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Case Conference
Recurrent syncope in a 23-year-old
       Mongolian woman

      吳宏彬醫師
  中國醫藥大學附設醫院心臟科
History
 23-year-old Mongolian woman presented
  with recurrent syncope in recent 2 years.
 Syncope preceded with short of breath and
  palpitation
 Witnessed trismus and seizure before
  fainting
 Mother died suddenly at her twenties



                                        CMUH
Holter 24 hr monitor ECG: Non-sustained VT

Brain CT: negative

EEG: equivocal abnormality

                                    CMUH
QTc : 406 ms




               CMUH
CMUH
Daily attacks of non-sustained VT
101/03/18            101/03/21




101/03/19            101/03/22



101/03/20



                                  CMUH
Three Different QRS morphologies of
        the Triggering VPC




                                CMUH
Treadmill exercise test
 Negativefor ischemia
 No VT or VF was induced during TET




                                       CMUH
CMUH
Sudden Cardiac Death in Young
   Coronary artery anomalies, LAD bridge, CAD
   Primary electrical diseases:
       WPW

   Long QT syndrome
   Catecholaminergic polymorphic VT
   Brugada syndrome
   Short QT syndrome
   Idiopathic VF
   Neurologic problems

                                                 CMUH
CMUH
Basic intervals
Sinus CL         857 ms
QRS              87 ms
AH               99 ms
HV               43 ms
SNRT             600=1103 ms   500=1000 ms
CL-1:1 AV        420 ms
conduction
CL-AVB           410 ms
AEST-CL          500 ms
ERP-AVN          370 ms
CL-1:1Ret FP     No VA                  CMUH
LV Inferior-apico-septal location
Spontaneous VPC    Pace mapping




                                  CMUH
Purkinje potential




                     CMUH
Endocardial electrograms of VPC




                            CMUH
No more daily VT post RFCA
101/03/24




   ICD implantation was performed due
   to only one of three morphologic
   VPCs ablation

                                    CMUH
After ICD implantation




Spontaneous idiopathic VF with near syncope
was noted. Aborted ICD shock due to
spontaneous termination.


                                     CMUH
Disscussion
After ablation, 24 ± 28 months, 24
patients (89%) in 27 patients had no
recurrence of ventricular fibrillation
without drug.


                                         CMUH
Characteristics of Patients




Twenty-seven consecutive patients
underwent attempted ablation of primary
idiopathic VF in 6 centers

                                     CMUH
CMUH
VPC       Patient number
morphology
  RVOT             4
  RBBB            10
  LBBB            13
   Both            4




                              CMUH
CMUH
CMUH
CMUH
CMUH
CMUH
CMUH
CMUH
CMUH
Thank you for your attention!

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