0
Mitotic Mistakes What happens when things go wrong?
What is the big deal? <ul><li>Although errors in mitosis are rare, the process may go wrong, especially during early cellu...
Different types of Errors <ul><li>Non-Disjunction </li></ul><ul><li>Deletion </li></ul><ul><li>Translocation </li></ul><ul...
Deletion <ul><li>Sometimes during mitosis the chromosomes can be damaged. </li></ul><ul><li>If the chromosome gets broken ...
Translocation <ul><li>If the chromosome breaks, it can reattach. </li></ul><ul><li>Sometimes it reattaches to the wrong ch...
Inversion <ul><li>When the fragment gets reattached it gets attached to the right chromosome but upside down. </li></ul><u...
Non-Disjunction <ul><li>When the sisters fail to separate.  </li></ul><ul><li>One cell is given three copies (trisomy) of ...
Aneuploidy <ul><li>Most recognized forms of Aneuploidy are Downs Syndrome (Trisomy 21) and Edwards syndrome (Trisomy 18). ...
Upcoming SlideShare
Loading in...5
×

Mitotic Mistakes

7,464

Published on

0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total Views
7,464
On Slideshare
0
From Embeds
0
Number of Embeds
1
Actions
Shares
0
Downloads
45
Comments
0
Likes
0
Embeds 0
No embeds

No notes for slide

Transcript of "Mitotic Mistakes"

  1. 1. Mitotic Mistakes What happens when things go wrong?
  2. 2. What is the big deal? <ul><li>Although errors in mitosis are rare, the process may go wrong, especially during early cellular divisions in the zygote . </li></ul><ul><li>Mitotic errors can be especially dangerous to the organism because future offspring from this parent cell will carry the same disorder. </li></ul>
  3. 3. Different types of Errors <ul><li>Non-Disjunction </li></ul><ul><li>Deletion </li></ul><ul><li>Translocation </li></ul><ul><li>Inversion </li></ul>
  4. 4. Deletion <ul><li>Sometimes during mitosis the chromosomes can be damaged. </li></ul><ul><li>If the chromosome gets broken the fragments can be lost. </li></ul><ul><li>If this happens the genetic material they contain is deleted. </li></ul>
  5. 5. Translocation <ul><li>If the chromosome breaks, it can reattach. </li></ul><ul><li>Sometimes it reattaches to the wrong chromosome. </li></ul><ul><li>This is called translocation </li></ul>
  6. 6. Inversion <ul><li>When the fragment gets reattached it gets attached to the right chromosome but upside down. </li></ul><ul><li>When this happens it incorrected codes for information. </li></ul>
  7. 7. Non-Disjunction <ul><li>When the sisters fail to separate. </li></ul><ul><li>One cell is given three copies (trisomy) of a chromosome while the other gets only one (monosomy). </li></ul><ul><li>These cells are called Aneuploidic, and they can cause cancer. </li></ul>
  8. 8. Aneuploidy <ul><li>Most recognized forms of Aneuploidy are Downs Syndrome (Trisomy 21) and Edwards syndrome (Trisomy 18). </li></ul><ul><li>Different cells with abnormal amounts of chromosomes is called mosaicism. </li></ul><ul><li>Some forms of mosaicism can cause cancers of the white blood cells (luekemia). </li></ul>
  1. A particular slide catching your eye?

    Clipping is a handy way to collect important slides you want to go back to later.

×