKER HYPERTENSIVE EMERGENCY IN PREGNANCY i.v. LABETOLOL β BLOCKER INSULINOMA DIAZOXIDE POTASSIUM CHANNEL OPENER ACUTE ATTACK OF ANGINA sl. NITROGLYCERIN VENODILATOR PROPHYLAXIS OF ANGINA PAIN IN MI sl. NITROGLYCERIN VENODILATOR CYANIDE POISONING AMYL NITRITE VENODILATOR MALIGNANT HYPERTENSION SODIUM NITROPRUSSIDE MIXED VASODILATOR HYPERTENSION WITH DM ACEI / ARB HYPERTENSION WITH CKD ACEI / ARB Compiled by Dr. Bhargav Shreeram G.
  • 5. DRUGS OF CHOICE HYPERTENSION WITH NEPHROTIC SYNDROME ACEI / ARB HYPERTENSION WITH SCLERODERMA ACEI / ARB HYPERTENSION WITH BILATERAL RENAL STENOSIS CALCIUM CHANNEL BLOCKER HYPERTENSION - YOUNG PATIENT ACEI / ARB HYPERTENSION - OLD PATIENT CALCIUM CHANNEL BLOCKER HYPERTENSION WITH OSTEOPOROSIS CHLORTHALIDONE THIAZIDES RESISTANT HYPERTENSION SPIRONOLACTONE ALDOSTERONE ANTAGONIST RESISTANT EDEMA SPIRONOLACTONE ALDOSTERONE ANTAGONIST CIRRHOTIC EDEMA SPIRONOLACTONE ALDOSTERONE ANTAGONIST CEREBRAL EDEMA MANNITOL OSMOTIC DIURETICS PULMONARY EDEMA FUROSEMIDE LOOP DIURETICS TYPE II HYPERLIPOPROTEINEMIA STATINS TYPE II HYPERLIPOPROTEINEMIA IN PREGNANCY / CHILDREN BILE ACID BINDING RESINS HYPERCHYLOMICRONEMIA TYPE I HYPERLIPOPROTEINEMIA FIBRATES TYPE III HYPERLIPOPROTEINEMIA FIBRATES HYPERTRIGLYCERIDEMIA / TYPE IV HYPERLIPOPROTEINEMIA FIBRATES DIABETIC KETOACIDOSIS REGULAR INSULIN TYPE 2 DIABETES MELLITUS METFORMIN BIGUANIDES ACROMEGALY OCTREOTIDE SOMATOSTATIN ANALOGUE ACUTE VARICEAL BLEED OCTREOTIDE SOMATOSTATIN ANALOGUE SECRETORY DIARRHOEA (HIV/TUMOR/CHEMOTHERAPY) OCTREOTIDE SOMATOSTATIN ANALOGUE GLUCAGONOMA OCTREOTIDE SOMATOSTATIN ANALOGUE VIPOMA OCTREOTIDE SOMATOSTATIN ANALOGUE SOMATOSTATINOMA OCTREOTIDE SOMATOSTATIN ANALOGUE CARCINOID SYNDROME OCTREOTIDE SOMATOSTATIN ANALOGUE PROSTATE CANCER Continous Dosage of GOSERELIN + FLUTAMIDE GnRH AGONIST + ANDROGEN RECEPTOR ANTAGONIST RIEDELS THYROIDITIS TAMOXIFEN SERM ENDOCRINE SYSTEM Compiled by Dr. Bhargav Shreeram G.
