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RASNADI GUGGULU
YOGA REVIEW
Dr Anjana P
Final year pg scholar
R&B DEPARTMENT
GOVT.AYURVEDA COLLEGE TRIPUNITHURA KERALA
Contents
• Introduction
• Ingredients
• Properties
• Indications
• Dose
• Mode of action
• Conclusion
• References
28/21/2020
Introduction
• Guggulu is a popular herb classified as tridosha hara in
Indian Ayurvedic medicine.
• Detailed account of guggulu as a drug is given in the
treatises of Charaka (1000 B.C.),Sushruta (600 B.C.),
Vagbhata (17th century A.D.) and various Nighantus
written in India between 12th and 14th centuries.
• Guggulu always formulated with other ingredients in
formulation based concept in Ayurveda with or without
specific anupana.
• Rasnadi guggulu is explained by Yogaratnakar in
karnarogadhikara.
38/21/2020
Also Mentioned in
• Bhaishajya ratnavali vatavyadhi
• Brihat yoga tarangini
• Brhat nighantu ratanakara
• Anandakanda vatavyadhi chikitsa(different
formula)
48/21/2020
• Rasnaamrteranda surahva vishvatulyam
purenaatha vimrdya khaadet |
Vataamayii karnashirogadii cha
naadiyutaschaiva bhagandarii cha ||
[YOGARATNAKARA KARNAROGADHIKAARA,
BRIHATNIGHANTU RATNAKARA VATAVYADHI]
58/21/2020
Ingredients
68/21/2020
Rasna 1 part
Guduchi 1 part
Eranda 1 part
Devadaru 1 part
Shunti 1 part
Shuddha guggulu 5 parts
Goghrta Quantity sufficient
Rasna
• Pluchea lanceolata
• Tikta rasa
• Guru guna
• Ushna veerya
• Katu vipaka
• vatakaphahar
• Amapachana
Guduchi
• Tinosporacordifolia
• Tikta, Kashaya rasa
• Laghu guna
• Ushna veerya
• Madhura vipaka
• Tridoshashaghna
Balya, Dipana,
Rasayana, Sangrahi,
Raktasodhaka,
Jvaraghna8/21/2020 7
• Eranda
• Ricinus communis
• Madhura rasa
• Guru, Snigdha guna
• Ushna veerya
• Madhura vipaka
• vatakaphahara Vrushya,
amapachaka
• Devadaru
• Cedrus deodara
• Tikta rasa
• Laghu, Snigdha guna
• Ushna Veerya
• Katu vipaka
• vatakaphashamak
Kaphahara, Vatahara,
Dushtavranashodhaka
8/21/2020 8
• Shunthi
• Zingiber officinale
• Katu Rasa
• Laghu, Snigdha guna
• Ushna veerya
• Madhura vipaka
• vatakaphashamak Anulomana, Dipana, Hridya,
Pachana, Vatakaphapaha, pittalam.
8/21/2020 9
• Guggulu is pounded in a mortar first and
pestle with ghee and gradually add fine
powders of the other five ingredients .
• 500 mg tablets are made out of the
mixture when fine semisolid mass
consistency is attained.
• Niragni guggulu vati example.
• Sagni method can also be done.
108/21/2020
• In large scale practice,
• Color become dark black and tablet are round in
shape.
• In edge runner mill most sophisticated instrument,
paste form occurs after one complete day with full
rotation.
• temperature of drying should be between 80-90
degree Celsius.
• The mixing should be done in geometry way.
• The powder put in mass mixer for 3 hours in a day
with full speed.
• After compression the drug is transfer in a tight bottle
container.
8/21/2020 11
Anandakanda Rasendrakhanda 20th upadesha Vatavyadhi
chikitsa
Here shuddha guggulu 5 parts , rasna 4 parts
and ghrta q.s used.
128/21/2020
• The Deepana, Amapachan and Rasayana
properties of Rasna is overall beneficial for
body systems.
• Guggulu is a drug of choice in cases of Vata
disorder because of its Vata-Kapha Shamaka
and Vedanasthapana, Rasayana properties.
