3. Introduction
• Guggulu is a popular herb classified as tridosha hara in
Indian Ayurvedic medicine.
• Detailed account of guggulu as a drug is given in the
treatises of Charaka (1000 B.C.),Sushruta (600 B.C.),
Vagbhata (17th century A.D.) and various Nighantus
written in India between 12th and 14th centuries.
• Guggulu always formulated with other ingredients in
formulation based concept in Ayurveda with or without
specific anupana.
• Rasnadi guggulu is explained by Yogaratnakar in
karnarogadhikara.
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10. • Guggulu is pounded in a mortar first and
pestle with ghee and gradually add fine
powders of the other five ingredients .
• 500 mg tablets are made out of the
mixture when fine semisolid mass
consistency is attained.
• Niragni guggulu vati example.
• Sagni method can also be done.
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11. • In large scale practice,
• Color become dark black and tablet are round in
shape.
• In edge runner mill most sophisticated instrument,
paste form occurs after one complete day with full
rotation.
• temperature of drying should be between 80-90
degree Celsius.
• The mixing should be done in geometry way.
• The powder put in mass mixer for 3 hours in a day
with full speed.
• After compression the drug is transfer in a tight bottle
container.
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12. Anandakanda Rasendrakhanda 20th upadesha Vatavyadhi
chikitsa
Here shuddha guggulu 5 parts , rasna 4 parts
and ghrta q.s used.
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13. • The Deepana, Amapachan and Rasayana
properties of Rasna is overall beneficial for
body systems.
• Guggulu is a drug of choice in cases of Vata
disorder because of its Vata-Kapha Shamaka
and Vedanasthapana, Rasayana properties.
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14. Indications
• Vatavyadhi- neurological disorders like paralysis,
neuropathy, joint related disorders
• Karnagada – tinnitus
• Shirogada- headache, migraine etc
• Nadiroga
• Bhagandara
[Rasnadi kwatha also used for vedana shamaka
and shothahara]
• Sandhigata vata
• Amavata
• Mainly for shamana
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15. Dose
• No adverse effects reported with 750 mg- 1 g
daily for 1 month – 3 months
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16. Anupana
• Based on the vyadhi and rogee avastha
• Ushnodaka- samanya
• Maharasnadi kashayam – shoola, sandhiroga
• Lohasavam for bhagandara
• Pathyadi kwatha – shiroroga
• Punarnavarishta- gout or
hyperuricemia.(pittarakta and shophahara?)
• Ashwagandharishta- osteoarthritis
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17. Mode of action
• Rasna an excellent anti inflammatory and pain
relieving herb along with shunti, devadaru and
eranda excellent vatahara herbs.
• Vatakaphahara
• Apana vayu correction
• Deepana, pachana - amapachaka
• Srotoshodhana-helps in healing sinus track.
• Shoolahara
• Anti- inflammatory and Analgesic properties.
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18. Research Works
• Contribution of Ayurveda in management of
Spinal Cord Injury (SCI ) induced Paraplegia by
Punam Sawarkar-Rasnadi Guggulu 2 tabs (Each
250 mg )BID with Rasnasaptak Quath as
shamana.
• Shukla, K. P. et.al.: Evaluation of Rasnadi
Guggulu compound in the treatment of
Rheumatoid arthritis,Rheumatism,1985
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19. • Evaluation of clinical efficacy of Vaitarna Basti and Rasnadi Gutika in
the management of Gridhrasi W.S.R. Sciatica Anil Gangwar, Rachana
Gupta, Alok K. Srivastava, Uttam Sharma, Kulratan Singh, Priyanka
Rani;2015.
• EFFECT OF RASNADI GUGGULU AND BILVADI TAILA IN THE
MANAGEMENT OF BADHIRYA . A-PRELMINARY STUDY; 2014.
• MANAGEMENT OF A CASE OF LUMBAR STENOSIS WITH
AYURVEDIC INTERVENTION RATHA KSHIROD KUMAR*, BARIK
LAXMI DHAR, HAZRA JAYRAM ; 2016.
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20. • Khanna D et .al. Natural products as a goldmine for
arthritis treatment,curr opin pharmacology2007;7:344-
354.
-Mukul extract exhibited anti-inflammatory activity as it
reduced paw volume induced by formalin in rats. In the
carrageen induced rat paw edema model, the 250mg /kg dose
of the formulation (rasnadi guggul) showed significant activity
(p<0.001) at the end of 5th and 4th hour respectively. It also
had an inhibitory action against the granuloma pouch test.
New terpenes Myrrhanol A and Myrrhanone A from guggul-
gum resins showed potent anti- inflammatory effect on
adjuant induced air pouch granuloma of mice.
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21. Conclusion
• Rasnadi panchaka kwatha drugs have been
modified to a guggulu formulation imparting
properties of guggulu and is user friendly.
• A formula possessing vata kapha shamaka,
vatanulomana and rasayana action in many
ama associated vatavyadhis after proper
shodhana therapies.
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