  • 6. DRUGS OF CHOICE ER +VE BREAST CANCER IN PRE MENOPAUSAL WOMEN TAMOXIFEN SERM ER +VE BREAST CANCER IN POST MENOPAUSAL WOMEN LETROZOLE AROMATASE INHIBITOR ANDROGENIC ALOPECIA FINASTERIDE 5α REDUCTASE INHIBITOR HYPERTHYROIDISM METHIMAZOLE THYROID PEROXIDASE INHIBITOR HYPERTHYROIDISM IN PREGNANCY (2nd & 3rd TRIMESTER) METHIMAZOLE THYROID PEROXIDASE INHIBITOR HYPERTHYROIDISM IN PREGNANCY (1st TRIMESTER) PROPYL THIOURACIL THYROID PEROXIDASE INHIBITOR SEVERE THYROTOXICOSIS / THYROID STORM PROPYL THIOURACIL THYROID PEROXIDASE INHIBITOR HYPOTHYROIDISM LEVOTHYROXINE SODIUM SALT OF T4 SUBACUTE / DEQUERVAIN THYROIDITIS ASPIRIN NON-SELECTIVE COX INHIBITOR CONGENITAL ADRENAL HYPERPLASIA (CAH) HYDROCORTISONE CORTICOSTEROIDS ANTENATAL PROPHYLAXIS OF CAH DEXAMETHASONE CORTICOSTEROIDS PRIMARY ADDISON'S DISEASE HYDROCORTISONE + FLUDROCORTISONE CORTICOSTEROIDS SECONDARY ADDISON'S DISEASE HYDROCORTISONE CORTICOSTEROIDS OSTEOPOROSIS ZOLENDRONATE BISPHOSPHONATES HYPERCALCEMIA OF MALIGNANCY ZOLENDRONATE BISPHOSPHONATES PAGETS DISEASE ZOLENDRONATE BISPHOSPHONATES POST PARTUM HEMORRHAGE OXYTOCIN GENERALIZED TONIC CLONIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER MYOCLONIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER ATONIC / AKINETIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER ABSENCE SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER LENNOUX GASTAUT SYNDROME SODIUM VALPROATE CALCIUM CHANNEL BLOCKER DRAVET SYNDROME SODIUM VALPROATE CALCIUM CHANNEL BLOCKER RAPID CYCLERS IN BIPOLAR DISORDER SODIUM VALPROATE CALCIUM CHANNEL BLOCKER REFRACTORY INTRACTABLE RHEUMATIC CHOREA SODIUM VALPROATE CALCIUM CHANNEL BLOCKER ABSENCE SEIZURES IN CHILDREN < 2 YRS ETHOSUXIMIDE CALCIUM CHANNEL BLOCKER PARTIAL SEIZURE CARBAMAZEPINE SODIUM CHANNEL BLOCKER ROLANDIC EPILEPSY CARBAMAZEPINE SODIUM CHANNEL BLOCKER GLOSSOPHARYNGEAL NEURALGIA CARBAMAZEPINE SODIUM CHANNEL BLOCKER TRIGEMINAL NEURALGIA (TIC DOLOUREX) CARBAMAZEPINE SODIUM CHANNEL BLOCKER CENTRAL NERVOUS SYSTEM Compiled by Dr. Bhargav Shreeram G.
  • 7. DRUGS OF CHOICE JME IN PREGNANCY LAMOTRIGENE SODIUM CHANNEL BLOCKER INFANTILE SPASMS WITH TUBEROUS SCLEROSIS VIGABATRIN GABA TRANSAMINASE BLOCKERS INFANTILE SPASMS WITHOUT TUBEROUS SCLEROSIS ACTH > STEROIDS FEBRILE SEIZURES p.r. DIAZEPAM BENZODIAZEPINES STATUS EPILEPTICUS i.v. LORAZEPAM BENZODIAZEPINES STATUS EPILEPTICUS IN PREGNANCY THIOPENTONE SODIUM BARBITURATES ALCOHOL WITHDRAWAL CHLORDIAZEPOXIDE BENZODIAZEPINES ALCOHOL DEPENDENCE CHLORDIAZEPOXIDE BENZODIAZEPINES HICCUPS CHLORPROMAZINE PHENOTHIAZINE CATATONIA LORAZEPAM BENZODIAZEPINES JET LAG ZOLEPLON Z COMPOUNDS INSOMNIA (SLEEP INDUCTION) ZOLEPLON Z COMPOUNDS INSOMNIA (SLEEP MAINTENANCE) ESZOPICLONE Z COMPOUNDS NEONATAL SEIZURES PHENOBARBITOL BARBITURATES CRIGLER NAJJAR SYNDROME PHENOBARBITOL BARBITURATES POST OPERATIVE CHILLS MEPERIDINE / PETHIDINE OPIOD AGONISTS BENZODIAZEPINE / Z COMPOUND TOXICITY FLUMAZENIL OPIOD TOXICITY NALOXONE OPIOD ANTAGONIST OPIOD DEPENDANCE (RELAPSE PREVENTION) NALTREXONE OPIOD ANTAGONIST MANIA PROPHYLAXIS LITHIUM BIPOLAR DISEASE PROPHYLAXIS LITHIUM HYPNIC HEADACHE LITHIUM LITHIUM INDUCED DIABETES INSIPIDUS AMILORIDE EPITHELIAL SODIUM CHANNEL BLOCKER CENTRAL DIABETES INSIPIDUS DESMOPRESSIN VASOPRESSIN ANALOGUE NOCTURNAL ENURESIS DESMOPRESSIN VASOPRESSIN ANALOGUE SIADH REDUCE FREE WATER INTAKE > TOLVAPTAN SELECTIVE V2 RECEPTOR BLOCKER NEUROPATHIC PAIN AMITRIPTYLINE TRICYCLIC ANTI DEPRESSANT POST HERPETIC NEURALGIA AMITRIPTYLINE TRICYCLIC ANTI DEPRESSANT DEPRESSION FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR PRE MENSTRUAL SYNDROME FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR OBSESSIVE COMPULSIVE DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR PHOBIAS FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR POST TRAUMATIC STRESS DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR Compiled by Dr. Bhargav Shreeram G.