8/21/2020 13
Indications
• Vatavyadhi- neurological disorders like paralysis,
neuropathy, joint related disorders
• Karnagada – tinnitus
• Shirogada- headache, migraine etc
• Nadiroga
• Bhagandara
[Rasnadi kwatha also used for vedana shamaka
and shothahara]
• Sandhigata vata
• Amavata
• Mainly for shamana
148/21/2020
Dose
• No adverse effects reported with 750 mg- 1 g
daily for 1 month – 3 months
158/21/2020
Anupana
• Based on the vyadhi and rogee avastha
• Ushnodaka- samanya
• Maharasnadi kashayam – shoola, sandhiroga
• Lohasavam for bhagandara
• Pathyadi kwatha – shiroroga
• Punarnavarishta- gout or
hyperuricemia.(pittarakta and shophahara?)
• Ashwagandharishta- osteoarthritis
168/21/2020
Mode of action
• Rasna an excellent anti inflammatory and pain
relieving herb along with shunti, devadaru and
eranda excellent vatahara herbs.
• Vatakaphahara
• Apana vayu correction
• Deepana, pachana - amapachaka
• Srotoshodhana-helps in healing sinus track.
• Shoolahara
• Anti- inflammatory and Analgesic properties.
178/21/2020
Research Works
• Contribution of Ayurveda in management of
Spinal Cord Injury (SCI ) induced Paraplegia by
Punam Sawarkar-Rasnadi Guggulu 2 tabs (Each
250 mg )BID with Rasnasaptak Quath as
shamana.
• Shukla, K. P. et.al.: Evaluation of Rasnadi
Guggulu compound in the treatment of
Rheumatoid arthritis,Rheumatism,1985
188/21/2020
• Evaluation of clinical efficacy of Vaitarna Basti and Rasnadi Gutika in
the management of Gridhrasi W.S.R. Sciatica Anil Gangwar, Rachana
Gupta, Alok K. Srivastava, Uttam Sharma, Kulratan Singh, Priyanka
Rani;2015.
• EFFECT OF RASNADI GUGGULU AND BILVADI TAILA IN THE
MANAGEMENT OF BADHIRYA . A-PRELMINARY STUDY; 2014.
• MANAGEMENT OF A CASE OF LUMBAR STENOSIS WITH
AYURVEDIC INTERVENTION RATHA KSHIROD KUMAR*, BARIK
LAXMI DHAR, HAZRA JAYRAM ; 2016.
198/21/2020
• Khanna D et .al. Natural products as a goldmine for
arthritis treatment,curr opin pharmacology2007;7:344-
354.
-Mukul extract exhibited anti-inflammatory activity as it
reduced paw volume induced by formalin in rats. In the
carrageen induced rat paw edema model, the 250mg /kg dose
of the formulation (rasnadi guggul) showed significant activity
(p<0.001) at the end of 5th and 4th hour respectively. It also
had an inhibitory action against the granuloma pouch test.
New terpenes Myrrhanol A and Myrrhanone A from guggul-
gum resins showed potent anti- inflammatory effect on
adjuant induced air pouch granuloma of mice.
8/21/2020 20
Conclusion
• Rasnadi panchaka kwatha drugs have been
modified to a guggulu formulation imparting
properties of guggulu and is user friendly.
• A formula possessing vata kapha shamaka,
vatanulomana and rasayana action in many
ama associated vatavyadhis after proper
shodhana therapies.
218/21/2020
References
• Vaidya Laksmipati Sastri, Yogratnakara with Vidyotini commentary, edited
by Bhisagratna and Bramhasankar Sastri, Chaukhamba Sanskit Pratishtan,
edition 2017, page no-531, Vatavyadhi Chikitsa.
• Ayurvedic management of asthi – majjagatavat w. s. r. to manyastambha –
A case study/ Hulle Kavita Chinnappa, Neralkar Uday K./ Ayurlog: National
Journal of Research In Ayurved Science 2019; 3(2): pages: 01 - 06
• Jain & Gupta. Chemistry and pharmacological profile of Guggulu – a
review;2006.
• Evaluation of clinical efficacy of Vaitarna Basti and Rasnadi Gutika in the
management of Gridhrasi W.S.R. Sciatica Anil Gangwar, Rachana Gupta,
Alok K. Srivastava, Uttam Sharma, Kulratan Singh, Priyanka Rani;2015.
• Tomar Rinku et.al. : A Review on Guggulu; 2014.
• Sourbini and Vinay 2016 Greentree Group © IJAPC Int J Ayu Pharm Chem 2016 Vol.
5 Issue 2.
• Vaidya. Patil Arati S. : Clinical Study Of Rasnapanchaka Kwath In Sandhigata
Vata;2016.
