Journal article review by Dr. Vimarsha Bhatkalkar

Name: Dr. Vimarsha Bhatkalkar
Designation: BAMS, 2nd year PG Scholar
JOURNALARTICLE REVIEW

• Title
• Source
• Article Information
• Authors and Affiliations
• Purpose
• Critical Appraisal
• Own review
CONTENTS
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TITLE
PHARMACEUTICAL CHARACTERIZATION AND
EXPLORATION OF ARKESHWARA RASA IN
MDA-MB-231 CELLS
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• Journal: Journal of Ayurveda and Integrative Medicine
• National/ International: International
• Nature: Peer reviewed
• Article accessibility: Open access
• Indexed: Web of Science, PubMed/ Medline, Scopus, Embase, Emerging Sources Citation Index (ESCI),
CAB International, Directory of Open Access Journals (DOAJ)
• Impact factor: 2.4
• Cite score: 4
• Editor: Bhushan Patwardhan
• Established: 2010
SOURCE
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• Year: 2023
• Indexed: Elsevier
• Received: 31 March 2023
• Revised: 05 October 2023
• Accepted: 26 October 2023
• Available online: 30 December2023
• DOI: https://doi.org/10.1016/j.jaim.2023.100823
ARTICLE INFORMATION
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• Remya Jayakumar: Department of Rasashastra and Bhaishajya Kalpana, Banaras Hindu University,
Varanasi, 221005, India
• Manoj Kumar Dash: Department of Rasashastra and Bhaishajya Kalpana, Government Ayurveda College,
Raipur, India
• Pankaj Kumar: Department of Rasashastra and Bhaishajya Kalpana, Banaras Hindu University, Varanasi,
221005, India
• Shiwakshi Sharma: Department of Rasashastra and Bhaishajya Kalpana, Banaras Hindu University,
Varanasi, 221005, India
• Saumya Gulati: Dept of Rasashastra and Bhaishajya Kalpana, Babu Yugraj Singh Ayurvedic Medical College
and Hospital, Lucknow, Uttar Pradesh, 226010, India
AUTHORS AND AFFILIATIONS
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• Akanksha Pandey: Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005,
India
• Kaushavi Cholke:Amity Lipidomics Research Facility (ALRF), Amity University, Haryana, Manesar,
Gurugram, 122413, India. Institute of Biochemistry and Molecular Medicine, University of Bern, 3012,
Switzerland.
• Zeeshan Fatima: Department of Medical Laboratory Sciences, College of Applied Medical Sciences,
University of Bisha, Bisha, 61922, Saudi Arabia Amity Institute of Biotechnology, Amity University, Haryana,
Manesar, Gurugram, 122413, India
• S.K. Trigun: Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, India
• Namrata Joshi: Department of Rasashastra and Bhaishajya Kalpana, Banaras Hindu University, Varanasi,
221005, India
CONTD….
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Since Arkeshwar rasa posses anti inflammatory and anti tumor properties, it
was assessed against breast cancer cell lines.
REASON FOR SELECTING THIS
ARTICLE
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09-05-2024 31
CRITCIALAPPRAISAL

PHARMACEUTICAL CHARACTERIZATION AND EXPLORATION OF
ARKESHWARA RASA IN MDA-MB-231 CELLS
• Precise
• Self explanatory
• Understandable
TITLE
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• Structured (As per guidelines of the journal)
• No. of words: 238 (As per guidelines – 250 words)
• Keywords: mentioned ( 6 keywords mentioned)
• Provides a complete and brief view of the whole study.
ABSTRACT
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• Mentioned in brief about breast cancer and its prevalence.
• The need for the study has been mentioned
• The preparation of the formulation arkeshwara rasa has been highlighted.
• The objectives has been stated clearly.
INTRODUCTION
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• Properly segregated under appropriate subheadings.
• In the method of preparation of arkeshwara rasa, the amount of raw materials and the location of where it has
been procured has been mentioned.
• SOP of kajjali and tamra Bhasma preparation has been mentioned. They have presented a flowchart outlining
the preparation process for clarity and ease of understanding.
MATERIALS AND METHODS
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• Specified as per methodology in the form tables, graphs and illustrations wherever necessary.
• Observations and results are organised with proper subheadings.
OBSERVATIONS AND RESULTS
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• Discussed about the role of each chemical component which was revealed in LC-MS analysis.
• Each chemical component was depicted in tabular format, showcasing its chemical structure, its presence in
other cell lines, source, probable mode of action, and respective references was given.
DISCUSSION
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• Objectives fulfilled as per title.
• The chemical components present in arkeshwara rasa can synergize the anti-tumour potential.
• The nano-sized constituents and specific morphology of tetrahedrite could enhance various cellular processes
such as antioxidant, anti-inflammatory, anti-metastasis, anti-invasion, and anti-angiogenesis effects, potentially
leading to apoptosis induction in affected cell lines.
• Lastly under conclusion they have mentioned that AR need to be further experimented with reverse
transcription, flow cytometry, western blotting, etc
CONCLUSION
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• Vancouver style.
• Followed the guidelines of the articles for original research works.
REFERENCES
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• Provides detailed information about chemical components, structural changes, particle size.
• Provides detailed procedure of MTT assay SRB assay and AO assay.
• Statistical analysis is conducted in cell line studies to analyze and interpret data accurately.
OWN VIEWS
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Journal article review by Dr. Vimarsha Bhatkalkar

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