  • 8. DRUGS OF CHOICE SOCIAL ANXIETY FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR GENERALIZED ANXIETY DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR BULIMIA NERVOSA FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR ANOREXIA NERVOSA FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR DEPRESSION WITH INSOMNIA MIRTAZAPINE NOR ADRENERGIC & SERATONERGIC ALZHEIMERS DISEASE RIVASTIGMINE/GALANTAMINE CHOLINERGICS SEVERE ALZHEIMERS DISEASE DONEPEZIL CHOLINERGICS PARKINSON'S DISEASE LEVODOPA DOPAMINE PRECURSOR PARKINSON'S - NON SEVERE / NON INTERFERING SELEGILINE MAO-B INHIBITORS PARKINSON'S - SEVERE / INTERFERING (<65 YRS) PRAMIPEXOLE DOPAMINE AGONIST PARKINSON'S - SEVERE / INTERFERING (>65 YRS) LEVODOPA DOPAMINE PRECURSOR PARKINSONS DISEASE - ON PERIOD - PROLONGATION ENTECAPONE COMT INHIBITORS PARKINSONS DISEASE - OFF PERIOD - RESCUE APOMORPHINE DRUG INDUCED PARKINSONS DISEASE TRIHEXYPHENIDYL (BENZHEXOL) ANTI MUSCARINIC HYPERPROLACTINEMIA CABERGOLINE DOPAMINE AGONIST HYPERPROLACTINEMIA IN PREGNANCY BROMOCRIPTINE DOPAMINE AGONIST HYPERPROLACTINEMIA IN INFERTILITY / OBESITY BROMOCRIPTINE DOPAMINE AGONIST RESTLESS LEG SYNDROME ROPINIROLE DOPAMINE AGONIST ACUTE DYSTONIA BENZTROPINE ANTI MUSCARINIC AKATHISIA PROPRANOLOL β BLOCKER NEUROLEPTIC MALIGNANT SYNDROME DANTROLENE RESISTANT SCHIZOPHRENIA CLOZAPINE ATYPICAL ANTIPSYCHOTICS SUICIDAL TENDENCY ECT > CLOZAPINE ATYPICAL ANTIPSYCHOTICS SCHIZOPHRENIA ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS ACUTE ATTACK OF MANIA ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS MANIA IN PREGNANCY ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS LEVODOPA INDUCED PSYCHOSIS QUETIAPINE ATYPICAL ANTIPSYCHOTICS RELAPSING REMITTING MULTIPLE SCLEROSIS INTERFERON β PROGRESSIVE RELAPSING MULTIPLE SCLEROSIS MITOXANTRONE ACUTE ATTACK OF MULTIPLE SCLEROSIS METHYL PREDNISOLONE CORTICOSTEROIDS BELL'S PALSY PREDNISOLONE CORTICOSTEROIDS Compiled by Dr. Bhargav Shreeram G.
  • 9. DRUGS OF CHOICE ACUTE ATTACK OF BRONCHIAL ASTHMA LOW DOSE FLUTICASONE + FORMOTEROL ICS + LABA COPD TIOTROPIUM/UMECLIDINIUM ANTI MUSCARINIC PERSISTENT BRONCHIAL ASTHMA FLUTICASONE + FORMOTEROL ICS + LABA LONGTERM FOR EXERCISE INDUCED ASTHMA FLUTICASONE INHALATIONAL CORTICOSTEROIDS PULMONARY HYPERTENSION STAGE II/III BOSENTAN ENDOTHELIN ANTAGONIST PULMONARY HYPERTENSION STAGE IV EPOPROSTERENOL PGI2 ANALOGUE RECURRENT APNEA OF PREMATURITY CAFFEINE METHYLXANTHINES ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS (ABPA) PREDNISOLONE CORTICOSTEROIDS PROLIFERATIVE BRONCHIOLITIS PREDNISOLONE CORTICOSTEROIDS CRYPTOGENIC ORGANIZING PNEUMONIA / BRONCHIOLITIS OBLITERANS ORGANISING PNEUMONIA PREDNISOLONE CORTICOSTEROIDS EOSINOPHILIC PNEUMONIA PREDNISOLONE CORTICOSTEROIDS SARCOIDOSIS PREDNISOLONE CORTICOSTEROIDS ANEMIA d/t CHEMOTHERAPY ERYTHROPOIETIN ANALOGUE ANEMIA d/t CHRONIC RENAL FAILURE ERYTHROPOIETIN ANALOGUE ANEMIA d/t ZIDOVUDINE ERYTHROPOIETIN ANALOGUE ANEMIA d/t DIALYSIS ERYTHROPOIETIN ANALOGUE NEUTROPENIA d/t CHEMOTHERAPY FILGRASTIM GRANULOCYTE - CSF NEUTROPENIA d/t HIV FILGRASTIM GRANULOCYTE - CSF THROMBOPROPHYLAXIS IN NON VALVULAR ATRIAL FIBRILLATION DABIGATRAN + EDOXABAN DIRECT ORAL ANTICOAGULANTS THROMBOPROPHYLAXIS AFTER ELECTIVE HIP/KNEE ARTHROPLASTY RIVAROXABAN FACTOR Xa INHIBITOR HEPARIN INDUCED THROMBOCYTOPENIA ARGATROBAN DIRECT THROMBIN INHIBITOR CATHETER INDUCED THROMBOSIS UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR THROMBOSIS IN CARDIOPULMONARY BYPASS UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR CONCURRENT THROMBOLYSIS WITH INCREASED RISK OF BLEEDING UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR THROMBOSIS IN MI LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR RESPIRATORY SYSTEM HEMATOLOGY Compiled by Dr. Bhargav Shreeram G.