228/21/2020
23
THANK YOU
8/21/2020

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RASNADI GUGGULU YOGA REVIEW

  • 1. RASNADI GUGGULU YOGA REVIEW Dr Anjana P Final year pg scholar R&B DEPARTMENT GOVT.AYURVEDA COLLEGE TRIPUNITHURA KERALA
  • 2. Contents • Introduction • Ingredients • Properties • Indications • Dose • Mode of action • Conclusion • References 28/21/2020
  • 3. Introduction • Guggulu is a popular herb classified as tridosha hara in Indian Ayurvedic medicine. • Detailed account of guggulu as a drug is given in the treatises of Charaka (1000 B.C.),Sushruta (600 B.C.), Vagbhata (17th century A.D.) and various Nighantus written in India between 12th and 14th centuries. • Guggulu always formulated with other ingredients in formulation based concept in Ayurveda with or without specific anupana. • Rasnadi guggulu is explained by Yogaratnakar in karnarogadhikara. 38/21/2020
  • 4. Also Mentioned in • Bhaishajya ratnavali vatavyadhi • Brihat yoga tarangini • Brhat nighantu ratanakara • Anandakanda vatavyadhi chikitsa(different formula) 48/21/2020
  • 5. • Rasnaamrteranda surahva vishvatulyam purenaatha vimrdya khaadet | Vataamayii karnashirogadii cha naadiyutaschaiva bhagandarii cha || [YOGARATNAKARA KARNAROGADHIKAARA, BRIHATNIGHANTU RATNAKARA VATAVYADHI] 58/21/2020
  • 6. Ingredients 68/21/2020 Rasna 1 part Guduchi 1 part Eranda 1 part Devadaru 1 part Shunti 1 part Shuddha guggulu 5 parts Goghrta Quantity sufficient
  • 7. Rasna • Pluchea lanceolata • Tikta rasa • Guru guna • Ushna veerya • Katu vipaka • vatakaphahar • Amapachana Guduchi • Tinosporacordifolia • Tikta, Kashaya rasa • Laghu guna • Ushna veerya • Madhura vipaka • Tridoshashaghna Balya, Dipana, Rasayana, Sangrahi, Raktasodhaka, Jvaraghna8/21/2020 7
  • 8. • Eranda • Ricinus communis • Madhura rasa • Guru, Snigdha guna • Ushna veerya • Madhura vipaka • vatakaphahara Vrushya, amapachaka • Devadaru • Cedrus deodara • Tikta rasa • Laghu, Snigdha guna • Ushna Veerya • Katu vipaka • vatakaphashamak Kaphahara, Vatahara, Dushtavranashodhaka 8/21/2020 8
  • 9. • Shunthi • Zingiber officinale • Katu Rasa • Laghu, Snigdha guna • Ushna veerya • Madhura vipaka • vatakaphashamak Anulomana, Dipana, Hridya, Pachana, Vatakaphapaha, pittalam. 8/21/2020 9
  • 10. • Guggulu is pounded in a mortar first and pestle with ghee and gradually add fine powders of the other five ingredients . • 500 mg tablets are made out of the mixture when fine semisolid mass consistency is attained. • Niragni guggulu vati example. • Sagni method can also be done. 108/21/2020
  • 11. • In large scale practice, • Color become dark black and tablet are round in shape. • In edge runner mill most sophisticated instrument, paste form occurs after one complete day with full rotation. • temperature of drying should be between 80-90 degree Celsius. • The mixing should be done in geometry way. • The powder put in mass mixer for 3 hours in a day with full speed. • After compression the drug is transfer in a tight bottle container. 8/21/2020 11
  • 12. Anandakanda Rasendrakhanda 20th upadesha Vatavyadhi chikitsa Here shuddha guggulu 5 parts , rasna 4 parts and ghrta q.s used. 128/21/2020
  • 13. • The Deepana, Amapachan and Rasayana properties of Rasna is overall beneficial for body systems. • Guggulu is a drug of choice in cases of Vata disorder because of its Vata-Kapha Shamaka and Vedanasthapana, Rasayana properties. 8/21/2020 13
  • 14. Indications • Vatavyadhi- neurological disorders like paralysis, neuropathy, joint related disorders • Karnagada – tinnitus • Shirogada- headache, migraine etc • Nadiroga • Bhagandara [Rasnadi kwatha also used for vedana shamaka and shothahara] • Sandhigata vata • Amavata • Mainly for shamana 148/21/2020
