BASIC CONCEPT OF SIGNAL TRANSDUCTION

1. Presentation
on
Signal transduction
By
Biswajit Sahoo
Ph. D. 1st year
Deptt. Of Genetics and Plant Breeding

2. Introduction
 Signal- It is a type of message or information for a cell to perform a
particular function.
 External signal- the signal outside the cell.
 Internal signal- the signal inside the cell.
 Transduction- It is a process of converting message or information
from one form to another form.
 Ligands -It is a organic/inorganic molecules which alters the other
protein structure or receptor.
 Receptors-The protein to which ligands binds is called receptor.
 Signal transduction- It is defined as the transfer of signal through a
path way in the cytosol by a membrane –bound receptor in response
to binding to it of a ligand on the outside cell.

3. Signal Pathways
Receptor cells on the surface of the plasma membrane or
within the cytoplasm of the cell induce changes in the cell that
elicit appropriate responses, generally some type of chemical
reaction or series of metabolic reactions.
The three stages of cell signaling are, therefore, reception,
transduction and response.
The series of steps involved is referred to as a signal
transduction pathway and there are a variety of methods for
signaling

11. Signal transduction:-
Trimeric G-Protein disassemble to Relay signals from G-Protein
Linked Receptors:-

13. Protein phosphorylation and kinase cascade
mechanism:
The two important pathways are:
 The Ras/Raf/MAP kinase pathway, which is important in
cell division, growth and differentiation.
 The Jak/Stat pathway, which is activated by many cytokines
and which controls the synthesis and release of many
inflammatory mediators.

15. Application
 To know the plant pathogen interaction for developing
resistance variety against pathogen.
 To know abiotic stress resistance mechanism to develop
drought, alkalinity, salinity tolerant variety.
 To develop herbicide resistant variety by modifying the
pathway.

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