  • 10. DRUGS OF CHOICE THROMBOSIS IN UNSTABLE ANGINA LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR DEEP VEIN THROMBOSIS LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR PULMONARY EMBOLISM LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR CANCER INDUCED THROMBOSIS LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR PROPHYLAXIS OF THROMBOSIS IN VALVULAR ATRIAL FIBRILLATION WARFARIN PROPHYLAXIS OF DEEP VENOUS THROMBOSIS WARFARIN PROPHYLAXIS OF PULMONARY EMBOLISM WARFARIN PROPHYLAXIS OF THROMBOSIS d/t MECHANICAL VALVE DURING PREGNANCY WARFARIN ANTI PHOSPHOLIPID ANTIBODY SYNDROME WARFARIN ANTI PHOSPHOLIPID ANTIBODY SYNDROME IN PREGNANCY ASPIRIN + (LMWH> UFH) THROMBOLYSIS INDUCED BLEEDING € AMINO CAPROIC ACID PEPTIC ULCER DISEASE OMEPRAZOLE PROTON PUMP INHIBITIOR NSAID INDUCED ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR STRESS ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR GERD OMEPRAZOLE PROTON PUMP INHIBITIOR ZOLLINGER ELLISON SYNDROME OMEPRAZOLE PROTON PUMP INHIBITIOR H.PYLORI ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR GERD IN PREGNANCY/ CHILDREN ANTACIDS PROPHYLAXIS OF ASPIRATION PNEUMONIA IN POST OP PTS RANITIDINE H2 BLOCKERS CHEMOTHERAPY INDUCED NAUSEA & VOMITING - EARLY ONSET ONDANSETRON 5HT3 RECEPTOR BLOCKERS CHEMOTHERAPY INDUCED NAUSEA & VOMITING - LATE ONSET APREPITANT NK1 RECEPTOR ANTAGONISTS IBS WITH CONSTIPATION POLYETHYLENE GLYCOL IBS WITH VISCERAL PAIN TRICYCLIC ANTIDEPRESSANTS IBS WITH DIARRHOEA LOPERAMIDE OPIOD AGONISTS GASTROINTESTINAL SYSTEM Compiled by Dr. Bhargav Shreeram G.
  • 11. DRUGS OF CHOICE NON SECRETORY DIARRHOEA LOPERAMIDE OPIOD AGONISTS ULCERATIVE COLITIS - MILD / MODERATE MESALAMINE 5 ASA ANALOGUE ULCERATIVE COLITIS - SEVERE BUDESONIDE CORTICOSTEROIDS ULCERATIVE COLITIS - STEROID DEPENDANT AZATHIOPRINE PURINE SYNTHESIS INHIBITORS ULCERATIVE COLITIS - STEROID RESISTANT CYCLOSPORINE CALCINEURIN INHIBITORS PROPHYLAXIS OF ULCERATIVE COLITIS MESALAMINE 5 ASA ANALOGUE CROHN'S DISEASE - MILD / MODERATE PREDNISOLONE CORTICOSTEROIDS CROHN'S DISEASE - SEVERE (WITH FISTULA) INFLIXIMAB ANTI TNF-α PROPHYLAXIS OF CROHN'S DISEASE INFLIXIMAB ANTI TNF-α HEMOCHROMATOSIS DEFEROXAMINE IRON CHELATOR NEPHROTIC SYNDROME GLUCOCORTICOIDS STEROIDS STEROID DEPENDANT NEPHROTIC SYNDROME CYCLOPHOSPHAMIDE NITROGEN MUSTARDS STEROID RESISTANT NEPHROTIC SYNDROME CYCLOSPORINE CALCINEURIN INHIBITORS LUPUS NEPHRITIS CYCLOPHOSPHAMIDE + GLUCORTICOIDS NITROGEN MUSTARDS + STEROIDS CYSTINURIA TIOPRONIN + POTASSIUM CITRATE CYSTEINE BINDER + URINE ALKALINIZER MRSA (STAPHYLOCOCCAL ENDOCARDITIS) VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS PSEUDOMEMBRANOUS ENTEROCOLITIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS PNEUMOCOCCAL MENINGITIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS ENTEROCOCCUS FAECIUM VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS ENTEROCOCCUS FAECALIS AMPICILLIN AMINOPENICILLINS AMPICILLIN RESISTANT ENTEROCOCCUS FAECALIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS LISTERIA AMPICILLIN AMINOPENICILLINS HEMOPHILUS INFLUENZAE - PNEUMONIA/OTITIS MEDIA AMPICILLIN AMINOPENICILLINS STREPTOCOCCAL ENDOCARDITIS AMPICILLIN AMINOPENICILLINS ENTEROCOCCAL ENDOCARDITIS AMPICILLIN AMINOPENICILLINS VRSA DAPTOMYCIN LIPOPEPTIDES EMPERICAL MRSA DAPTOMYCIN LIPOPEPTIDES SYPHILIS - ALL STAGES BENZATHINE PENICILLIN G NARROW SPECTRUM PENICILLINS ANTIMICROBIALS RENAL SYSTEM Compiled by Dr. Bhargav Shreeram G.