  • 15. Dose • No adverse effects reported with 750 mg- 1 g daily for 1 month – 3 months 158/21/2020
  • 16. Anupana • Based on the vyadhi and rogee avastha • Ushnodaka- samanya • Maharasnadi kashayam – shoola, sandhiroga • Lohasavam for bhagandara • Pathyadi kwatha – shiroroga • Punarnavarishta- gout or hyperuricemia.(pittarakta and shophahara?) • Ashwagandharishta- osteoarthritis 168/21/2020
  • 17. Mode of action • Rasna an excellent anti inflammatory and pain relieving herb along with shunti, devadaru and eranda excellent vatahara herbs. • Vatakaphahara • Apana vayu correction • Deepana, pachana - amapachaka • Srotoshodhana-helps in healing sinus track. • Shoolahara • Anti- inflammatory and Analgesic properties. 178/21/2020
  • 18. Research Works • Contribution of Ayurveda in management of Spinal Cord Injury (SCI ) induced Paraplegia by Punam Sawarkar-Rasnadi Guggulu 2 tabs (Each 250 mg )BID with Rasnasaptak Quath as shamana. • Shukla, K. P. et.al.: Evaluation of Rasnadi Guggulu compound in the treatment of Rheumatoid arthritis,Rheumatism,1985 188/21/2020
  • 19. • Evaluation of clinical efficacy of Vaitarna Basti and Rasnadi Gutika in the management of Gridhrasi W.S.R. Sciatica Anil Gangwar, Rachana Gupta, Alok K. Srivastava, Uttam Sharma, Kulratan Singh, Priyanka Rani;2015. • EFFECT OF RASNADI GUGGULU AND BILVADI TAILA IN THE MANAGEMENT OF BADHIRYA . A-PRELMINARY STUDY; 2014. • MANAGEMENT OF A CASE OF LUMBAR STENOSIS WITH AYURVEDIC INTERVENTION RATHA KSHIROD KUMAR*, BARIK LAXMI DHAR, HAZRA JAYRAM ; 2016. 198/21/2020
  • 20. • Khanna D et .al. Natural products as a goldmine for arthritis treatment,curr opin pharmacology2007;7:344- 354. -Mukul extract exhibited anti-inflammatory activity as it reduced paw volume induced by formalin in rats. In the carrageen induced rat paw edema model, the 250mg /kg dose of the formulation (rasnadi guggul) showed significant activity (p<0.001) at the end of 5th and 4th hour respectively. It also had an inhibitory action against the granuloma pouch test. New terpenes Myrrhanol A and Myrrhanone A from guggul- gum resins showed potent anti- inflammatory effect on adjuant induced air pouch granuloma of mice. 8/21/2020 20
  • 21. Conclusion • Rasnadi panchaka kwatha drugs have been modified to a guggulu formulation imparting properties of guggulu and is user friendly. • A formula possessing vata kapha shamaka, vatanulomana and rasayana action in many ama associated vatavyadhis after proper shodhana therapies. 218/21/2020
  • 22. References • Vaidya Laksmipati Sastri, Yogratnakara with Vidyotini commentary, edited by Bhisagratna and Bramhasankar Sastri, Chaukhamba Sanskit Pratishtan, edition 2017, page no-531, Vatavyadhi Chikitsa. • Ayurvedic management of asthi – majjagatavat w. s. r. to manyastambha – A case study/ Hulle Kavita Chinnappa, Neralkar Uday K./ Ayurlog: National Journal of Research In Ayurved Science 2019; 3(2): pages: 01 - 06 • Jain & Gupta. Chemistry and pharmacological profile of Guggulu – a review;2006. • Evaluation of clinical efficacy of Vaitarna Basti and Rasnadi Gutika in the management of Gridhrasi W.S.R. Sciatica Anil Gangwar, Rachana Gupta, Alok K. Srivastava, Uttam Sharma, Kulratan Singh, Priyanka Rani;2015. • Tomar Rinku et.al. : A Review on Guggulu; 2014. • Sourbini and Vinay 2016 Greentree Group © IJAPC Int J Ayu Pharm Chem 2016 Vol. 5 Issue 2. • Vaidya. Patil Arati S. : Clinical Study Of Rasnapanchaka Kwath In Sandhigata Vata;2016. 228/21/2020