  • 12. DRUGS OF CHOICE SYPHILIS - CNS STAGES AQUEOUS PENICILLIN G NARROW SPECTRUM PENICILLINS STREPTOCOCCUS PENICILLIN G NARROW SPECTRUM PENICILLINS YAWS PENICILLIN G NARROW SPECTRUM PENICILLINS ACTINOMYCOSIS PENICILLIN G NARROW SPECTRUM PENICILLINS LEPTOSPIROSIS PENICILLIN G NARROW SPECTRUM PENICILLINS GAS GANGRENE PENICILLIN G NARROW SPECTRUM PENICILLINS RAT BITE FEVER PENICILLIN G NARROW SPECTRUM PENICILLINS MASTITIS CLOXACILLIN PENICILLINASE RESISTANT PENICILLINS SURGICAL PROPHYLAXIS CEPHAZOLIN 1st GENERATION CEPHALOSPORINS GONORRHOEA CEFTRIAXONE + AZITHROMYCIN 3rd GENERATION CEPHALOSPORINS CEFTRIAXONE RESISTANT GONORRHOEA SPECTINOMYCIN AMINOGLYCOSIDES E. COLI CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS KLEBSIELLA CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS PROVIDENCIA CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS EMPIRICAL OSTEOMYELITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS EMPERICAL MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS HEMOPHILUS INFLUENZA MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS MENINGOCOCCAL MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS TYPHOID CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS TYPHOID (ORAL DOC) CEFIXIME 3rd GENERATION CEPHALOSPORINS PSEUDOMONAS CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS MELIOIDOSIS / BURKHOLDERIA CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS FEBRILE NEUTROPENIA CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS ESBL PRODUCING ORGANISMS IMIPENEM CARBAPENEMS SERRATIA IMIPENEM CARBAPENEMS ENTEROBACTER IMIPENEM CARBAPENEMS ACINETOBACTER IMIPENEM CARBAPENEMS VRSA PNEUMONIA LINEZOLID OXAZOLIDINONE VRE LINEZOLID OXAZOLIDINONE MYCOPLASMA HOMINIS - STD DOXYCYCLINE TETRACYCLINES UREAPLASMA - STD DOXYCYCLINE TETRACYCLINES PROPHYLAXIS OF PLAGUE DOXYCYCLINE TETRACYCLINES RICKETTSIA DOXYCYCLINE TETRACYCLINES Compiled by Dr. Bhargav Shreeram G.
  • 13. DRUGS OF CHOICE BRUCELLA DOXYCYCLINE TETRACYCLINES BORELLIA DOXYCYCLINE TETRACYCLINES CHLAMYDIA (LGV) DOXYCYCLINE TETRACYCLINES CHOLERA DOXYCYCLINE TETRACYCLINES BARTONELLA DOXYCYCLINE TETRACYCLINES PLEURODESIS DOXYCYCLINE TETRACYCLINES PERICARDIODESIS DOXYCYCLINE TETRACYCLINES PLAGUE GENTAMICIN AMINOGLYCOSIDES TULAREMIA GENTAMICIN AMINOGLYCOSIDES GUT STERILIZATION IN HEPATIC ENCEPHALOPATHY RIFAMIXIN DIPHTHERIA ERYTHROMYCIN MACROLIDES PERTUSSIS ERYTHROMYCIN MACROLIDES PROPHYLAXIS OF RHEUMATIC FEVER IN PENICILLIN ALLERGY ERYTHROMYCIN MACROLIDES ATYPICAL PNEUMONIA (MYCOPLASMA, CHLAMYDIA, LEGIONELLA) AZITHROMYCIN MACROLIDES CAMPYLOBACTER AZITHROMYCIN MACROLIDES CHANCROID AZITHROMYCIN MACROLIDES CHLAMYDIA AZITHROMYCIN MACROLIDES GRANULOMA INGUINALE AZITHROMYCIN MACROLIDES CHOLERA IN PREGNANCY / CHILDREN AZITHROMYCIN MACROLIDES TOXIC SHOCK SYNDROME CLINDAMYCIN + VANCOMYCIN ANAEROBIC INFECTION - SUPRADIAPHRAGMATIC (PREVOTELLA) CLINDAMYCIN LINCOSAMIDE ANTIBIOTICS STAPHYLOCOCCUS NASAL CARRIER Topical MUPIROCIN SHIGELLA CIPROFLOXACIN FLUOROQUINOLONES TRAVELLER'S DIARRHOEA CIPROFLOXACIN FLUOROQUINOLONES PYELONEPHRITIS CIPROFLOXACIN FLUOROQUINOLONES MENINGOCOCCAL CONTACTS / MASS PROPHYLAXIS CIPROFLOXACIN FLUOROQUINOLONES ANTHRAX CIPROFLOXACIN FLUOROQUINOLONES TYPHOID CARRIERS CIPROFLOXACIN FLUOROQUINOLONES PNEUMOCYSTIS COTRIMOXAZOLE SULFONAMIDES PROPHYLAXIS OF PNEUMOCYSTIS COTRIMOXAZOLE SULFONAMIDES Compiled by Dr. Bhargav Shreeram G.
  • 14. DRUGS OF CHOICE NOCARDIOSIS COTRIMOXAZOLE SULFONAMIDES ISOSPORIASIS COTRIMOXAZOLE SULFONAMIDES CYCLOSPORIASIS COTRIMOXAZOLE SULFONAMIDES SARCOCYSTOSIS COTRIMOXAZOLE SULFONAMIDES CYSTITIS COTRIMOXAZOLE SULFONAMIDES PROSTATITIS COTRIMOXAZOLE SULFONAMIDES TOXOPLASMA SULFADIAZINE + PYRIMETHAMINE SULFONAMIDES TOXOPLASMA IN PREGNANCY SPIRAMYCIN MACROLIDES BURNS PATIENT TOPICAL SULFADIAZINE SULFONAMIDES PROPHYLAXIS OF TB (PT WITH HIV WITH LATENT INFECTION) ISONIAZID ISONIAZID INDUCED SEIZURES PYRIDOXINE DERMATITIS HERPETIFORMIS DAPSONE HERPES SIMPLEX VIRUS VALACYCLOVIR > ACYCLOVIR GUANINE ANALOGUES VARICELLA ZOSTER VIRUS VALACYCLOVIR > ACYCLOVIR GUANINE ANALOGUES CYTOMEGALOVIRUS VALAGANCYCLOVIR > GANCYCLOVIR GUANINE ANALOGUES RECURRENT LARYNGEAL PAPILLOMATOSIS CIDOFOVIR CYTIDINE ANALOGUES RESISTANT HERPES FOSCARNET GENITAL WARTS (HPV) - MALE PODOPHYLLIN TOXIN MICROTUBULE INHIBITOR GENITAL WARTS (HPV) - NON PREGNANT FEMALE IMIQUIMOD TLR-7 AGONIST GENITAL WARTS (HPV) - PREGNANT FEMALE CRYOTHERAPY WITH LIQUID N2 (-196) INFLUENZA - A, B OSELTAMIVIR NEURAMINIDASE INHIBITORS BIRD FLU OSELTAMIVIR NEURAMINIDASE INHIBITORS OSELTAMIVIR RESISTANT INFLUENZA A / B / BIRD FLU ZANAMIVIR NEURAMINIDASE INHIBITORS HEPATITIS - B TENOFOVIR DNA POLYMERASE INHIBITORS HEPATITIS B WITH HEPATITIS D SUPERINFECTION INTERFERON α RESPIRATORY SYNCITIAL VIRUS INHALATIONAL RIBAVIRIN PROPHYLAXIS OF RSV s.c. PALIVIZUMAB HIV - PERINATAL TRANSMISSION NEVIRAPINE MUCORMYCOSIS AMPHOTERICIN B POLYENES ANTIFUNGALS SYSTEMIC FUNGAL INFECTIONS AMPHOTERICIN B POLYENES ANTIFUNGALS KALA AZAR AMPHOTERICIN B POLYENES ANTIFUNGALS PRIMARY AMOEBIC MENINGOENCEPHALITIS AMPHOTERICIN B POLYENES ANTIFUNGALS Compiled by Dr. Bhargav Shreeram G.
  • 15. DRUGS OF CHOICE CRYPTOCOCCAL MENINGITIS i.v. AMPHOTERICIN B + i.v. FLUCYTOSINE POLYENES ANTIFUNGALS CANDIDA ALBICANS FLUCONAZOLE AZOLES COCCIDIAL MENINGITIS FLUCONAZOLE AZOLES ENDEMIC MYCOSIS ITRACONAZOLE AZOLES SPOROTRICHOSIS ITRACONAZOLE AZOLES TINEA CRURIS ITRACONAZOLE AZOLES TINEA CORPORIS ITRACONAZOLE AZOLES INVASIVE ASPERGILLOSIS VORICONAZOLE AZOLES SCEDOSPORIUM VORICONAZOLE AZOLES TRICHOSPORIUM VORICONAZOLE AZOLES PROPHYLAXIS OF INVASIVE ASPERGILLOSIS POSACONAZOLE AZOLES PROPHYLAXIS OF FUNGAL INFECTION IN GVHD POSACONAZOLE AZOLES CANDIDA GLABRATA CASPOFUNGIN ECHINOCANDINS CANDIDA KRUSEI CASPOFUNGIN ECHINOCANDINS CANDIDA PARAPSILOSIS CASPOFUNGIN ECHINOCANDINS TRICHOPHYTON TERBINAFINE MICROSPORUM GRISEOFULVIN EPIDERMOPHYTON GRISEOFULVIN T. CAPITIS (KERION/BOGGY SWELLING) GRISEOFULVIN FUNGAL CORNEAL ULCER TOPICAL NATAMYCIN ECHINOCOCCUS GRANULARIS ALBENDAZOLE BENZIMIDAZOLES ECHINOCOCCUS MULTILOCULARIS ALBENDAZOLE BENZIMIDAZOLES NEUROCYSTICERCOSIS ALBENDAZOLE BENZIMIDAZOLES LIVER FLUKE TRICLOBENDAZOLE BENZIMIDAZOLES HOOK WORM ALBENDAZOLE BENZIMIDAZOLES ROUND WORM ALBENDAZOLE BENZIMIDAZOLES WHIP WORM ALBENDAZOLE BENZIMIDAZOLES TRICHINELLA SPIRALIS ALBENDAZOLE BENZIMIDAZOLES ENTEROBIUS VERMICURALIS ALBENDAZOLE BENZIMIDAZOLES THREAD WORM (STRONGYLOIDES) IVERMECTIN ONCHOCERCA VOLVULUS IVERMECTIN SCABIES (ORAL) IVERMECTIN SCABIES Topical PERMETHRIN Compiled by Dr. Bhargav Shreeram G.
  • 16. DRUGS OF CHOICE FILARIASIS DIETHYL CARBAMAZINE LOA LOA DIETHYL CARBAMAZINE DIPHYLLOBOTHRIUM LATUM PRAZIQUANTEL HYMENOLEPIS NANA PRAZIQUANTEL TAENIA SOLIUM (INTESTINAL) PRAZIQUANTEL TAENIA SAGINATA PRAZIQUANTEL LUNG FLUKE PRAZIQUANTEL SCHISTOSOMA PRAZIQUANTEL INTESTINAL AMOEBIASIS - ASYMPTOMATIC PARAMOMYCIN INTESTINAL AMOEBIASIS - SYMPTOMATIC METRONIDAZOLE NITROIMIDAZOLE EXTRAINTESTINAL AMOEBIASIS METRONIDAZOLE NITROIMIDAZOLE TETANUS METRONIDAZOLE NITROIMIDAZOLE GIARDIASIS METRONIDAZOLE NITROIMIDAZOLE GARDNERELLA VAGINALIS METRONIDAZOLE NITROIMIDAZOLE TRICHOMONIASIS METRONIDAZOLE NITROIMIDAZOLE ANAEROBIC INFECTION - INFRADIAPHRAGMATIC (BACTEROIDES) METRONIDAZOLE NITROIMIDAZOLE DRACUNCULIASIS METRONIDAZOLE NITROIMIDAZOLE VISCERAL LEISHMANIASIS i.v. AMPHOTERICIN B POLYENES ANTIFUNGALS VISCERAL LEISHMANIASIS (ORAL) MILTEFOSINE CUTANEOUS LEISHMANIASIS SODIUM STIBOGLYCUNATE TRYPANOSOMA - EARLY EAST AFRICAN SLEEPING SICKNESS SURAMINE TRYPANOSOMA - LATE EAST AFRICAN SLEEPING SICKNESS MELARSOPROL TRYPANOSOMA - EARLY WEST AFRICAN SLEEPING SICKNESS PENTAMIDINE TRYPANOSOMA - LATE WEST AFRICAN SLEEPING SICKNESS EFLORNITHINE TRYPANOSOMA - AMERICAN (CHAGA'S DISEASE) BENZNIDAZOLE CRYPTOSPORIDIOSIS NITAZOXANIDE RESISTANT GIARDIASIS NITAZOXANIDE PLASMODIUM OVALE CHLOROQUINE + PRIMAQUINE PLASMODIUM VIVAX CHLOROQUINE + PRIMAQUINE Compiled by Dr. Bhargav Shreeram G.
  • 17. DRUGS OF CHOICE RADICAL CURE / TERMINAL PROPHYLAXIS OF RELAPSE OF PLASMODIUM VIVAX/OVALE TAFENOQUINE > PRIMAQUINE PLASMODIUM FALCIPARUM ARTESUNATE + SULFADOXINE + PYRIMETHAMINE (+ PRIMAQUINE on Day 2) CHOROQUINE RESISTANT P. OVALE/VIVAX ARTESUNATE + SULFADOXINE + PYRIMETHAMINE (+ PRIMAQUINE on Day 2) MALARIA IN NORTH EASTERN STATES ARTEMETHER + LUMEFANTRINE PLASMODIUM VIVAX IN PREGNANCY CHLOROQUINE PLASMODIUM OVALE IN PREGNANCY CHLOROQUINE SEVERE FALCIPARUM IN PREGNANCY QUININE RESISTANT MALARIA IN PREGNANCY QUININE PLASMODIUM FALCIPARUM IN PREGNANCY (1st TRIMESTER) QUININE + CLINDAMYCIN PLASMODIUM FALCIPARUM IN PREGNANCY (2nd & 3rd TRIMESTER) ARTEMETHER + LUMEFANTRINE MALARIA PROPHYLAXIS (FOR TRAVEL < 6 WKS) DOXYCYCLINE MALARIA PROPHYLAXIS (FOR TRAVEL >6 WKS/ PREGNANCY) MEFLOQUINE BABESIOSIS ATOVAQUONE + AZITHROMYCIN WEGNER'S GRANULOMATOSIS CYCLOPHOSPHAMIDE NITROGEN MUSTARDS CYCLOPHOSPHAMIDE INDUCED HEMORRHAGIC CYSTITIS MESNA BRAIN TUMORS TEMOZOLOMIDE ALKYLATING AGENTS HEAD & NECK CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS ESOPHAGEAL CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS GASTRIC CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS UROGENITAL CANCER CISPLATIN PLATINUM COMPOUNDS ALK +VE NON SMALL CELL CARCINOMA LUNG CRIZONTINIB ALK INHIBITORS MESOTHELIOMA PEMETREXED ANTI FOLATE DRUGS PANCREATIC CA GEMCITABINE PYRIMIDINE ANALOGUES HEPATOCELLULAR CARCINOMA SORAFENIB VEGF RECEPTOR INHIBITORS GASTROINTESTINAL STROMAL TUMOUR IMATINIB TYROSINE KINASE INHIBITORS ANTI CANCER DRUGS Compiled by Dr. Bhargav Shreeram G.
  • 18. DRUGS OF CHOICE CHORIOCARCINOMA METHOTREXATE ANTI FOLATE DRUGS CARCINOMATOUS MENINGITIS METHOTREXATE ANTI FOLATE DRUGS RHEUMATOID ARTHRITIS METHOTREXATE ANTI FOLATE DRUGS ERYTHRODERMIC PSORIASIS METHOTREXATE ANTI FOLATE DRUGS PSORIATIC ARTHRITIS METHOTREXATE ANTI FOLATE DRUGS CHRONIC PLAQUE PSORIASIS METHOTREXATE ANTI FOLATE DRUGS MILD PSORIASIS ACITRETIN ORAL RETINOIDS PSORIASIS IN HIV ACITRETIN ORAL RETINOIDS PUSTULAR PSORIASIS ACITRETIN ORAL RETINOIDS PUSTULAR PSORIASIS OF PREGNANCY (IMPETIGO HERPETIFORMIS) CYCLOSPORINE > ORAL STEROIDS CALCINEURIN INHIBITORS TUMOR LYSIS SYNDROME ALLOPURINOL PURINE ANALOGUES CML IMATINIB TYROSINE KINASE INHIBITORS MULTI TYROSINE KINASE RESISTANT CML OMACETAXINE HAIRY CELL LEUKEMIA CLADRIBINE PURINE ANALOGUES HISTIOCYTOSIS CLADRIBINE PURINE ANALOGUES MYELODYSPLASIA AZACITIDINE + DECITABINE PYRIMIDINE ANALOGUES MYELODYSPLASIA WITH 5q DELETION LENALIDOMIDE THALIDOMIDE DERIVATIVE ESSENTIAL THROMBOCYTHEMIA HYDROXYUREA SICKLE CELL ANAEMIA HYDROXYUREA POLYCYTHEMIA VERA ANAGRELIDE > HYDROXYUREA PROMYELOCYTIC LEUKEMIA (PML) RETINOIC ACID RETINOIC ACID RESISTANT PML ARSENIC TRIOXIDE HER 2 POSITIVE BREAST CANCER TRANZTUZUMAB / PERTUZUMAB HER 2 POSITIVE GASTRIC CANCER TRANZTUZUMAB / PERTUZUMAB RESISTANT HER 2 POSITIVE BREAST CANCER / GASTRIC CANCER LAPATINIB / NERATINIB RENAL CELL CANCER BEVACIZUMAB / SUNITINIB Compiled by Dr. Bhargav Shreeram G.